[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"JHSPH Center for Clinical Trials\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":74},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,44],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":29,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":43},"100536993","early-intervention-to-promote-cardiovascular-health-of-mothers-and-children-100536993",false,"NCT06272045","Early Intervention to Promote Cardiovascular Health of Mothers and Children","Early Intervention to Promote Cardiovascular Health of Mothers and Children (ENRICH)","ENRICH","Inclusion Criteria:\n\n1. Be currently enrolled in an evidence-based home visiting program participating in ENRICH\n2. Be pregnant, with a single or multifetal gestation, at or less than 34 weeks 0 days gestation (per self-report at time of consent)\n3. Be 18 years of age or older\n4. Speak English or Spanish\n\nExclusion Criteria: There are no exclusion criteria being applied in assessing eligibility for participation in ENRICH.",true,"FEMALE","18 Years",{"count":21,"type":22},6618,"ESTIMATED","INTERVENTIONAL",[25],"NA","Early Intervention to Promote Cardiovascular Health of Mothers and Children (ENRICH) is a cluster randomized clinical trial, funded by the National Heart Lung \\& Blood Institute. The study is designed to test the effectiveness of home visiting intervention to promote cardiovascular health and reduce disparities in maternal and early childhood cardiovascular health. Sites, in partnership with evidence-based home visiting programs, are recruiting 6618 participants in total (i.e., 3309 mother-child dyads which includes 3309 mothers and 3309 children) from diverse community settings with a high burden of cardiovascular disease risk factors.",[28],"Cardiovascular Health",[30],"Home visiting, cardiovascular health, prevention, maternal-child health","RECRUITING","2026-04-07",{"date":34,"type":35},"2026-04-13","ACTUAL",{"date":37,"type":35},"2024-06-19",{"date":39,"type":22},"2029-03-30",{"name":41,"class":42},"JHSPH Center for Clinical Trials","OTHER",9,{"id":45,"slug":46,"hasResults":11,"nctId":47,"briefTitle":48,"officialTitle":48,"acronym":49,"eligibilityCriteria":50,"healthyVolunteers":11,"sex":51,"minAge":52,"maxAge":4,"enrollmentInfo":53,"targetDuration":4,"studyType":23,"phases":55,"briefSummary":57,"conditions":58,"keywords":60,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":73},"100545061","phase-3-multi-center-clean-air-randomized-controlled-trial-in-copd-100545061","NCT06376994","Multi-Center Clean Air Randomized Controlled Trial in COPD","Clean Air","Inclusion criteria\n\nTo be eligible, subjects must meet all these criteria:\n\n1. Age ≥ 40 years.\n2. Self-report of physician diagnosis of COPD.\n3. Spirometry confirmed airway obstruction (post-bronchodilator spirometry of forced expiratory volume in 1 second (FEV1)\u002Fforced vital capacity (FVC) \\\u003C 0.7) as defined by the Global Initiative for Obstructive Lung Disease (GOLD) criteria (6, 11)\n4. Tobacco exposure ≥ 10 pack-years. This refers to regular cigarette tobacco consumption.\n5. Self-reported former smoker of at least 6 months' duration. This does not include e-cigarette use.\n6. COPD Assessment Test (CAT) score ≥ 10, Modified Medical Research Council dyspnea scale (mMRC) ≥ 2, or history of moderate or severe exacerbation in the past 12 months (as defined by history of receiving a course of systemic corticosteroids or antibiotics for respiratory problems; or visiting an emergency department or being hospitalized for a COPD exacerbation within the past 12 months.)\n\nExclusion criteria\n\nTo be eligible, subjects must not meet any one of these criteria:\n\n1. Living in a location other than home (e.g., long-term care facility, nursing home)\n2. Other chronic lung diseases, except asthma\n3. Condition with less than a year of life expectancy (e.g., metastatic cancer) or in hospice\n4. Spends \\>2 months per year in location other than home; or plans to change residence in the next 12 months\n5. Pregnant or breastfeeding\n6. Current air cleaner use in the home (\\*If the individual is willing to discontinue use of the personal air cleaner, this person can be eligible if all other eligibility has been met)\n7. Inability to bring air cleaners (about 15 pounds each) into home, either by self, friend, or relative\n8. Deemed by the study investigator to be unable to complete study protocol, including likely lack of internet connectivity\n9. Participating in another interventional clinical trial","ALL","40 Years",{"count":54,"type":22},770,[56],"PHASE3","This is a multi-center randomized, sham-controlled clinical trial to determine the effectiveness of an air cleaner intervention aimed at improving indoor air quality on reducing COPD exacerbation risk and improving quality of life, functional status, rescue medication use.",[59],"Chronic Obstructive Pulmonary Disease (COPD)",[61,62,63,64],"air cleaner","indoor air quality","quality of life","rescue medication use","2025-10-08",{"date":67,"type":35},"2025-10-10",{"date":69,"type":35},"2024-05-24",{"date":71,"type":22},"2029-11-30",{"name":41,"class":42},11,""]