[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Interni hematologicka klinika FNKV\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":42},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":22,"conditions":23,"keywords":25,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":41},"100536338","prognostic-significance-of-ctdna-in-hl-100536338",false,"NCT06263530","Prognostic Significance of ctDNA in HL","Prognostic Significance of Circulating Tumor DNA in Hodgkin Lymphoma","Inclusion Criteria:\n\n* Patients ≥ 18 years with newly histologically confirmed classical Hodgkin lymphoma (cHL) will be enrolled\n* signing the informed consent\n\nExclusion Criteria:\n\n* Pacients without signing the informed consent","ALL","18 Years",{"count":19,"type":20},500,"ESTIMATED","OBSERVATIONAL","Specific somatic mutations using ctDNA will be analyzed in predefined subgroups of cHL (e.g., age \\\u003C60 and ≥ 60 years, EBV). These mutations will be correlated with response to the treatment in the first line, in the relapse, during brentuximab vedotin and\u002For nivolumab treatment. Circulating tumor DNA will be correlated with the extent of tumor mass and chemo\u002Fradiotherapy.",[24],"Prognostic Cancer Model",[26,27,28],"Hodgkin lymphoma","circulating tumor DNA","next generation sequencing","RECRUITING","2024-02-08",{"date":32,"type":33},"2024-02-16","ACTUAL",{"date":35,"type":33},"2022-01-02",{"date":37,"type":20},"2027-12-31",{"name":39,"class":40},"Interni hematologicka klinika FNKV","NETWORK",5,""]