[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Istanbul Galata University\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":131},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,46,81,103],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":45},"100639130","the-effect-of-exercise-on-cognitive-functions-in-individuals-with-systemic-lupus-erythematosus-100639130",false,"NCT07622251","The Effect of Exercise on Cognitive Functions in Individuals With Systemic Lupus Erythematosus","Sistemik Lupus Eritematozus Tanılı Bireylere Uygulanan Aerobik Egzersizlerin Kognitif Fonksiyonlar ve Hastalık Aktivitesi Üzerine Etkisi","Inclusion Criteria:\n\n* Having been diagnosed with SLE at least one year prior according to the American Rheumatology Association (ACR) diagnostic criteria\n* Being between 25-65 years of age\n* Not having received a neuropsychiatric diagnosis\n* Having medication adjusted and being on stable medication for 3 months\n* Not being involved in a regular exercise program\n* Having a Mini Mental Test score lower than 26.\n\nExclusion Criteria:\n\n* History of secondary rheumatic disease\n* Presence of active acute or chronic infection,\n* Body mass index (BMI) ≥ 30 kg\u002Fm2,\n* Acute renal failure,\n* Cardiac and pulmonary involvement,\n* Presence of musculoskeletal and joint disorders that prevent exercise testing,\n* Pregnancy","ALL","25 Years","65 Years",{"count":20,"type":21},38,"ESTIMATED","INTERVENTIONAL",[24],"NA","Study Objective:\n\nTo examine the effect of aerobic exercise on disease activity and cognitive functions in patients diagnosed with SLE. Study Goals:\n\n1. To conduct comprehensive pre- and post-treatment (after 12 weeks) evaluations of SLE patients included in the study, and to determine their disease activity and cognitive levels.\n2. To apply aerobic exercise to SLE patients for three months.\n3. To analyze the effects of the aerobic exercise program on disease activity and cognitive functions.",[27],"System Lupus Erythematosus(SLE)",[29,30,31,32],"cognitive function","aerobic exercise","systemic lupus erythematosus","disease activity","NOT_YET_RECRUITING","2026-05-30",{"date":36,"type":37},"2026-06-03","ACTUAL",{"date":39,"type":21},"2026-06-05",{"date":41,"type":21},"2027-08-10",{"name":43,"class":44},"Istanbul Galata University","OTHER",1,{"id":47,"slug":48,"hasResults":11,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":4,"eligibilityCriteria":52,"healthyVolunteers":11,"sex":16,"minAge":53,"maxAge":54,"enrollmentInfo":55,"targetDuration":4,"studyType":22,"phases":57,"briefSummary":58,"conditions":59,"keywords":65,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":73,"lastUpdatePostDateStruct":74,"startDateStruct":76,"completionDateStruct":78,"leadSponsor":80,"locationsCount":4},"100608809","effects-of-emdr-on-psychological-symptoms-and-eeg-findings-in-trauma-exposed-individuals-100608809","NCT07206381","Effects of EMDR on Psychological Symptoms and EEG Findings in Trauma-Exposed Individuals","EMDR Group Therapy for Earthquake-Exposed Trauma Survivors: A Randomized Trial of Psychological and QEEG Outcomes","Inclusion Criteria:\n\n* Meeting DSM-5 criteria for posttraumatic stress symptoms following the April 2025 Silivri earthquake\n* Age between 18 and 50 years\n* Either medication-free for at least 1 month or on a stable dose of psychotropic medication\n* No medical contraindications for EEG recording (e.g., no epilepsy, no metal implants)\n\nExclusion Criteria:\n\n* Current diagnosis of schizophrenia, bipolar disorder, or a neurological disorder\n* Receiving psychotherapy\n* Inability to attend sessions regularly due to logistical or cognitive limitations","18 Years","50 Years",{"count":56,"type":21},40,[24],"This study will examine the effects of Eye Movement Desensitization and Reprocessing (EMDR) group therapy on adults who experienced the April 2025 Silivri earthquake in Turkey. Participants will be randomly assigned to either an EMDR intervention group or a waitlist control group. Psychological symptoms will be measured using the PTSD Checklist for DSM-5 (PCL-5), the Depression, Anxiety, and Stress Scale (DASS-21), the Short Form Health Survey (SF-36), and the Pittsburgh Sleep Quality Index (PSQI). Quantitative EEG (QEEG) recordings will also be collected before and after the intervention to assess changes in brain activity related to emotional regulation and trauma processing. The goal of the study is to evaluate whether EMDR produces both clinical and neurophysiological improvements in trauma-exposed individuals.",[60,61,62,63,64],"PTSD - Post Traumatic Stress Disorder","Depression","Anxiety Disorders and Symptoms","Sleep Quality","Quality of Life",[66,67,61,68,69,70,71,72],"Eye Movement Desensitization and Reprocessing (EMDR)","Posttraumatic Stress Disorder (PTSD)","Anxiety","Sleep quality","quality of life","earthquake","QEEG","2026-01-27",{"date":75,"type":37},"2026-01-30",{"date":77,"type":21},"2026-03-04",{"date":79,"type":21},"2026-08-15",{"name":43,"class":44},{"id":82,"slug":83,"hasResults":11,"nctId":84,"briefTitle":85,"officialTitle":86,"acronym":4,"eligibilityCriteria":87,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":88,"enrollmentInfo":89,"targetDuration":4,"studyType":22,"phases":91,"briefSummary":92,"conditions":93,"keywords":4,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":95,"lastUpdatePostDateStruct":96,"startDateStruct":98,"completionDateStruct":100,"leadSponsor":102,"locationsCount":45},"100617542","effect-of-semaglutide-and-tirzepatide-combined-with-exercise-in-obesity-100617542","NCT07319975","Effect of Semaglutide and Tirzepatide Combined With Exercise in Obesity","Comparison of the Effects of Semaglutide and Tirzepatide Treatments in Combination With Exercise in Obesity Management","Inclusion Criteria:\n\n* Those between the ages of 25 and 60 years\n* Those with a body mass index (BMI) between 30 and 40 kg\u002Fm2 according to the World Health Organization (WHO) classification\n* Individuals who volunteered to participate in the study\n\nExclusion Criteria:\n\n* Individuals with a BMI greater than 40 kg\u002Fm2 according to the WHO classification\n* Individuals with a Charlson comorbidity index score of 3 or higher\n* Uncontrolled arrhythmia, hypertension, heart failure, diabetes, and unstable angina pectoris\n* Cooperation impairment, orthopedic, and neurological problems that may interfere with evaluation and treatment\n* Individuals with a history of lower extremity injury or surgery in the last six months\n* Diagnosed with diabetes and complications such as nephropathy, retinopathy, and neuropathy\n* Individuals with concomitant chronic respiratory disease\n* Individuals with acute infections\n* Individuals with middle ear pathologies (such as tympanic membrane rupture, otitis media)\n* Individuals with a history of spontaneous or trauma-related pneumothorax\n* Smokers\n* Pregnancy\n* Individuals with a STOP-bang score of 3 or higher\n* Individuals on a structured diet program for weight loss during the study period\n* Individuals who have had endoscopic intervention and\u002For bariatric surgery within the last year","60 Years",{"count":90,"type":21},48,[24],"Obesity is a growing global health problem that affects people of all ages. It can lead to serious health issues such as cardiovascular disease, insulin resistance, inflammation, and reduced physical function. New medications, including GLP-1 receptor agonists like semaglutide and dual GLP-1\u002FGIP agonists like tirzepatide, have been shown to help people lose significant weight. However, some of this rapid weight loss may come from a reduction in muscle mass rather than fat. Losing muscle can lower physical performance, impair metabolic health, and increase the risk of developing sarcopenic obesity. This study aims to compare the effects of pharmacological treatment alone with a combined treatment program that includes both medication and exercise in individuals with obesity. The primary objective is to evaluate how these two approaches influence body composition.\n\nThe secondary objective is to examine the effects of pharmacological treatment versus combined treatment on cardiometabolic markers, peripheral muscle strength, functional capacity, respiratory function, respiratory muscle performance, and physical activity levels. The study seeks to determine whether adding structured exercise to medication can provide additional health benefits beyond weight loss.",[94],"Obesity","2025-12-21",{"date":97,"type":37},"2026-01-06",{"date":99,"type":21},"2025-12-29",{"date":101,"type":21},"2026-12",{"name":43,"class":44},{"id":104,"slug":105,"hasResults":11,"nctId":106,"briefTitle":107,"officialTitle":107,"acronym":4,"eligibilityCriteria":108,"healthyVolunteers":11,"sex":16,"minAge":53,"maxAge":4,"enrollmentInfo":109,"targetDuration":111,"studyType":112,"phases":4,"briefSummary":113,"conditions":114,"keywords":119,"overallStatus":122,"whyStopped":4,"lastUpdateSubmitDate":123,"lastUpdatePostDateStruct":124,"startDateStruct":126,"completionDateStruct":128,"leadSponsor":130,"locationsCount":45},"100560793","evaluation-of-validity-and-reliability-of-the-turkish-translation-of-the-digital-health-readiness-questionaire-in-different-chronic-diseases-100560793","NCT06581770","Evaluation of Validity and Reliability of the Turkish Translation of the Digital Health Readiness Questionaire in Different Chronic Diseases","Inclusion Criteria:\n\n* The study will include people over the age of 18, native Turkish speakers, literate, obese, diabetic, cardiovascular and respiratory patients.\n\nExclusion Criteria:\n\n* Individuals with insufficient cooperation (Mini Mental Test score \\<24) and any cognitive problems that may prevent the administration of the survey will be excluded from the study.",{"count":110,"type":21},200,"2 Months","OBSERVATIONAL","The World Health Organization (WHO) defines digital health as the field of knowledge and application related to any aspect of the adoption of digital technology in the stages of improvement. The combination of digital health with technology brings about a new transformation in digital media. This transformation allows for the development of communication and information in health services, the ability to conduct health-related research on digital media and the evaluation of this data. The ease of access to information and the provision of a timely feedback mechanism in the face of problems have enabled the spread of digital health systems, and have also enabled chronic disease management and epidemic disease monitoring.\n\nIt is recommended that the term digital readiness be used to cover the combination of digital access and use, digital literacy and digital health literacy. Digital health readiness is also defined as the main determinant of health and is thought to contribute to the improvement of health processes with the development of digital health literacy and to be a useful solution against health problems that may arise in the follow-up of chronic diseases.\n\nAlthough there are tools in the literature that evaluate digital health readiness, there is no Turkish assessment tool that facilitates the follow-up of non-communicable chronic diseases. Therefore, the aim of our study is to evaluate the translation, validity, and reliability of the Digital Health Readiness Questionaire into Turkish in individuals with chronic non-infectious diseases.",[115,116,117,118],"Non-Communicable Chronic Diseases","Survey and Questionnaire","Validation Studies","Digital Health",[120,121],"digital health","Digital Health Readiness Questionaire","RECRUITING","2025-02-05",{"date":125,"type":37},"2025-02-10",{"date":127,"type":37},"2024-10-15",{"date":129,"type":21},"2025-09-15",{"name":43,"class":44},""]