[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Jason Wilken\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":74},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,47],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100543201","from-opinion-to-evidence-multi-site-evaluation-of-custom-dynamic-orthosis-best-practices-100543201",false,"NCT06352788","From Opinion to Evidence: Multi-site Evaluation of Custom Dynamic Orthosis Best Practices","AFOSVA","Inclusion Criteria:\n\n* Between the ages of 18 and 65\n* 2 or more years from a traumatic injury below the knee\n* Ability to be fit with an orthosis\n* Any of the following:\n\n  * Weakness of ankle plantarflexors (\\\u003C4\u002F5 on manual muscle test)\n  * Limited pain-free ankle motion (dorsiflexion (DF) \\\u003C10° or plantarflexion (PF) \\\u003C20°)\n  * Mechanical pain with loading to hindfoot\u002Fmidfoot (\\>=4\u002F10 Numerical pain rating scale)\n  * Fusion or candidate for fusion of the ankle or hindfoot\n  * Candidate for amputation secondary to ankle\u002Ffoot injury and impairment\n\nExclusion Criteria:\n\n* Pain greater than 8\u002F10 at rest\n* Ankle weakness or spasticity as a result of spinal cord injury or central nervous system pathology\n* Use of an orthosis including the knee\n* Non-ambulatory\n* Surgery on study limb anticipated in next 4 months\n* Medical or psychological conditions that would influence functional testing (e.g., severe traumatic brain injury, stroke, heart disease, vestibular disorder)\n* Neurologic, musculoskeletal, or other conditions limiting function of the contralateral extremity\n* Uncorrected visual or hearing impairments\n* Pregnancy\n* Non-English speaking\n* BMI \\> 40","ALL","18 Years","65 Years",{"count":20,"type":21},35,"ESTIMATED","INTERVENTIONAL",[24],"NA","This study is designed to support evidence-based practice and optimal care by evaluating how different configurations of two types of carbon fiber custom dynamic orthoses (CDOs) influences outcomes following traumatic lower extremity injury.",[27],"Foot Injury",[29,30,31,32,33],"Ankle Foot Orthosis","Carbon Fiber","Gait","Biomechanics","Physical Performance","RECRUITING","2026-01-13",{"date":37,"type":38},"2026-01-15","ACTUAL",{"date":40,"type":38},"2024-07-02",{"date":42,"type":21},"2028-09-01",{"name":44,"class":45},"Jason Wilken","OTHER",5,{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":51,"acronym":52,"eligibilityCriteria":53,"healthyVolunteers":54,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":55,"targetDuration":4,"studyType":22,"phases":57,"briefSummary":58,"conditions":59,"keywords":61,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":73},"100616931","the-effects-of-footplate-stiffness-on-foot-loading-within-carbon-fiber-custom-dynamic-orthoses-100616931","NCT07312032","The Effects of Footplate Stiffness on Foot Loading Within Carbon Fiber Custom Dynamic Orthoses","CDOCFPlate","Inclusion Criteria\n\n* Between the ages of 18 and 65\n* Healthy without current complaint of lower extremity pain, spine pain, open wounds or active infections, or medical or neuromusculoskeletal disorders that have limited their participation in work or exercise in the last 6 months\n* Able to hop without pain\n* Able to perform a full squat without pain\n* Ability to read and write in English and provide written informed consent\n* Ability to fit in a generic sized CDO\n\nExclusion Criteria\n\n* Diagnosed with a moderate or severe brain injury\n* Lower extremity injury resulting in surgery or limiting function for greater than 6 weeks\n* Injuries that would limit performance in this study\n* Diagnosed with a physical or psychological condition that would preclude functional testing (e.g. cardiac condition, clotting disorder, pulmonary condition)\n* Visual or hearing impairments that limit walking ability or limit the ability to comply with instructions given during testing\n* Require use of an assistive device\n* Unhealed wounds (cuts\u002Fabrasions) that would prevent AFO use\n* BMI \\> 40\n* Pregnancy",true,{"count":56,"type":21},20,[24],"Carbon fiber custom dynamic orthoses (CDOs) improve function, reduce pain, and offload the foot and ankle. CDOs include a proximal cuff that wraps around the leg just below the knee, a posterior carbon fiber strut that bends to store and return energy, and a semi-rigid carbon fiber footplate. The purpose of this study is to determine the effect of CDO use and CDO footplate stiffness on foot loading, limb mechanics, pain, and comfort.",[60],"Trauma Injury",[62,63,64],"carbon fiber","traumatic injury","ankle foot orthosis","2025-12-29",{"date":67,"type":38},"2025-12-31",{"date":69,"type":38},"2025-12-13",{"date":71,"type":21},"2027-12-01",{"name":44,"class":45},1,""]