[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Istanbul University - Cerrahpasa\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":691},{"pageToken":4,"total":5,"offset":6,"count":7,"results":8},null,157,0,25,[9,48,78,105,135,163,191,224,250,275,303,331,355,379,409,432,459,496,520,546,575,599,627,650,671],{"id":10,"slug":11,"hasResults":12,"nctId":13,"briefTitle":14,"officialTitle":15,"acronym":4,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":20,"enrollmentInfo":21,"targetDuration":4,"studyType":24,"phases":25,"briefSummary":27,"conditions":28,"keywords":31,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100645413","yoga-vs-stretching-strengthening-physical-fitness-in-sedentary-young-adults-100645413",false,"NCT07680712","Yoga vs. Stretching-Strengthening: Physical Fitness in Sedentary Young Adults","Comparative Effects of Yoga Versus Stretching-Strengthening Exercises on Physical Fitness in Sedentary Young Adults","Inclusion Criteria:\n\n* Being between 18 and 30 years of age,\n* Having a body mass index (BMI) of less than 30 kg\u002Fm²,\n* Being healthy (having no known systemic, neurological, psychological, or orthopedic diseases),\n* Not having participated in regular exercise within the last six months,\n* Having a sedentary lifestyle according to the World Health Organization (WHO) definition (not performing at least 150 minutes of moderate-intensity or 75 minutes of vigorous-intensity aerobic activity per week),\n* Agreeing not to participate regularly in any other physical activity or exercise program for the duration of the study,\n* Voluntarily participating in the study and agreeing to sign the written and verbal informed consent form in accordance with the principles of the Declaration of Helsinki.\n\nExclusion Criteria:\n\n* Individuals with a history of injury, surgery, or pain complaints affecting the musculoskeletal system within the last six months,\n* Individuals with neurological, cardiovascular, respiratory, endocrine, psychiatric, or metabolic diseases,\n* Individuals who participate in any regular sporting activity,\n* Female participants who are pregnant or have a suspected pregnancy,\n* Individuals who state that they will not be able to participate regularly in the exercise program or will not be able to complete the study,\n* Individuals who do not provide written and verbal informed consent to participate in the study.",true,"ALL","18 Years","30 Years",{"count":22,"type":23},50,"ESTIMATED","INTERVENTIONAL",[26],"NA","The goal of this clinical trial is to learn if yoga or stretching-strengthening exercises are more effective in sedentary young adults who are currently healthy but at risk due to inactivity. The main questions it aims to answer are:\n\nWhich exercise type leads to better improvements in physical fitness, mental well-being, and sleep quality based on a person's starting profile?\n\nHow do initial levels of balance and muscle strength affect how well a person responds to these exercises?\n\nResearchers will compare a yoga group to a stretching-strengthening exercise group to see if one approach is more effective than the other for specific types of individuals.\n\nParticipants will:\n\nBe evaluated for their starting physical fitness (balance and strength) and psychological health.\n\nPerform either yoga or stretching-strengthening exercises regularly during the study period.\n\nComplete surveys about their mood, stress levels, and sleep quality.\n\nBe re-tested at the end of the program to measure changes and improvements.",[29,30],"Sedentary Lifestlye","Exercise",[32,33,34],"physical exercise","physical inactivity","healthy lifestyle","NOT_YET_RECRUITING","2026-06-29",{"date":38,"type":39},"2026-07-02","ACTUAL",{"date":41,"type":23},"2026-06-22",{"date":43,"type":23},"2027-03",{"name":45,"class":46},"Istanbul University - Cerrahpasa","OTHER",1,{"id":49,"slug":50,"hasResults":12,"nctId":51,"briefTitle":52,"officialTitle":53,"acronym":4,"eligibilityCriteria":54,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":55,"enrollmentInfo":56,"targetDuration":4,"studyType":24,"phases":58,"briefSummary":59,"conditions":60,"keywords":62,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":71,"lastUpdatePostDateStruct":72,"startDateStruct":73,"completionDateStruct":75,"leadSponsor":77,"locationsCount":47},"100645372","betamethasone-vs-dextrose-injections-in-trigger-finger-100645372","NCT07681804","Betamethasone vs Dextrose Injections in Trigger Finger","Comparison of Ultrasound-Guided Betamethasone and Dextrose Injections in the Treatment of Trigger Finger: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Age between 18 and 75 years\n* Clinical diagnosis of trigger finger\n* Presence of symptoms for at least 4 weeks\n\nExclusion Criteria:\n\n* Previous surgery on the affected finger\n* Injection treatment to the affected finger within the previous 3 months\n* Active local or systemic infection\n* Active malignancy\n* Active inflammatory rheumatic disease (e.g., rheumatoid arthritis, ankylosing spondylitis, polymyalgia rheumatica, vasculitis)\n* Uncontrolled diabetes mellitus and\u002For uncontrolled hypertension\n* Autoimmune connective tissue diseases (e.g., systemic lupus erythematosus, antiphospholipid syndrome, systemic sclerosis, Sjögren syndrome, polymyositis, dermatomyositis, adult-onset Still's disease)\n* Coagulopathy that increases the risk of injection procedures\n* Pregnancy\n* Known allergy or hypersensitivity to lidocaine, betamethasone, or dextrose\n* Mental impairment or severe psychiatric disorder that may interfere with study participation or informed consent","75 Years",{"count":57,"type":23},42,[26],"This study aims to compare the effectiveness of ultrasound-guided betamethasone and dextrose injections in patients with trigger finger.\n\nTrigger finger is a common hand condition characterized by pain, clicking, and locking of the finger due to tendon entrapment at the A1 pulley. Corticosteroid injections are widely used as a first-line treatment; however, they may be associated with potential side effects.\n\nDextrose injection is an alternative treatment that may promote tissue healing through regenerative mechanisms. However, there is limited high-quality evidence regarding its effectiveness in trigger finger.\n\nIn this randomized controlled trial, patients will be assigned to receive either betamethasone or dextrose injection under ultrasound guidance. The primary outcome will be pain intensity measured by the Numeric Rating Scale (NRS). Secondary outcomes will include triggering severity, hand function, grip and pinch strength, and fine motor skills evaluated over a 12-week follow-up period.\n\nThe results of this study may help determine whether dextrose injection is a safe and effective alternative to corticosteroid treatment in trigger finger.",[61],"Trigger Finger",[63,64,65,66,67,68,69,70],"Trigger finger","Stenosing tenosynovitis","Ultrasound-guided injection","Betamethasone injection","Dextrose injection","A1 pulley","QuickDASH","Modified Quinnell classification","2026-06-27",{"date":38,"type":39},{"date":74,"type":23},"2026-06",{"date":76,"type":23},"2027-05",{"name":45,"class":46},{"id":79,"slug":80,"hasResults":12,"nctId":81,"briefTitle":82,"officialTitle":83,"acronym":4,"eligibilityCriteria":84,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":85,"enrollmentInfo":86,"targetDuration":4,"studyType":24,"phases":88,"briefSummary":89,"conditions":90,"keywords":93,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":98,"lastUpdatePostDateStruct":99,"startDateStruct":100,"completionDateStruct":102,"leadSponsor":104,"locationsCount":4},"100644698","inspiratory-muscle-training-in-individuals-with-multiple-sclerosis-100644698","NCT07672535","Inspiratory Muscle Training in Individuals With Multiple Sclerosis","Comparison of the Effects of High-Intensity and Low-Intensity Inspiratory Muscle Training in Individuals With Multiple Sclerosis","Inclusion Criteria:\n\n* Diagnosis of multiple sclerosis (MS) according to the 2024 McDonald criteria\n* Expanded Disability Status Scale (EDSS) score ≥2 and \\\u003C6\n* Age between 18 and 65 years\n* Mini-Mental State Examination (MMSE) score \\>24\n* Willingness to participate in the study\n\nExclusion Criteria:\n\n* Experiencing an MS relapse within the past three months\n* Presence of chronic cardiac or pulmonary diseases that may affect respiratory muscle strength and function, such as COPD, asthma, interstitial lung disease, or heart failure\n* Presence of pulmonary infection\n* Presence of orthopedic problems\n* Presence of psychiatric disorders\n* Pregnancy","65 Years",{"count":87,"type":23},48,[26],"Multiple sclerosis (MS) is a chronic disease affecting the central nervous system, characterized by inflammation, demyelination, and axonal degeneration, and primarily affects young adults. Muscle weakness, sensory disturbances, spasticity, pain, visual impairment, ataxia, fatigue, cognitive dysfunction, and respiratory complications are among the most commonly reported symptoms in individuals with MS. Although inspiratory muscle training has been shown to have beneficial effects in individuals with MS, the effects of different inspiratory muscle training intensities on respiratory muscle strength and pulmonary function have not been sufficiently investigated.\n\nThe primary aim of this study is to investigate the effectiveness and clinical feasibility of high-intensity interval inspiratory muscle training in individuals with MS. The secondary aim is to compare the effects of high-intensity interval inspiratory muscle training, low-intensity inspiratory muscle training, and conventional rehabilitation on respiratory muscle strength, pulmonary function, cough effectiveness, exercise capacity, lower extremity functional muscle strength, balance, fatigue, dysphagia severity, sleep quality, and quality of life in individuals with MS.\n\nParticipants will be randomly assigned to one of three groups: a high-intensity interval inspiratory muscle training group, a low-intensity inspiratory muscle training group, or a conventional rehabilitation group. All three groups will receive conventional rehabilitation, while the inspiratory muscle training groups will additionally receive their respective inspiratory muscle training programs. This study aims to be the first randomized controlled trial to evaluate the effects of high-intensity interval inspiratory muscle training in individuals with MS.",[91,92],"Multiple Sclerosis","Inspiratory Muscle Training",[94,95,96,97],"multiple sclerosis","inspiratory muscle training","respiratory muscle training","respiratory muscle strength","2026-06-26",{"date":36,"type":39},{"date":101,"type":23},"2026-08",{"date":103,"type":23},"2028-01",{"name":45,"class":46},{"id":106,"slug":107,"hasResults":12,"nctId":108,"briefTitle":109,"officialTitle":109,"acronym":4,"eligibilityCriteria":110,"healthyVolunteers":12,"sex":18,"minAge":111,"maxAge":4,"enrollmentInfo":112,"targetDuration":4,"studyType":24,"phases":114,"briefSummary":115,"conditions":116,"keywords":121,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":128,"lastUpdatePostDateStruct":129,"startDateStruct":131,"completionDateStruct":132,"leadSponsor":134,"locationsCount":4},"100628162","comparson-of-the-effcacy-of-conventonal-exercse-and-plates-n-pre-fral-and-fral-older-adults-100628162","NCT07458048","Comparıson of the Effıcacy of Conventıonal Exercıse and Pılates ın Pre-fraıl and Fraıl Older Adults","Inclusion Criteria:\n\n* Age 60 years and older Classified as prefrail or frail according to the FRAIL Scale A score of 24 or higher on the Mini-Mental State Examination (MMSE) Provided written informed consent after being informed about the study\n\nExclusion Criteria:\n\nPresence of unstable cardiovascular disease Having received physical therapy and rehabilitation within the past 6 months History of severe neurological disorders History of major surgery affecting mobility within the past 6-12 months Severe musculoskeletal or orthopedic conditions that limit or preventt independent mobility.\n\n\\-","60 Years",{"count":113,"type":23},40,[26],"Brief Summary\n\nThis clinical study aims to compare the effects of a conventional exercise program and a Pilates exercise program in prefrail and frail older adults. A total of 40 participants aged 60 years and older who are classified as prefrail or frail according to the FRAIL Scale will be included in the study.\n\nParticipants will be randomly assigned to either the conventional exercise group or the Pilates group. Both exercise programs will be conducted twice weekly for 6 weeks. The interventions will focus on stretching exercises, balance and perturbation training, and strength exercises targeting major muscle groups.\n\nPrimary outcomes will include changes in frailty status assessed before and after the intervention. Secondary outcomes will include functional mobility and balance assessed by the Timed Up and Go Test, dynamic balance assessed by the Functional Reach Test, lower extremity strength assessed by the 30-Second Sit-to-Stand Test, gait speed assessed by the 10-Meter Walk Test, depressive symptoms and psychological well-being assessed by the Yesavage Geriatric Depression Scale, independence in daily activities assessed by the Lawton Instrumental Activities of Daily Living Scale, cognitive status assessed by the Mini-Mental State Examination, and fatigue assessed by the Modified Borg Scale. Frailty status will be evaluated using the FRAIL Scale.\n\nThroughout the study, participant safety will be monitored, and any adverse events, such as injuries or discomfort occurring during exercise sessions, will be recorded and managed appropriately.\n\nThis study is expected to provide valuable clinical evidence regarding the effectiveness of conventional exercise and Pilates programs in improving physical health and reducing frailty in prefrail and frail older adults, thereby contributing to the identification of best practice approaches for the management of this vulnerable population.",[117,118,119,120],"Frailty Syndrome","Prefrail Elderly","Frail Elderly","Geriatric",[122,123,124,125,126,127],"Pilates","geriatric","conventional","frailty","exercises","prefrail","2026-06-20",{"date":130,"type":39},"2026-06-25",{"date":41,"type":23},{"date":133,"type":23},"2027-02",{"name":45,"class":46},{"id":136,"slug":137,"hasResults":12,"nctId":138,"briefTitle":139,"officialTitle":140,"acronym":141,"eligibilityCriteria":142,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":143,"targetDuration":4,"studyType":144,"phases":4,"briefSummary":145,"conditions":146,"keywords":150,"overallStatus":156,"whyStopped":4,"lastUpdateSubmitDate":157,"lastUpdatePostDateStruct":158,"startDateStruct":159,"completionDateStruct":161,"leadSponsor":162,"locationsCount":47},"100643944","multimodality-rv-phenotyping-for-risk-stratification-and-short-term-outcomes-in-group-1-pah-100643944","NCT07667673","Multimodality RV Phenotyping for Risk Stratification and Short-Term Outcomes in Group 1 PAH","Multimodality Imaging-Based Right Ventricular Phenotyping for Risk Stratification and Short-Term Outcomes in Group 1 Pulmonary Arterial Hypertension: The MIRROR-PAH Study","MIRROR-PAH","Inclusion Criteria:\n\n* Adults aged 18 years or older\n* Diagnosis of Group 1 pulmonary arterial hypertension (PAH) according to ESC\u002FERS guidelines\n* Followed at the study center with a diagnosis of PAH\n* Availability of right heart catheterization (RHC) and cardiac magnetic resonance (CMR) imaging data obtained within a clinically relevant time interval\n* Availability of analyzable clinical, imaging, and hemodynamic data\n* Willingness to participate in the study and provision of written informed consent\n\nExclusion Criteria:\n\n* Age younger than 18 years\n* Pulmonary hypertension groups other than Group 1 PAH (Groups 2-5 PH)\n* Absence of either right heart catheterization or cardiac magnetic resonance imaging data within a clinically relevant time interval\n* Incomplete clinical or imaging data preventing analysis\n* Unavailable follow-up data",{"count":22,"type":23},"OBSERVATIONAL","The MIRROR-PAH is a single-center, prospective, observational cohort study evaluating the incremental value of multimodality imaging-derived right ventricular characteristics for risk stratification in patients with Group 1 pulmonary arterial hypertension (PAH). The study aims to determine whether incorporation of echocardiographic and cardiac magnetic resonance (CMR)-derived right ventricular parameters into established non-invasive risk assessment models results in risk reclassification and improves identification of patients at risk for short-term clinical worsening.\n\nAdult patients with established Group 1 PAH undergoing routine follow-up and with available right heart catheterization (RHC) and CMR data will be consecutively enrolled. Clinical, laboratory, echocardiographic, and follow-up data will be prospectively collected over a 6-month period. Associations between multimodality imaging findings, invasive hemodynamic measurements, risk classification, and short-term clinical outcomes will be evaluated.",[147,148,149],"Pulmonary Hypertension","Pulmonary Arterial Hypertension","Right Ventricular Function",[151,152,153,154,155],"pulmonary arterial hypertension","transthoracic echocardiography","cardiac magnetic resonance imaging","right heart catheterization","risk stratification","RECRUITING","2026-06-19",{"date":130,"type":39},{"date":160,"type":39},"2026-05-11",{"date":76,"type":23},{"name":45,"class":46},{"id":164,"slug":165,"hasResults":12,"nctId":166,"briefTitle":167,"officialTitle":168,"acronym":169,"eligibilityCriteria":170,"healthyVolunteers":12,"sex":18,"minAge":171,"maxAge":19,"enrollmentInfo":172,"targetDuration":4,"studyType":144,"phases":4,"briefSummary":174,"conditions":175,"keywords":181,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":183,"lastUpdatePostDateStruct":184,"startDateStruct":186,"completionDateStruct":188,"leadSponsor":190,"locationsCount":47},"100642191","core-stability-functional-capacity-balance-strength-and-fatigue-in-pediatric-demyelinating-diseases-100642191","NCT07654738","Core Stability, Functional Capacity, Balance, Strength, and Fatigue in Pediatric Demyelinating Diseases","Investigation of the Relationship Between Core Stability, Functional Capacity, Balance, Lower Extremity Strength, and Fatigue in Pediatric Demyelinating Diseases","PEDI-CORE","Inclusion Criteria:\n\n* Age between 6 and 18 years\n* Diagnosed with a pediatric demyelinating disease\n* No relapse within the last 3 months\n* No botulinum toxin (Botox) injections within the last 3 months\n* No corticosteroid treatment within the last 3 months\n* Ability to read and write\n\nExclusion Criteria:\n\n* History of concomitant autoimmune diseases\n* Refusal of the patient and\u002For caregiver to participate in the study\n* History of another primary neurological disease\n* Cognitive impairment that limits understanding of instructions and participation in assessments\n* Visual and\u002For hearing impairments that interfere with activities of daily living\n* Presence of additional rheumatological conditions that may interfere with assessments\n* Spasticity grade ≥2 according to the Modified Ashworth Scale in any muscle group","6 Years",{"count":173,"type":23},32,"This study aims to evaluate balance ability, core stability, functional capacity, lower extremity muscle strength, and fatigue levels in children diagnosed with central nervous system demyelinating diseases, in order to contribute to the development of evidence-based and individualized rehabilitation strategies.",[176,177,178,179,180],"Demyelinating Diseases of the Central Nervous System","Child","Core Stability","Balance","Fatigue",[182,178,179,180],"Pediatric Demyelinating Diseases","2026-06-12",{"date":185,"type":39},"2026-06-17",{"date":187,"type":23},"2026-07-30",{"date":189,"type":23},"2028-01-30",{"name":45,"class":46},{"id":192,"slug":193,"hasResults":12,"nctId":194,"briefTitle":195,"officialTitle":196,"acronym":197,"eligibilityCriteria":198,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":199,"enrollmentInfo":200,"targetDuration":202,"studyType":144,"phases":4,"briefSummary":203,"conditions":204,"keywords":210,"overallStatus":156,"whyStopped":4,"lastUpdateSubmitDate":183,"lastUpdatePostDateStruct":217,"startDateStruct":219,"completionDateStruct":221,"leadSponsor":223,"locationsCount":47},"100615091","target-controlled-infusion-tci-vs-inhalational-anesthesia-in-video-assisted-thoracoscopic-surgery-vats-100615091","NCT07288099","Target-Controlled Infusion (TCI) vs Inhalational Anesthesia in Video-Assisted Thoracoscopic Surgery (VATS)","Prospective Observational Cohort Study Comparing Recovery Profiles After Target-Controlled Infusion Versus Inhalational Anesthesia in Video-Assisted Thoracoscopic Surgery","TCI-INHALE","Inclusion Criteria:\n\n* Adults aged 18 to 65 years\n\nPatients scheduled for elective video-assisted thoracoscopic surgery (VATS)\n\nASA physical status I-III\n\nAble to provide informed consent\n\nPlanned postoperative recovery in PACU and surgical ward\n\nExclusion Criteria:\n\n* ASA IV or higher\n\nHemodynamic or respiratory instability before surgery\n\nKnown allergy or contraindication to commonly used anesthetic agents\n\nNeurological or psychiatric conditions that may interfere with recovery assessment\n\nEmergency surgeries\n\nPatients who decline participation","80 Years",{"count":201,"type":23},100,"1 Day","This study is designed as a prospective observational cohort to evaluate recovery after video-assisted thoracoscopic surgery (VATS). In our clinic, anesthesia for VATS is commonly provided either with target-controlled infusion (TCI) or with inhalational agents, depending on the routine practice of the anesthesiologist. No randomization or additional intervention will be performed.\n\nDuring the study period, patients who receive either method as part of standard care will be followed, and perioperative and postoperative data will be recorded. Awakening time, extubation time, Aldrete score progression, pain levels, and early postoperative complications will be compared between the two groups. The aim is to better understand how these widely used anesthesia techniques may influence recovery in VATS patients and to support future clinical decision-making.",[205,206,207,208,209],"Video-assisted Thoracoscopic Surgery (VATS)","Thoracic Surgery, Video Assisted","Postoperative Recovery","General Anesthesia","Anesthesia Techniques",[211,212,213,214,215,207,216],"Video-Assisted Thoracoscopic Surgery","VATS","Thoracic Surgery","Target-Controlled Infusion","Inhalational Anesthesia","Extubation Time",{"date":218,"type":39},"2026-06-15",{"date":220,"type":39},"2026-01-12",{"date":222,"type":23},"2026-07",{"name":45,"class":46},{"id":225,"slug":226,"hasResults":12,"nctId":227,"briefTitle":228,"officialTitle":229,"acronym":4,"eligibilityCriteria":230,"healthyVolunteers":12,"sex":231,"minAge":19,"maxAge":4,"enrollmentInfo":232,"targetDuration":4,"studyType":24,"phases":234,"briefSummary":235,"conditions":236,"keywords":4,"overallStatus":156,"whyStopped":4,"lastUpdateSubmitDate":242,"lastUpdatePostDateStruct":243,"startDateStruct":245,"completionDateStruct":247,"leadSponsor":249,"locationsCount":47},"100584757","virtual-reality-based-and-face-to-face-relaxation-programs-in-pregnant-women-with-preeclampsia-100584757","NCT06893510","Virtual Reality-Based and Face-to-Face Relaxation Programs in Pregnant Women With Preeclampsia","The Effect of Virtual Reality-Based and Face-to-Face Relaxation Programs on Maternal and Fetal Outcomes in Pregnant Women With Preeclampsia","Inclusion Criteria:\n\n* Hospitalized with a diagnosis of preeclampsia.\n* Gestational age ≥26 weeks.\n* 18 years or older.\n* Singleton and viable pregnancy.\n* Willing to participate in the study voluntarily.\n\nExclusion Criteria:\n\n* Multiple pregnancy.\n* Pregnancy achieved through assisted reproductive technologies.\n* Hearing or vision impairment in the pregnant individual.\n* Fetal distress requiring emergency intervention.\n* HELLP Syndrome or Eclampsia.\n* History of vertigo.\n\nWithdrawal Criteria:\n\n* Cases where live birth does not occur.\n* Participants who voluntarily withdraw from the study.\n* Participants whose general health condition deteriorates during the intervention.\n* Participants experiencing side effects from virtual reality headset use (e.g., dizziness, nausea, headache).\n* Participants who do not practice progressive muscle relaxation at least once a week after the intervention.","FEMALE",{"count":233,"type":23},96,[26],"Preeclampsia, affecting 2-8% of pregnancies globally, is a leading hypertensive disorder in pregnancy. It is clinically characterized by elevated blood pressure (≥140\u002F90 mmHg) after the 20th gestational week, often accompanied by proteinuria and systemic complications such as thrombocytopenia, liver dysfunction, and cerebral symptoms. This condition poses significant risks for both maternal and fetal health, increasing the likelihood of organ damage, preterm birth, and long-term cardiovascular and neurodevelopmental complications. Non-pharmacological interventions, including relaxation techniques, have been explored for symptom management. Progressive muscle relaxation (PMR) has shown efficacy in reducing stress, anxiety, and blood pressure. Recently, virtual reality (VR)-based relaxation techniques have gained attention for enhancing stress relief and improving health outcomes. This study aims to compare the effects of VR-based PMR with in-person PMR on maternal and fetal outcomes in preeclamptic pregnancies.",[237,238,239,240,241],"Pre-Eclampsia","Maternal Health","Relaxation","Virtual Reality","Fetal Monitoring","2026-06-07",{"date":244,"type":39},"2026-06-10",{"date":246,"type":39},"2025-09-08",{"date":248,"type":23},"2026-09-01",{"name":45,"class":46},{"id":251,"slug":252,"hasResults":12,"nctId":253,"briefTitle":254,"officialTitle":255,"acronym":256,"eligibilityCriteria":257,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":199,"enrollmentInfo":258,"targetDuration":4,"studyType":144,"phases":4,"briefSummary":260,"conditions":261,"keywords":265,"overallStatus":156,"whyStopped":4,"lastUpdateSubmitDate":267,"lastUpdatePostDateStruct":268,"startDateStruct":270,"completionDateStruct":272,"leadSponsor":274,"locationsCount":47},"100643494","assessment-of-renal-perfusion-using-ultrasound-and-near-infrared-spectroscopy-in-patients-undergoing-minimally-invasive-abdominal-surgery-100643494","NCT07635160","Assessment of Renal Perfusion Using Ultrasound and Near-Infrared Spectroscopy in Patients Undergoing Minimally Invasive Abdominal Surgery","Prospective Observational Evaluation of Renal Perfusion Using Doppler Ultrasonography and Near-Infrared Spectroscopy in Patients Undergoing Elective Minimally Invasive Abdominal Surgery","RRI-NIRS","Inclusion Criteria:\n\n* Patients aged 18 to 80 years\n* Patients with ASA physical status I, II, or III\n* Patients undergoing elective minimally invasive abdominal surgery for any reason\n* Patients whose expected surgical duration is longer than 1 hour\n\nExclusion Criteria:\n\n* Body mass index greater than 35 kg\u002Fm²\n* Severe respiratory system disease\n* Severe heart failure, NYHA class III-IV\n* Presence of a cardiac pacemaker or cardiac defibrillator implant\n* Progressive neuromuscular disease\n* High intra-abdominal pressure\n* Sudden deterioration of general condition\n* Incomplete clinical or laboratory data\n* Refusal to participate in the study\n* Conversion to open surgery",{"count":259,"type":23},51,"This prospective observational study aims to evaluate renal perfusion in adult patients undergoing elective minimally invasive abdominal surgery. Renal perfusion will be assessed using two non-invasive monitoring techniques: Doppler ultrasonography-derived Renal Resistive Index (RRI) and Near-Infrared Spectroscopy (NIRS)-derived renal regional oxygen saturation (rSO₂).\n\nMeasurements will be obtained at predefined perioperative time points, including after induction of anesthesia, during pneumoperitoneum, before extubation, and during the early postoperative period. Perioperative changes in renal perfusion parameters will be analyzed and correlated with clinical variables such as intra-abdominal pressure, pneumoperitoneum duration, hemodynamic parameters, fluid administration, urine output, and postoperative renal function.\n\nThe study also aims to investigate the relationship between intraoperative renal perfusion changes and the development of postoperative acute kidney injury. The findings may contribute to improved perioperative monitoring and optimization of renal perfusion during minimally invasive abdominal surgery.",[262,263,264],"Renal Perfusion","Minimally Invasive Surgical Procedures","Acute Kidney Injury",[266],"Kidney Perfusion,Renal Resistive Index,Near-Infrared Spectroscopy,Acute Kidney Injury,Laparoscopic Surgery","2026-06-03",{"date":269,"type":39},"2026-06-09",{"date":271,"type":39},"2026-01-07",{"date":273,"type":23},"2027-01-07",{"name":45,"class":46},{"id":276,"slug":277,"hasResults":12,"nctId":278,"briefTitle":279,"officialTitle":280,"acronym":4,"eligibilityCriteria":281,"healthyVolunteers":12,"sex":18,"minAge":20,"maxAge":85,"enrollmentInfo":282,"targetDuration":4,"studyType":24,"phases":284,"briefSummary":285,"conditions":286,"keywords":292,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":267,"lastUpdatePostDateStruct":297,"startDateStruct":299,"completionDateStruct":300,"leadSponsor":302,"locationsCount":47},"100642932","exercise-interventions-in-obstructive-sleep-apnea-syndrome-100642932","NCT07634029","Exercise Interventions in Obstructive Sleep Apnea Syndrome","The Effect of Exercise Snacks and Aerobic Exercise on Circadian Rhythm and Functional Capacity in Individuals With Obstructive Sleep Apnea Syndrome","Inclusion Criteria:\n\n* Individuals diagnosed with OSAHS (AHI ≥ 15) confirmed by polysomnography, with moderate or severe disease, who have been receiving CPAP therapy for at least 3 months.\n* Adults aged 30-65 years.\n* No participation in any regular exercise program within the last 6 months.\n\nExclusion Criteria:\n\n* Individuals with OSAHS and a body mass index (BMI) \\> 35 kg\u002Fm²\n* Severe chronic pulmonary disease\n* Neurological or musculoskeletal disorders that prevent exercise\n* Unstable cardiovascular conditions\n* Unstable metabolic conditions\n* Severe psychiatric disorders such as bipolar disorder or schizophrenia\n* Pregnancy or breastfeeding\n* Individuals working night shifts or with schedules that may cause jet lag\n* Use of steroid or hormone therapy\n* Use of melatonin or sleep-regulating medications within the last 3 months\n* Presence of acute infection or inflammation",{"count":283,"type":23},39,[26],"Obstructive Sleep Apnea Syndrome (OSA) is a condition characterized by repeated pauses or reductions in breathing during sleep, which can negatively affect sleep quality, daytime functioning, and physical capacity. Although regular exercise is known to have beneficial effects in OSA, the effects of different exercise approaches on circadian rhythm and functional capacity have not been sufficiently investigated.The primary aim of this study is to compare the effects of exercise snacking and aerobic exercise on circadian rhythm and functional capacity in individuals with OSA, in comparison with a control group. The secondary aim is to evaluate the effects of these exercise interventions on peripheral muscle strength, fatigue level, body composition, quality of life, and physical activity level.Participants will be randomly assigned to three groups: an aerobic exercise group, an exercise snacking group, and a control group. While the exercise groups will follow their respective intervention programs, the control group will continue their routine treatment.This study aims to answer whether exercise snacking, which consists of short bouts of exercise distributed throughout the day, may be an alternative or complementary approach to traditional aerobic exercise in individuals with OSA. In addition, this study aims to be the first randomized controlled trial evaluating the effects of exercise snacking on circadian rhythm and functional capacity in individuals with OSA.",[287,288,289,290,291],"Obstructive Sleep Apnea (OSA)","Exercise Snacks","Physical Activity","Circadian Rhythm","Sleep",[293,294,295,296],"Obstructive Sleep Apnea","exercise training","circadian rhythm","exercise snacks",{"date":298,"type":39},"2026-06-08",{"date":248,"type":23},{"date":301,"type":23},"2028-02",{"name":45,"class":46},{"id":304,"slug":305,"hasResults":12,"nctId":306,"briefTitle":307,"officialTitle":308,"acronym":4,"eligibilityCriteria":309,"healthyVolunteers":17,"sex":18,"minAge":310,"maxAge":311,"enrollmentInfo":312,"targetDuration":4,"studyType":144,"phases":4,"briefSummary":314,"conditions":315,"keywords":318,"overallStatus":156,"whyStopped":4,"lastUpdateSubmitDate":323,"lastUpdatePostDateStruct":324,"startDateStruct":326,"completionDateStruct":328,"leadSponsor":330,"locationsCount":47},"100582955","dynamic-gait-index-as-a-functional-gait-assessment-measure-in-children-with-jia-100582955","NCT06870045","Dynamic Gait Index as a Functional Gait Assessment Measure in Children With JIA","Investigation of Validity and Reliability of Dynamic Walking Index in Childhood Rheumatic Diseases","Inclusion Criteria:\n\n* Study Group;\n* Having a JIA diagnosis according to ILAR criteria between the ages of 8-16,\n* Having unilateral knee joint involvement that will affect walking\n* Being compatible, volunteer and cooperative in the study Control Group;\n\n  1. Not having any neurological or orthopedic diagnosis\n  2. Being between the ages of 8-16\n  3. Being at a mental level that can understand the commands of the person performing the evaluation\n\nExclusion Criteria:\n\n* Study Group;\n* Having an additional neurological or orthopedic diagnosis accompanying JIA and affecting treatment results,\n* Having lower extremity asymmetry or active lower extremity involvement other than the knee joint that will affect walking.\n\nControl Group;\n\n-Having any health problem that may affect the study","8 Years","16 Years",{"count":313,"type":23},52,"Juvenile idiopathic arthritis (JIA) is one of the most common chronic rheumatic diseases seen in childhood. Pain, joint swelling and loss of function caused by inflammation significantly reduce the patients' quality of life and lead to muscle weakness, limited range of motion and gait disorders. Although there are various clinical assessment methods, there is no functional test in the current literature that evaluates walking in children with JIA.\n\nThe Dynamic Gait Index (DGI) is a functional walking scale that evaluates walking on level ground, walking while changing speed, walking with sideways head turns, walking with vertical head turns, walking with pivot turns, walking by jumping over obstacles, going around obstacles and climbing stairs. While the DGA is widely used in the clinical assessment of walking in older adults and other pediatric patient groups, it has not yet been investigated for the assessment of walking difficulties in children with JIA. This study aimed to determine whether the DYI is a usable tool for assessing walking in children with JIA.",[316,317],"Juvenile Idiopathic Arthritis","Childhood Rheumatic Disease",[319,320,321,322],"juvenile idiopathic arthritis","gait","dynamic gait index","childhood rheumatic diseases","2026-06-01",{"date":325,"type":39},"2026-06-02",{"date":327,"type":39},"2025-02-01",{"date":329,"type":23},"2026-10",{"name":45,"class":46},{"id":332,"slug":333,"hasResults":12,"nctId":334,"briefTitle":335,"officialTitle":336,"acronym":4,"eligibilityCriteria":337,"healthyVolunteers":12,"sex":18,"minAge":338,"maxAge":19,"enrollmentInfo":339,"targetDuration":340,"studyType":144,"phases":4,"briefSummary":341,"conditions":342,"keywords":344,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":348,"lastUpdatePostDateStruct":349,"startDateStruct":350,"completionDateStruct":352,"leadSponsor":354,"locationsCount":4},"100640752","validity-and-reliability-of-the-international-physical-fitness-questionnaire-and-the-self-perceived-health-related-physical-fitness-questionnaire-in-children-and-adolescents-with-jia-and-fmf-100640752","NCT07617558","Validity and Reliability of the International Physical Fitness Questionnaire and the Self-Perceived Health-Related Physical Fitness Questionnaire in Children and Adolescents With JIA and FMF","Investigation of the Validity and Reliability of the International Physical Fitness Questionnaire and the Self-Perceived Health-Related Physical Fitness Questionnaire for Children in Children and Adolescents Diagnosed With Juvenile Idiopathic Arthritis and Familial Mediterranean Fever","Inclusion Criteria:\n\n* Age between 10 and 18 years\n* Diagnosis of Familial Mediterranean Fever (FMF) or Juvenile Idiopathic Arthritis (JIA) established by a pediatric rheumatologist at least six months prior\n* Voluntary willingness to participate in the study\n* Provision of informed consent by both the participant and their parents\u002Fguardians\n* Ability to ambulate independently, communicate effectively, and comply with the instructions required for the research assessments\n* Sufficient literacy to comprehend written instructions and complete study-related materials\n\nExclusion Criteria:\n\n* Having a history of a mental or psychological problem that would prevent the understanding of questions or compliance with given instructions.\n* Medically unstable conditions (history of hospitalization due to heart or lung disease or a disease flare within the 4 weeks prior to the test).\n* Having a history of a chronic disease of cardiovascular, orthopedic, neuromuscular, or neurological origin that could affect physical fitness.\n* Having a history of trauma affecting the musculoskeletal system within the last 6 months.","10 Years",{"count":201,"type":23},"7 Days","Juvenile Idiopathic Arthritis (JIA) and Familial Mediterranean Fever (FMF), two of the most prevalent pediatric rheumatologic diseases, significantly compromise the physical health of children and adolescents, leading to reduced physical fitness, muscle weakness, and a sedentary lifestyle. This study aims to evaluate the validity and reliability of the International Fitness Scale (IFS) and the Self-Perceived Health-Related Fitness Questionnaire for Children (PHFQ-C) as assessment tools for physical fitness in individuals diagnosed with JIA and FMF. Our hypothesis is that these scales will provide demonstrably reliable and valid data within this patient population. To test this, 98 patients aged 10-18 years, recruited from the Pediatric Rheumatology Clinic at Istanbul Faculty of Medicine, will participate. Their physical fitness will be objectively measured using the FitnessGram Test Battery (assessing aerobic capacity, muscular strength, and flexibility), while the IFS and PHFQ-C will be administered online. Statistical analysis, conducted using SPSS 25.0, will employ Pearson\u002FSpearman correlation for validity and Cronbach's alpha and test-retest Intraclass Correlation Coefficient (ICC) for reliability.\n\nThe expected findings will confirm the utility of the IFS and PHFQ-C as practical, economical, and valid instruments for assessing physical fitness in children and adolescents with JIA\u002FFMF. Promoting the widespread use of these scales in clinical settings will facilitate the rapid and convenient evaluation of patients' fitness levels, thereby enabling the development of early, targeted intervention strategies and ultimately contributing to an improved quality of life. Furthermore, by offering a validated alternative to standard test batteries-which are often cumbersome due to requirements for time, specialized equipment, and expert personnel-this work will make a valuable methodological contribution to the existing scientific literature.",[316,343],"Familial Mediterranean Fever",[316,343,345,346,347],"physical fitness","reliability","validity","2026-05-29",{"date":323,"type":39},{"date":351,"type":23},"2026-07-01",{"date":353,"type":23},"2026-10-30",{"name":45,"class":46},{"id":356,"slug":357,"hasResults":12,"nctId":358,"briefTitle":359,"officialTitle":360,"acronym":361,"eligibilityCriteria":362,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":363,"targetDuration":4,"studyType":24,"phases":365,"briefSummary":366,"conditions":367,"keywords":369,"overallStatus":156,"whyStopped":4,"lastUpdateSubmitDate":348,"lastUpdatePostDateStruct":373,"startDateStruct":374,"completionDateStruct":376,"leadSponsor":378,"locationsCount":47},"100639775","the-effect-of-education-brain-tumors-100639775","NCT07617168","The Effect of Education Brain Tumors","The Effect of the Education for Brain Tumor Patients and Their Caregivers on the Quality of Life and Care Burden","Education&BT","Inclusion Criteria\n\nFor Patients\n\n* Aged \\>18 years\n* Undergoing primary brain tumor surgery for the first time\n* Glasgow Coma Scale score of 15\n* Able to assess and express symptoms\n* Literate in Turkish\n* No psychiatric history\n* Not using psychiatric medication\n* Willing to participate and provide consent\n\nFor Caregivers\n\n* Aged \\>18 years\n* Primary caregiver providing care for at least 3 months\n* Open to communication and cooperation\n* No psychiatric history\n* Not using psychiatric medication\n* Willing to participate and provide consent\n\nExclusion Criteria\n\n* Not meeting the inclusion criteria\n* Intubated patients\n* Patients with metastatic brain tumors\n* Patients with pituitary tumors",{"count":364,"type":23},72,[26],"This study was designed to evaluate the impact of education programs for patients with primary brain tumors and their caregivers on quality of life and the burden of care experienced by caregivers.",[368],"Primary Brain Neoplasms",[370,371,372],"primary brain tumors","structed education","patients caregiver",{"date":325,"type":39},{"date":375,"type":39},"2026-03-25",{"date":377,"type":23},"2027-12-31",{"name":45,"class":46},{"id":380,"slug":381,"hasResults":12,"nctId":382,"briefTitle":383,"officialTitle":384,"acronym":4,"eligibilityCriteria":385,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":386,"enrollmentInfo":387,"targetDuration":4,"studyType":24,"phases":388,"briefSummary":389,"conditions":390,"keywords":393,"overallStatus":156,"whyStopped":4,"lastUpdateSubmitDate":401,"lastUpdatePostDateStruct":402,"startDateStruct":404,"completionDateStruct":406,"leadSponsor":408,"locationsCount":47},"100637525","mobilization-techniques-for-nonspecific-neck-pain-effects-on-cervical-endurance-and-function-100637525","NCT07605013","Mobilization Techniques for Nonspecific Neck Pain: Effects on Cervical Endurance and Function","Comparison of Different Mobilization Techniques on Cervical Muscle Endurance and Functional Performance in Patients With Nonspecific Neck Pain","Inclusion Criteria:\n\n* Healthy individuals aged 18-40 years\n* Individuals working at a desk job (office or remote) for at least 6 hours per day\n* Physically active individuals with no neck pain (NPRS score 0-2)\n* Voluntary consent to participate in the study\n\nExclusion Criteria:\n\n* History of neck trauma, surgery, or any cardiovascular, metabolic, neurological, or rheumatoid arthritis condition within the last 6 months\n* Participation in a manual therapy or physiotherapy program within the last 6 months\n* Presence of severe malignancy, rheumatoid arthritis, or cardiovascular disease\n* Pregnancy or breastfeeding","40 Years",{"count":259,"type":23},[26],"This clinical study investigates the comparative effects of two manual therapy mobilization techniques, Positional Release Technique (PRT) and Instrument-Assisted Soft Tissue Mobilization (İASTM), on cervical muscle endurance and functional performance in individuals with nonspecific neck pain. Nonspecific neck pain is a common musculoskeletal condition among office workers and students, often associated with poor posture, prolonged sitting, and repetitive strain. It leads to reduced muscle endurance, impaired functional capacity, and decreased quality of life. Early and effective management strategies are essential to prevent chronicity and disability.\n\nA total of 51 participants will be recruited and randomly assigned into three groups: Group 1 will receive PRT combined with a standardized home exercise program, Group 2 will receive İASTM combined with the same home exercise program, and Group 3 will serve as the control group receiving only conventional home exercise. The interventions will be delivered over a period of 4 weeks, with three sessions per week, under the supervision of trained physiotherapists. The home exercise program includes stretching, strengthening, and posture correction exercises designed to support cervical spine health.\n\nThe primary outcomes of the study are cervical muscle endurance and functional performance, measured using validated clinical tests. Secondary outcomes include pain intensity assessed by the Visual Analog Scale (VAS), functional disability measured by the Neck Disability Index (NDI), health-related quality of life assessed by the SF-12 questionnaire, and work-related performance indicators. Assessments will be conducted at baseline and after 4 weeks of intervention. Randomization and blinding procedures will be applied to minimize bias, and standardized protocols will ensure consistency across groups.\n\nThe main objective of this study is to determine whether the early application of PRT or İASTM, in combination with home exercise, provides superior improvements in cervical muscle endurance, pain reduction, and functional outcomes compared to exercise alone. By comparing these two mobilization techniques, the study aims to contribute evidence-based knowledge to physiotherapy practice and guide clinicians in selecting effective manual therapy approaches for nonspecific neck pain. The findings are expected to support clinical decision-making, improve patient care, and enhance rehabilitation strategies for individuals suffering from neck pain in occupational and daily life contexts.",[391,392],"Neck Pain Musculoskeletal","Nonspecific Neck Pain",[392,394,395,396,397,398,399,400],"Manual Therapy","Positional Release Technique","Instrument-Assisted Soft Tissue Mobilization","Cervical Muscle Endurance","Physiotherapy","Randomized Controlled Trial","Office Workers","2026-05-25",{"date":403,"type":39},"2026-05-28",{"date":405,"type":39},"2026-03-16",{"date":407,"type":23},"2027-01-16",{"name":45,"class":46},{"id":410,"slug":411,"hasResults":12,"nctId":412,"briefTitle":413,"officialTitle":414,"acronym":4,"eligibilityCriteria":415,"healthyVolunteers":12,"sex":231,"minAge":19,"maxAge":386,"enrollmentInfo":416,"targetDuration":4,"studyType":24,"phases":417,"briefSummary":418,"conditions":419,"keywords":4,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":424,"lastUpdatePostDateStruct":425,"startDateStruct":427,"completionDateStruct":429,"leadSponsor":431,"locationsCount":47},"100621394","effect-of-topical-oxygen-and-led-light-therapy-on-nipple-crack-100621394","NCT07370051","Effect of Topical Oxygen and LED Light Therapy on Nipple Crack","Effect of Topical Oxygen and LED Light Therapy on Nipple Crack: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Individuals aged 18-40,\n* Those who gave birth at term (37-42 weeks),\n* Those whose baby was 0-28 days old at the first visit,\n* Those diagnosed with nipple fissures,\n* Breastfeeding their baby,\n* Those who have had a single birth,\n* Those without a diagnosis of psychiatric illness and who are not taking related medication.\n\nExclusion Criteria:\n\n* Those with infection, mastitis, abscess, etc. accompanying nipple injury,\n* Those who have started medical treatment for nipple injury,\n* Those who are unable to continue breastfeeding,\n* Those who feed their baby by expressing breast milk,\n* Those who show any adverse reaction to photosensitivity or exposure to sunlight.",{"count":259,"type":23},[26],"The World Health Organization and UNICEF define the protection and support of breastfeeding as one of the key determinants of maternal and newborn health. Nipple cracks are common in the postpartum period and cause breastfeeding problems. If not addressed early, they can lead to interrupted or complete cessation of breastfeeding. It is important to develop methods for effective, safe, and mother-friendly care of nipple cracks. Various care approaches, such as lanolin, natural products, and hydrogels, have been described in the literature. However, evidence for non-invasive agents that support wound healing at the cellular level is limited. Evidence for LED light application is limited, and there is no evidence regarding the effect of topical oxygen application on nipple cracks.\n\nThis project is designed as a randomized controlled trial to investigate the effect of topical oxygen and LED light therapy applied to nipple cracks on wound healing, pain, and breastfeeding success. The study will be conducted at the Lactation Unit of Istanbul Haseki Training and Research Hospital, Ministry of Health, between March and December 2026. The sample size was calculated using the G\\*Power program; with an effect size of 0.20, a significance level of 5%, and a power of 80%, a total of 51 mothers will be included in the study. Participants will be divided into three groups using the block randomization method: Topical Oxygen (n=17), LED Light Therapy (n=17), and Control (n=17). Standard breastfeeding counseling will be provided to all groups. In addition to the intervention groups, topical oxygen will be applied at a flow rate of 10 liters per minute for 20 minutes; LED light therapy will be applied at 630 nm red and 850 nm infrared wavelengths, at an energy dose of 15.3 J\u002Fcm², for 5 minutes. Interventions will be performed on days 0, 3, and 7. Data will be collected using a personal information form, wound size measurement, Nipple Trauma Score, Visual Analog Scale, and LATCH score. The validity and reliability of the Nipple Trauma Score in Turkish will be assessed within the scope of the project.\n\nTo reduce measurement and analysis bias, support will be obtained from an independent observer and a statistician.",[420,421,422,423],"Breastfeeding","Newborn Infant","Midwifery","Breast","2026-05-23",{"date":426,"type":39},"2026-05-27",{"date":428,"type":23},"2026-09-15",{"date":430,"type":23},"2027-04-15",{"name":45,"class":46},{"id":433,"slug":434,"hasResults":12,"nctId":435,"briefTitle":436,"officialTitle":437,"acronym":4,"eligibilityCriteria":438,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":439,"targetDuration":4,"studyType":144,"phases":4,"briefSummary":441,"conditions":442,"keywords":445,"overallStatus":156,"whyStopped":4,"lastUpdateSubmitDate":451,"lastUpdatePostDateStruct":452,"startDateStruct":454,"completionDateStruct":456,"leadSponsor":458,"locationsCount":47},"100639659","minimally-invasive-hemodynamic-monitoring-in-cardiac-ablation-100639659","NCT07603765","Minimally Invasive Hemodynamic Monitoring in Cardiac Ablation","Prospective Clinical Study of Minimally Invasive Hemodynamic Monitoring Outcomes in Cardiac Ablation Procedures","Inclusion Criteria:\n\n* Age ≥18 years\n* Patients scheduled for cardiac catheter ablation in the electrophysiology laboratory\n* Indication for ablation confirmed by a cardiologist\n* Ability to provide written informed consent\n* Planned invasive arterial blood pressure monitoring during the procedure\n\nExclusion Criteria:\n\n* Refusal or inability to provide informed consent\n* Failure to identify arrhythmogenic focus leading to cancellation of ablation procedure\n* Severe hemodynamic instability prior to procedure\n* Contraindication to invasive arterial catheterization\n* Incomplete hemodynamic data acquisition\n* Pregnancy",{"count":440,"type":23},27,"This prospective observational clinical study aims to evaluate the clinical utility of Pressure Recording Analytical Method (PRAM)-based minimally invasive hemodynamic monitoring in patients undergoing cardiac ablation procedures. The study will be conducted in the cardiac catheterization laboratory of Istanbul University-Cerrahpaşa Cardiology Institute and will include 27 adult patients scheduled for catheter ablation. Written informed consent will be obtained from all participants, and the study will adhere to the principles of the Declaration of Helsinki.",[443,444],"Cardiac Arrythmias","Anesthesia",[446,447,448,449,450],"catheter ablation","anesthesiology","conscious Sedation","deep sedation","hemodynamic monitoring","2026-05-21",{"date":453,"type":39},"2026-05-22",{"date":455,"type":39},"2026-04-30",{"date":457,"type":23},"2026-12-15",{"name":45,"class":46},{"id":460,"slug":461,"hasResults":12,"nctId":462,"briefTitle":463,"officialTitle":464,"acronym":465,"eligibilityCriteria":466,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":85,"enrollmentInfo":467,"targetDuration":4,"studyType":24,"phases":469,"briefSummary":470,"conditions":471,"keywords":474,"overallStatus":156,"whyStopped":4,"lastUpdateSubmitDate":451,"lastUpdatePostDateStruct":490,"startDateStruct":491,"completionDateStruct":493,"leadSponsor":495,"locationsCount":47},"100637249","accelerated-itbs-for-major-depression-100637249","NCT07603804","Accelerated iTBS for Major Depression","Investigation of the Relationship Between Changes in Neurobiological Biomarkers After Accelerated Transcranial Magnetic Stimulation Treatment and Treatment Response in Patients With Major Depressive Disorder","AIM-D","Inclusion Criteria:\n\n* Age between 18 and 65 years\n* Diagnosis of Major Depressive Disorder according to DSM-5 criteria\n* Inadequate response to at least one adequate antidepressant treatment trial\n* Hamilton Depression Rating Scale (HAM-D) score ≥14 at baseline\n* Stable dose of antidepressant medication for at least 4 weeks prior to study entry\n* Ability to provide written informed consent\n\nExclusion Criteria:\n\n* History of bipolar disorder, schizophrenia, schizoaffective disorder, or psychotic depression\n* Current substance use disorder\n* Neurological disorders that may affect brain function (e.g., epilepsy, multiple sclerosis, dementia, Parkinson's disease)\n* History of epileptic seizures\n* Severe head trauma\n* Presence of metal implants in the head or neck region\n* Cochlear implants\n* Cardiac pacemaker or implanted electronic devices\n* History of deep brain stimulation or vagus nerve stimulation\n* Previous neurosurgical procedures\n* Pregnancy or breastfeeding\n* Use of medications that may significantly affect neuroendocrine or inflammatory markers (e.g., corticosteroids, immunomodulators)\n* Endocrine disorders affecting the hypothalamic-pituitary-adrenal axis (e.g., Cushing's syndrome, Addison's disease, thyroid disorders)\n* Autoimmune diseases (e.g., systemic lupus erythematosus, rheumatoid arthritis, Hashimoto thyroiditis)\n* Recent surgery or acute infection\n* Active suicidal crisis, severe agitation, or inability to comply with study procedures",{"count":468,"type":23},35,[26],"Major depressive disorder (MDD) is a common and disabling psychiatric condition, and many patients do not achieve adequate response to standard antidepressant treatments. Accelerated intermittent theta burst stimulation (iTBS) is a promising neuromodulation approach that may provide rapid antidepressant effects. This prospective interventional study aims to evaluate the clinical effectiveness of accelerated bilateral dorsomedial prefrontal cortex iTBS in patients with MDD and to investigate treatment-related changes in neurobiological biomarkers, including cortisol, ACTH, BDNF, IL-1β, IL-6, TNF-α, and CRP. Associations between biomarker changes and treatment response will also be examined.",[472,473],"Major Depressive Disorder (MDD)","Treatment Resistant Depression (TRD)",[475,476,477,478,479,480,481,482,483,484,485,486,487,488,489],"Major Depressive Disorder","Treatment Resistant Depression","Depression","Transcranial Magnetic Stimulation","TMS","Intermittent Theta Burst Stimulation","iTBS","Accelerated TMS","Accelerated iTBS","Dorsomedial Prefrontal Cortex","Biomarkers","Neuroinflammation","BDNF","Cortisol","ACTH",{"date":453,"type":39},{"date":492,"type":39},"2026-03-08",{"date":494,"type":23},"2026-12-31",{"name":45,"class":46},{"id":497,"slug":498,"hasResults":12,"nctId":499,"briefTitle":500,"officialTitle":501,"acronym":4,"eligibilityCriteria":502,"healthyVolunteers":12,"sex":18,"minAge":171,"maxAge":311,"enrollmentInfo":503,"targetDuration":4,"studyType":24,"phases":505,"briefSummary":506,"conditions":507,"keywords":509,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":514,"lastUpdatePostDateStruct":515,"startDateStruct":516,"completionDateStruct":518,"leadSponsor":519,"locationsCount":4},"100639635","soft-tissue-release-for-elbow-pronation-in-cerebral-palsy-100639635","NCT07601165","Soft Tissue Release for Elbow Pronation in Cerebral Palsy","Distal Soft Tissue Release for Elbow Pronation Deformity in Cerebral Palsy: Functional Outcomes","Inclusion Criteria:\n\n* Being between 6 and 16 years of age,\n* Having a diagnosis of spastic-type cerebral palsy,\n* presenting with an elbow pronation deformity requiring surgical intervention,\n* obtaining consent from the parent\u002Fguardian\n\nExclusion Criteria:\n\n* History of previous upper-extremity surgery\n* History of progressive neurological disease\n* Cognitive or physical capacity insufficient to complete the assessment tools",{"count":504,"type":23},28,[26],"Upper extremity deformities are highly common in individuals with cerebral palsy (CP) as a result of motor control impairment and muscle imbalance. Among these deformities, elbow pronation deformities are frequently observed, particularly in spastic-type CP (Koman et al., 2004). The imbalance between the pronator muscle group (pronator teres, pronator quadratus) and the supinator muscle group (supinator, biceps brachii) leads to the forearm remaining in a persistent pronated position (Sahoo et al., 2017). This deformity is not only aesthetically concerning but also results in significant functional limitations. Both fine and gross motor skills-such as washing the face, handshaking, and clapping-are adversely affected (Soutar \\& McComas, 1990). Additionally, children may experience difficulty using assistive devices such as walkers, which in turn can negatively impact ambulation (Flett, 2003).\n\nAn elbow fixed in pronation forces children to compensate for limited range of motion by using shoulder and trunk movements, which over time predisposes them to abnormal postural development (Gracies, 2005). In advanced cases, structural alterations such as posterolateral radial head dislocations may also occur (Van Heest \\& House, 2000). Both conservative (orthoses, botulinum toxin injections, physical therapy) and surgical interventions are employed in the treatment of pronation deformities. Surgical options include tenotomy of the pronator teres and pronator quadratus, muscle transfers, or combined procedures (Zancolli, 1975). However, there is no consensus in the literature regarding which surgical method should be applied to which patient group and at what stage (House et al., 1981).\n\nThe aim of this study is to evaluate the effects of distal soft-tissue release surgery for the treatment of elbow pronation deformity on upper extremity function in children with cerebral palsy.",[508],"Cerebral Palsy",[510,511,512,513],"cerebral palsy","upper extremity","function","release surgery","2026-05-20",{"date":453,"type":39},{"date":517,"type":23},"2026-06-30",{"date":189,"type":23},{"name":45,"class":46},{"id":521,"slug":522,"hasResults":12,"nctId":523,"briefTitle":524,"officialTitle":525,"acronym":4,"eligibilityCriteria":526,"healthyVolunteers":17,"sex":18,"minAge":85,"maxAge":4,"enrollmentInfo":527,"targetDuration":528,"studyType":144,"phases":4,"briefSummary":529,"conditions":530,"keywords":533,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":538,"lastUpdatePostDateStruct":539,"startDateStruct":541,"completionDateStruct":543,"leadSponsor":545,"locationsCount":47},"100640366","validity-and-reliability-of-the-turkish-form-of-the-enjoyment-of-physical-activity-scale-8-in-geriatrics-with-minimal-cognitive-impairment-100640366","NCT07588685","Validity and Reliability of the Turkish Form of the Enjoyment of Physical Activity Scale-8 in Geriatrics With Minimal Cognitive Impairment","Validity and Reliability of the Turkish Form of the Enjoyment of Physical Activity Scale-8 (PACES-8) in Geriatric Individuals With Minimal Cognitive Impairment","Inclusion Criteria:\n\n* Being 65 years of age or older,\n* Having a diagnosis of Minimal Cognitive Impairment (MCI),\n* Having a Standardized Mini Mental Test (SMMT) score between 24 and 27 (mild cognitive impairment level),\n* Being largely independent in daily living activities (absence of functional dependency),\n* Being able to mobilize independently,\n* Having the communication level to understand and answer the survey questions,\n* Volunteering to participate in the study and providing written informed consent.\n\nExclusion Criteria:\n\n* Diagnosis of dementia or advanced cognitive impairment,\n* Acute medical conditions that prevent participation in physical activity,\n* Severe vision or hearing loss,\n* Presence of neurological or psychiatric disorders that prevent completion of questionnaire forms,\n* Serious neurological event within the last 6 months (stroke, traumatic brain injury, etc.).",{"count":201,"type":23},"1 Week","The main objective of this study is to examine the validity and reliability of the Turkish form of the Enjoyment of Physical Activity Scale-8 (PACES-8) in individuals aged 65 and over with Minimal Cognitive Impairment (MCI).",[120,531,532],"Elderly","Cognitive Abnormality",[534,535,536,537],"physical activity","enjoyment","cognitive impairment","elderly","2026-05-14",{"date":540,"type":39},"2026-05-18",{"date":542,"type":23},"2026-05-15",{"date":544,"type":23},"2026-08-01",{"name":45,"class":46},{"id":547,"slug":548,"hasResults":12,"nctId":549,"briefTitle":550,"officialTitle":551,"acronym":4,"eligibilityCriteria":552,"healthyVolunteers":12,"sex":18,"minAge":338,"maxAge":19,"enrollmentInfo":553,"targetDuration":4,"studyType":24,"phases":555,"briefSummary":556,"conditions":557,"keywords":559,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":538,"lastUpdatePostDateStruct":570,"startDateStruct":571,"completionDateStruct":572,"leadSponsor":574,"locationsCount":47},"100640592","basic-body-awareness-therapy-bbat-and-corrective-exercise-for-adolescent-hyperkyphosis-100640592","NCT07598591","Basic Body Awareness Therapy (BBAT) and Corrective Exercise for Adolescent Hyperkyphosis","The Effects of Basic Body Awareness Therapy Added to a Corrective Exercise Program on Body Image, Self-Esteem, and Posture in Adolescents With Postural Hyperkyphosis","Inclusion Criteria:\n\n* Adolescents aged between 10 and 18 years.\n* Diagnosis of postural hyperkyphosis confirmed by a thoracic kyphosis angle of 40 degrees or greater.\n\nExclusion Criteria:\n\n* Diagnosis of congenital or rigid spinal deformities, such as Scheuermann's kyphosis.\n* History of major spinal surgery, severe spinal trauma, or significant orthopedic conditions.\n* Presence of diagnosed neurological or vestibular diseases that may affect balance or movement.\n* Use of spinal braces or other corrective orthotic devices during the study period.\n* Having received formal physiotherapy or a structured exercise program for posture within the last 6 months.",{"count":554,"type":23},60,[26],"This study is designed as a randomized controlled trial to evaluate the additional benefits of Basic Body Awareness Therapy (BBAT) when combined with a corrective exercise program for adolescents with postural hyperkyphosis. Postural hyperkyphosis, defined as a thoracic kyphosis angle of 40 degrees or greater, often leads to physical misalignments and psychosocial issues such as decreased self-esteem and poor body image during adolescence. Participants will be randomly assigned to either Group A (Experimental) or Group B (Control) using a stratified block randomization method. Both groups will participate in a 12-week intervention consisting of supervised Schroth corrective exercises performed twice weekly. Group A will additionally receive one session per week of BBAT, a physiotherapy method focusing on movement quality, mental awareness, and the integration of physical and mental self-awareness through lying, sitting, standing, and walking exercises. Group B will receive Autogenic Training, a systematic relaxation technique, as an active control. Assessments will be conducted at baseline and at the end of the 12-week program. The primary outcome measures include body awareness (Body Awareness Questionnaire), aesthetic perception of the spine (Kyphosis Specific Spinal Appearance Questionnaire), self-esteem (Rosenberg Self-Esteem Scale), and digital posture analysis (PostureScreen Mobile). Secondary outcomes involve clinical measurements of kyphosis (Flexicurve and Wall-Occiput Distance), dynamic and static balance (Y-Balance Test and Single-Leg Stance Test), thoracic joint position sense, health-related quality of life (SRS-30), and pain intensity (Numeric Pain Rating Scale). The study aims to provide a comprehensive understanding of how mindfulness and movement awareness can enhance traditional physical rehabilitation for spinal postural disorders.",[558],"Hyperkyphosis, Adolescent",[560,561,562,563,564,565,566,567,568,569],"Postural Hyperkyphosis","Basic Body Awareness Therapy","Corrective Exercise","Adolescent Posture","Body Image","Self-Esteem","Schroth Method","Mind-Body Intervention","Spinal Deformity","Exercise Therapy",{"date":514,"type":39},{"date":348,"type":23},{"date":573,"type":23},"2027-07-29",{"name":45,"class":46},{"id":576,"slug":577,"hasResults":12,"nctId":578,"briefTitle":579,"officialTitle":580,"acronym":4,"eligibilityCriteria":581,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":85,"enrollmentInfo":582,"targetDuration":4,"studyType":24,"phases":583,"briefSummary":584,"conditions":585,"keywords":587,"overallStatus":156,"whyStopped":4,"lastUpdateSubmitDate":538,"lastUpdatePostDateStruct":593,"startDateStruct":594,"completionDateStruct":596,"leadSponsor":597,"locationsCount":598},"100590487","effects-of-feldenkrais-approach-in-cases-with-forward-head-posture-100590487","NCT06968052","Effects of Feldenkrais Approach in Cases With Forward Head Posture","Effects of Exercise and Feldenkrais Approaches on Position Sense, Strength, Range of Motion and Posture in Cases With Forward Head Posture","Inclusion Criteria:\n\n* Being between 18-65 years of age\n* CVA (cervicovertebral angle) ≤50° (16,17)\n* Spending at least 4 hours of daily desk time 5 days a week\n\nExclusion Criteria:\n\n* Having temporomandibular dysfunction\n* Having any spinal deformity\n* Having cervical trauma or pain treatment within the last 6 months\n* Having previously participated in a corrective exercise program\n* History of neurological disorder\n* History of spinal or thoracic surgery\n* Having hearing impairment\n* Use of analgesics\u002Fmuscle relaxants",{"count":554,"type":23},[26],"It is thought that adding approaches that increase posture awareness to corrective exercise programs will contribute to the treatment. The aim of the study is to evaluate the effect of adding the Feldenkrais method to the corrective exercise program applied to individuals with forward head posture on cervical joint position sense, muscle strength, joint range of motion and posture parameters.",[586],"Forward Head Posture",[588,589,590,30,591,592],"Rehabilitation","Posture","Proprioception","Muscle Strength","Spine",{"date":540,"type":39},{"date":595,"type":39},"2025-05-25",{"date":36,"type":23},{"name":45,"class":46},2,{"id":600,"slug":601,"hasResults":12,"nctId":602,"briefTitle":603,"officialTitle":604,"acronym":605,"eligibilityCriteria":606,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":607,"targetDuration":4,"studyType":24,"phases":608,"briefSummary":609,"conditions":610,"keywords":614,"overallStatus":156,"whyStopped":4,"lastUpdateSubmitDate":620,"lastUpdatePostDateStruct":621,"startDateStruct":622,"completionDateStruct":624,"leadSponsor":626,"locationsCount":47},"100636694","bis-guided-sedation-versus-standard-clinical-sedation-during-elective-electrical-cardioversion-for-atrial-fibrillation-100636694","NCT07569016","BIS-Guided Sedation Versus Standard Clinical Sedation During Elective Electrical Cardioversion for Atrial Fibrillation","Bispectral Index-Guided Sedation Versus Standard Clinical Assessment-Guided Sedation During Elective Electrical Cardioversion for Atrial Fibrillation: A Prospective, Single-Center, Randomized Controlled, Assessor-Blinded Trial","BIS-ECV-RCT","Inclusion Criteria:\n\n* Age ≥18 years\n* Documented atrial fibrillation with indication for elective electrical cardioversion\n* American Society of Anesthesiologists (ASA) physical status class I, II, or III\n* Left ventricular ejection fraction ≥30% on echocardiography\n* Adequate anticoagulation: INR ≥2.0, OR ≥3 weeks of therapeutic anticoagulation, OR absence of left atrial thrombus confirmed by transesophageal echocardiography\n* Ability and willingness to provide written informed consent\n\nExclusion Criteria:\n\n* Known allergy or contraindication to propofol or fentanyl, or their excipients (soy, egg)\n* Hemodynamic instability (systolic blood pressure \\\u003C90 mmHg or symptomatic hypotension)\n* Decompensated heart failure (NYHA functional class IV)\n* Severe obstructive sleep apnea requiring CPAP or BiPAP therapy\n* Anticipated difficult airway (modified Mallampati classification class III or IV)\n* Baseline oxygen saturation \\\u003C94% or active chronic obstructive pulmonary disease\n* Severe hepatic impairment (transaminases \\>3× upper limit of normal) or severe renal impairment (eGFR \\\u003C30 mL\u002Fmin\u002F1.73m²)\n* Active psychiatric illness or cognitive impairment precluding questionnaire completion\n* Pregnancy or breastfeeding\n* Alcohol or substance use within the preceding 24 hours\n* Prior participation in this trial",{"count":554,"type":23},[26],"Electrical cardioversion (ECV) is a standard procedure used to restore normal heart rhythm in patients with atrial fibrillation (AF) by delivering a brief electrical shock to the heart. Because the procedure is painful and distressing, patients receive sedation - a controlled state of reduced consciousness - using short-acting intravenous medications. However, the optimal depth of sedation for ECV has not been well defined: too deep may cause breathing problems and low blood pressure, while too light may result in pain, awareness, or patient movement during the shock.\n\nBispectral index (BIS) monitoring is a non-invasive technology that continuously measures brain activity using an EEG sensor placed on the forehead, generating a numerical score from 0 (no brain activity) to 100 (fully awake). BIS scores between 61 and 80 correspond to moderate sedation, which preliminary observations suggest may be sufficient for ECV without the risks associated with deeper sedation.\n\nThis randomized controlled trial will compare two approaches to sedation monitoring during elective ECV for AF:\n\n* Group 1 (BIS Group): Sedation is guided by BIS monitoring, targeting a score of 61-80.\n* Group 2 (Control Group): Sedation is guided by standard clinical assessment (loss of response to verbal commands and eyelash reflex), with BIS recorded but not visible to the treating team.\n\nBoth groups will receive the same medications (propofol and fentanyl). The primary outcome is how quickly patients recover after the procedure, measured by the Modified Aldrete Score - a standard clinical recovery assessment tool. Secondary outcomes include patient and physician satisfaction, procedural pain, risk of awareness during the procedure, cardioversion success rate, hemodynamic stability, and complication rates.\n\nThe trial will enroll 60 adult patients at Istanbul University-Cerrahpasa Cardiology Institute. Findings are expected to provide evidence-based guidance for standardizing sedation protocols during ECV.",[611,612,613],"Atrial Fibrillation","Electric Countershock","Deep Sedation",[615,612,616,617,618,619],"atrial fibrillation","sedation","bispectral index","propofol","anesthesia recovery","2026-05-12",{"date":542,"type":39},{"date":623,"type":39},"2026-04-13",{"date":625,"type":23},"2026-07-15",{"name":45,"class":46},{"id":628,"slug":629,"hasResults":12,"nctId":630,"briefTitle":631,"officialTitle":632,"acronym":4,"eligibilityCriteria":633,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":85,"enrollmentInfo":634,"targetDuration":4,"studyType":24,"phases":635,"briefSummary":636,"conditions":637,"keywords":641,"overallStatus":156,"whyStopped":4,"lastUpdateSubmitDate":160,"lastUpdatePostDateStruct":645,"startDateStruct":646,"completionDateStruct":647,"leadSponsor":649,"locationsCount":47},"100636202","video-based-physiotherapy-education-and-social-participation-in-adults-with-hand-injuries-100636202","NCT07562620","Video-Based Physiotherapy Education and Social Participation in Adults With Hand Injuries","Determination of Factors Affecting Social Participation and Evaluation of the Effectiveness of Video-Based Physiotherapy Awareness Education in Adults With Hand Injuries.","Inclusion Criteria:\n\n* Adults between 18 and 65 years of age.\n* Patients requiring rehabilitation after fractures, tendon injuries, or carpal tunnel syndrome surgery in the hand region.\n* Patients who have started physical therapy sessions for the first time within the last 6 months with these diagnoses.\n* Individuals with sufficient cognitive ability to answer the questionnaires independently.\n\nExclusion Criteria:\n\n* Individuals with cognitive impairment or communication barriers (such as severe vision or hearing loss) that would prevent them from following the questionnaire and educational content.\n* Active healthcare workers.\n* Patients referred only for conservative treatment.",{"count":113,"type":23},[26],"The goal of this clinical trial is to determine the factors affecting social participation in adult patients with hand injuries and to evaluate the effectiveness of a video-based physiotherapy awareness education in this population.\n\nThe main questions it aims to answer are:\n\nDoes a short, video-based physiotherapy education increase the knowledge and awareness levels of patients with hand injuries?\n\nWhat are the primary factors (body functions and activity limitations) that restrict the social participation of these patients?\n\nParticipants will:\n\nComplete baseline assessments including a sociodemographic form, the Quick-DASH questionnaire, and custom participation and awareness forms.\n\nReceive a 10-15 minute video-supported education session from physiotherapists covering home strategies, exercises, and assistive devices.\n\nComplete the knowledge and awareness test again immediately after the education session to measure acute changes.",[638,639,640],"Hand Injuries","Hand Injuries and Disorders","Patient Education",[642,398,643,644,588],"Video-Based Education","Health Literacy","Social Participation",{"date":538,"type":39},{"date":455,"type":39},{"date":648,"type":23},"2027-04-30",{"name":45,"class":46},{"id":651,"slug":652,"hasResults":12,"nctId":653,"briefTitle":654,"officialTitle":654,"acronym":4,"eligibilityCriteria":655,"healthyVolunteers":17,"sex":18,"minAge":85,"maxAge":4,"enrollmentInfo":656,"targetDuration":528,"studyType":144,"phases":4,"briefSummary":658,"conditions":659,"keywords":660,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":664,"lastUpdatePostDateStruct":665,"startDateStruct":667,"completionDateStruct":669,"leadSponsor":670,"locationsCount":47},"100636222","validity-and-reliability-of-the-exercise-related-health-beliefs-attitude-scale-in-geriatric-individuals-100636222","NCT07562880","Validity and Reliability of the Exercise-Related Health Beliefs Attitude Scale in Geriatric Individuals","Inclusion Criteria:\n\n* Being 65 years of age or older,\n* Volunteering to participate in the research\n* Not having a disease that affects cognitive function\n* Being able to understand the questions asked by the researchers\n* Volunteering\n\nExclusion Criteria:\n\n* Severe vision\u002Fhearing loss,\n* Having cognitive diseases such as dementia, Alzheimer's, etc.\n* Inability to walk\n* Not being a volunteer",{"count":657,"type":23},200,"The main purpose of this research is to test the validity and reliability of the \"Exercise Health Beliefs Attitude Scale\" (EYSİTÖ), developed by Caz, Paktaş and Yazıcı (2023) for adult individuals, in geriatric individuals aged 65 and over.",[120,531],[661,662,663,537],"exercise behavior","pyhsical activity","motivatıon","2026-05-09",{"date":666,"type":39},"2026-05-13",{"date":668,"type":23},"2026-05-05",{"date":544,"type":23},{"name":45,"class":46},{"id":672,"slug":673,"hasResults":12,"nctId":674,"briefTitle":675,"officialTitle":676,"acronym":4,"eligibilityCriteria":677,"healthyVolunteers":17,"sex":18,"minAge":85,"maxAge":4,"enrollmentInfo":678,"targetDuration":202,"studyType":144,"phases":4,"briefSummary":679,"conditions":680,"keywords":681,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":664,"lastUpdatePostDateStruct":686,"startDateStruct":687,"completionDateStruct":689,"leadSponsor":690,"locationsCount":47},"100636220","comparison-of-hand-grip-strength-in-different-shoulder-positions-in-geriatric-individuals-position-dependent-strength-analysis-100636220","NCT07562854","Comparison of Hand Grip Strength in Different Shoulder Positions in Geriatric Individuals: Position-Dependent Strength Analysis","Comparison of Hand Grip Strength in Different Shoulder Positions in Geriatric Individuals: Position-Dependent Strength Analysis - A Cross-Sectional Analytical Study With Repeated Measurements","Inclusion Criteria:\n\n* Being 65 years of age or older\n* Being an independent volunteer living in the community\n* Being able to actively use the upper extremities\n* Having the cognitive level to understand and follow the measurement instructions\n* Providing written informed consent to participate in the study.\n\nExclusion Criteria:\n\n* Presence of severe shoulder pain or rotator cuff pathology\n* Loss of upper extremity function due to rheumatological disease\n* Presence of significant visual or vestibular impairment that may affect measurements\n* Presence of another systemic or musculoskeletal disease that may prevent the safe and accurate completion of tests\n* History of upper extremity surgery or fracture within the last 6 months\n* Failure to provide informed consent",{"count":113,"type":23},"The aim of this study is to examine the relationship between hand grip strength, measured in different shoulder positions, and upper extremity muscle strength, and to reveal the clinical significance of position-dependent strength variation.",[120,531],[682,683,684,685],"muscle strenght","hand grip strength","geriatrics","upper extremity muscle strength",{"date":666,"type":39},{"date":688,"type":23},"2026-05-02",{"date":544,"type":23},{"name":45,"class":46},""]