[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Jinwei Tian\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":74},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,45],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":20,"enrollmentInfo":21,"targetDuration":24,"studyType":25,"phases":4,"briefSummary":26,"conditions":27,"keywords":30,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":44},"100604566","diagnosis-prognosis-and-mechanisms-in-panvascular-disease-100604566",false,"NCT07151183","Diagnosis, Prognosis, and Mechanisms in Panvascular Disease","A Prospective Research on Diagnosis, Prognosis, and Mechanisms of Panvascular Disease","PRO-PVD","Inclusion Criteria:\n\n1. Male or female aged 18 to 80 years old;\n2. Diagnosed or suspected panvascular disease, defined as the presence of atherosclerotic lesions in at least two or more vascular regions, such as intracranial arteries, carotid arteries, coronary arteries, aorta, and peripheral arteries;\n3. Voluntary participation in this study and provision of signed informed consent.\n\nExclusion Criteria:\n\n1. Severe hemodynamic instability;\n2. Severe cardiac dysfunction (EF \\\u003C 30%);\n3. Severe arrhythmias;\n4. Severe valvular heart disease;\n5. Cardiomyopathy caused by non-coronary artery diseases;\n6. Non-atherosclerotic coronary artery disease (e.g., coronary artery dissection, embolism, etc.);\n7. Severe non-cardiovascular diseases;\n8. Women who are pregnant or breastfeeding;\n9. Individuals who refuse to provide signed informed consent.",true,"ALL","18 Years","80 Years",{"count":22,"type":23},1000,"ESTIMATED","1 Year","OBSERVATIONAL","This study aims to establish a standardized cohort for panvascular diseases, encompassing biological materials such as DNA samples, along with extensive patient medical records and follow-up information. The design of this database will enable it to serve as a comprehensive resource for future medical research.\n\nUpon data collection, researchers will conduct various statistical analyses to enhance our understanding of the factors and mechanisms contributing to various panvascular diseases, including coronary heart disease, myocardial infarction, stroke, and peripheral vascular disease. These statistical analyses will also aid in identifying more effective treatment strategies for these conditions.\n\nBy amassing a large volume of data from a significant number of patients with panvascular diseases, researchers will be able to perform highly precise analyses of the factors influencing the onset, progression, and treatment of these diseases. The results of these precise analyses can then be utilized to optimize clinical practices for the prevention and treatment of panvascular diseases.",[28,29],"Panvascular Diseases","Cardiovascular Diseases",[31,29],"Panvascular disease","RECRUITING","2025-09-02",{"date":35,"type":36},"2025-09-03","ACTUAL",{"date":38,"type":36},"2024-12-01",{"date":40,"type":23},"2030-12-31",{"name":42,"class":43},"Jinwei Tian","OTHER",1,{"id":46,"slug":47,"hasResults":11,"nctId":48,"briefTitle":49,"officialTitle":49,"acronym":4,"eligibilityCriteria":50,"healthyVolunteers":17,"sex":18,"minAge":51,"maxAge":52,"enrollmentInfo":53,"targetDuration":4,"studyType":25,"phases":4,"briefSummary":55,"conditions":56,"keywords":60,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":44},"100602548","chinese-migrant-population-health-cohort-100602548","NCT07124949","Chinese Migrant Population Health Cohort","Inclusion Criteria:\n\n1. Permanent residents of Harbin or Hainan who will continue to reside in Harbin or Hainan for the next 5 years.\n2. Baseline age ≥60 years, with basic communication and comprehension abilities.\n3. No confirmed diagnosis of end-stage major organic diseases (e.g., advanced heart failure, advanced liver failure, advanced kidney failure, malignant tumors).\n4. Able to perform activities of daily living independently and capable of completing questionnaires and physical examinations.\n5. Willing to participate in the study, provide written informed consent, accept long-term follow-up, and provide biological specimens.\n\nExclusion Criteria:\n\n1. Occurrence of life-threatening acute events (e.g., myocardial infarction, acute heart failure, stroke) within the past 30 days.\n2. Currently receiving chronic treatment with antiviral drugs (e.g., for HIV) or antipsychotic medications.\n3. Presence of moderate to severe cognitive impairment preventing survey completion or follow-up cooperation.\n4. Current acute infectious diseases such as influenza or fever.\n5. Simultaneous participation in other interventional clinical studies.\n6. Refusal to sign informed consent or unwillingness to provide biological specimens.\n7. Any other condition deemed unsuitable for study participation by the investigators based on overall assessment.","60 Years","120 Years",{"count":54,"type":23},26000,"The Chinese Migrant Population Health Cohort is a prospective, multi-center study jointly initiated by Professor Yong Ji, President of Harbin Medical University, and Academician Guoqiang Chen, President of Hainan Medical University, in collaboration with regional partners. It targets older adults (≥60 years) who engage in seasonal migration between cold (Heilongjiang) and tropical (Hainan) regions. The primary objective is to investigate cardiovascular and metabolic disease risks, underlying biological and environmental mechanisms, and effective preventive strategies in this unique population.\n\nParticipants are recruited from both origin and destination sites and undergo standardized baseline assessments, including questionnaires, physical examinations, medical imaging, biospecimen collection (blood, stool, hair, nails), and environmental exposure monitoring. Longitudinal follow-up includes periodic reassessments, remote monitoring, and data linkage with hospital information systems to capture health outcomes.\n\nThe study aims to:\n\nDefine migration-related health risk profiles and disease phenotypes.\n\nElucidate biological and environmental mechanisms influencing disease onset and progression.\n\nDevelop AI-driven risk prediction models and evaluate targeted interventions through nested randomized controlled trials.\n\nTranslate findings into clinical guidelines and scalable cross-regional health management models.\n\nThis is the first cohort in China to systematically investigate the health impacts of seasonal migration in older adults. By integrating epidemiology, multi-omics, environmental data, and health policy translation, the study seeks to improve continuity of care, strengthen climate adaptation, and promote healthy ageing.",[29,57,58,59],"Metabolic Disorders","Ageing and Geriatric Health","Climate Adaptation",[29,61,62,63,64,65],"Metabolic Diseases","Geriatrics","Migration","Climate Change","Health Promotion","2025-08-14",{"date":68,"type":36},"2025-08-20",{"date":70,"type":36},"2025-07-23",{"date":72,"type":23},"2030-04-30",{"name":42,"class":43},""]