[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Jeju National University Hospital\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":46},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":22,"studyType":23,"phases":4,"briefSummary":24,"conditions":25,"keywords":28,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":5},"100631222","long-term-prospective-study-of-korean-cadasil-patients-100631222",false,"NCT07497867","Long-term Prospective Study of Korean CADASIL Patients","Long-term Prognosis of Korean Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy(CADASIL) Patients: A Multicenter Prospective Study","K-CADASIL","Inclusion Criteria:\n\n* Age ≥ 19 years\n* CADASIL suspected or confirmed by genetic testing (NOTCH3 mutation)\n* Able to provide written informed consent (participant or legally authorized representative)\n\nExclusion Criteria:\n\n* Contraindication to MRI (claustrophobia, metal implants, pacemaker)\n* Acute ischemic or hemorrhagic stroke within 180 days prior to enrollment","ALL","19 Years",{"count":20,"type":21},500,"ESTIMATED","10 Years","OBSERVATIONAL","K-CADASIL is a 10-year prospective study of 500 Korean patients with cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL), a genetic brain disease that causes stroke and dementia. The investigators will track symptoms, brain scans, memory tests, and gene information to understand disease progression in Koreans and identify better treatments. Participants will visit clinics regularly for check-ups and blood tests. This study aims to help improve care for CADASIL patients and families worldwide.",[26,27],"CADASIL","Cerebral Autosomal Dominant Arteriopatie With Subcortical Infarcts and Leukoencephalopathy",[26,29,30,31,32,33],"NOTCH3","Stroke","Cerebral Small Vessel Disease","Prospective Study","Korea","RECRUITING","2026-05-11",{"date":37,"type":38},"2026-05-14","ACTUAL",{"date":40,"type":38},"2023-07-10",{"date":42,"type":21},"2040-12-31",{"name":44,"class":45},"Jeju National University Hospital","OTHER",""]