[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"International Spine Study Group Foundation\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":104},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,44,60,82],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":29,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":43},"100430451","prospective-evaluation-of-complex-adult-spinal-deformity-cad-treated-with-minimally-invasive-surgery-100430451",false,"NCT04885244","Prospective Evaluation of Complex Adult Spinal Deformity (CAD) Treated With Minimally Invasive Surgery","Prospective Evaluation of Complex Adult Spinal Deformity (CAD) Treated With Minimally Invasive Surgery (MIS)","MIS","Inclusion Criteria:\n\n1. \\>18 years of age at the time of treatment\n2. Diagnosis of adult congenital, degenerative, idiopathic, neuromuscular, inflammatory or iatrogenic spinal deformity\n3. EOS full body or standing 36\" AP \\& Lateral images of entire spine\n4. Surgery to be schedule to take place within 6 months (otherwise PROMs\u002FRadiographic images to be recollected)\n\n   AND Either:\n5. One of the following Radiographic criteria:\n\n   1. PI-LL ≥ 25 degrees\n   2. Thoracolumbar\u002Flumbar scoliosis ≥ 20 degrees\n   3. SVA \\>10cm\n   4. PT \\> 30 OR\n6. One of the Following Procedural criteria:\n\n   1. Surgery to include \\> 3 levels percutaneous posterior spinal instrumentation or 3 level stand-alone interbody. (Levels = vertebra (i.e. percutaneous screws at L2, L3, L4 would be eligible for posterior instrumentation and\u002For L3-L4, L4-L5 would be eligible as stand-alone for interbodies)\n   2. Posterior UIV and LIV must be placed percutaneously\n   3. Single-position surgery ≥ 3 levels fused (Levels=vertebra; S1 is counted as a level; S2 \\&\u002For pelvis\u002Filium is not)\n   4. Staged ≥ 3 levels fused with percutaneous pedicle screws\n   5. 3 column osteotomy with percutaneous fixation\n   6. ACR incorporating open or percutaneous fixation as long as UIV and LIV are percutaneous screws\n\nExclusion Criteria:\n\n1. Deformity due to acute trauma\n2. Active spine tumor or infection\n3. Patient is unwilling or unable to complete questionnaires\n4. Women who are pregnant\n5. Prisoners\n6. Open Posterior spinal fusion is planned (Open Anterior, i.e. ALIF, is acceptable)","ALL","18 Years",{"count":20,"type":21},500,"ESTIMATED","OBSERVATIONAL","Evaluate surgical treatment outcomes and identify best practice guidelines for complex adult spinal deformity (ASD) patients treated with minimally invasive approach, including radiographic and clinical outcomes, surgical and postoperative complications, risk factors for and revision surgery rates, and the role of standard work to improve patient outcomes and reduce surgical and postoperative complications.",[25,26,27,28],"Adult Spinal Deformity","Scoliosis","Kyphosis","Sagittal Imbalance",[26,27,28,30],"Spinal Deformity","RECRUITING","2026-02-12",{"date":34,"type":35},"2026-02-17","ACTUAL",{"date":37,"type":35},"2021-07-28",{"date":39,"type":21},"2034-12-31",{"name":41,"class":42},"International Spine Study Group Foundation","OTHER",12,{"id":45,"slug":46,"hasResults":11,"nctId":47,"briefTitle":48,"officialTitle":48,"acronym":4,"eligibilityCriteria":49,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":50,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":48,"conditions":52,"keywords":53,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":54,"startDateStruct":55,"completionDateStruct":57,"leadSponsor":58,"locationsCount":59},"100430670","prospective-multicenter-case-control-analysis-of-the-versatie-posterior-fixation-system-to-prevent-proximal-junctional-failure-in-long-posterior-spinal-fusion-constructs-for-adult-patients-100430670","NCT04888104","Prospective, Multicenter, Case-Control Analysis of the VersaTie Posterior Fixation System to Prevent Proximal Junctional Failure in Long Posterior Spinal Fusion Constructs for Adult Patients","Inclusion Criteria:\n\n1. \\>18 years of age at the time of treatment\n2. EOS full body or standing 36\" AP \\& Lateral images of entire spine\n3. Posterior spine fusion with pedicle screw fixation construct of 5 or more levels\n4. Pedicle screw fixation to be supplemented proximally with NuVasive VersaTie system\n5. Upper instrumented vertebra (UIV) terminating at a newly instrumented level\n6. Lowest instrumented vertebra (LIV) sacrum\u002Fpelvis\n7. Surgery scheduled to take place in the next 6 months\n\nExclusion Criteria:\n\n1. Active spine tumor or infection\n2. Deformity due to acute trauma\n3. Prisoners\n4. Women who are pregnant\n5. Patient is unwilling or unable to complete questionnaires",{"count":51,"type":21},225,[25,26,27],[26,27,28],{"date":34,"type":35},{"date":56,"type":35},"2021-07-09",{"date":39,"type":21},{"name":41,"class":42},9,{"id":61,"slug":62,"hasResults":11,"nctId":63,"briefTitle":64,"officialTitle":65,"acronym":66,"eligibilityCriteria":67,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":68,"targetDuration":70,"studyType":22,"phases":4,"briefSummary":71,"conditions":72,"keywords":73,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":75,"startDateStruct":76,"completionDateStruct":78,"leadSponsor":80,"locationsCount":81},"100377408","complex-adult-deformity-surgery-cads-100377408","NCT04194138","Complex Adult Deformity Surgery (CADS)","Multi-Center Prospective Evaluation of Complex Adult Spinal Deformity Surgery","CADS","Criteria:\n\nInclusion Criteria:\n\n1. Diagnosis of adult congenital, degenerative, idiopathic or iatrogenic spinal deformity\n2. Full body EOS radiographic assessment (sagittal and coronal visualization from skull to foot)\n3. Complex patients are defined as and meeting any one of the subsequent criteria:\n\n   1. Radiographic criteria:\n\n      * PI-LL ≥ 25 degrees\n      * TPA ≥ 30 degrees\n      * SVA\\>15cm\n      * Thoracic scoliosis ≥ 70 degrees\n      * Thoracolumbar\u002Flumbar scoliosis ≥ 50 degrees\n      * Global coronal malalignment \\>7cm\n   2. Procedural criteria:\n\n      * Posterior spinal fusion \\> 12 levels\n      * 3 column osteotomy or ACR\n   3. Geriatric criteria:\n\n      * Age \\>65 years and minimum 7 levels of spinal instrumentation during surgery\n\nExclusion Criteria:\n\n1. Age \\\u003C18 years of age\n2. Active spine tumor or infection\n3. Deformity due to acute trauma\n4. Neuromuscular conditions\u002Fdiseases (Parkinson's, Multiple Sclerosis, Post-polio syndrome)\n5. Syndromic scoliosis\n6. Inflammatory arthritis\u002Fauto immune diseases (Rheumatoid arthritis, Lupus, Ankylosing Spondylitis)\n7. Prisoners\n8. Women who are pregnant\n9. Non English speaking patients",{"count":69,"type":21},1500,"10 Years","Evaluate surgical treatment outcomes and identify best practice guidelines for complex adult spinal deformity (ASD) patients, including radiographic and clinical outcomes, surgical and postoperative complications, risk factors for and revision surgery rates, and the role of standard work to improve patient outcomes and reduce surgical and postoperative complications.",[25,26,27,28],[26,27,28,74],"Spinal deformity",{"date":34,"type":35},{"date":77,"type":35},"2018-07-30",{"date":79,"type":21},"2032-07-31",{"name":41,"class":42},18,{"id":83,"slug":84,"hasResults":11,"nctId":85,"briefTitle":86,"officialTitle":87,"acronym":88,"eligibilityCriteria":89,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":90,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":92,"conditions":93,"keywords":95,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":97,"startDateStruct":98,"completionDateStruct":100,"leadSponsor":102,"locationsCount":103},"100377474","radiographic-and-clinical-evaluation-of-surgical-treatment-for-cervical-deformity-a-multi-center-study-20-100377474","NCT04194996","Radiographic and Clinical Evaluation of Surgical Treatment for Cervical Deformity: A Multi-Center Study 2.0","Prospective Radiographic and Clinical Evaluation of Surgical Treatment for Cervical Deformity: A Multi-Center Study 2.0","PCD 2","Inclusion Criteria:\n\n* ≥18 years old at time of treatment\n* Diagnosis of cervical deformity- must meet one or more of the following criteria:\n\n  * C2-C7 sagittal kyphosis (Cobb \\> 15 degrees)\n  * T1S-CL \\> 35o\n  * Segmental cervical kyphosis \\> 10 degrees between any 2 vertebra between C2-T1 or \\> 15 degrees across any 3 vertebra between C2-T1\n  * Cervical scoliosis \\> 10 degrees (Cobb angle must include end vertebra within the cervical spine)\n  * C2-C7 SVA \\> 4cm\n  * McGregor's slope \\> 20 degrees or CBVA \\> 25 degrees OR\n  * Planned Revision surgery for proximal junctional failure with an anticipated UIV in the cervical spine and an anticipated LIV in the thoracic or lumbar spine.\n* Plan for surgical correction of cervical deformity in the next 6 months\n* Willing to provide consent and complete study forms at baseline and follow-up intervals\n* Upright AP\u002FLateral entire spine (EOS or 36\")\n* Upright AP\u002FLateral C spine ONLY IF C spine is not completely visible on entire spine films\n* Flex\u002FExt lateral C spine. Admin may allow exceptions w\u002F valid documentation.\n\nExclusion Criteria:\n\n* Active spine tumor or infection\n* Deformity due to acute trauma\n* Unwilling to provide consent or to complete study forms\n* Prisoner\n* Pregnant or immediate plans to get pregnant",{"count":91,"type":21},200,"Multi-center, prospective, non-randomized study to evaluate outcomes of surgically treated patients with adult cervical spinal deformity.",[94],"Cervical Deformity",[96,27,26],"Cervical deformity",{"date":34,"type":35},{"date":99,"type":35},"2019-08-01",{"date":101,"type":21},"2030-07-31",{"name":41,"class":42},16,""]