[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Istanbul Saglik Bilimleri University\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":318},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,11,0,[8,48,78,112,140,167,194,216,247,270,292],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":30,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":43,"leadSponsor":45,"locationsCount":4},"100643803","nutrition-counseling-diet-quality-and-advanced-glycation-end-products-in-gestational-diabetes-100643803",false,"NCT07636577","Nutrition Counseling, Diet Quality, and Advanced Glycation End Products in Gestational Diabetes","The Relationship Between Nutrition Counseling in Gestational Diabetes Mellitus and Diet Quality and Advanced Glycation End Products","Inclusion Criteria:\n\n* Pregnant women aged 18 to 35 years\n* Singleton and first pregnancy\n* Gestational age between 24 and 28 weeks at enrollment\n* Diagnosis of gestational diabetes mellitus or normal glucose tolerance\n* Not using insulin therapy\n* Stopped smoking at least 3 months before enrollment and not using alcohol\n* Willingness to participate in the study\n* Ability to provide written informed consent\n\nExclusion Criteria:\n\n* Current use of insulin therapy\n* Active smoking\n* Alcohol use\n* Refusal or inability to provide written informed consent",true,"FEMALE","18 Years","35 Years",{"count":21,"type":22},48,"ESTIMATED","INTERVENTIONAL",[25],"NA","This study will evaluate the relationship between structured nutrition counseling, diet quality, and advanced glycation end products in pregnant women with gestational diabetes mellitus and women with normal glucose tolerance. Participants will be assigned to either a structured nutrition counseling group or a standard care group according to glucose tolerance status. The counseling program will include education and follow-up on healthy eating during pregnancy, gestational diabetes management, portion control, food choices, meal planning, and cooking methods. Diet quality, dietary habits, biochemical parameters, advanced glycation end products, gestational weight gain, and fetal outcomes will be assessed during follow-up.",[28,29],"Gestational Diabetes Mellitus","Pregnancy",[31,32,33,34,35],"Advanced Glycation End Products","Diet Quality","Nutrition Counseling","Dietary Habits","Highly Processed Food Consumption","NOT_YET_RECRUITING","2026-06-08",{"date":39,"type":40},"2026-06-09","ACTUAL",{"date":42,"type":22},"2026-08",{"date":44,"type":22},"2027-07",{"name":46,"class":47},"Istanbul Saglik Bilimleri University","OTHER",{"id":49,"slug":50,"hasResults":11,"nctId":51,"briefTitle":52,"officialTitle":53,"acronym":4,"eligibilityCriteria":54,"healthyVolunteers":11,"sex":55,"minAge":18,"maxAge":4,"enrollmentInfo":56,"targetDuration":4,"studyType":58,"phases":4,"briefSummary":59,"conditions":60,"keywords":63,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":72,"completionDateStruct":74,"leadSponsor":76,"locationsCount":77},"100637998","validation-of-the-turkish-version-of-the-s3-niv-questionnaire-100637998","NCT07610122","Validation of the Turkish Version of the S3-NIV Questionnaire","Reliability and Validity of the Turkish Version of the Severe Respiratory Insufficiency Questionnaire for Non-Invasive Ventilation (S3-NIV)","Inclusion Criteria:\n\n* Diagnosed with chronic respiratory failure requiring home non-invasive ventilation (NIV).\n* Using a home NIV device for at least 3 months.\n* Being in a clinically stable phase (no exacerbation or hospitalization in the last 1 month).\n* Able to understand and answer the questionnaire.\n* Provided written informed consent.\n\nExclusion Criteria:\n\n* Acute respiratory failure or clinical instability.\n* Severe cognitive impairment or psychiatric disorders preventing reliable communication.\n* Active malignancy or terminal illness with a short life expectancy.\n* Refusal to provide informed consent.","ALL",{"count":57,"type":22},120,"OBSERVATIONAL","This study aims to evaluate the psychometric properties, including reliability and validity, of the Turkish version of the Severe Respiratory Insufficiency Questionnaire for Non-Invasive Ventilation (S3-NIV). The S3-NIV is a specific tool designed to assess difficulties and compliance in patients receiving home non-invasive ventilation. A total of 120 stable patients using home NIV for at least 3 months will be enrolled across multiple centers.",[61,62],"Respiratory Insufficiency","Chronic Respiratory Failure",[64,65,66,67,68],"Non-Invasive Ventilation","Validation","Questionnaire","Reliability","S3-NIV","2026-05-27",{"date":71,"type":40},"2026-05-28",{"date":73,"type":22},"2026-05-21",{"date":75,"type":22},"2026-12-30",{"name":46,"class":47},1,{"id":79,"slug":80,"hasResults":11,"nctId":81,"briefTitle":82,"officialTitle":83,"acronym":4,"eligibilityCriteria":84,"healthyVolunteers":16,"sex":55,"minAge":85,"maxAge":86,"enrollmentInfo":87,"targetDuration":88,"studyType":58,"phases":4,"briefSummary":89,"conditions":90,"keywords":93,"overallStatus":103,"whyStopped":4,"lastUpdateSubmitDate":104,"lastUpdatePostDateStruct":105,"startDateStruct":107,"completionDateStruct":109,"leadSponsor":111,"locationsCount":77},"100640786","neurotrophic-factors-impulsivity-and-reward-sensitivity-in-children-with-internet-gaming-disorder-100640786","NCT07590180","Neurotrophic Factors, Impulsivity, and Reward Sensitivity in Children With Internet Gaming Disorder","Investigation of the Relationship Between Serum BDNF and GDNF Levels and Impulsivity, Reward\u002FPunishment Sensitivity in Children Diagnosed With Internet Gaming Disorder","Inclusion Criteria:\n\nFor IGD Patient Group:\n\nAge: Being between 10 and 14 years of age. Literacy: Ability to read and write fluently. Informed Consent: Voluntary participation with written informed consent obtained from both the participants and their parents\u002Flegal guardians after a comprehensive briefing on the study procedures and scales.\n\nDiagnostic Criteria: Meeting the DSM-5 diagnostic criteria for Internet Gaming Disorder (IGD) and scoring above the clinical cutoff on the Internet Gaming Disorder Scale-Short Form (IGDS9-SF).\n\nFor Healthy Control Group:\n\nAge: Children between 10 and 14 years of age. Literacy: Ability to read and write fluently. Clinical Status: No history or current diagnosis of any neuropsychiatric disorder, confirmed through clinical psychiatric assessment.\n\nInformed Consent: Voluntary participation with written informed consent obtained from both the participants and their parents\u002Flegal guardians after a comprehensive briefing on the study procedures and scales.\n\nExclusion Criteria:\n\nComorbid Psychiatric Disorders: Meeting the DSM-5 diagnostic criteria for Autism Spectrum Disorder, Schizophrenia, Bipolar I Disorder, or Bipolar II Disorder.\n\nCognitive and Neurological Impairment: Having a moderate to severe intellectual disability and\u002For a neurological disease in either the child or the caregiver that would impede the ability to understand instructions or provide reliable responses during the interview.\n\nLack of Informed Consent: Refusal to participate voluntarily or failure to sign the informed consent\u002Fassent form by the children or their parents\u002Flegal guardians after receiving a detailed explanation of the study's purpose and the assessment scales to be administered.","10 Years","14 Years",{"count":57,"type":22},"1 Week","Research and knowledge regarding the neurobiology of behavioral addictions and Internet Gaming Disorder (IGD) remain limited compared to substance and alcohol use disorders. However, IGD is increasingly causing significant functional impairment, particularly in the child and adolescent population. The primary objective of this study is to measure the serum levels of Brain-Derived Neurotrophic Factor (BDNF) and Glial-Derived Neurotrophic Factor (GDNF)-both known for their roles in neurogenesis and neuroprotective effects-in a patient group aged 10-14 and a healthy control group. Additionally, this study aims to investigate the relationship between these neurotrophic factor levels and disease severity, as well as various behavioral and emotional parameters measured through psychometric assessments, to identify differences between the patient and healthy populations.\n\nResearchers will compare IGD patient group with healthy control group, both aged 10-14.\n\nParticipants and their parents will be asked to fill self-report measures and serum samples of participants will be collected for BDNF and GDNF level measurements.\n\nThe main questions of the study are:\n\n* Is there a difference in serum BDNF and GDNF levels between IGD patient group and healthy controls?\n* Is there a relation between serum BDNF and GDNF levels and IGD severity?\n* Is there a difference in impulsivity, reward\u002Fpunishment sensitivity between IGD patient group and healthy controls\n* Is there a relation between serum BDNF and GDNF levels and impulsivity, reward\u002Fpunishment sensitivity scores in IGD patient group?",[91,92],"Internet Gaming Disorder","Internet Addiction",[94,95,96,97,98,99,100,101,102],"Internet addiction","Child and adolescent psychiatry","Neurogenesis","Neurotrophic factors","BDNF","GDNF","Impulsivity","Reward\u002Fpunishment sensitivity","Internet gaming disorder","RECRUITING","2026-05-10",{"date":106,"type":40},"2026-05-15",{"date":108,"type":40},"2026-05-01",{"date":110,"type":22},"2027-01",{"name":46,"class":47},{"id":113,"slug":114,"hasResults":11,"nctId":115,"briefTitle":116,"officialTitle":117,"acronym":4,"eligibilityCriteria":118,"healthyVolunteers":11,"sex":55,"minAge":119,"maxAge":4,"enrollmentInfo":120,"targetDuration":4,"studyType":23,"phases":122,"briefSummary":123,"conditions":124,"keywords":127,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":133,"lastUpdatePostDateStruct":134,"startDateStruct":136,"completionDateStruct":137,"leadSponsor":139,"locationsCount":4},"100630004","the-impact-of-training-on-self-efficacy-symptom-level-and-activities-of-daily-living-100630004","NCT07482033","The Impact of Training on Self-Efficacy, Symptom Level, and Activities of Daily Living","The Effect of Pecha Kucha Training on Noninvasive Mechanical Ventilation Support for Individuals With Chronic Obstructive Pulmonary Disease on Self-Efficacy, Symptom Level, and Daily Living Activities","Inclusion Criteria\n\n* Age 18 years or older\n* Diagnosed with chronic obstructive pulmonary disease (COPD) at least one year prior\n* Currently receiving treatment with noninvasive mechanical ventilation (NIMV) support\n* Ability to communicate verbally and in writing in a clear and sustainable manner\n* No severe visual or hearing impairment that would prevent understanding of educational materials\n* Basic ability to use a smartphone\n* Active use of the WhatsApp application on a personal smartphone\n* Technical capability to view educational materials sent via phone (e.g., internet access, video playback)\n* No prior education on NIMV delivered using the Pecha Kucha presentation technique\n* Adequate cognitive function to allow independent participation (e.g., no history of dementia or confusion)\n* Availability to attend educational and assessment sessions as scheduled\n\nExclusion Criteria\n\n* Failure to attend planned educational sessions or inability to complete the study protocol\n* Voluntary withdrawal from the study, declared verbally or in writing\n* Death during the study period\n* Development of a serious health condition preventing continuation in the education program (e.g., hospitalization, acute exacerbation, deterioration in mental status)\n* Loss of phone or internet access preventing receipt of educational materials\n* Significant communication problems that substantially interfere with participation in the educational process","18 Days",{"count":121,"type":22},60,[25],"This study is a randomized, controlled experimental trial with a pretest-posttest design, conducted to evaluate the effects of Pecha Kucha-based education on self-efficacy, symptom level, and activities of daily living in individuals diagnosed with chronic obstructive pulmonary disease (COPD) receiving noninvasive mechanical ventilation support.\n\nThe study will include two groups, and intergroup differences will be evaluated:\n\n1. Control group\n2. Intervention group\n\nStudy Hypotheses H1: Pecha Kucha-based education on noninvasive mechanical ventilation (NIMV) support provided to individuals with chronic obstructive pulmonary disease (COPD) increases patients' self-efficacy levels.\n\nH2: Pecha Kucha-based education on noninvasive mechanical ventilation (NIMV) support provided to individuals with chronic obstructive pulmonary disease (COPD) reduces patients' symptom levels.\n\nH3: Pecha Kucha-based education on noninvasive mechanical ventilation (NIMV) support provided to individuals with chronic obstructive pulmonary disease (COPD) improves patients' activities of daily living.",[125,126],"Activities of Daily Living","Chronic Obstructive Pulmonary Disease (COPD)",[128,129,130,131,132],"self-efficacy","symptom severity","activities of daily living","Chronic Obstructive Pulmonary Disease","Pecha Kucha","2026-04-21",{"date":135,"type":40},"2026-04-24",{"date":108,"type":22},{"date":138,"type":22},"2026-12-31",{"name":46,"class":47},{"id":141,"slug":142,"hasResults":11,"nctId":143,"briefTitle":144,"officialTitle":144,"acronym":4,"eligibilityCriteria":145,"healthyVolunteers":11,"sex":55,"minAge":119,"maxAge":4,"enrollmentInfo":146,"targetDuration":4,"studyType":23,"phases":148,"briefSummary":149,"conditions":150,"keywords":154,"overallStatus":103,"whyStopped":4,"lastUpdateSubmitDate":159,"lastUpdatePostDateStruct":160,"startDateStruct":162,"completionDateStruct":164,"leadSponsor":166,"locationsCount":77},"100598388","effects-of-two-different-eye-care-practices-on-eye-complications-in-mechanically-ventilated-intensive-care-patients-100598388","NCT07070843","Effects of Two Different Eye Care Practices on Eye Complications in Mechanically Ventilated Intensive Care Patients","Inclusion Criteria:\n\n* Age 18 years or older\n* Receiving mechanical ventilation\n* Glasgow Coma Scale (GCS) score \\\u003C 12\n* At least 24 hours have passed since ICU admission\n* Baseline Schirmer test result indicating tear production \\> 5 mm prior to study inclusion\n\nExclusion Criteria:\n\n* Diagnosed with brain death\n* Presence of facial or ocular trauma\n* Patients with head trauma\n* Patients who have undergone brain surgery\n* Patients diagnosed with an eye infection or chemosis\n\nWithdrawal Criteria:\n\n* Patient's death during the study period\n* Extubation of the patient before completion of the care period",{"count":147,"type":22},156,[25],"This study was designed as a prospective, randomized controlled experimental study aiming to compare different approaches to eye care in intensive care patients receiving mechanical ventilation. In this study, patients receiving mechanical ventilation in the intensive care unit will be randomly assigned to four groups using a simple randomization method:\n\n1. Control Group: Standard Eye Care\n2. Intervention Group 1: Eye Care with Eye Care Kit\n3. Intervention Group 2: Eye Care According to Eye Care Protocol\n4. Intervention Group 3: Eye Care with Both Protocol and Eye Care Kit Research Hypotheses H1: Eye care provided using a care protocol is more effective in preventing the development of complications compared to standard eye care.\n\nH2: Eye care provided using an eye care kit is more effective in preventing the development of ocular complications compared to standard eye care.\n\nH3: The combined use of an eye care kit and a care protocol is more effective in preventing the development of ocular complications compared to using the care protocol alone.\n\nH4: The use of an eye care kit is more effective in preventing the development of ocular complications compared to the use of a care protocol.",[151,152,153],"Eye Care","Nursing Care","Intensive Care Unit",[155,156,157,158],"Critical care nursing","Eye infections","Intensive care units","Nursing care","2026-01-27",{"date":161,"type":40},"2026-01-29",{"date":163,"type":40},"2025-07-01",{"date":165,"type":22},"2026-10",{"name":46,"class":47},{"id":168,"slug":169,"hasResults":11,"nctId":170,"briefTitle":171,"officialTitle":172,"acronym":4,"eligibilityCriteria":173,"healthyVolunteers":16,"sex":55,"minAge":18,"maxAge":174,"enrollmentInfo":175,"targetDuration":4,"studyType":58,"phases":4,"briefSummary":177,"conditions":178,"keywords":180,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":186,"lastUpdatePostDateStruct":187,"startDateStruct":189,"completionDateStruct":191,"leadSponsor":193,"locationsCount":77},"100612862","comparison-of-sports-anxiety-sports-injury-anxiety-and-knowledge-levels-regarding-factors-causing-sports-injury-in-individuals-who-regularly-engage-in-conditioning-work-with-and-without-a-history-of-injury-100612862","NCT07259096","Comparison of Sports Anxiety, Sports Injury Anxiety, and Knowledge Levels Regarding Factors Causing Sports Injury in Individuals Who Regularly Engage in Conditioning Work With and Without a History of Injury","Comparison of Knowledge Levels of Regular Conditioning Workers With and Without a History of Injury Regarding Sports Anxiety, Sports Injury Anxiety, and Factors Causing Injury in Sports","Inclusion Criteria:\n\n* Must have been doing regular conditioning exercises for at least 6 months\n* Must be between 18-45 years of age\n\nExclusion Criteria:\n\n* Being a professional athlete\n* Having a neurological problem","45 Years",{"count":176,"type":22},94,"Anxiety, or anxiety disorder, is a common occurrence today. Studies have proven that sports have a high potential for stress and anxiety. Among the reasons for its prevalence in athletes are performance pressure, public scrutiny, dissatisfaction with athletic careers, injuries, and harassment and abuse in sports. Anxiety can negatively impact performance and competition results. However, the relationship between anxiety and performance has not been fully established. Studies on the relationship between anxiety and injury in athletes are also increasing. However, studies examining injury history and sports anxiety levels in individuals who regularly perform conditioning exercises are lacking.\n\nBased on our literature review, our study will ask individuals who regularly engage in conditioning training about their injury history. Participants will be divided into two groups: those with and those without injuries. The two groups will be compared in terms of their sports anxiety and fear of injury, and their knowledge of the factors that contribute to injuries in sports will be measured.",[179],"People Who Do Regular Conditioning Work",[181,182,183,184,185],"Conditioning Work","Sports Anxiety","Sports Injury Anxiety","Factors Causing Sports Injury","History of Injury","2025-11-21",{"date":188,"type":40},"2025-12-02",{"date":190,"type":22},"2026-01-01",{"date":192,"type":22},"2026-03-01",{"name":46,"class":47},{"id":195,"slug":196,"hasResults":11,"nctId":197,"briefTitle":198,"officialTitle":198,"acronym":4,"eligibilityCriteria":199,"healthyVolunteers":11,"sex":55,"minAge":18,"maxAge":200,"enrollmentInfo":201,"targetDuration":4,"studyType":58,"phases":4,"briefSummary":202,"conditions":203,"keywords":4,"overallStatus":103,"whyStopped":4,"lastUpdateSubmitDate":208,"lastUpdatePostDateStruct":209,"startDateStruct":211,"completionDateStruct":213,"leadSponsor":215,"locationsCount":77},"100600675","bacteria-in-dental-plaque-and-atheroma-plaque-100600675","NCT07100574","Bacteria in Dental Plaque and Atheroma Plaque","Inclusion Criteria:\n\n* Diagnosed with endarterectomy\n* Not receiving chemotherapy\n* Not having received this treatment before\n\nExclusion Criteria:\n\n* Having systemic infection\n* Patients with severe heart disease","85 Years",{"count":121,"type":22},"Periodontitis is considered a focus of infection where oral bacteria, bacterial by-products or inflammatory mediators can interact with other parts of the organism via the blood. Periodontal pathogen components such as DNA, RNA or specific antigens of P. gingivalis, Aggregatibacter actinomycetemcomitans (A. actinomycetemcomitans), Treponema denticola (T. denticola), Fusobacterium nucleatum (F. nucleatum) or Campylobacter rectus have been isolated from different tissues such as atheroma plaques, placenta, amniotic sac and respiratory tract. It has been reported that periodontitis may contribute to endothelial dysfunction leading to the formation of atherosclerosis.",[204,205,206,207],"Gingival Inflammation","Dental Plaque","Atheroma Plaque","Oral Bacteria","2025-08-01",{"date":210,"type":40},"2025-08-03",{"date":212,"type":40},"2024-12-10",{"date":214,"type":22},"2026-03-30",{"name":46,"class":47},{"id":217,"slug":218,"hasResults":11,"nctId":219,"briefTitle":220,"officialTitle":221,"acronym":222,"eligibilityCriteria":223,"healthyVolunteers":11,"sex":55,"minAge":224,"maxAge":18,"enrollmentInfo":225,"targetDuration":4,"studyType":23,"phases":227,"briefSummary":228,"conditions":229,"keywords":233,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":239,"lastUpdatePostDateStruct":240,"startDateStruct":242,"completionDateStruct":244,"leadSponsor":246,"locationsCount":77},"100596050","aromatherapy-and-music-on-pain-vital-signs-and-parental-satisfaction-in-children-undergoing-peritoneal-dialysis-100596050","NCT07040410","Aromatherapy and Music on Pain, Vital Signs and Parental Satisfaction in Children Undergoing Peritoneal Dialysis","The Effect of Aromatherapy and Music on Pain, Vital Signs and Parental Satisfaction in Children Undergoing Peritoneal Dialysis Treatment: A Randomized Controlled Study","2024-KAEK-11","Inclusion Criteria:\n\n* Children will be included between the ages of 3 and 18 who receive instrumental peritoneal dialysis or continuous outpatient peritoneal dialysis treatment.\n* Children who have a sufficient cognitive level (3-18 years) to determine pain scores,\n* Children who have a healthy hearing and vision system,\n* Children who did not take painkillers, opioids or sedatives 6 hours before the study,\n* Children who have absence of severe pain in another part of the body,\n* Children who have absence of a history of allergies,\n* Children and parents who can speak and understand Turkish.\n\nExclusion Criteria:\n\n* Decline to participate in the study,\n* Peritonitis diagnosis,\n* Pain due to catheter immobilization,\n* Receiving the first session of peritoneal dialysis treatment","3 Years",{"count":226,"type":22},45,[25],"This study is an experimental randomized controlled study conducted to compare the effect of two different nonpharmacological treatment methods (aromatherapy and music therapy) on pain, vital signs and parental satisfaction to alleviate or eliminate pain during excretion and filling in children undergoing peritoneal dialysis treatment. The study population consists of pediatric patients aged 3 to 18 years undergoing peritoneal dialysis treatment at Basaksehir Cam and Sakura City Hospital between June 2025- 2026. According to literature, for experimental studies and parametric measurements, at least 30 participants should be included in both experimental and control groups. Therefore, this crossover randomized design will include 45 children per group: control, aromatherapy, and music therapy. Children included in the sample will be assigned to groups based on a crossover randomized design. This method is suitable for studies with a small sample size. Since three different interventions will be applied once per session over three sessions, to avoid bias, the order of interventions will be randomized and labeled as A, B, and C. The researcher will write the names of the interventions on three separate papers, draw them one by one, and assign them accordingly: Method A: Aromatherapy, Method B: Music Therapy, Method C: Control. Then, the six possible sequences (ABC, ACB, BAC, BCA, CAB, CBA) will be written on six papers and drawn randomly to determine the intervention order for each participant.",[230,231,232],"Pain","Vital Signs Monitoring","Parental Satisfaction",[234,235,236,237,238],"peritoneal dialysis treatment","pain management","pain in children","non-pharmacological method","satisfaction","2025-06-26",{"date":241,"type":40},"2025-06-27",{"date":243,"type":22},"2025-06-25",{"date":245,"type":22},"2026-06-25",{"name":46,"class":47},{"id":248,"slug":249,"hasResults":11,"nctId":250,"briefTitle":251,"officialTitle":252,"acronym":253,"eligibilityCriteria":254,"healthyVolunteers":16,"sex":55,"minAge":18,"maxAge":4,"enrollmentInfo":255,"targetDuration":4,"studyType":23,"phases":257,"briefSummary":258,"conditions":259,"keywords":4,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":263,"lastUpdatePostDateStruct":264,"startDateStruct":266,"completionDateStruct":268,"leadSponsor":269,"locationsCount":4},"100590968","abcdef-bundle-to-prevent-delirium-for-copd-patients-100590968","NCT06974318","ABCDEF Bundle to Prevent Delirium for COPD Patients","The Evaluation of the Effect of ABCDEF Bundle Implementation on Preventing Delirium in Patients Followed in the Medical Intensive Care Patients Due to Chronic Obstructive Pulmonary Disease","COPD","Inclusion Criteria:\n\n* Patients aged 18 and over,\n* No cognitive disease such as dementia or Alzheimer's,\n* Patients requiring intensive care monitoring for at least 24 hours,\n* Non-intubated patients,\n* Having a diagnosis of COPD.\n\nExclusion Criteria:\n\n* Patients being monitored in intensive care primarily due to central nervous system disease,\n* Intubated patients.",{"count":256,"type":22},84,[25],"Abstract Chronic Obstructive Pulmonary Disease (COPD) is a progressive respiratory disorder characterized by persistent airflow limitation and chronic respiratory symptoms, resulting from abnormalities in the bronchi, bronchioles, and alveoli. Patients with COPD may require admission to intensive care units (ICUs), particularly during acute exacerbations. In this context, both disease management and the prevention of potential complications, such as delirium, are of critical importance. Delirium is a common, preventable, and serious complication in ICUs that prolongs hospital stays, increases healthcare costs, and heightens the risk of infections. Hypoxia-induced cognitive impairment is among the key contributing factors to delirium in patients with COPD.\n\nTo improve patient outcomes, the ABCDEF Care Bundle was introduced in 2013 as a structured and evidence-based approach to ICU care. This study aims to evaluate the effectiveness of the ABCDEF Care Bundle in preventing delirium in patients with COPD admitted to the ICU. The research will be conducted as a randomized controlled trial between April and December 2025 in the third-level ICU of Taksim Training and Research Hospital. The study population will consist of COPD patients, with a total sample size of 84 patients (42 in each group), randomly assigned using a computer-assisted simple randomization method. A variety of validated instruments will be used to assess pain, sedation, cognitive status, mobility, and sleep quality.\n\nThe findings of this study are expected to contribute to the growing body of evidence supporting structured ICU care and to raise awareness among healthcare professionals regarding the implementation of the ABCDEF Care Bundle.\n\nKeywords:\n\nABCDEF Care Bundle, Delirium, COPD, Intensive Care, Nursing Care, Randomized Controlled Trial",[260,261,262],"Delirium","Copd","Nurse's Role","2025-05-08",{"date":265,"type":40},"2025-05-15",{"date":267,"type":22},"2025-05",{"date":42,"type":22},{"name":46,"class":47},{"id":271,"slug":272,"hasResults":11,"nctId":273,"briefTitle":274,"officialTitle":275,"acronym":4,"eligibilityCriteria":276,"healthyVolunteers":11,"sex":55,"minAge":18,"maxAge":277,"enrollmentInfo":278,"targetDuration":4,"studyType":23,"phases":280,"briefSummary":281,"conditions":282,"keywords":4,"overallStatus":103,"whyStopped":4,"lastUpdateSubmitDate":284,"lastUpdatePostDateStruct":285,"startDateStruct":287,"completionDateStruct":289,"leadSponsor":291,"locationsCount":77},"100552466","patients-with-irritable-bowel-syndrome-and-physiotherapy-100552466","NCT06473454","Patients With Irritable Bowel Syndrome and Physiotherapy","the Effect of Aerobic Exercise and Basic Body Awareness Therapy on Quality of Life and Gastrointestinal Symptoms in Patients With Irritable Bowel Syndrome: A Randomized Controlled Trial","inclusion criterias\n\n1\\. Being between the ages of 18-65 2. Compliance with Rome IV criteria 3. Declaring that you wish to participate in the study with written consent exclusion criterias\n\n1. Voluntary refusal to participate in the study\n2. Having a psychiatric illness\n3. Not having any orthopedic, neurological or cardiopulmonary disease that would constitute a contraindication for the protocols to be applied.\n4. Do not pose any risk of injury while working in line with posture analysis.\n5. In case the limitations in muscle shortness tests prevent the study\n6. Using laxatives regularly\n7. Being diagnosed with diabetes or a metabolic disease that will affect the gastrointestinal system\n8. No history of Inflammatory Bowel Disease (IBD), colon cancer or colon resection\n9. Using antibiotics and probiotics in the last 3 months\n10. Using anticholinergic, opiate or morphine-type drugs that will affect intestinal motility\n11. Getting diagnosed with celiac disease","65 Years",{"count":279,"type":22},72,[25],"The research will be planned on 72 individuals between the ages of 18-65 who were diagnosed with irritable bowel syndrome at Istanbul Medipol University Çamlıca SUAM Gastroenterology Polyclinic. Patients will be divided into 3 groups; High-intensity interval training and a disease-specific nutrition program for the first group, and a disease-specific nutrition program for the second group; Basic Body Awareness Therapy (BBAT) and a disease-specific nutrition program will be given, while the control group will be given only a disease-specific nutrition program. Evaluations will be made immediately before and after treatment. The first experimental group will be asked to walk with high-intensity interval training, which the investigators plan for 30 minutes, 4 days a week for 8 weeks. TBFT will be applied to the second experimental group every day of the week. The application will be done face to face one day a week, and the patient will be asked to do it himself on the other days, and the sessions will last approximately 30 minutes. In addition, all patients will be asked to follow the nutrition program determined by the dietician. Participants' sociodemographic information, IBS disease type and medications used will be recorded. In order to collect data for both the intervention groups and the control group immediately before and after the study; 6 Minute Walk Test (6MWT), posture analysis, muscle shortness test for large muscle groups in the lower and upper extremities, International Physical Activity Questionnaire Short Form (IPAQ-SF), Diet Compliance Questionnaire Form, Bristol Stool Scale Form, Gastrointestinal Symptom Assessment Scale (GSDS). ), Pittsburgh Sleep Quality Index (PSQI), IBS Quality of Life Scale (IBS-QOL), Morningness-Eveningness Questionnaire (SAA), Psychological Well-Being Scale (PIOS) and Body Awareness Questionnaire (VFA) will be used.",[283],"Irritable Bowel Syndrome","2024-09-30",{"date":286,"type":40},"2024-10-02",{"date":288,"type":40},"2024-07-20",{"date":290,"type":22},"2025-02-15",{"name":46,"class":47},{"id":293,"slug":294,"hasResults":11,"nctId":295,"briefTitle":296,"officialTitle":297,"acronym":4,"eligibilityCriteria":298,"healthyVolunteers":16,"sex":55,"minAge":18,"maxAge":4,"enrollmentInfo":299,"targetDuration":4,"studyType":23,"phases":300,"briefSummary":301,"conditions":302,"keywords":304,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":310,"lastUpdatePostDateStruct":311,"startDateStruct":313,"completionDateStruct":315,"leadSponsor":317,"locationsCount":4},"100551037","effect-of-normothermia-care-bundle-in-knee-replacement-surgery-100551037","NCT06454877","Effect of Normothermia Care Bundle in Knee Replacement Surgery","Effect of Normothermia Care Bundle on Inadvertent Perioperative Hypothermia, Surgical Site Infection and Bleeding in Knee Replacement Surgery","Inclusion Criteria:\n\n18 years or older Planned elective knee arthroplasty surgery Patients planned for neuraxial block anesthesia ASA (American Society of Anesthesiologists) class I-III\n\nExclusion Criteria:\n\nAlcohol and drug addiction, Patients who cannot be contacted Preoperative body temperature \\\u003C36 C° or ≥37.5 C°",{"count":57,"type":22},[25],"Osteoarthritis is a disease characterized by disruption of the integrity of articular cartilage as a result of erosion of articular cartilage. Knee osteoarthritis causes muscle weakness, crepitation and deformities in the knee joint, limiting the individual's movement and causing loss of function. The most prominent feature is pain. Therefore, knee replacement surgery is performed in advanced cases where pharmacologic treatment is not effective. Many complications can be seen during the operation process and some of them may occur due to hypothermia. Studies have reported that warming during the operation prevents hypothermia and reduces complications. In this study, it was aimed to examine the effect of active and passive heating applied before, during and after surgery on hypothermia, surgical site infections and bleeding. The population of the study will consist of patients who underwent knee replacement surgery in the Orthopedics and Traumatology Clinic of Üsküdar State Hospital between April 2024 and April 2025. Data will be collected using the patient identification form, normothermia care package observation form, preoperative follow-up form, postoperative follow-up form and postoperative long-term follow-up form. A randomization list generated from a computer-based random numbers table will be used to determine which group of patients will be included in the study. Patients will be followed up in 3 periods: preoperative, intraoperative and postoperative periods. The postoperative period will be evaluated in five stages as day 1, day 2, day 3, day 10 and day 30. The purpose of the study and the intervention to be applied will be explained to all groups to be included in the study by the researcher and written and verbal consent will be obtained from the volunteers. The groups included in the study will be subjected to the heating protocol according to the normothermia care package. Group A will receive active heating with the heating method using a hot air blowing device. Group B will receive passive heating using a reflective blanket. Group C was planned as a control group to be heated by applying the routine heating procedure of the hospital without any intervention. Body temperature and vital signs will be checked preoperatively and warming will be performed 30 minutes before surgery, and warming will be started 15 minutes before anesthesia induction during surgery and body temperature and vital signs will be checked. After the operation and in the ward, warming will be performed until the body temperature reaches 37 C°. The data obtained will be analyzed using SPSS (Statistical Package for Social Sciences) for Windows 22.0 program.",[303],"Knee Prosthesis",[305,306,307,308,309],"Hypotermia","surgical site infection","active heating","pasive heating","nursing care bundle","2024-06-10",{"date":312,"type":40},"2024-06-12",{"date":314,"type":22},"2024-06-01",{"date":316,"type":22},"2025-06-01",{"name":46,"class":47},""]