[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Jakub Szrama\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":72},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,46],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":45},"100535096","the-hypotension-prediction-index-in-major-abdominal-surgery-100535096",false,"NCT06247384","The Hypotension Prediction Index in Major Abdominal Surgery","The Hypotension Prediction Index in Major Abdominal Surgery - a Prospective Randomized Clinical Trial.","Inclusion Criteria:\n\n* Patients qualified for elective major abdominal surgery, defined as an expected duration of more than two hours, an estimated blood loss of \\>15% of blood volume, or an expected transfusion requirement of at least two packed red blood cells with general or combined anaesthesia.\n* Patients with American Society of Anesthesiologists (ASA) status III or IV.\n* Written informed consent.\n\nExclusion Criteria:\n\n* Patients under 18 years\n* Lack of health insurance\n* Pregnancy\n* Known history of congenital heart disease, severe aortic and\u002For mitral stenosis, heart failure and ejection fraction \\\u003C 35 %\n* Persistent atrial fibrillation and other arrhythmias impairing arterial pressure cardiac output monitoring","ALL","18 Years","80 Years",{"count":20,"type":21},226,"ESTIMATED","INTERVENTIONAL",[24],"NA","The goal of this randomized clinical trial is to compare different types of advanced hemodynamic monitoring in patients undergoing major abdominal surgery.\n\nParticipants undergoing major abdominal surgery will receive anesthesia with two different types of hemodynamic monitoring - group A will receive arterial pressure cardiac output algorithm with the FloTrac sensor and group B will receive hemodynamic monitoring with the Hypotension Prediction Index.\n\nThe main question the study aims to answer is:\n\n• will the hypotension prediction index algorithm reduce the rate of hypotension in comparison to arterial pressure cardiac output algorithm.",[27],"Hypotension During Surgery",[29,30,31,32],"hypotension prediction index","major abdominal surgery","arterial pressure cardiac output","intraoperative hypotension","RECRUITING","2025-07-30",{"date":36,"type":37},"2025-08-03","ACTUAL",{"date":39,"type":37},"2025-01-01",{"date":41,"type":21},"2025-12-31",{"name":43,"class":44},"Jakub Szrama","OTHER",1,{"id":47,"slug":48,"hasResults":11,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":4,"eligibilityCriteria":52,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":53,"targetDuration":4,"studyType":22,"phases":55,"briefSummary":56,"conditions":57,"keywords":62,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":66,"startDateStruct":67,"completionDateStruct":69,"leadSponsor":71,"locationsCount":45},"100496007","the-hypotension-prediction-index-in-free-flap-transplant-in-head-and-neck-surgery-100496007","NCT05738603","The Hypotension Prediction Index in Free Flap Transplant in Head and Neck Surgery.","The Hypotension Prediction Index in Free Flap Transplant in Head and Neck Surgery - a Prospective Randomized Controlled Trial.","Inclusion Criteria:\n\n* Patients qualified to head and neck free flap surgery\n* Written informed consent\n\nExclusion Criteria:\n\n* Patients under 18 years\n* Lack of health insurance\n* Pregnancy\n* Known history of congenital heart disease, severe aortic and\u002For mitral stenosis, heart failure and ejection fraction \\\u003C 35 %\n* Persistent atrial fibrillation and other arrhythmias impairing arterial pressure-based cardiac output (APCO) monitoring",{"count":54,"type":21},206,[24],"The aim of the current study is to evaluate the effects of the Hypotension Prediction Index (HPI) on the degree of intraoperative hypotension in patients undergoing free flap surgery. The hypothesis is that implementation of the HPI algorithm will reduce the time-weighted average (TWA) intraoperative hypotension below a threshold of 65 mmHg (16), and to reveal the relationship between the episodes of hypotension and free flap viability and function.",[58,59,60,61],"Hypotension","Head and Neck Cancer","Perioperative Complication","Postoperative Complications",[58,63,64,59,65],"Hypotension Prediction Index","Free Flap Transplant","Perioperative Complications",{"date":36,"type":37},{"date":68,"type":37},"2024-09-01",{"date":70,"type":21},"2026-12",{"name":43,"class":44},""]