[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Istanbul Kent University\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":74},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,45],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":39,"leadSponsor":41,"locationsCount":44},"100638073","mulligan-mobilization-in-lateral-elbow-tendinopathy-100638073",false,"NCT07589725","Mulligan Mobilization in Lateral Elbow Tendinopathy","Effects of Mulligan Mobilization With Movement Technique on Pain, Muscle Stiffness, Grip Strength, and Function in Patients With Lateral Elbow Tendinopathy","Inclusion Criteria:\n\n* Inclusion Criteria\n* Age between 18 and 60 years\n* Presence of unilateral lateral elbow pain and tenderness for at least 3 months\n* Diagnosis of lateral elbow tendinopathy confirmed by the following four criteria:\n* Local tenderness over the lateral epicondyle\n* Positive Cozen's test\n* Positive Maudsley's test\n* Positive Mill's stretch test\n\nExclusion Criteria:\n\n* History of surgery around the elbow\n* History of elbow dislocation, fracture, or extensor tendon rupture\n* History of fracture of the humerus, ulna, or radius within the past year\n* Receipt of any treatment for LET within the past 6 months (e.g., physiotherapy, exercise, manual therapy, dry needling, orthosis)\n* Presence of cervical referred pain and\u002For radiculopathy (positive Spurling test)\n* Signs of peripheral nerve involvement\n* Corticosteroid injection within the past 6 months\n* History of rheumatologic disease\n* Presence of cancer or tumor","ALL","18 Years","60 Years",{"count":20,"type":21},45,"ESTIMATED","INTERVENTIONAL",[24],"NA","The aim of this study is to investigate the short-, medium-, and long-term effects of Mulligan Mobilization with Movement (MWM) added to an exercise program on pain, functionality, and biomechanical parameters in individuals with lateral elbow tendinopathy, compared to sham mobilization and exercise-only interventions.\n\nThe primary hypothesis is that the addition of true MWM to exercise will result in greater improvements in pain intensity, grip strength, pressure pain threshold, kinesiophobia, wrist joint position sense, and the mechanical properties of the extensor muscles compared to placebo (sham MWM) and exercise alone.\n\nThis study is designed as a three-arm randomized placebo-controlled trial. A total of 45 participants will be allocated to one of three groups: MWM plus exercise, sham MWM plus exercise, and exercise alone. Assessments will be conducted at baseline, immediately post-intervention, and at 3- and 6-month follow-ups.\n\nThe primary outcome measure is pain intensity. Secondary outcomes include functionality, grip strength, pressure pain threshold, kinesiophobia, wrist proprioception, and the mechanical properties of the extensor carpi radialis brevis muscle assessed using Myoton.\n\nThis study aims to determine the effects of manual therapy independent of placebo and to evaluate the sustainability of these effects over time. Additionally, by objectively assessing the mechanical and proprioceptive characteristics of the muscle-tendon unit alongside clinical outcomes, the study is expected to provide a novel contribution to the literature. The findings are anticipated to enhance the understanding of the mechanisms underlying conservative treatment approaches in lateral elbow tendinopathy and to support evidence-based clinical decision-making.",[27],"Lateral Elbow Tendinopathy (Tennis Elbow)",[29,30,31,32],"mulligan mobilization","lateral elbow tendinopathy","placebo","exercise","NOT_YET_RECRUITING","2026-05-11",{"date":36,"type":37},"2026-05-15","ACTUAL",{"date":36,"type":21},{"date":40,"type":21},"2027-10-01",{"name":42,"class":43},"Istanbul Kent University","OTHER",1,{"id":46,"slug":47,"hasResults":11,"nctId":48,"briefTitle":49,"officialTitle":50,"acronym":4,"eligibilityCriteria":51,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":52,"enrollmentInfo":53,"targetDuration":4,"studyType":22,"phases":55,"briefSummary":56,"conditions":57,"keywords":59,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":4},"100550722","aronia-and-non-alcoholic-fatty-liver-disease-100550722","NCT06450769","Aronia and Non-alcoholic Fatty Liver Disease","Effect of Mediterranean Diet Supplemented With Aronia and Low-Fat Diet on Hepatic Steatosis, Inflammation, Oxidative Stress and Microbiota in Non-alcoholic Fatty Liver Disease","Inclusion Criteria:\n\n* 18- 64 years of age\n* Body mass index (BMI) 25-40 kg\u002Fm2\n* Newly diagnosed with NAFLD and has not been treated before\n* Volunteering\n\nExclusion Criteria:\n\n* Chronic disease other than NAFLD\n* Pregnancy or breastfeeding\n* Bleeding disorder\n* Regular medication use\n* Any food allergies or intolerances\n* Being on a special diet treatment\n* Smoking in the last year\n* Alcohol use in the last year\n* Having used antibiotics in the last 3 months\n* Use of prebiotics or probiotics in the last 3 months\n* Use of proton pump inhibitors in the last 3 months\n* Use of vitamin-mineral supplementation in the last 3 months\n* Use of nutritional supplements in the last 3 months","64 Years",{"count":54,"type":21},54,[24],"Adults newly diagnosed with NAFLD will be included in the study. At the beginning of the research, the socio-demographic characteristics and nutritional habits of the individuals will be questioned with a face-to-face questionnaire. In addition, at the beginning of the study, blood samples, 3-day food consumption record, physical activity record, anthropometric measurements (height, body weight, waist, hip and neck circumference and body composition analysis) and stool samples will be taken from the patients. Oxidative stress (TAS, TOS, SOD, Malondialdehyde, Catalase, Glutathione peroxidase, Glutathione, AGE and DNA oxidative damage) and inflammation (CRP, TNF-alpha, IL-17, IL-23, IL-10, IL-13, TGF-beta) parameters in blood samples will be analyzed. Patients will then be randomized into four groups to follow a Mediterranean diet supplemented with aronia, a Mediterranean diet, a low-fat diet supplemented with aronia, or a low-fat diet. Necessary training will be given to the participants so that they can apply the individually planned diet. Dietary adherence and anthropometric measurements will be evaluated every 2 weeks. At the end of the twelve-week follow-up, all parameters evaluated at the beginning of the study will be repeated and compared with previous values.",[58],"Non-Alcoholic Fatty Liver Disease",[60,61,62,63,64,65],"Aronia","NAFLD","Mediterranean diet","Oxidative stress","Inflammation","Microbiota","2024-06-05",{"date":68,"type":37},"2024-06-10",{"date":70,"type":21},"2024-06-15",{"date":72,"type":21},"2026-06-15",{"name":42,"class":43},""]