[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Istituto di Sistemi e Tecnologie Industriali Intelligenti per il Manifatturiero Avanzato\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":81},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,50],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":30,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":44,"leadSponsor":46,"locationsCount":49},"100639648","virtualparkpediatric-100639648",false,"NCT07580365","VirtualPark_Pediatric","Evaluation of the Impact of a Rehabilitation Intervention Based on Cycling With Virtual Park on Slowing the Functional Motor Decline of Neuromuscular Patients in Developmental Age","Inclusion Criteria:\n\n* availability of a definitive clinical or molecular genetic diagnosis of a neuromuscular disease;\n* age between 6 years and 17 years and 11 months (inclusive);\n* height compatible with the use of the Thera-Trainer (minimum 120 cm);\n* performance Upper Limb Module 2.0 assessment: Entry level \\>= 2\n\nExclusion Criteria:\n\n* other concomitant genetic diseases;\n* presence of visual impairments that prevent access to the experimental virtual reality protocol;\n* concomitant compromised cardio-respiratory function that contraindicates cycle ergometer training;\n* severe osteoporosis.","ALL","6 Years","18 Years",{"count":20,"type":21},22,"ESTIMATED","INTERVENTIONAL",[24],"NA","The goal of this clinical trial is to assess the effects of a dual-task, multimodal training program on slowing functional motor decline in children and adolescents with neuromuscular disorders. The main questions it aims to answer are:\n\nDoes Virtual Park slow functional motor decline in children and adolescents with neuromuscular diseases compared with standard therapy?\n\nDoes Virtual Park contribute to increased engagement and improved neuropsychological function?\n\nIf there is a comparison group, Researchers will compare dual-task cycling supported by the Virtual Park application to standard therapy to see whether it improves motor and neuropsychological functions and engagement.\n\nParticipants will undergo two phases:\n\n* Phase 1: 3 months of standard therapy;\n* Phase 2: 3 months of experimental conditions in which patients undergo a rehabilitative intervention with Virtual Park, 3 times a week.",[27,28,29],"Dystrophinopathy","Muscular Dystrophies","Congenital Myopathies",[31,32,33,34,35,36],"Sports for Persons with Disabilities","Rehabilitation","Neuromuscular Diseases","Dual-Task Exercises","Virtual Reality","Children with Disabilities","NOT_YET_RECRUITING","2026-05-05",{"date":40,"type":41},"2026-05-12","ACTUAL",{"date":43,"type":21},"2026-06",{"date":45,"type":21},"2028-06",{"name":47,"class":48},"Istituto di Sistemi e Tecnologie Industriali Intelligenti per il Manifatturiero Avanzato","OTHER",4,{"id":51,"slug":52,"hasResults":11,"nctId":53,"briefTitle":54,"officialTitle":55,"acronym":4,"eligibilityCriteria":56,"healthyVolunteers":11,"sex":16,"minAge":57,"maxAge":18,"enrollmentInfo":58,"targetDuration":4,"studyType":22,"phases":60,"briefSummary":61,"conditions":62,"keywords":65,"overallStatus":71,"whyStopped":4,"lastUpdateSubmitDate":72,"lastUpdatePostDateStruct":73,"startDateStruct":75,"completionDateStruct":77,"leadSponsor":79,"locationsCount":80},"100600049","pediatric-upper-limb-rehabilitation-with-phicube-a-modular-bilateral-end-effector-device-100600049","NCT07092436","Pediatric Upper-Limb Rehabilitation With PhiCube, a Modular Bilateral End-Effector Device","Pediatric Upper-Limb Rehabilitation With PhiCube, a Modular Bilateral End-Effector Device.","Inclusion Criteria:\n\n* For subjects with congenital and acquired neuromotor disorders:\n\n  * Diagnosis of congenital and acquired neuromotor disorders\n  * Age between 4 and 18 years at the time of recruitment\n  * Modified Ashworth Scale (MAS) less than 3\n  * MACS level I-IV\n  * Sufficient capacity to understand the proposed activities\n  * Availability to attend the facility\n* For subjects with developmental coordination disorder (DCD):\n\n  * Diagnosis of developmental coordination disorder (DCD)\n  * Age between 4 and 18 years at the time of recruitment\n  * Sufficient capacity to understand the proposed activities\n  * Availability to attend the facility\n\nExclusion Criteria:\n\n* For subjects with congenital and acquired neuromotor disorders:\n\n  * Severe sensory deficits\n  * Onset of pathologies that prevent participation\n  * Worsening of pre-existing comorbidities\n* For subjects with developmental coordination disorder (DCD):\n\n  * Severe sensory deficits\n  * Onset of pathologies that prevent participation\n  * Worsening of pre-existing comorbidities","4 Years",{"count":59,"type":21},54,[24],"The present investigation is configured as a multicenter clinical study in a within-group pilot phase.\n\nThis study aims to investigate primarily the feasibility of use and effectiveness of a treatment for upper limb function in children aged 4 to 18 years with congenital and acquired neuromotor disorders through a new portable robotic system, called PhiCube, designed for bilateral neuromotor rehabilitation of the upper limbs in subjects with neuromotor disorders.\n\nIn order to specifically investigate also the potential impact of PhiCube on movement planning aspects, the study will also involve a small group of children aged 4 to 18 years with Developmental Coordination Disorder (DCD).\n\nBefore (PreT0 and T0) and after (T1 and T2) treatment, standardized assessment tests will be administered. Regarding the investigation objectives reported above, the primary outcome measure will be the Melbourne Assessment-2 (MA2), a standardized, valid and reliable instrument for evaluating the quality of upper limb movement in children with neurological deficits, capable of measuring four elements of movement quality: range of motion, accuracy, dexterity and fluency. As secondary outcome measures, Abilhand-Kids has been chosen, a brief questionnaire that measures 21 main daily bimanual activities completed by the parent or caregiver, and various subtests and questionnaires aimed at evaluating the neuropsychological processes involved and the effects related to auditory feedback perception.\n\nThe treatment will have a total duration of approximately 3 months and will be organized in 3 weekly sessions lasting 45 minutes each, to reach a total of 30.\n\nDescriptive statistics of the clinical and technological variables obtained in the evaluation and rehabilitation phases will be calculated. Subsequently, treatment efficacy analyses through the robotic device are planned, comparing pre-post clinical variables. All collected data will finally be analyzed in order to compare the rehabilitative efficacy of the device with respect to the different groups of participants identified based on diagnostic profile.",[63,64],"Congenital and Acquired Neuromotor Disorders","Developmental Coordination Disorder (DCD)",[66,67,68,69,70],"Pediatric Rehabilitation","Upper Limb Rehabilitation","Robotic Rehabilitation","Bilateral Training","Neuromotor Disorders","RECRUITING","2026-04-01",{"date":74,"type":41},"2026-04-02",{"date":76,"type":41},"2025-11-17",{"date":78,"type":21},"2026-11",{"name":47,"class":48},6,""]