[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Izmir Katip Celebi University\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":663},{"pageToken":4,"total":5,"offset":6,"count":7,"results":8},null,26,0,25,[9,47,74,97,122,153,181,216,240,263,290,320,351,380,402,425,453,474,499,526,553,578,597,618,642],{"id":10,"slug":11,"hasResults":12,"nctId":13,"briefTitle":14,"officialTitle":15,"acronym":4,"eligibilityCriteria":16,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":29,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100643900","effect-of-tens-on-spasticity-100643900",false,"NCT07669649","Effect of TENS on Spasticity","The Effect of Transcutaneous Electrical Nerve Stimulation on Spasticity: A Single-Subject Experimental Study","Inclusion Criteria:\n\n* Age between 18 and 70 years\n* Post-stroke wrist flexor spasticity scored as Grade 2 or 3 on the Australian Spasticity Assessment Scale (ASAS), specifically selecting patients whose passive stretch resistance (post-catch response) can be easily overcome to ensure accurate and unconfounded electrophysiological evaluation.\n* At least 6 months post-stroke (chronic phase).\n* Provision of voluntary, written informed consent prior to study enrollment.\n\nExclusion Criteria:\n\n* Age \\\u003C18 or \\>70 year\n* Contraindications to transcutaneous electrical nerve stimulation (e.g., implanted electronic devices, history of epilepsy, or localized skin lesions preventing electrode placement)\n* Concomitant wrist contracture or pain sufficient to impede clinical evaluation\n* Structural abnormalities of the elbow joint obstructing median nerve stimulation\n* Median nerve neuropathy or injury in the affected upper extremity.\n* Non-stable dosage of antispastic medications within the 2 weeks prior to baseline\n* Initiation of medications affecting nerve conduction (e.g., antidepressants, anticonvulsants, anesthetics) within the past month; patients on a stable dose for \\>1 month remain eligible\n* Botulinum toxin injection in the target spastic muscles within the preceding 3 months\n* History of neurolytic procedures targeting spasticity in the affected limb.\n* History of orthopedic or neurological surgery targeting spasticity in the affected limb\n* Cognitive impairment severe enough to compromise adherence to study protocols\n* Inability to maintain the required testing positions for the upper extremity joints (shoulder, elbow, forearm, and wrist)\n* Pregnancy or breastfeeding\n* Presence of active malignancy at or near the treatment area.","ALL","18 Years","70 Years",{"count":21,"type":22},4,"ESTIMATED","INTERVENTIONAL",[25],"NA","The purpose of this clinical trial is to evaluate whether Transcutaneous Electrical Nerve Stimulation (TENS) is effective in reducing spasticity in adults with post-stroke spasticity. The primary research question is whether TENS can reduce the severity of spasticity. The effectiveness of TENS will be assessed by comparing spasticity-related outcomes measured before, during, and after the intervention. Participants will first undergo a one-hour baseline monitoring period, during which assessments will be conducted at 10-minute intervals. This will be followed by a 30-minute TENS intervention and a two-hour follow-up period, with assessments performed every 10 minutes. One participant will repeat this protocol once daily for three consecutive days, whereas the remaining three participants will undergo the procedure on a single occasion.",[28],"Post Stroke Spasticity",[30,31,32,33],"Post stroke spasticity","Transcutaneous electrical nerve stimulation","Muscle reaction angle","H reflex","NOT_YET_RECRUITING","2026-06-20",{"date":37,"type":38},"2026-06-25","ACTUAL",{"date":40,"type":22},"2026-06",{"date":42,"type":22},"2027-06",{"name":44,"class":45},"Izmir Katip Celebi University","OTHER",1,{"id":48,"slug":49,"hasResults":12,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":4,"eligibilityCriteria":53,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":54,"enrollmentInfo":55,"targetDuration":4,"studyType":23,"phases":57,"briefSummary":51,"conditions":58,"keywords":60,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":46},"100643309","effects-of-cervical-and-oculomotor-exercises-on-functional-status-balance-and-proprioception-in-chronic-ankle-instability-100643309","NCT07581535","Effects of Cervical and Oculomotor Exercises on Functional Status, Balance, and Proprioception in Chronic Ankle Instability","Effects of Cervical and Oculomotor Exercises Added to Conventional Treatment on Ankle Functional Status, Balance, and Proprioception in Individuals With Chronic Ankle Instability: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Diagnosed with unilateral chronic ankle instability (CAI) in accordance with the International Ankle Consortium recommendations\n* A history of at least one significant lateral ankle sprain that occurred at least 12 months prior to participation, resulting in inflammatory symptoms such as pain and swelling and causing at least one day of interruption in physical activity\n* A history of \"giving way\" and\u002For recurrent ankle sprains and\u002For a feeling of instability in the affected ankle within the past 6 months\n* A Cumberland Ankle Instability Tool (CAIT) score of ≤ 25\n\nExclusion Criteria:\n\n* History of surgery or fracture in the lower extremities or spine\n* Acute musculoskeletal injury affecting other joints of the lower extremity within the past 3 months (e.g., sprains, fractures) that impaired joint integrity and function and caused at least one day of interruption in physical activity\n* History of injection in the affected ankle\n* History of ankle sprain in the affected extremity within the past 4 weeks\n* Presence of systemic musculoskeletal disorders, neurological disorders, vestibular disorders, or any other condition that may affect balance or sensory function\n* Previous participation in any rehabilitation program for the ankle or cervical region\n* History of head or neck trauma or diagnosed pathology within the past 12 months\n* History of neck pain greater than 3\u002F10 in severity within the past 12 months","45 Years",{"count":56,"type":22},38,[25],[59],"Chronic Ankle Instability, CAI",[61,62,63,64],"Postural Balance","Proprioception","Rehabilitation","Ankle Instability","RECRUITING","2026-06-04",{"date":68,"type":38},"2026-06-08",{"date":70,"type":22},"2026-06-07",{"date":72,"type":22},"2027-06-07",{"name":44,"class":45},{"id":75,"slug":76,"hasResults":12,"nctId":77,"briefTitle":78,"officialTitle":79,"acronym":4,"eligibilityCriteria":80,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":81,"targetDuration":4,"studyType":23,"phases":82,"briefSummary":83,"conditions":84,"keywords":86,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":89,"lastUpdatePostDateStruct":90,"startDateStruct":92,"completionDateStruct":94,"leadSponsor":96,"locationsCount":46},"100637487","effect-of-nmes-on-spasticity-100637487","NCT07617311","Effect of NMES on Spasticity","The Effect of Neuromuscular Electrical Stimulation on Spasticity: A Single-Subject Experimental Study","Inclusion Criteria:\n\n* Age between 18 and 70 years\n* Post-stroke wrist flexor spasticity scored as Grade 2 or 3 on the Australian Spasticity Assessment Scale (ASAS), specifically selecting patients whose passive stretch resistance (post-catch response) can be easily overcome to ensure accurate and unconfounded electrophysiological evaluation.\n* Provision of voluntary, written informed consent prior to study enrollment.\n\nExclusion Criteria:\n\n* Age \\\u003C18 or \\>70 year\n* Contraindications to neuromuscular electrical stimulation (e.g., active electronic implants, history of epilepsy, or localized skin lesions preventing electrode placement)\n* Concomitant wrist contracture or pain sufficient to impede clinical evaluation\n* Structural abnormalities of the elbow joint obstructing median nerve stimulation\n* Median nerve neuropathy or injury in the ipsilateral upper extremity.\n* Non-stable dosage of antispastic medications within the 2 weeks prior to baseline\n* Initiation of medications affecting nerve conduction (e.g., antidepressants, anticonvulsants, anesthetics) within the past month; patients on a stable dose for \\>1 month remain eligible\n* Botulinum toxin infiltration in the target spastic muscles within the preceding 3 months\n* History of neurolytic procedures targeting spasticity in the affected limb.\n* History of orthopedic or neurological surgery targeting spasticity in the affected limb\n* Cognitive impairment severe enough to compromise adherence to study protocols\n* Inability to maintain the required testing positions for the upper extremity joints (shoulder, elbow, forearm, and wrist)\n* Pregnancy",{"count":21,"type":22},[25],"The goal of this clinical trial is to learn if neuromuscular electrical stimulation (NMES) works to treat spasticity in adult patients with spasticity related to stroke. The main question it aims to answer is:\n\n• Does NMES reduces the severity of spasticity? Researchers will compare NMES treatment to baseline and non-stimulation periods to see if NMES works to treat spasticity.\n\nParticipants will:\n\n• first undergo an initial assessment at 10-minute intervals for one hour, followed by 20 minutes of NMES exposure, and subsequent post-treatment assessments at 10-minute intervals for two hours. This daily procedure will be repeated over four days for one patient, and performed only once for the remaining three patients.",[85],"Post-Stroke Spasticity",[87,88,32,33],"Post-stroke spasticity","Neuromuscular electrical stimulation","2026-05-31",{"date":91,"type":38},"2026-06-03",{"date":93,"type":22},"2026-06-15",{"date":95,"type":22},"2028-03-16",{"name":44,"class":45},{"id":98,"slug":99,"hasResults":12,"nctId":100,"briefTitle":101,"officialTitle":102,"acronym":103,"eligibilityCriteria":104,"healthyVolunteers":105,"sex":17,"minAge":106,"maxAge":107,"enrollmentInfo":108,"targetDuration":4,"studyType":23,"phases":110,"briefSummary":111,"conditions":112,"keywords":4,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":114,"lastUpdatePostDateStruct":115,"startDateStruct":117,"completionDateStruct":119,"leadSponsor":121,"locationsCount":46},"100636642","comparison-of-supervised-rehabilitation-and-home-exercise-programs-in-subacromial-impingement-syndrome-100636642","NCT07568340","Comparison of Supervised Rehabilitation and Home Exercise Programs in Subacromial Impingement Syndrome","Comparison of the Effectiveness of a Physiotherapist-Supervised Rehabilitation Program and Home Exercise Education in Subacromial Impingement Syndrome","SAIS-REHAB","Inclusion Criteria:\n\n* Voluntary participation in the study\n* Literate in Turkish\n* Aged between 30 and 65 years\n* No visual or hearing impairment\n* Diagnosed with unilateral subacromial impingement syndrome by a specialist physician\n* Positive painful arc test, Infraspinatus test, and Hawkins-Kennedy test\n* Pain during overhead activities\n\nExclusion Criteria:\n\n* Presence of a mental or psychological disorder that may affect study findings\n* Inadequate cooperation\n* History of upper extremity fracture within the last 6 months\n* Presence of cervical neurological symptoms\n* Glenohumeral instability\n* Acromioclavicular joint pathology\n* Full-thickness rotator cuff tear or total rupture\n* Signs of glenohumeral osteoarthritis\n* History of frozen shoulder",true,"30 Years","65 Years",{"count":109,"type":22},63,[25],"This randomized controlled trial aims to compare the effectiveness of physiotherapist-supervised rehabilitation and home exercise programs in individuals with subacromial impingement syndrome (SAIS). SAIS is a common musculoskeletal disorder characterized by shoulder pain, reduced range of motion, and functional limitations, negatively affecting quality of life.\n\nParticipants diagnosed with SAIS will be randomly assigned to one of three groups: a supervised rehabilitation group, a home exercise group, or a control group. Randomization will be performed using an online randomization tool. Individuals in the supervised rehabilitation group will receive a structured physiotherapy program administered by a physiotherapist, while those in the home exercise group will perform a standardized exercise program at home following initial instruction. Participants in the control group will not receive any intervention during the study period and will be assessed only.\n\nOutcome measures including pain intensity, upper extremity function, range of motion, grip strength, sleep quality, and quality of life will be evaluated at baseline and after the intervention period. The results of this study are expected to provide evidence regarding the comparative effectiveness of supervised and home-based exercise approaches in the management of SAIS.",[113],"Subacromial Impingement Syndrome","2026-05-05",{"date":116,"type":38},"2026-05-08",{"date":118,"type":38},"2025-12-02",{"date":120,"type":22},"2026-09-02",{"name":44,"class":45},{"id":123,"slug":124,"hasResults":12,"nctId":125,"briefTitle":126,"officialTitle":127,"acronym":4,"eligibilityCriteria":128,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":129,"enrollmentInfo":130,"targetDuration":4,"studyType":23,"phases":132,"briefSummary":134,"conditions":135,"keywords":139,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":145,"lastUpdatePostDateStruct":146,"startDateStruct":148,"completionDateStruct":150,"leadSponsor":152,"locationsCount":46},"100633781","phase-4-effects-of-flurbiprofen-spray-and-ice-cream-for-pain-and-voice-outcomes-after-thyroidectomy-100633781","NCT07531147","Effects of Flurbiprofen Spray and Ice Cream for Pain and Voice Outcomes After Thyroidectomy","Comparison of the Effects of Postoperative Oral Flurbiprofen (0.25%) Spray and Ice Cream on Analgesia and Voice Quality in Patients Undergoing Thyroidectomy","Inclusion Criteria:\n\n* No history of neck surgery\n* Age between 18-85 years\n* Undergoing thyroidectomy\n* Agreeing to participate in the study\n* Operation duration between 60-120 minutes\n\nExclusion Criteria:\n\n* History of neck surgery\n* History of radiotherapy to the head and neck region\n* Pre-operative or post-operative vocal cord paralysis\n* Pre-operative phonetic disorder\n* Pre-operative laryngeal pathology\n* Being under 18 years of age\n* Refusal to participate in the study\n* Smoking\n* Flurbiprofen allergy\n* Lactose intolerance","85 Years",{"count":131,"type":22},100,[133],"PHASE4","Researchers will compare oral flurbiprofen (%0.25) spray and ice cream to a placebo (a look-alike substance that contains no drug) to see if oral flurbiprofen (%0.25) spray and ice cream works to effect post-thyroidectomy throat pain and voice quality.\n\nParticipants will:\n\n* Receive 1 puff of oral flurbiprofen (0.25%) spray or 105 ml of ice cream or 1 puff of oral spray prepared with drinking water (placebo) at 5 hours postoperatively according to randomization result\n* Undergo voice analysis using Praat voice analysis (University of Amsterdam) at 6 hours postoperatively\n* Undergo a visual analog scale for analgesia status at 6 hours postoperatively",[136,137,138],"Thyroidectomy","Sore Throat","Voice Quality",[140,141,142,143,144],"thyroidectomy","sore throat","voice quality","flurbiprofen","ice cream","2026-04-11",{"date":147,"type":38},"2026-04-15",{"date":149,"type":22},"2026-04",{"date":151,"type":22},"2026-09",{"name":44,"class":45},{"id":154,"slug":155,"hasResults":12,"nctId":156,"briefTitle":157,"officialTitle":158,"acronym":4,"eligibilityCriteria":159,"healthyVolunteers":105,"sex":17,"minAge":160,"maxAge":161,"enrollmentInfo":162,"targetDuration":4,"studyType":23,"phases":164,"briefSummary":165,"conditions":166,"keywords":169,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":173,"lastUpdatePostDateStruct":174,"startDateStruct":176,"completionDateStruct":178,"leadSponsor":180,"locationsCount":46},"100633275","comparison-of-digital-intraosseous-and-manual-intraligamentary-anesthesia-in-children-100633275","NCT07524569","Comparison of Digital Intraosseous and Manual Intraligamentary Anesthesia in Children","Comparison of Digital Intraosseous and Manual Intraligamentary Anesthesia in Children: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Subjects with American Society of Anesthesiologists score I (ASA I)\n* Subjects with Frankl's behavior rate III (positive) and IV (definitely positive),\n* Subjects with indication of similar restoration treatment on bilateral first -permanent mandibular molars\n* Subjects whose plaque index score of 0 (no plaque) and 1\n* Subjects whose gingival index score of 0\n\nExclusion Criteria:\n\n* Allergic to the local anesthetics or sulfites\n* Subjects with cholinesterase deficiency\n* Subjects who use drugs that may affect the assessment of pain, such as narcotic or non-narcotic analgesic, anti-inflammatory, anxiolytic, antipsychotic and antihistamine agents\n* Subjects who need to use sedatives or other medications during dental procedures","6 Years","12 Years",{"count":163,"type":22},78,[25],"The aim of this study is to compare the effects of digital intraosseous anesthesia and manual intraligamentary anesthesia techniques on pain scores during the restorative treatment of permanent mandibular molars in pediatric patients. In addition, the techniques will be compared in terms of injection pain, anesthetic success, postoperative complications, and patient preferences. This randomized, controlled, crossover, single-blind, split-mouth study will be conducted on 78 children aged 6-12 years. Participants with bilateral permanent mandibular molars presenting enamel-dentin carious lesions will be included in the study.",[167,168],"Anesthesia","Local",[170,171,172],"intraligamentary anesthesia","paediatric dentistry","Digital Intraosseous Anesthesia","2026-04-05",{"date":175,"type":38},"2026-04-13",{"date":177,"type":22},"2026-04-01",{"date":179,"type":22},"2027-10",{"name":44,"class":45},{"id":182,"slug":183,"hasResults":12,"nctId":184,"briefTitle":185,"officialTitle":186,"acronym":187,"eligibilityCriteria":188,"healthyVolunteers":12,"sex":189,"minAge":18,"maxAge":107,"enrollmentInfo":190,"targetDuration":4,"studyType":23,"phases":192,"briefSummary":193,"conditions":194,"keywords":201,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":208,"lastUpdatePostDateStruct":209,"startDateStruct":211,"completionDateStruct":213,"leadSponsor":215,"locationsCount":46},"100598777","dynamic-neuromuscular-stabilization-vs-pelvic-floor-muscle-training-in-women-with-stress-urinary-incontinence-100598777","NCT07075900","Dynamic Neuromuscular Stabilization vs Pelvic Floor Muscle Training in Women With Stress Urinary Incontinence","Comparison of Effects of Dynamic Neuromuscular Stabilization Training and Pelvic Floor Muscle Training in Women With Stress Urinary Incontinence: A Randomized Controlled Trial","DYNA-SUI","Inclusion Criteria:\n\n* Female participants aged between 18 and 65 years\n* Diagnosed with stress urinary incontinence or stress-dominant mixed urinary incontinence by a specialist physician\n* Having the ability to voluntarily contract the pelvic floor muscles\n* Literate in Turkish\n* Willing and voluntarily consenting to participate in the study\n\nExclusion Criteria:\n\n* Pregnancy\n* Presence of urgency-predominant urinary incontinence symptoms or fecal incontinence\n* Inability to understand or cooperate with assessment procedures\n* Presence of any neurological or rheumatological disease\n* Severe cardiac or pulmonary disease\n* Uncontrolled diabetes mellitus or hypertension\n* Chronic liver and\u002For kidney failure\n* Advanced pelvic organ prolapse (greater than grade 2)\n* History of abdominal or pelvic surgery (including cesarean section) within the past year\n* History of spinal surgery\n* Current urinary tract infection\n* History of pelvic radiation therapy\n* Presence of spinal deformity\n* History of acute low back pain within the past 4-6 weeks\n* Receiving pelvic floor muscle training within the past three months","FEMALE",{"count":191,"type":22},51,[25],"This randomized controlled trial aims to compare the pre- and post-treatment effects of Dynamic Neuromuscular Stabilization (DNS) training and Pelvic Floor Muscle Training (PFMT) on pelvic floor muscle function, pelvic floor morphometry, urinary symptoms, quality of life, sexual function, and physical activity levels in women with stress urinary incontinence (SUI).\n\nParticipants diagnosed with SUI by a specialist physician will be randomly assigned to one of three groups: DNS, PFMT, or a control group. Both DNS and PFMT interventions will be delivered as 12-week home exercise programs, performed five days a week and at least three times per day. To support adherence, participants will use an exercise diary. In addition, participants in the DNS and PFMT groups will attend the clinic twice a week for supervised sessions led by a physiotherapist.\n\nThe control group will receive a brochure containing lifestyle and bladder health recommendations but will not engage in any structured exercise program.",[195,196,197,198,199,200],"Stress Urinary Incontinence (SUI)","Dynamic Neuromuscular Stabilization","Pelvic Floor Muscle Training","Muscle Morphology","Urinary Symptoms","Quality of Life",[202,203,204,205,206,207],"stress urinary incontinence","dynamic neuromuscular stabilization","pelvic floor muscle training","physical activity","quality of life","muscle morphology","2026-03-24",{"date":210,"type":38},"2026-03-25",{"date":212,"type":38},"2025-07-16",{"date":214,"type":22},"2026-12-30",{"name":44,"class":45},{"id":217,"slug":218,"hasResults":12,"nctId":219,"briefTitle":220,"officialTitle":221,"acronym":4,"eligibilityCriteria":222,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":223,"targetDuration":4,"studyType":23,"phases":225,"briefSummary":226,"conditions":227,"keywords":229,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":233,"lastUpdatePostDateStruct":234,"startDateStruct":236,"completionDateStruct":238,"leadSponsor":239,"locationsCount":46},"100629611","the-effect-of-corrective-exercises-in-individuals-with-chronic-neck-pain-100629611","NCT07476924","The Effect of Corrective Exercises in Individuals With Chronic Neck Pain","The Effect of Corrective Exercises on Pain, Functionality, and Dual-Task Gait in Individuals With Chronic Neck Pain","Inclusion Criteria:\n\n* Individuals aged 18 years and over\n* Individuals who have had neck pain for at least 3 months\n* Individuals with a Neck Disability Index (NDI) score of 10 or higher\n* Individuals who are able to understand the statements on the scale\n* Individuals who voluntarily agree to participate in the study after being informed about the study\n\nExclusion Criteria\n\n* Individuals who have received physiotherapy for neck pain within the last 6 months\n* Individuals who have undergone neck surgery\n* Individuals with sensory loss\n* Individuals diagnosed with orthopedic, neurological, or vestibular disorders\n* Individuals with a history of trauma (whiplash)\n* Individuals diagnosed with or treated for cancer or osteoporosis",{"count":224,"type":22},70,[25],"Our study will investigate the effects of corrective exercises on pain, functionality, and gait in individuals with chronic neck pain.",[228],"Neck Pain",[230,231,232],"corrective exercise","gait","dual-task","2026-03-12",{"date":235,"type":38},"2026-03-17",{"date":237,"type":22},"2026-03-10",{"date":40,"type":22},{"name":44,"class":45},{"id":241,"slug":242,"hasResults":12,"nctId":243,"briefTitle":244,"officialTitle":245,"acronym":4,"eligibilityCriteria":246,"healthyVolunteers":105,"sex":17,"minAge":18,"maxAge":247,"enrollmentInfo":248,"targetDuration":4,"studyType":23,"phases":250,"briefSummary":251,"conditions":252,"keywords":254,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":237,"lastUpdatePostDateStruct":258,"startDateStruct":259,"completionDateStruct":261,"leadSponsor":262,"locationsCount":46},"100628349","pilot-study-of-an-extended-cbt-group-intervention-for-intolerance-of-uncertainty-100628349","NCT07460479","Pilot Study of an Extended CBT Group Intervention for Intolerance of Uncertainty","Efficacy of an Extended Cognitive-Behavioral Group Psychotherapy Targeting Intolerance of Uncertainty From an Ecological Systems Theory Perspective","Inclusion Criteria:\n\n* Be an undergraduate\u002Fgraduate student (including preparatory class)\n* Experience difficulties related to uncertainty\n* Be between the ages of 18 and 29\n* Have sufficient proficiency in reading, writing, and speaking Turkish\n\nExclusion Criteria:\n\n* Being 29 years of age or older,\n* Having schizophrenia, other psychotic disorders, alcohol and substance use disorders\n* Individuals experiencing severe depression symptoms who require additional intervention to engage in the group process\n* Individuals with cognitive impairment","29 Years",{"count":249,"type":22},15,[25],"This study will examine the effect of cognitive-behavioral group psychotherapy, structured within the framework of ecological systems theory, on adults' intolerance of uncertainty.",[253],"Anxiety",[255,256,257],"intolerance of uncertainty","ecological systems theory","cognitive behavioural group therapy",{"date":233,"type":38},{"date":260,"type":22},"2026-03-04",{"date":66,"type":22},{"name":44,"class":45},{"id":264,"slug":265,"hasResults":12,"nctId":266,"briefTitle":267,"officialTitle":268,"acronym":4,"eligibilityCriteria":269,"healthyVolunteers":12,"sex":189,"minAge":106,"maxAge":107,"enrollmentInfo":270,"targetDuration":4,"studyType":23,"phases":272,"briefSummary":273,"conditions":274,"keywords":276,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":282,"lastUpdatePostDateStruct":283,"startDateStruct":285,"completionDateStruct":287,"leadSponsor":289,"locationsCount":46},"100624844","self-myofascial-release-plus-exercise-versus-exercise-alone-in-type-2-diabetes-100624844","NCT07414914","Self-Myofascial Release Plus Exercise Versus Exercise Alone in Type 2 Diabetes","The Effect of the Addition of Myofascial Release to Exercise Program on Foot Function, Physical Performance, and Plantar Fascia Thickness in Individuals With Type 2 Diabetes: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Individuals aged 30 to 65 years\n* Diagnosed with type 2 diabetes mellitus for at least 1 year\n* Controlled type 2 diabetes mellitus\n* Able to ambulate independently without assistive devices\n\nExclusion Criteria:\n\n* Severe pes planus or pes cavus defined by the Foot Posture Index-6 (FPI-6) (score ≥ +10 or ≤ -5)\n* History of plantar fasciitis\n* Plantar fascia ulceration\n* Peripheral neuropathy\n* Diagnosed peripheral vascular disease\n* History of lower extremity surgery or fracture during last year\n* Rheumatologic or connective tissue disorders affecting soft tissue properties\n* Neurological or diagnosed cognitive disorders\n* Pregnancy\n* Other types of diabetes mellitus\n* Obesity (BMI \\> 30 kg\u002Fm²)\n* Serious cardiopulmonary disorders, including heart failure, history of myocardial infarction, or severe chronic obstructive pulmonary disease or asthma",{"count":271,"type":22},40,[25],"This randomized controlled trial aims to investigate the effects of adding self-myofascial release applied to the plantar fascia and gastrosoleus muscles to an exercise program on foot function, physical performance, and plantar fascia thickness in individuals with type 2 diabetes. Participants aged 30 to 65 years with controlled type 2 diabetes will be randomly allocated to either an exercise-only group or an exercise plus self-myofascial release group. Both groups will complete an eight-week supervised exercise program three times per week. The intervention group will additionally perform self-myofascial release using a foam roller before exercise sessions. Outcomes will include foot function, balance, functional mobility, gait performance, and plantar fascia thickness assessed by ultrasonography before and after the intervention.",[275],"Type 2 Diabetes",[277,278,279,280,281],"Exercise therapy","Self-myofascial release","Physical performance","Foot function","Plantar fascia","2026-02-11",{"date":284,"type":38},"2026-02-17",{"date":286,"type":38},"2025-11-03",{"date":288,"type":22},"2026-05-04",{"name":44,"class":45},{"id":291,"slug":292,"hasResults":12,"nctId":293,"briefTitle":294,"officialTitle":295,"acronym":4,"eligibilityCriteria":296,"healthyVolunteers":12,"sex":189,"minAge":18,"maxAge":107,"enrollmentInfo":297,"targetDuration":4,"studyType":23,"phases":299,"briefSummary":300,"conditions":301,"keywords":307,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":312,"lastUpdatePostDateStruct":313,"startDateStruct":315,"completionDateStruct":317,"leadSponsor":319,"locationsCount":46},"100619209","effect-of-cuff-pressure-assessment-methods-on-postoperative-complications-in-breast-surgery-100619209","NCT07341646","Effect of Cuff Pressure Assessment Methods on Postoperative Complications in Breast Surgery","The Effect of Endotracheal Tube Cuff Pressure Assessment Methods on Postoperative Complications in Patients Undergoing Elective Breast Surgery: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Female patients aged 18 to 65 years.\n* Patients classified as American Society of Anesthesiologists (ASA) physical status I, II, or III.\n* Patients scheduled for elective breast surgery requiring general anesthesia and endotracheal intubation.\n* Patients who provide voluntary written informed consent to participate.\n\nExclusion Criteria:\n\n* Patients with a history of Chronic Obstructive Pulmonary Disease (COPD) or an asthma attack within the last 6 months.\n* Presence of preoperative sore throat, hoarseness, or cough.\n* Patients with predicted difficult intubation or those who are difficult to intubate.\n* Patients with communication difficulties that prevent accurate assessment of symptoms.\n* Patients whose surgery duration exceeds 3 hours.\n* Patients older than 65 years.",{"count":298,"type":22},90,[25],"Endotracheal intubation is a standard procedure used to secure the airway during general anesthesia. A key component of the breathing tube is the \"cuff,\" a balloon-like device that is inflated to seal the airway and prevent aspiration. However, if the pressure within this cuff is too high, it can restrict blood flow to the tracheal lining, leading to complications such as postoperative sore throat, hoarseness, and difficulty swallowing (dysphagia).\n\nCurrently, there are various methods to monitor and adjust this pressure. In many clinical practices, the pressure is adjusted subjectively or checked only once at the beginning of the surgery. These methods may allow pressure to exceed safe limits (typically 20-30 cmH₂O) or fluctuate during the procedure, potentially causing tissue irritation. This randomized controlled trial aims to compare three different methods of assessing and maintaining endotracheal tube cuff pressure to determine which is most effective at reducing postoperative complications. The study focuses on women undergoing elective breast surgery, a group chosen because the surgery typically lasts 1-3 hours and does not involve major changes in head and neck position, allowing for a clear assessment of the cuff pressure methods.\n\nParticipants will be randomly assigned to one of three groups:\n\n* Continuous Monitoring Group: Cuff pressure is monitored continuously using a pressure indicator and maintained within the 20-30 cmH₂O range throughout the surgery.\n* Manometer Group: Cuff pressure is measured and set to 20-30 cmH₂O using a manual manometer once, immediately after intubation.\n* Control Group (Minimal Occlusive Volume): The cuff is inflated with the minimum amount of air required to prevent an air leak, without using a pressure gauge.\n\nResearchers will assess patients for sore throat, cough, hoarseness, and swallowing difficulties at 0, 1, 12, and 24 hours after surgery to identify the safest and most comfortable method for airway management.",[302,303,304,305,306],"Airway Complications","Postoperative Sore Throat","Hoarseness","Dysphagia","Cough Severity",[308,309,310,303,302,311],"Continuous Cuff Pressure Monitoring","Manometer","Endotracheal Tube Cuff Pressure","Intubation Safety","2026-01-14",{"date":314,"type":38},"2026-01-15",{"date":316,"type":22},"2026-03-01",{"date":318,"type":22},"2027-06-01",{"name":44,"class":45},{"id":321,"slug":322,"hasResults":12,"nctId":323,"briefTitle":324,"officialTitle":325,"acronym":4,"eligibilityCriteria":326,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":327,"targetDuration":329,"studyType":330,"phases":4,"briefSummary":331,"conditions":332,"keywords":336,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":343,"lastUpdatePostDateStruct":344,"startDateStruct":346,"completionDateStruct":348,"leadSponsor":350,"locationsCount":46},"100604495","correlation-between-carotid-stump-pressure-and-interhemispheric-rso-asymmetry-during-awake-carotid-endarterectomy-100604495","NCT07150260","Correlation Between Carotid Stump Pressure and Interhemispheric rSO₂ Asymmetry During Awake Carotid Endarterectomy","Evaluation of the Correlation Between Carotid Stump Pressure and Interhemispheric rSO₂ Asymmetry in Awake Carotid Endarterectomy: A Prospective Cohort Study","Inclusion Criteria:\n\n* Adults aged 18 years or older\n* Scheduled for elective carotid endarterectomy (CEA)\n* Able to tolerate surgery under regional anesthesia (superficial cervical plexus block)\n* Availability of bilateral regional cerebral oxygen saturation (rSO₂) measurements by near-infrared spectroscopy (NIRS)\n* Successful intraoperative carotid stump pressure (SP) measurement after cross-clamping\n* Provided written informed consent\n\nExclusion Criteria:\n\n* Incomplete NIRS or SP recordings\n* Conversion from regional to general anesthesia\n* Intraoperative technical complications preventing monitoring\n* History of prior ipsilateral carotid endarterectomy or carotid artery stenting\n* Recent major stroke with permanent neurological deficit\n* Recent myocardial infarction within the past 3 months\n* History of traumatic brain injury within the past 6 months",{"count":328,"type":22},60,"30 Days","OBSERVATIONAL","This study aims to better understand how well the brain is perfused (supplied with blood and oxygen) during a specific type of surgery called carotid endarterectomy (CEA), which is performed to prevent strokes in people with stenosis of carotid arteries.\n\nDuring this surgery, the surgeon temporarily clamps the carotid artery to remove a blockage, which can reduce blood flow to the brain. Monitoring brain oxygen levels during this time is important to prevent brain injury. Two common monitoring methods are:\n\nStump pressure (SP) - a pressure measurement taken from the carotid artery during surgery.\n\nNear-infrared spectroscopy (NIRS) - a non-invasive technique that tracks brain oxygen levels in real time.\n\nThis study focuses on the relationship between carotid stump pressure and differences in brain oxygenation between the two sides of the brain (interhemispheric asymmetry), as measured by NIRS.\n\nThe study will include patients undergoing awake CEA (under regional anesthesia) at a single center university hospital. Oxygen levels in both hemispheres of the brain will be monitored before and after the carotid artery is clamped after 3 minutes. Stump pressure will also be measured. The researchers will examine whether low stump pressure is linked to greater differences in brain oxygen levels between the two sides.\n\nThe primary goal is to determine whether a large difference in brain oxygenation between the two hemispheres (greater than 10%) is associated with low carotid stump pressure. Secondary goals include identifying a stump pressure threshold that predicts significant asymmetry and analyzing the influence of patient and surgical factors.\n\nThe findings may help improve how surgeons and anesthesiologists monitor and protect the brain during CEA, particularly in patients who are awake and can be observed for neurological changes.",[333,334,335],"Carotid Artery Stenosis Symptomatic","Carotid Endarterectomy (CEA) Surgical Patients","Cerebral Hypoperfusion",[337,338,339,340,341,342],"Carotid stump pressure","Near-infrared spectroscopy","rSO₂ asymmetry","Cerebral oxygenation","Awake carotid endarterectomy","Regional anesthesia","2026-01-06",{"date":345,"type":38},"2026-01-07",{"date":347,"type":38},"2025-09-01",{"date":349,"type":22},"2026-10-01",{"name":44,"class":45},{"id":352,"slug":353,"hasResults":12,"nctId":354,"briefTitle":355,"officialTitle":356,"acronym":4,"eligibilityCriteria":357,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":358,"targetDuration":360,"studyType":330,"phases":4,"briefSummary":361,"conditions":362,"keywords":367,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":373,"lastUpdatePostDateStruct":374,"startDateStruct":376,"completionDateStruct":378,"leadSponsor":379,"locationsCount":46},"100616365","comparison-of-ppv-and-lvot-vti-during-passive-leg-raising-to-predict-fluid-responsiveness-100616365","NCT07304661","Comparison of PPV and LVOT VTI During Passive Leg Raising to Predict Fluid Responsiveness","Comparison of Pulse Pressure Variation and LVOT VTI-Based Cardiac Output Changes During Passive Leg Raising Maneuver in Predicting Fluid Responsiveness in Mechanically Ventilated Critically Ill Patients: A Prospective Observational Study","Inclusion Criteria:\n\n1. Adult patients aged ≥18 years\n2. Patients admitted to the intensive care unit receiving mechanical ventilation\n3. Presence of suspected intravascular fluid deficit (hypotension, negative fluid balance, or clinical signs of peripheral hypoperfusion)\n4. Patients in sinus rhythm\n5. Presence of invasive arterial blood pressure monitoring\n6. Adequate echocardiographic window allowing transthoracic echocardiographic measurement of LVOT VTI\n7. Patients ventilated with tidal volume ≥8 mL\u002Fkg (ideal body weight)\n8. Hemodynamically stable enough to allow measurement\n\nExclusion Criteria:\n\n1. Patients under 18 years of age\n2. Presence of atrial fibrillation or significant arrhythmias such as frequent ventricular or atrial ectopy\n3. Severe right ventricular dysfunction or significant tricuspid regurgitation\n4. Advanced aortic valve disease (severe stenosis or severe regurgitation)\n5. Patients with significant spontaneous breathing effort\n6. Patients receiving lung-protective low tidal volume ventilation strategy (\\\u003C8 mL\u002Fkg) due to ARDS\n7. Inadequate echocardiographic window for LVOT VTI assessment\n8. Severe hemodynamic instability during measurement (sudden vasopressor escalation or need for resuscitation)\n9. Patients who refuse to participate or from whom written informed consent cannot be obtained from themselves or a first-degree relative",{"count":359,"type":22},48,"1 Day","Hemodynamic instability remains one of the leading causes of morbidity and mortality among critically ill patients in intensive care units. One major contributor to this instability is intravascular fluid deficit. Although fluid administration is often preferred as an initial intervention, inaccurate estimation of fluid requirements carries significant risks. Inadequate resuscitation may lead to tissue hypoperfusion and organ dysfunction, whereas excessive fluid loading is associated with pulmonary edema, increased intra-abdominal pressure, multi-organ dysfunction, and increased mortality. Consequently, reliable prediction of fluid responsiveness is considered a critical determinant in modern intensive care management.\n\nThe limited reliability of static parameters in predicting fluid responsiveness and the fact that PPV retains its validity only under specific clinical conditions highlight the need for more effective methods. In recent years, hemodynamic changes assessed during the passive leg raising (PLR) maneuver have gained prominence; particularly, left ventricular outflow tract velocity time integral (LVOT VTI)-based cardiac output measurements have been identified as a strong parameter for predicting fluid responsiveness . Moreover, changes in pulse pressure variation (PPV) during PLR have also been reported as a potential predictor; however, the number of studies prospectively comparing PPV variation and LVOT VTI-based cardiac output change within the same patient population remains limited . Therefore, the proposed study aims to fill this gap in the literature and contribute to fluid management in the intensive care setting.\n\nThe aim of this study is to compare the performance of PPV variation and LVOT VTI-based cardiac output change after the PLR maneuver in predicting fluid responsiveness among mechanically ventilated critically ill patients, and to determine the diagnostic value of both methods. The findings of the present study are expected to support more reliable decision-making in fluid therapy and provide clinical evidence toward the individualization of fluid management in intensive care practice.",[363,364,365,366],"Hemodynamic Instability","Hypovolemia","Critical Illness","Pulse Pressure Variation",[368,369,366,370,371,372],"Fluid Responsiveness","Passive Leg Raising","LVOT VTI","Cardiac Output","Echocardiography","2025-12-13",{"date":375,"type":38},"2025-12-26",{"date":377,"type":22},"2026-01-01",{"date":318,"type":22},{"name":44,"class":45},{"id":381,"slug":382,"hasResults":12,"nctId":383,"briefTitle":384,"officialTitle":385,"acronym":4,"eligibilityCriteria":386,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":387,"targetDuration":360,"studyType":330,"phases":4,"briefSummary":389,"conditions":390,"keywords":392,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":373,"lastUpdatePostDateStruct":397,"startDateStruct":398,"completionDateStruct":399,"leadSponsor":401,"locationsCount":46},"100616364","role-of-end-tidal-co2-during-passive-leg-raising-to-predict-fluid-responsiveness-in-icu-100616364","NCT07304648","Role of End-Tidal CO2 During Passive Leg Raising to Predict Fluid Responsiveness in ICU","The Role of End-Tidal Carbon Dioxide Changes During Passive Leg Raising in Predicting Fluid Responsiveness for Mechanically Ventilated Patients in the Intensive Care Unit: A Prospective Observational Study","Inclusion Criteria:\n\n* Patients aged 18 years or older.\n* Patients who have been followed in the intensive care unit (ICU) with mechanical ventilation support for at least 24 hours.\n* Patients for whom a mini fluid challenge (MFC) is clinically planned by the intensive care team.\n* Patients for whom informed consent has been obtained from first-degree relatives or a legal representative.\n\nExclusion Criteria:\n\n* Patients younger than 18 years of age.\n* Pregnant patients.\n* Patients without consent from first-degree relatives or a legal representative.\n* Patients with known deep vein thrombosis (DVT) in the leg veins (risk of embolism during leg raising).\n* Patients with pathologies that may cause increased intracranial pressure (e.g., intracranial mass, hemorrhage).\n* Patients with uncontrolled hypertension.\n* Patients with severe cardiac disease (e.g., right heart failure, pulmonary hypertension, advanced valvular pathology).\n* Patients with carbon dioxide (CO2) retention.\n* Patients who have undergone hip surgery or hip replacement surgery where Passive Leg Raising (PLR) cannot be performed.\n* Patients with spontaneous breathing.\n* Patients with a probability of high intra-abdominal pressure.\n* Patients who cannot lie in a supine position.\n* Patients with current peripheral oxygen saturation (SpO2) \\\u003C 88%.\n* Patients on mechanical ventilation requiring pressure support \\> 16 mmHg or PEEP \\> 10 mmHg.",{"count":388,"type":22},68,"This prospective observational study evaluates whether monitoring changes in exhaled carbon dioxide (End-Tidal CO2 or EtCO2) during a \"Passive Leg Raising\" (PLR) test can reliably predict fluid responsiveness in critically ill patients.\n\nIn the Intensive Care Unit (ICU), fluid management is a critical balance; while fluid is necessary for tissue perfusion, overload can lead to severe complications. Traditional static measurements (like central venous pressure) are often unreliable for guiding therapy. Dynamic tests like PLR are preferred as they simulate a fluid bolus reversibly by shifting blood from the legs to the heart.\n\nResearchers will observe mechanically ventilated patients planned for fluid resuscitation. The study compares the accuracy of non-invasive EtCO2 changes during PLR against a reference standard \"Mini Fluid Challenge\" (100 mL fluid administration). Fluid responsiveness will be confirmed using echocardiographic measurements (LVOT-VTI) or arterial pressure changes. The goal is to validate EtCO2 as a practical, real-time tool for safe fluid management.",[391,365,364],"Circulatory Failure",[368,369,393,394,395,396],"End-Tidal CO2","Mini Fluid Challenge","Mechanical Ventilation","Intensive Care",{"date":375,"type":38},{"date":377,"type":22},{"date":400,"type":22},"2027-07-01",{"name":44,"class":45},{"id":403,"slug":404,"hasResults":12,"nctId":405,"briefTitle":406,"officialTitle":407,"acronym":4,"eligibilityCriteria":408,"healthyVolunteers":12,"sex":17,"minAge":409,"maxAge":18,"enrollmentInfo":410,"targetDuration":4,"studyType":23,"phases":412,"briefSummary":413,"conditions":414,"keywords":4,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":416,"lastUpdatePostDateStruct":417,"startDateStruct":419,"completionDateStruct":421,"leadSponsor":423,"locationsCount":424},"100533375","schroth-and-pilates-exercises-in-idiopathic-adolescent-scoliosis-100533375","NCT06224998","Schroth and Pilates Exercises in Idiopathic Adolescent Scoliosis","Comparison of the Effects of Schroth and Pilates Exercises on Respiratory Functions, Functional Capacity, Balance, Spine Structure and Quality of Life in Idiopathic Adolescent Scoliosis","Inclusion Criteria:\n\n* having a Cobb angle between 10 and 25 degrees\n* age between 10-18 years\n\nExclusion Criteria:\n\n* Presence of secondary scoliosis (congenital, muscular and neurological scoliosis)\n* Presence of any cardiovascular and pulmonary disease that will prevent respiratory functions\n* Having a history of thoracic surgery\n* Use of assistive devices\n* Presence of a secondary orthopedic problem","10 Years",{"count":411,"type":22},30,[25],"Adolescent idiopathic scoliosis (AIS) is a common anomaly that is frequently seen in prepubertal growth and is characterized by deviation and rotation of the spine, causing high level of disability. Pubertal development and asymmetrical load distribution increase the progression of the deformity. Affecting the spinal structure and its movement can affect the structures and cause problems in many areas such as pain, balance, respiration, mental health and quality of life. AIS can cause functional disability by causing deterioration in chest wall mechanics, weakness in respiratory muscles and limitation of functional capacity. As the disease progresses, prolonged hypoinflation and atelectasis lead to irreversible atrophy of the lungs and further reduction in lung volume. Displacement and\u002For compression of the heart due to thoracic deformity may not allow for the required increase in stroke volume during exercise. In severe cases, patients are at risk of developing pulmonary hypertension due to chronic respiratory failure and chronic atelectasis, chronic hypoxemia, chronic hypercapnia. In addition, muscle atrophy and muscle weakness in AIS are thought to cause muscle imbalances and loss of balance.\n\nExercise is the most appropriate treatment for low and moderate AIS cases due to its low cost and low risk of complications. Exercises prevent the development of many problems by controlling the severity of curvature and preventing the progression of curvature. It is thought that scoliosis exercises\n\ncan delay or even prevent surgery and reduce the duration or degree of brace, especially in patients with low-to-moderate curvature during growth. One of these exercise approaches, the Schroth technique, is primarily based on isometric muscle contraction exercises that aim to rotate, lengthen and stabilize the spine. The core component of the Schroth method is autocorrection, defined as the patient's ability to reduce spinal deformity through active postural realignment of the spine in three dimensions.\n\nAnother frequently used exercise method, Pilates exercise training improves flexibility and overall physical health by emphasizing the coordination of movements associated with strength, posture, and breathing. However, the effects of these exercises in reducing curvature and related problems are controversial in the literature. Therefore, in this study, we aimed to investigate the effects of Schroth and pilates exercises on respiratory functions, functional capacity, balance, spine structure and quality of life in adolescents with idiopathic scoliosis.\n\nThirty patients aged 10 to 18 years, with a Cobb angle between 10 and 25 degrees, will be included in the study. The subjects will be randomly divided into two groups; Schroth exercises will be applied to one group and pilates exercises will be applied to another group. All participants will participate in exercise sessions of 60 minutes a day, 3 days a week, for 8 weeks. Each participant will receive a total of 24 sessions of exercise therapy under the supervision of a physiotherapist. In this study, exercises that activate the muscle groups responsible for maintaining the correct posture and correcting the curvature will be selected for practice. Within the study, axial trunk rotation with a scoliometer, respiratory functions and respiratory muscle strength measurement with spirometry, functional capacity with the 6-minute walking test, balance with the Tecnobody balance measuring device, quality of life with Scoliosis will be assessed by the Research Society-22 Quality of Life Questionnaire. The results obtained from the study are of great importance as they will help to determine the effects of Schroth and pilates exercises on spinal deformity and the treatment of related problems in patients with AIS and to establish appropriate programs for the prevention and treatment of these problems.",[415],"Adolescent Idiopathic Scoliosis","2025-06-18",{"date":418,"type":38},"2025-06-24",{"date":420,"type":38},"2023-11-01",{"date":422,"type":22},"2025-08",{"name":44,"class":45},2,{"id":426,"slug":427,"hasResults":12,"nctId":428,"briefTitle":429,"officialTitle":430,"acronym":4,"eligibilityCriteria":431,"healthyVolunteers":12,"sex":17,"minAge":432,"maxAge":18,"enrollmentInfo":433,"targetDuration":4,"studyType":330,"phases":4,"briefSummary":435,"conditions":436,"keywords":439,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":445,"lastUpdatePostDateStruct":446,"startDateStruct":448,"completionDateStruct":450,"leadSponsor":452,"locationsCount":46},"100580411","the-effect-of-two-different-bathing-methods-on-vital-signs-and-comfort-in-picubath-trial-100580411","NCT06836947","The Effect of Two Different Bathing Methods on Vital Signs and Comfort in PICU:Bath Trial","The Effect of Two Different Bathing Methods on Vital Signs and Comfort in Pediatric Intensive Care Unit:Bath Trial","Inclusion Criteria:\n\n1. Being hospitalized in Behçet Uz Pediatric Intensive Care Unit\n2. No contraindications to bathing\n3. Parent's willingness to participate in the study\n\nExclusion Criteria:\n\n1. Having a contraindication to bathing\n2. Parents were not willing to participate in the study","28 Days",{"count":434,"type":22},52,"The study was planned to be conducted and completed within 6 months after ethics committee approval was obtained. The study is a prospective, quasi-experimental study.\n\nThe population of the study will consist of children who are hospitalized in the Pediatric Intensive Care Unit of SBÜ. İzmir Dr. Behçet Uz Pediatric Diseases and Surgery Training and Research Hospital. The vital signs and comfort of the children of the parents who agreed to participate in the study will be measured before bathing (baseline) and care will be taken to ensure that they are similar in both groups.\n\nChildren in the study will not be randomized. In the routine operation of the clinic, traditional bathing is performed once a week and wipe bathing is performed once every two days. Wipe bathing is performed at 36-37 degrees water with 10 ml of chlorhexidine in 200 ml of water. Traditional bathing is also performed with 36-37 degrees water in bed or in the bathtub. In the study, no intervention will be performed and the outcomes will be measured and compared with each other before and after both bathing procedures.\n\nPhysiologic parameters including respiratory rate, pulse rate, oxygen saturation and comfort levels of newborns just before, during and after the bathing process (1st and 5th minute) will be evaluated and compared with each other. To avoid bias in the study, all bathing procedures will be performed by Specialist Nurse Esat Erdem GÖKPINAR.\n\nTranslated with DeepL.com (free version)",[437,438],"Vital Sign Monitoring","Comfort",[440,441,442,443,444],"pediatrics","bath","nursing care","vital signs","comfort","2025-05-05",{"date":447,"type":38},"2025-05-07",{"date":449,"type":38},"2025-04-09",{"date":451,"type":22},"2025-05-30",{"name":44,"class":45},{"id":454,"slug":455,"hasResults":12,"nctId":456,"briefTitle":457,"officialTitle":458,"acronym":4,"eligibilityCriteria":459,"healthyVolunteers":105,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":460,"targetDuration":4,"studyType":330,"phases":4,"briefSummary":461,"conditions":462,"keywords":4,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":467,"lastUpdatePostDateStruct":468,"startDateStruct":469,"completionDateStruct":471,"leadSponsor":473,"locationsCount":46},"100589976","assessment-of-salivary-gm-csf-mip-and-il-1-levels-in-subjects-with-varying-periodontal-conditions-100589976","NCT06961409","Assessment of Salivary GM-CSF, MIP, and IL-1β Levels in Subjects With Varying Periodontal Conditions","Evaluation of Salivary Granulocyte-Macrophage Colony-Stimulating Factor, Macrophage Inflammatory Protein and Interleukin-1β Levels in Individuals With Different Periodontal Conditions","Inclusion Criteria:\n\n* Systemically healthy participants.\n* At least twenty permanent teeth present in the oral cavity.\n* Non-smokers.\n* No medication for continuous use.\n* Not pregnant or breastfeeding.\n\nExclusion Criteria:\n\n* Any oral or systemic disease.\n* Regular use of systemic medications.\n* Pregnancy or lactation.\n* Received periodontal treatment within the last 6 months.\n* Use of antibiotics, anti-inflammatory medications, or systemic corticosteroids in the last 6 months.\n* Smokers.",{"count":328,"type":22},"In order to determine the pathogenesis of chronic inflammatory diseases, the levels of various cytokines are examined in tissues and fluids taken from the body. In recent publications, the role of Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF), Macrophage Inflammatory Protein (MIP)-1α and Interleukin (IL)-1β on chronic inflammatory diseases has been investigated. The aim of this study was to evaluate the levels of these cytokines in the saliva of healthy individuals with gingivitis and periodontitis.\n\nAll oral clinical parameters of 60 systemically healthy individuals (20 healthy, 20 with gingivitis and 20 with periodontitis) who applied to our clinic for routine periodontal control will be measured and saliva samples will be taken from the patients. GM-CSF, MIP-1α and IL-1β (biomarkers emphasizing inflammation in saliva samples) will be determined by enzyme-linked immunoassay (ELISA). Then, statistical analyses will be performed to interpret the difference in cytokine levels between the groups and the relationship between these cytokines and clinical parameters.\n\nPossible significant differences in cytokine levels will reveal that these proteins and enzymes can be utilized as a diagnostic tool in periodontal diseases, to distinguish periodontal disease status from healthy, or as a guide for treatments.",[463,464,465,466],"Periodontal Diseases","Periodontitis","Gingivitis","Periodontal Health","2025-04-29",{"date":447,"type":38},{"date":470,"type":38},"2024-08-14",{"date":472,"type":22},"2025-10-01",{"name":44,"class":45},{"id":475,"slug":476,"hasResults":12,"nctId":477,"briefTitle":478,"officialTitle":478,"acronym":4,"eligibilityCriteria":479,"healthyVolunteers":12,"sex":17,"minAge":480,"maxAge":481,"enrollmentInfo":482,"targetDuration":4,"studyType":330,"phases":4,"briefSummary":484,"conditions":485,"keywords":489,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":492,"lastUpdatePostDateStruct":493,"startDateStruct":494,"completionDateStruct":496,"leadSponsor":498,"locationsCount":4},"100567445","the-effect-of-parental-presence-on-the-childs-comfort-and-physiologic-parameters-in-picu-100567445","NCT06668285","The Effect of Parental Presence on the Child's Comfort and Physiologic Parameters in PICU","Inclusion Criteria\n\n1. Being hospitalized in Behçet Uz Pediatric Intensive Care Unit\n2. Parent's volunteering to participate in the study Exclusion Criteria\n\n1\\. Any intervention by the child's parent that may affect the dependent variables (watching cartoons, listening to music, etc.)","0 Years","3 Years",{"count":483,"type":22},50,"The study was planned to be conducted and completed within 6 months after ethics committee approval was obtained. The research is a prospective, quasi-experimental study.\n\nThe population of the study will consist of children hospitalized in the Pediatric Intensive Care Unit of SBU, Izmir Dr. Behçet Uz Pediatric Diseases and Surgery Training and Research Hospital. Randomization of children will be done to determine which children's data will be followed on the relevant visit day.\n\nPhysiologic parameters including respiratory rate, pulse rate, oxygen saturation, body temperature, blood pressure and comfort levels of the children will be evaluated just before, during and after the parental visit (1st minute and 5th minute) and compared with those before the parental visit. All observations will be made by the same nurse to avoid bias in the study.",[486,438,487,488],"Family Centered Care","Vital Sign Evaluation","Parent",[490,491,444,443],"family centered care","parents presence","2025-04-05",{"date":449,"type":38},{"date":495,"type":22},"2025-04-15",{"date":497,"type":22},"2025-07",{"name":44,"class":45},{"id":500,"slug":501,"hasResults":12,"nctId":502,"briefTitle":503,"officialTitle":504,"acronym":4,"eligibilityCriteria":505,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":107,"enrollmentInfo":506,"targetDuration":4,"studyType":23,"phases":507,"briefSummary":508,"conditions":509,"keywords":513,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":519,"lastUpdatePostDateStruct":520,"startDateStruct":522,"completionDateStruct":523,"leadSponsor":525,"locationsCount":46},"100573487","intermittent-theta-burst-stimulation-in-fibromyalgia-syndrome-100573487","NCT06746922","Intermittent Theta Burst Stimulation in Fibromyalgia Syndrome","The Effect of Intermittent Theta Burst Stimulation to the Primary Motor Cortex on Pain Intensity, Pain Catastrophizing, Quality of Life and Mood in Fibromyalgia Patients","Inclusion Criteria:\n\n* Being between the ages of 18-65\n* Being diagnosed with fibromyalgia syndrome (according to 2016 criteria)\n* Average pain intensity of NRS ≥ 4\u002F10\n* Fibromyalgia treatment was stable for the last 3 months and no treatment change was planned during the study\n\nExclusion Criteria:\n\n* Having a clinical condition that would constitute a contraindication for TMS (metallic implant, cardiac pacing, pregnancy, epilepsy, head trauma, history of cranial operation...)\n* Presence of malignancy\n* Systemic rheumatologic diseases\n* Major orthopedic problems limiting activities of daily living (gait disturbance or fracture sequelae limiting joint mobility, prostheses, nerve-tendon injuries)\n* Serious neurological diseases (increased intracranial pressure, presence of space-occupying lesions in the brain, history of epilepsy, presence of cerebral aneurysm, Parkinson's disease, Huntington's chorea, multiple sclerosis, history of previous head trauma causing loss of consciousness)\n* Alcohol or drug addiction\n* History of major depression\u002Fpersonality disorder or psychosis\n* Having received TMS treatment before\n* Taking benzodiazepine, gabapentin\u002Fpregabalin or anticonvulsant medications that have the potential to interfere with intermittent theta burst stimulation treatment or have taken them within the last 4 weeks\n* Pregnant or planning pregnancy or breastfeeding",{"count":411,"type":22},[25],"Research on repetitive transcranial magnetic stimulation therapy in fibromyalgia syndrome (FMS) is increasing rapidly. High-frequency rTMS administration to FMS patients is reported to restore intracortical facilitation and provide successful pain relief. This finding supports restoration of cortical stimulation as one of the possible mechanisms of action for rTMS. One treatment protocol is intermittent theta burst stimulation (iTBS, a variant of excitatory rTMS). Although there are many treatment protocols, there are few widely accepted treatment schemes in the literature. In fibromyalgia syndrome, there is no study in the literature. It was planned to include at least 30 patients aged 18-65 years who were admitted to İzmir Katip Çelebi University Atatürk Training and Research Hospital Physical Medicine and Rehabilitation Outpatient Clinic or hospitalized in the ward and diagnosed with fibromyalgia syndrome according to the 2016 criteria. This study has a prospective, parallel group, randomized, sham-controlled study design. A total of 30 fibromyalgia patients will be randomized into 2 groups and will receive a total of 10 sessions of transcranial magnetic stimulation to the primary motor cortex with intermittent theta bust stimulation technique or sham application. Patients will continue their current fibromyalgia treatment.Numeric Rating Scale-pain intensity (NRS-pain), revised Fibromyalgia Impact Questionnaire (FIQR), Pain Catastrophizing Scale (PCS), Hospital Depression Anxiety Scale (HADS) will be used in the evaluation of the patients.",[510,511,512],"Fibromyalgia","Transcranial Magnetic Stimulation Repetitive","Pain",[510,514,515,516,517,518],"intermittent theta burst stimulation","pain","Pain Catastrophizing","Revised Fibromyalgia Impact Questionnaire","Hospital Anxiety and Depression Scale","2025-03-13",{"date":521,"type":38},"2025-03-18",{"date":519,"type":38},{"date":524,"type":22},"2027-04-01",{"name":44,"class":45},{"id":527,"slug":528,"hasResults":12,"nctId":529,"briefTitle":530,"officialTitle":531,"acronym":4,"eligibilityCriteria":532,"healthyVolunteers":105,"sex":17,"minAge":18,"maxAge":533,"enrollmentInfo":534,"targetDuration":4,"studyType":23,"phases":536,"briefSummary":537,"conditions":538,"keywords":541,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":545,"lastUpdatePostDateStruct":546,"startDateStruct":548,"completionDateStruct":550,"leadSponsor":552,"locationsCount":46},"100574516","effect-of-kinesio-taping-on-lumbar-muscle-temperature-100574516","NCT06760299","Effect of Kinesio Taping on Lumbar Muscle Temperature","Investigation of the Effect of Kinesio Taping Applied to Lumbar Paravertebral Muscles Under Different Tensions on Local Body Temperature: a Single-Blind, Randomized Controlled Trial","Inclusion Criteria:\n\n* Willingness to participate in the study\n* Aged between 18 and 35 years\n* Ability to read and understand Turkish\n\nExclusion Criteria:\n\n* Experiencing muscle pain in the upper extremity, torso, or lower extremity\n* Use of medication or having a systemic disease that may affect thermoregulation\n* Having dermatological conditions in the area where Kinesio Taping will be applied\n* Having undergone surgery in the upper extremity, torso, or lower extremity\n* Being pregnant","35 Years",{"count":535,"type":22},54,[25],"This single-blind, randomized controlled trial aims to investigate the effect of Kinesio Taping (KT) applied to lumbar paravertebral muscles with different tensions (25% and 75%) on local body temperature. The study will compare the changes in local body temperature before and after KT application using infrared thermography. Participants will be randomly allocated to one of three groups with randomization stratified by sex: 25% tension KT, 75% tension KT, and a control group. Temperature measurements will be taken at four time points: before the application, 15 minutes, 45 minutes, and 24 hours post-application. The data will be analyzed using statistical methods to evaluate the impact of KT tension on local body temperature. This study will provide insights into the physiological effects of KT under different tension levels.",[539,540],"Kinesio Taping","Body Temperature Changes",[542,539,543,544],"Thermal Imaging","Body Temperature","Lumbar Muscles","2025-01-20",{"date":547,"type":38},"2025-01-22",{"date":549,"type":22},"2025-01",{"date":551,"type":22},"2025-03",{"name":44,"class":45},{"id":554,"slug":555,"hasResults":12,"nctId":556,"briefTitle":557,"officialTitle":558,"acronym":4,"eligibilityCriteria":559,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":129,"enrollmentInfo":560,"targetDuration":4,"studyType":23,"phases":562,"briefSummary":563,"conditions":564,"keywords":566,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":570,"lastUpdatePostDateStruct":571,"startDateStruct":573,"completionDateStruct":575,"leadSponsor":577,"locationsCount":46},"100576187","the-effect-of-periodontal-dressings-and-various-materials-on-the-donor-sites-quality-of-life-after-free-gingival-graft-surgery-100576187","NCT06782035","The Effect of Periodontal Dressings and Various Materials on the Donor Site's Quality of Life After Free Gingival Graft Surgery","The Influence of Periodontal Dressings (Ora-Aid) and Various Materials on the Donor Site's Quality of Life After Free Gingival Graft Surgery","Inclusion Criteria:\n\nSystemically healthy Non-smoker Insufficient attached gingiva Not using any medication regularly Age 18-85 years No previous graft taken from the same area Not in pregnancy or lactation period Agreement to participate in the study and sign the \"Informed Consent Form\"\n\nExclusion Criteria:\n\nSystemic disease Regular systemic medication use Under 18 years old Pregnant or breastfeeding women Smoker Previous graft taken from the same area",{"count":561,"type":22},36,[25],"The inadequate width of attached gingiva, resulting from the loss of the attached gingiva band, is one of the primary mucogingival issues. Free gingival graft (FGG) is a mucogingival surgical technique used to increase the amount of attached gingiva, cover exposed root surfaces in localized gingival recessions, deepen the vestibule, and eliminate frenulum and muscle attachments. The harvested tissue is keratinized attached gingiva. Due to ease of access, the palate is most commonly preferred as the donor site.\n\nComplications that may arise following FGG surgery are generally donor site-related. Reported complications include postoperative bleeding, recurrent herpetic lesions, delayed healing, paresthesia, mucocele, arteriovenous shunt, and postoperative pain. To aid healing and reduce discomfort and pain associated with the wound site in the palate after surgery, various materials have been applied to the donor site to facilitate recovery.\n\nFollowing FGG surgery, patients will be divided into three groups based on the application of different materials to the wound site in the palate: leukocyte- and platelet-rich fibrin (L-PRF), Ora-Aid oral wound dressing, and a palatal surgical stent. In the Ora-Aid group, after harvesting the graft and placing it in the recipient site, the wound area will be irrigated with saline solution, and Ora-Aid will be trimmed to the appropriate size and shape. It will be gently pressed onto the wound for 5-10 seconds until it adheres. Ora-Aid and L-PRF will be secured to the wound site with a 4\u002F0 silk cross suture. The Ora-Aid application will serve as the test group, the L-PRF application as the positive control group, and the palatal surgical stent as the negative control group. Randomization will be performed using a computer program.\n\nPostoperatively, patients' pain levels will be assessed on the 3rd, 7th, and 14th days using the Visual Analog Scale (VAS) test and the OHIP-14 questionnaire. Wound site epithelialization will be evaluated during follow-up sessions on the 7th and 14th days and at 1 month. After evaluating all questionnaire results, statistical analyses will be conducted.",[565],"Recession, Gingival",[567,568,569],"Free gingival graft","Mucogingival surgery","Periodontal dressing","2025-01-13",{"date":572,"type":38},"2025-01-17",{"date":574,"type":38},"2025-01-02",{"date":576,"type":22},"2025-05-25",{"name":44,"class":45},{"id":579,"slug":580,"hasResults":12,"nctId":581,"briefTitle":582,"officialTitle":583,"acronym":4,"eligibilityCriteria":584,"healthyVolunteers":105,"sex":17,"minAge":18,"maxAge":106,"enrollmentInfo":585,"targetDuration":4,"studyType":23,"phases":586,"briefSummary":587,"conditions":588,"keywords":4,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":590,"lastUpdatePostDateStruct":591,"startDateStruct":593,"completionDateStruct":595,"leadSponsor":596,"locationsCount":46},"100559272","effect-of-different-centrifuge-values-on-saliva-high-sensitive-c-reactive-protein-hs-crp-levels-in-individuals-with-different-smoking-amounts-100559272","NCT06561971","Effect of Different Centrifuge Values on Saliva High Sensitive C-Reactive Protein (Hs-CRP) Levels in Individuals With Different Smoking Amounts","Evaluating the Effect of Smoking Amount on Determining Salivary High Sensitive C-Reactive Protein(Hs-CRP) Values by Centrifuging the Saliva of the Same Individuals at Different Rpm and Time.","Inclusion Criteria:\n\n* Systemically healthy\n* Periodontally clinical healthy\n* At least 20 permanent teeth in the mouth\n* No medication for continuous use\n* Those who have not used antibiotics, anti-inflammatory and systemic corticosteroid drugs in the last 6 months.\n* Not in pregnancy or lactation period.\n* Not received periodontal treatment in the last 6 months\n\n  * For the non-smoker group; person who does not smoke tobacco\n  * For the light-smoker group; person who smokes less than 10 cigarettes a day\n  * For heavy-smoker group; person who smokes more than 10 cigarettes a day\n\nExclusion Criteria:\n\n* Any oral or systemic disease\n* Regularly using a systemic medication\n* During pregnancy or lactation\n* Received periodontal treatment within the last 6 months.\n* Those who received antibiotic, anti-inflammatory or systemic corticosteroid medication in the last 6 months\n* Individual with periodontal disease",{"count":298,"type":22},[25],"The purpose of this study; In periodontally healthy individuals, high sensitive c-reactive protein (hs-CRP) levels of non-smokers, smokers of less than 10 cigarettes per day and smokers of more than 10 cigarettes per day were measured at 15 rpm-10 min, 10 centrifuge values, which are frequently used in saliva studies. To determine the levels in saliva samples as a result of rpm-10 min and 10 rpm 6 min centrifugations and to determine the values at which a cytokine of this molecular weight should be centrifuged and to examine the possible correlation between these values and the clinical parameters of the amount of smoking. Materials and Methods: saliva samples were collected from 90 systemically healthy individuals who were non-smokers (N, n=30), light smokers \\\u003C10 cigarettes per day (L, n=30) and heavy smokers \\>10 cigarettes per day (H, n=20). samples were taken. Full-mouth clinical periodontal measurements, including probing depth (PD), clinical attachment level (CAL), bleeding on probing (BOP), gingival index (GI), and plaque index (PI), were also recorded. Enzyme-linked immunosorbent assay (ELISA) was used to determine hs-CRP levels in biological samples.",[589],"Smoking","2024-12-19",{"date":592,"type":38},"2024-12-20",{"date":594,"type":38},"2024-06-01",{"date":547,"type":22},{"name":44,"class":45},{"id":598,"slug":599,"hasResults":12,"nctId":600,"briefTitle":601,"officialTitle":602,"acronym":4,"eligibilityCriteria":603,"healthyVolunteers":105,"sex":17,"minAge":604,"maxAge":605,"enrollmentInfo":606,"targetDuration":4,"studyType":23,"phases":607,"briefSummary":608,"conditions":609,"keywords":4,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":610,"lastUpdatePostDateStruct":611,"startDateStruct":613,"completionDateStruct":615,"leadSponsor":617,"locationsCount":46},"100530448","evaluation-of-salivary-gal-7-gal-10-and-mmp-9-levels-of-individuals-with-different-periodontal-diseases-100530448","NCT06186908","Evaluation of Salivary Gal-7, Gal-10 and MMP-9 Levels of Individuals With Different Periodontal Diseases","Assessment of Saliva Galectin-7, Galectin-10 and MMP-9 Levels In Individuals With Different Periodontal Diseases","Inclusion Criteria:\n\n* Systemically healthy (The determination of healthy volunteers will be based on the statements of the patients in the anamnesis. No additional examinations will be made.)\n* At least twenty permanent teeth in the mouth\n* Non-smoker\n* No medication for continuous use\n* Those who have not used antibiotics, anti-inflammatory and systemic corticosteroid drugs in the last 6 months.\n* Not in pregnancy or lactation period.\n* For the periodontitis group that has not received periodontal treatment in the last 6 months\n* For the periodontitis group; According to the evaluation made in 6 regions of each tooth, individuals with 30% or more bleeding on probing area, at least 2 teeth not adjacent to each quarter jaw with a depth of 5 mm or more and 4 mm or more attachment loss, coronal 1\u002F3 and more on radiography (horizontal and \u002F or vertical) bone loss\n* For the gingivitis group; According to the evaluation made in 6 regions of each tooth, individuals with 10% or more bleeding on probing area, having a probing depth of less than 4mm and no attachment loss\n* For healthy group; According to the evaluation made in 6 regions of each tooth,individuals with less than 10% bleeding on probing area, having a probing depth less than 4mm and no loss of attachment were included in the study.\n\nExclusion Criteria:\n\n* Any oral or systemic disease\n* Regularly using a systemic medication\n* During pregnancy or lactation\n* Received periodontal treatment within the last 6 months.\n* Those who received antibiotic, anti-inflammatory or systemic corticosteroid medication in the last 6 months\n* Smokers are not included in the study","20 Years","60 Years",{"count":328,"type":22},[25],"The aim of this study is; detection of Galectin-10, Galectin-7, MMP-9 levels in saliva samples of periodontally healthy, gingivitis and periodontitis patients and the possible correlation between these values and clinical parameters of periodontal diseases. Materials and methods: Samples of saliva were obtained from 60 systemically healthy non-smoker individuals with periodontitis (P, n=20), gingivitis(G, n=20) and healthy periodontium (S, n=20). Full-mouth clinical periodontal measurements including probing depth (PD), clinical attachment level (CAL), bleeding on probing (BOP), gingival index (GI) and plaque index (PI) were also recorded. Enzyme-linked immunosorbent assay (ELISA) was used to determine Galectin-10, Galectin-7 and MMP-9 levels in the biological samples.",[463],"2024-10-25",{"date":612,"type":38},"2024-10-28",{"date":614,"type":38},"2024-05-02",{"date":616,"type":22},"2025-03-24",{"name":44,"class":45},{"id":619,"slug":620,"hasResults":12,"nctId":621,"briefTitle":622,"officialTitle":623,"acronym":4,"eligibilityCriteria":624,"healthyVolunteers":12,"sex":17,"minAge":360,"maxAge":432,"enrollmentInfo":625,"targetDuration":4,"studyType":23,"phases":627,"briefSummary":628,"conditions":629,"keywords":631,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":634,"lastUpdatePostDateStruct":635,"startDateStruct":637,"completionDateStruct":639,"leadSponsor":641,"locationsCount":4},"100478535","eras-protocol-in-newborns-cares-study-100478535","NCT05511233","ERAS Protocol in Newborns: CARES Study","OutComes of Implementing EnhAnced Recovery AftEr Intestinal Surgery Protocol in Newborns: CARES Study","Inclusion Criteria:\n\n* Newborns who had intestinal surgery in the Ege University Faculty of Medicine Hospital Neonatal Surgery Intensive Care Unit and\n* whose records can be accessed retrospectively from the electronic health records will be included.\n\nExclusion Criteria:\n\n* Those whose early enteral feeding initiation is contraindicated will not be included in the study.",{"count":626,"type":22},42,[25],"Aim: To determine whether the enteral feeding time and the type of the nutrient (according to the ERAS Recommendations) have any effect on LoS, complications, body weight gain, time until oral feeding, and time until first stool who have undergone intestinal surgery.\n\nDesign: A blinded, retrospective, randomized controlled trial. Setting: One-centred. Participants: Newborns who had intestinal surgery in the Ege University Faculty of Medicine Hospital Neonatal Surgery Intensive Care Unit and whose records can be accessed retrospectively from the electronic health records will be included. Those whose early enteral feeding initiation is contraindicated will not be included in the study.",[630],"Pediatric",[632,633],"pediatric surgery","enhanced recovery","2024-10-21",{"date":636,"type":38},"2024-10-23",{"date":638,"type":22},"2024-11-01",{"date":640,"type":22},"2025-09-30",{"name":44,"class":45},{"id":643,"slug":644,"hasResults":12,"nctId":645,"briefTitle":646,"officialTitle":647,"acronym":4,"eligibilityCriteria":648,"healthyVolunteers":105,"sex":17,"minAge":481,"maxAge":18,"enrollmentInfo":649,"targetDuration":360,"studyType":330,"phases":4,"briefSummary":650,"conditions":651,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":655,"lastUpdatePostDateStruct":656,"startDateStruct":658,"completionDateStruct":660,"leadSponsor":662,"locationsCount":46},"100564252","comparison-of-oxygen-saturation-measurements-using-different-glove-colors-in-children-100564252","NCT06626763","Comparison of Oxygen Saturation Measurements Using Different Glove Colors in Children","Comparison of Oxygen Saturation Measurements Using Different Glove Colors in Children: A Preventive Method for Infection?","Inclusion Criteria:\n\n* Children between the ages of 3-18,\n* The parent\u002Flegal guardian or the child himself\u002Fherself agrees to participate in the study,\n* Arterial blood gas measurement was performed,\n\nExclusion Criteria:\n\n* The finger has a skin condition,\n* Having nail polish on your fingernails,\n* Having a severed finger,",{"count":388,"type":22},"The aim of this study was to determine the effect of different colored gloves on oxygen saturation in pediatric patients whose oxygen saturation was measured by pulse oximetry in pediatric emergency department. The population of the study, which is planned as a prospective cohort study, will consist of children between the ages of 3-18 years who underwent oxygen saturation measurements in the pediatric emergency clinic of İzmir Bakırçay University Cigli and Training and Research Hospital between October 2024 and October 2025.",[652,653,654],"Infection","Oxygen Saturation","Children","2024-10-03",{"date":657,"type":38},"2024-10-04",{"date":659,"type":22},"2024-10-08",{"date":661,"type":22},"2025-10-08",{"name":44,"class":45},""]