[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Józef Piłsudski University of Physical Education\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":123},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,44,76,101],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":24,"conditions":25,"keywords":27,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":4},"100635965","functional-limitations-body-structure-and-function-impairments-and-quality-of-life-in-adults-after-surgical-treatment-of-adolescent-idiopathic-scoliosis-100635965",false,"NCT07559539","Functional Limitations, Body Structure and Function Impairments, and Quality of Life in Adults After Surgical Treatment of Adolescent Idiopathic Scoliosis","Functional Limitations, Body Structure and Function Impairments, and Quality of Life in Adults After Surgical Treatment of Adolescent Idiopathic Scoliosis With Comparison to Non-Operatively Treated and Non-Scoliotic Individuals","AIS","Inclusion Criteria:\n\n* Female, age 25-40\n* AIS diagnosed before age 18 (Cobb angle \\>35°)\n* Operated group: PSF, 10-25 years post-surgery\n* Informed consent\n\nExclusion Criteria:\n\n* Surgery other than PSF\n* Surgery performed in adulthood","FEMALE","25 Years","40 Years",{"count":21,"type":22},90,"ESTIMATED","OBSERVATIONAL","Adolescent idiopathic scoliosis (AIS) is a three-dimensional spinal deformity, and a subset of patients undergo surgical correction during adolescence, most commonly posterior spinal fusion (PSF). Although surgical treatment improves deformity and quality of life in the short and mid-term, its long-term impact on functional status in adulthood remains insufficiently understood.\n\nThis cross-sectional study aims to evaluate long-term outcomes in adults aged 25-40 years who underwent surgical treatment for AIS, compared with non-operated individuals with scoliosis and healthy controls. The study will assess limitations in daily functioning, musculoskeletal and respiratory function, pain, and compensatory mechanisms using standardized clinical measurements and questionnaires.\n\nThe findings are expected to provide insight into long-term functional consequences of AIS and support the development of targeted physiotherapy and preventive strategies for adults treated for scoliosis during adolescence.",[26],"Adolescence Idiopathic Scoliosis",[28,29,30,31],"Adolescent Idiopathic Scoliosis","adult scoliosis","spinal fusion","Long-Term Adverse Effects","NOT_YET_RECRUITING","2026-05-14",{"date":35,"type":36},"2026-05-18","ACTUAL",{"date":38,"type":22},"2026-05-16",{"date":40,"type":22},"2028-08-16",{"name":42,"class":43},"Józef Piłsudski University of Physical Education","OTHER",{"id":45,"slug":46,"hasResults":11,"nctId":47,"briefTitle":48,"officialTitle":49,"acronym":4,"eligibilityCriteria":50,"healthyVolunteers":11,"sex":51,"minAge":52,"maxAge":4,"enrollmentInfo":53,"targetDuration":4,"studyType":55,"phases":56,"briefSummary":58,"conditions":59,"keywords":61,"overallStatus":66,"whyStopped":4,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":75},"100614028","inspiratory-muscle-training-in-patients-with-inflammatory-myopathy-100614028","NCT07274267","Inspiratory Muscle Training in Patients With Inflammatory Myopathy","The Effect of Inspiratory Muscle Training on the Functional Status of Patients With Inflammatory Myopathy","Inclusion Criteria:\n\n* Diagnosis of inflammatory myopathy according to European Alliance of Associations for Rheumatology \u002F American College of Rheumatology criteria\n* Age ≥ 18 years\n* Stable clinical condition allowing participation in physical activity\n* Ability to understand and follow instructions\n* Written informed consent to participate in the study\n\nExclusion Criteria:\n\n* Cognitive impairment preventing proper exercise performance\n* Current respiratory tract infection\n* Previous respiratory muscle training within the last 12 months\n* History of spontaneous pneumothorax\n* Pulmonary hypertension\n* Tympanic membrane rupture or other middle ear pathology\n* Lack of voluntary and informed consent","ALL","18 Years",{"count":54,"type":22},33,"INTERVENTIONAL",[57],"NA","Inflammatory myopathies are rare autoimmune diseases leading to progressive muscle weakness, often including the respiratory muscles. This study aims to investigate whether inspiratory muscle training (IMT) using a threshold device can improve functional status in patients with inflammatory myopathy. Thirty-three patients will undergo a 3-month home-based IMT program with progressive resistance. Functional capacity, inspiratory muscle strength, lung function, diaphragmatic mobility, fatigue, and quality of life will be assessed at baseline and during follow-up. The primary hypothesis is that IMT will enhance inspiratory muscle strength and translate into better functional performance and quality of life.",[60],"Inflammatory Myopathies",[62,63,64,65],"Inspiratory muscle training","Diaphragm ultrasound","Respiratory muscle strength","Exercise tolerance","RECRUITING","2026-02-23",{"date":69,"type":36},"2026-02-25",{"date":71,"type":36},"2024-08-12",{"date":73,"type":22},"2026-12",{"name":42,"class":43},1,{"id":77,"slug":78,"hasResults":11,"nctId":79,"briefTitle":80,"officialTitle":80,"acronym":81,"eligibilityCriteria":82,"healthyVolunteers":83,"sex":51,"minAge":84,"maxAge":4,"enrollmentInfo":85,"targetDuration":4,"studyType":55,"phases":87,"briefSummary":88,"conditions":89,"keywords":4,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":93,"lastUpdatePostDateStruct":94,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":100,"locationsCount":4},"100571493","aquarebal---aquatic-reactive-balance-training-for-older-adults-100571493","NCT06720974","AquaReBal - Aquatic Reactive Balance Training for Older Adults","AquaReBal","Inclusion Criteria:\n\n* 65 years and older\n* able to stand ≥1 min\n* able to independently walk ≥10 m without assistance\n* a history of ≥2 falls in the past 12 months, history of an injurious fall in the past 12 months, and\u002For self-reported balance difficulties\n\nExclusion Criteria:\n\n* Current diagnosis of neurological or sensory disorders\n* uncorrected vision problems\n* recurrent dizziness\n* cognitive deficits\n* medical conditions that could increase injury risk during balance tests (e.g. presence of a prior fragility fracture)\n* conditions that would not allow the participant to get into the therapy pool (e.g. wounds, fear of water)\n* currently attending physiotherapy or supervised exercise.",true,"65 Years",{"count":86,"type":22},15,[57],"Falls are the second leading cause of accidental injury deaths worldwide, mostly in older adults. Injuries resulting from a fall are a leading cause of hospitalizations among older adults in Canada with a higher total injury cost than any other cause of injury. People must often perform rapid and complex movements to keep from falling. Reactive balance training (RBT) is a type of training that focuses on improving an individual's ability to perform those types of movements and respond to unexpected or sudden changes. RBT and aquatic therapy were identified as a research priority for fall prevention. There is evidence that RBT reduces the rate of falls by a half in daily life and improvements in reactive balance are maintained up to a year after the end of the program. When RBT is conducted on land, some adverse events such as fear of falling and joint pain may occur. The water environment could minimize the limitations and barriers associated with land-based RBT. To date, there are no studies showing the effects of water-based RBT on reactive balance control in older adults.The study aims to explore if water-based RBT is a practical intervention to reduce the number of falls in older adults. Older adults will be recruited from the Greater Toronto Area. They will receive training 2 times per week for 6 weeks. The main practical factors around the intervention, such as how participants adhere to the treatment and how they accept the intervention will be measured. It will be assessed how the water-based and land-based RBT affects falls, balance, mobility and quality of life. With this study, the aim is to inform the way for a larger study targeting falls - one of the biggest problems among older adults.",[90,91,92],"Older Adults, Balance","Older People","Aquatic Physical Exercise","2025-09-10",{"date":95,"type":36},"2025-09-16",{"date":97,"type":22},"2025-12",{"date":99,"type":22},"2027-04",{"name":42,"class":43},{"id":102,"slug":103,"hasResults":11,"nctId":104,"briefTitle":105,"officialTitle":106,"acronym":4,"eligibilityCriteria":107,"healthyVolunteers":83,"sex":108,"minAge":52,"maxAge":18,"enrollmentInfo":109,"targetDuration":4,"studyType":55,"phases":111,"briefSummary":112,"conditions":113,"keywords":4,"overallStatus":66,"whyStopped":4,"lastUpdateSubmitDate":115,"lastUpdatePostDateStruct":116,"startDateStruct":118,"completionDateStruct":120,"leadSponsor":122,"locationsCount":75},"100577920","cold-vs-warm-water-immersion-for-doms-recovery-100577920","NCT06804564","Cold Vs Warm Water Immersion for DOMS Recovery","Comparative Effectiveness of Cold and Warm Water Immersion in Mitigating Delayed Onset Muscle Soreness: a Multi-Arm Randomized Controlled Trial","Inclusion Criteria:\n\n* Healthy males aged 18-25 years\n* BMI between 18.5 and 30 kg\u002Fm²\n* Experiencing muscle pain (VAS scale) \\> 5 for muscle soreness within 12 to 30 hours post-exercise\n* Engage in moderate physical activity 2-5 hours\u002Fweek, according to the International Physical Activity Questionnaire-Short Form (IPAQ-SF).\n* They must voluntarily sign a written informed consent approved by an ethics\u002Fbioethics committee after sufficient explanation prior to participating in the study.\n\nExclusion Criteria:\n\n* Inflammatory diseases within the past 6 months\n* Neurological disorders that affect muscle strength\n* Ongoing use of steroids, analgesics, muscle relaxants, or other medications deemed inappropriate by the researchers, including antispasmodics, antidepressants, antidiarrheals, antibiotics, or thrombolytics\n* Unstable medical condition such as cardiovascular disease, respiratory disease, gastrointestinal disease, hepatobiliary disease, metabolic disease, endocrine disease, kidney disease, urinary tract disease, genetic disorders, or issues related to the nervous system or mental health.\n* Participants who have abused alcohol or drugs in the past year, do not wish to follow the study guidelines, or are deemed inappropriate for the study by the researcher will also be excluded.","MALE",{"count":110,"type":22},52,[57],"The study investigates the effectiveness of physical strategies in addressing Delayed Onset Muscle Soreness (DOMS) in physically active individuals. DOMS, a common phenomenon following intense or novel physical activity, is characterized by pain, inflammation, and functional impairments such as reduced range of motion, muscle strength, and endurance. These symptoms peak between 24-72 hours post-exercise and are attributed to micro-damage in muscle and connective tissue, followed by inflammatory responses. Despite extensive research, the efficacy of various therapeutic interventions remains inconclusive due to heterogeneity in study designs, outcome measures, and quality of evidence.\n\nThe primary objective of this study is to systematically assess and compare the effectiveness of cold water immersion (CWI) or hot water immersion (HWI), in mitigating DOMS symptoms. This study will utilize a multi-arm, parallel, randomized controlled trial (RCT) design to evaluate therapeutic outcomes against a control group receiving simulated therapy.\n\nBy employing a standardized exercise protocol to induce DOMS and unified assessment methodologies (e.g., biomechanical, biochemical, and functional tests), the study aims to provide robust evidence for the efficacy of these interventions. The findings will contribute to optimizing post-exercise recovery strategies, offering reliable therapeutic protocols for both clinical and athletic settings.",[114],"Muscle Soreness","2025-02-07",{"date":117,"type":36},"2025-02-11",{"date":119,"type":36},"2025-01-10",{"date":121,"type":22},"2025-03-31",{"name":42,"class":43},""]