[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Izgi Miray Demirbag\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":47},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":29,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":5},"100605535","the-effect-of-the-hep-approach-in-infants-with-down-syndrome-100605535",false,"NCT07163780","The Effect of the HEP Approach in Infants With Down Syndrome","The Effectiveness of the HEP (Homeostasis-Enrichment-Plasticity) Approach in Infants With Down Syndrome","HEP-DS","Inclusion Criteria:\n\n* Must be between 4 and 12 months old\n* Must have been diagnosed with Down Syndrome\n* Must not be at any neurological risk\n* Parent must agree to participate regularly in the study process\n\nExclusion Criteria:\n\n* History of intraventricular hemorrhage (Grade III or IV)\n* Major vision or hearing impairment\n* History of febrile convulsion\n* Medical conditions (e.g., oxygen dependence) that prevent active participation in the study\n* Participation in other experimental rehabilitation studies","ALL","4 Months","12 Months",{"count":21,"type":22},26,"ESTIMATED","INTERVENTIONAL",[25],"NA","This study evaluates the effect of the HEP (Homeostasis-Enrichment-Plasticity) approach on motor and sensory development in infants with Down syndrome. Thirty-two infants will receive either HEP or traditional therapy over 12 sessions, and outcomes will be measured using standardized developmental tests.",[28],"Down Syndrome (DS)",[30,31,32,33,34],"Down Syndrome","Infants","Early Intervention","Neuroplasticity","Environmental Enrichment","RECRUITING","2025-11-13",{"date":38,"type":39},"2025-11-14","ACTUAL",{"date":41,"type":39},"2025-09-03",{"date":43,"type":22},"2025-12-03",{"name":45,"class":46},"Izgi Miray Demirbag","OTHER",""]