[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Ivoclar Vivadent AG\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":90},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,42,68],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":41},"100638802","effectiveness-of-two-different-desensitizing-dental-varnishes-100638802",false,"NCT07622043","Effectiveness of Two Different Desensitizing Dental Varnishes","Effectiveness of Two Different Desensitizing Dental Varnishes: A Prospective, Randomized Split Mouth Clinical Investigation","Inclusion Criteria:\n\n* Informed Consent signed by the subject\n* Age: 18-65 years\n* Hypersensitivity assessment scale ≥ Grade 2 in\n* two non-neighboring teeth in different quadrants\n* The affected teeth are\u002Fhave: vital, caries-free, received no restorations within the last month\n* No change in medication anticipated over the next 3 months (e.g. due to upcoming surgery etc.)\n\nExclusion Criteria:\n\n* Contraindications and limitations of the MD as described in the instructions for use.\n* Known hypersensitivity or allergy to the device material (especially acrylates, mint flavouring)\n* Pregnant or other vulnerable subjects\n* Participants with severe systemic disease\n* Enrolment of employees of the dental clinic of Ivoclar Vivadent AG\n* Recent change in medication concerning Analgesics, NSAIDs, psychotropic drugs, other medications that may alter pain perception\n* Intake of analgesics prior to appointment\n* Professional desensitizing therapy in the last 3 months\n* Bleaching procedures in the last 4 weeks\n* Confounding dental conditions at test sites: defective or extensive restorations, abutment teeth for prostheses, recent restorations, pulpitis\u002Fperiapical pathology.\n* Current or recent use of desensitizing toothpastes or mouthrinses (i.e. products specifically marketed for the treatment of dentin hypersensitivity) within 4 weeks prior to enrolment","ALL","18 Years","65 Years",{"count":20,"type":21},66,"ESTIMATED","INTERVENTIONAL",[24],"NA","Dental varnishes are commonly used to relieve dentin hypersensitivity by forming a protective film that occludes dentinal tubules and reduces fluid flow. This clinical investigation aims to compare the desensitizing effect of a fluoride containing varnish with a fluoride free placebo varnish. Primary and secondary objectives include evaluating short and long term reductions in dentinal hypersensitivity, assessing patient reported outcomes and daily experiences, and monitoring the varnish's tolerability and safety.",[27,28],"Dentin Hypersensitivity","Dentin Desensitizing Agents","NOT_YET_RECRUITING","2026-05-27",{"date":32,"type":33},"2026-06-02","ACTUAL",{"date":35,"type":21},"2026-08",{"date":37,"type":21},"2027-08",{"name":39,"class":40},"Ivoclar Vivadent AG","INDUSTRY",1,{"id":43,"slug":44,"hasResults":11,"nctId":45,"briefTitle":46,"officialTitle":47,"acronym":4,"eligibilityCriteria":48,"healthyVolunteers":11,"sex":16,"minAge":49,"maxAge":50,"enrollmentInfo":51,"targetDuration":4,"studyType":22,"phases":53,"briefSummary":54,"conditions":55,"keywords":4,"overallStatus":58,"whyStopped":4,"lastUpdateSubmitDate":59,"lastUpdatePostDateStruct":60,"startDateStruct":62,"completionDateStruct":64,"leadSponsor":66,"locationsCount":67},"100609290","a-clinical-trial-to-compare-the-safety-and-performance-of-two-different-curing-modes-in-the-direct-filling-therapy-in-deciduous-teeth-100609290","NCT07212660","A Clinical Trial to Compare the Safety and Performance of Two Different Curing Modes in the Direct Filling Therapy in Deciduous Teeth","A Multi-center, Randomized-controlled, 12-month, Split-mouth, Non-inferiority Clinical Trial to Compare the Safety and Performance of Two Different Curing Modes in the Direct Filling Therapy With a Flowable Bulk Fill Composite in Class I and II Deciduous Teeth","Inclusion Criteria:\n\n* Consent of a legal representative (usually parents)\n* 2 deciduous molars in the need of direct filling therapy class I and\u002For II in different quadrants (primary or secondary caries, filling loss)\n* Classification of caries: caries of all sizes in deciduous molars are included unless they can be treated with fissure sealing (ICDAS 3, 4, 5)\n* Sufficient language skills of legal representative and children\n* Teeth in the need of indirect pulp capping if necessary (Operator decision)\n\nExclusion Criteria:\n\n* Cognitive impairment not age-appropriate\n* Sensitive tooth (pain at night, irritation-persistent pain, buccal swelling, percussion sensitivity)\n* Teeth with severely resorbed roots (anormal tooth mobility)\n* Direct pulp capping\n* Pulpotomy of an adjacent tooth in the same appointment\n* Noncompliant child\n* Allergies to material or anaesthetics used in the study\n* Sufficient isolation not possible","4 Years","9 Years",{"count":52,"type":21},70,[24],"The overall aim of this clinical investigation is to assess the clinical performance and safety of composite restorations cured with fast curing mode (5 seconds with 2000 mW\u002Fcm²) in primary molars.",[56,57],"Dental Caries","Insufficient Dental Filling","RECRUITING","2026-03-24",{"date":61,"type":33},"2026-03-25",{"date":63,"type":33},"2025-12-18",{"date":65,"type":21},"2027-10",{"name":39,"class":40},2,{"id":69,"slug":70,"hasResults":11,"nctId":71,"briefTitle":72,"officialTitle":72,"acronym":4,"eligibilityCriteria":73,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":74,"targetDuration":4,"studyType":22,"phases":75,"briefSummary":76,"conditions":77,"keywords":80,"overallStatus":58,"whyStopped":4,"lastUpdateSubmitDate":82,"lastUpdatePostDateStruct":83,"startDateStruct":85,"completionDateStruct":87,"leadSponsor":89,"locationsCount":41},"100529391","clinical-evaluation-of-full-contour-zirconia-chairside-cadcam-crowns-100529391","NCT06173167","Clinical Evaluation of Full Contour Zirconia Chairside CAD\u002FCAM Crowns","Inclusion Criteria:\n\n* at least 18 years of age\n* at least one carious lesion, defective restoration, or fractured portion of the tooth to be restored on a maxillary or mandibular premolar or molar tooth - Each lesion, fracture, or defective restoration should exhibit sufficient size or loss of tooth structure requiring a full crown restoration.\n* tooth should have at least one opposing tooth in occlusion and one adjacent tooth with an intact proximal contact\n* No more than ten teeth that are endodontically treated may be included in the study, equally divided between the two groups of crowns. All remaining teeth in the study will test vital and be asymptomatic at the beginning of treatment.\n* No more than two restorations will be placed per patient\n\nExclusion Criteria:\n\n* Sensitive teeth\n* Teeth with a history of direct or indirect pulp capping procedures\n* Patients with significant untreated dental disease to include periodontitis and\u002For rampant caries\n* Women who self-report that they are possibly pregnant, pregnant, or lactating, as elective dental treatment is not indicated at these times\n* Patients with a self-reported history of allergies to the materials to be used in the study including composite resin cements or zirconia restorative materials\n* Patients unable to return for the recall appointments",{"count":52,"type":21},[24],"This investigation will be a randomized, prospective, longitudinal clinical trial to study the clinical performance of a new monolithic, zirconia material with shade, translucency and material graduation for chairside CAD\u002FCAM crowns. The restorations will be luted either with a self-adhesive luting material or a conventional cement. The crowns will be evaluated for a period of two years.",[78,79],"Dental Disorders Hard Tissues of Teeth","Dental Diseases",[81],"Dental Caries, Caries","2024-03-27",{"date":84,"type":33},"2024-03-28",{"date":86,"type":33},"2024-01-08",{"date":88,"type":21},"2026-12-31",{"name":39,"class":40},""]