[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Jonathon Myers\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":45},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":30,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":5},"100610487","phase-4-standalone-istent-infinite-and-idose-tr-for-management-of-moderate-to-severe-open-angle-glaucoma-100610487",false,"NCT07228221","Standalone iStent Infinite and iDose TR for Management of Moderate to Severe Open Angle Glaucoma","iStent Infinite and iDose TR for Management of Moderate to Severe Primary Open Angle Glaucoma Are a Safe and Effective Alternative to Filtering Surgery for IOP Reduction in Patients With Medically Uncontrolled Glaucoma. (POAG)","POAG","Inclusion Criteria:\n\n* Moderate to severe open angle glaucoma (including POAG, PG, and PXG)\n* Open angle configuration (Shaffer grade ≥ 3), normal angle anatomy9\n* Visual acuity HM or better\n* VF MD -6dB or worse\n* Failed medical therapy and\u002For laser treatment\n* Incisional glaucoma surgery contemplated as next intervention\n* Phakic or pseudophakic\n\nExclusion Criteria:\n\n* Traumatic, uveitic, neovascular glaucoma, or angle closure glaucoma\n* Previous incisional glaucoma surgery\n* ALT; History of iridotomy, SLT, or micropulse laser trabeculoplasty within the prior 90 days\n* Active ocular inflammation or edema, clinically significant corneal dystrophy\n* Corneal or other pathology preventing accurate Goldmann applanation tonometry","ALL","18 Years",{"count":20,"type":21},20,"ESTIMATED","INTERVENTIONAL",[24],"PHASE4","The Investigators will investigate the efficacy of combining the standalone iStent infinite and iDose that are minimally invasive surgical and drug depot options are a safe and effective alternative to filtering surgery for intraocuar pressure reduction in patients with medically uncontrolled open angle glaucoma.",[27,28,29],"Open Angle Glaucoma","Pigmentary Glaucoma","Pseudoexfoliation Glaucoma",[15,31,32],"PG","PXG","RECRUITING","2025-11-13",{"date":36,"type":37},"2025-11-14","ACTUAL",{"date":39,"type":21},"2026-01-05",{"date":41,"type":21},"2031-12-31",{"name":43,"class":44},"Jonathon Myers","OTHER",""]