[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Izmir Dr Suat Seren Chest Diseases and Surgery Education and Research Hospital\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":98},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,45,71],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":22,"studyType":23,"phases":4,"briefSummary":24,"conditions":25,"keywords":28,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":39,"leadSponsor":41,"locationsCount":44},"100618947","sofa-2-score-in-turkish-icus-100618947",false,"NCT07338240","SOFA-2 Score in Turkish ICUs","Real-Time Validation and Feasibility of the SOFA-2 Score in Adult Intensive Care Units in Türkiye (TR-SOFA2): A Multicenter Prospective Observational Study","TR-SOFA2","Inclusion Criteria:\n\n* Adults aged 18 years or older\n* Admission to a participating intensive care unit in Türkiye\n* Intensive care unit stay longer than 24 hours\n\nExclusion Criteria:\n\n* Patients younger than 18 years\n* Pregnant patients\n* Organ donors\n* Patients with unknown intensive care unit discharge outcomes","ALL","18 Years",{"count":20,"type":21},5200,"ESTIMATED","60 Days","OBSERVATIONAL","This study aims to evaluate how well a new scoring system called the Sequential Organ Failure Assessment-2 (SOFA-2) works in adult intensive care units in Türkiye.\n\nSOFA-2 is designed to measure the severity of organ dysfunction in critically ill patients using routinely collected clinical and laboratory data. It is an updated version of the original SOFA score and reflects modern intensive care practices.\n\nIn this multicenter observational study, adult patients admitted to participating intensive care units will be followed during their ICU stay. SOFA and SOFA-2 scores will be calculated during the first 24 hours of admission, and in patients with longer stays, additional scores will be recorded. No additional tests or treatments will be performed as part of the study.\n\nThe main goal of the study is to examine the relationship between SOFA-2 scores and intensive care unit mortality. The results are expected to help clinicians better assess disease severity and outcomes in critically ill patients.",[26,27],"Intensive Care Unit Patients","Critically Ill Intensive Care Unit Patients",[29,30,31,32],"SOFA-2 Score","Critical Illness","ICU Mortality","Prognostic Scoring System","RECRUITING","2026-01-19",{"date":36,"type":37},"2026-01-21","ACTUAL",{"date":34,"type":37},{"date":40,"type":21},"2026-07",{"name":42,"class":43},"Izmir Dr Suat Seren Chest Diseases and Surgery Education and Research Hospital","OTHER",1,{"id":46,"slug":47,"hasResults":11,"nctId":48,"briefTitle":49,"officialTitle":50,"acronym":4,"eligibilityCriteria":51,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":52,"targetDuration":4,"studyType":54,"phases":55,"briefSummary":57,"conditions":58,"keywords":60,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":63,"lastUpdatePostDateStruct":64,"startDateStruct":66,"completionDateStruct":68,"leadSponsor":70,"locationsCount":44},"100443335","telerehabilitation-in-copd-100443335","NCT05053061","Telerehabilitation in COPD","Does Pulmonary Rehabilitation With Telerehabilitation Increase Physical Capacity in Patients With Chronic Obstructive Pulmonary Disease","Inclusion Criteria:\n\n* Age ≥ 18 years\n* Being diagnosed with COPD\n* Not have previously participated in pulmonary rehabilitation\n* To able to use smartphone\n\nExclusion Criteria:\n\n* Under age 18\n* Pregnancy\n* Have previously participated in pulmonary rehabilitation\n* Having any malignacy\n* Having any disorder that limit exercise",{"count":53,"type":21},21,"INTERVENTIONAL",[56],"NA","The prevalence of chronic obstructive pulmonary disease (COPD) in Turkey is 10%. Patients with COPD have a decreased physical capacity. Decreased physical activity in COPD patients causes an increase in all-cause mortality. Pulmonary rehabilitation contributes to increasing physical capacity and quality of life in COPD patients. However, a limited number of patients have access to pulmonary rehabilitation. Some of the patients drop out of pulmonary rehabilitation due to reasons such as transport difficulties, low social support, and low professional support. In addition, disruption of daily routine is one of the important reasons for this situation. Telerehabilitation can enable more patients to access pulmonary rehabilitation. Education and exercise programs can be followed with telerehabilitation in patients with COPD. An increase in exercise capacity and a decrease in dyspnea have been achieved with telerehabilitation in COPD patients.\n\nDifferent technologies such as telephone, video conferencing or web sites can be used for telerehabilitation. Also, mobile phone was used to telerehabilitation. To make pulmonary telerehabilitation completely patient-based, we have developed an application suitable for smartphones. The application contains videos which showing how to perform pulmonary rehabilitation exercise videos, and it allows the participants to follow up compliance with pulmonary rehabilitation daily. The application will be downloaded to the smartphones of the participants, and it will be shown how to use the application. Participants will not be shown pulmonary rehabilitation exercises.\n\nThis study aims to evaluate the effectiveness of telerehabilitation with the application program on physical capacity, quality of life, and dyspnea perception in COPD patients.",[59],"COPD",[59,61,62],"Pulmonary Rehabilitation","Telerehabilitation","2024-10-12",{"date":65,"type":37},"2024-10-15",{"date":67,"type":37},"2021-08-25",{"date":69,"type":21},"2025-01-31",{"name":42,"class":43},{"id":72,"slug":73,"hasResults":11,"nctId":74,"briefTitle":75,"officialTitle":76,"acronym":77,"eligibilityCriteria":78,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":79,"targetDuration":4,"studyType":54,"phases":81,"briefSummary":82,"conditions":83,"keywords":85,"overallStatus":91,"whyStopped":4,"lastUpdateSubmitDate":63,"lastUpdatePostDateStruct":92,"startDateStruct":93,"completionDateStruct":95,"leadSponsor":97,"locationsCount":44},"100369344","closed-loop-ventilation-with-high-tidal-volumes-and-safe-transpulmonary-pressure-in-copd-copd-safe-100369344","NCT04089111","Closed Loop Ventilation With High Tidal Volumes and Safe Transpulmonary Pressure in COPD (COPD-SAFE)","Does Automatically Generated Tidal Volumes With Closed-loop Ventilation Leads to Safe Transpulmonary Pressures in Intubated Chronic Obstructive Pulmonary Disease Patients?","COPD-SAFE","Inclusion Criteria:\n\n* Acute exacerbation of Chronic Obstructive Lung Disease\n* Being intubated for less than 24 hours\n* Not being planned to be extubated in 24 hours\n* Expiratory time constant (RCexp) more than \\> 2.0 s\n\nExclusion Criteria:\n\n* Restrictive lung pathologies\n* Impaired hemodynamic status\n* Esophageal pathologies\n* Bronchopleural fistula",{"count":80,"type":21},20,[56],"This study evaluates the safety and efficacy of high tidal volumes generated by \"Adapted Support Ventilation (ASV) mode' in mechanically ventilated severe COPD patients. Every patient will be ventilated consecutively with ASV and Volume Control (VC) modes at 2 different levels of minute volume in 2 sets. ASV mode is expected to be safe measured by adequate inspiratory transpulmonary pressures and expected to be as effective as VC mode with lower intrinsic positive end expiratory pressure (iPEEP) levels.",[84],"Chronic Obstructive Pulmonary Disease",[86,87,88,89,90],"Mechanical ventilation","Adaptive Support Ventilation","Transpulmonary pressure","Intrinsic PEEP","Safety","NOT_YET_RECRUITING",{"date":65,"type":37},{"date":94,"type":21},"2024-12",{"date":96,"type":21},"2025-02",{"name":42,"class":43},""]