[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Jordan University of Science and Technology\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":129},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,51,75,105],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":29,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":39,"lastUpdatePostDateStruct":40,"startDateStruct":43,"completionDateStruct":45,"leadSponsor":47,"locationsCount":50},"100557033","the-effect-of-therapeutic-exercise-on-cartilage-morphology-and-physical-function-for-individuals-at-high-risk-of-knee-osteoarthritis-100557033",false,"NCT06532851","The Effect of Therapeutic Exercise on Cartilage Morphology and Physical Function for Individuals at High Risk of Knee Osteoarthritis","The Efficacy of Progressive Resistance Exercises Versus Aerobic Exercises on Cartilage Morphology and Physical Function in Patients With Degenerative Meniscus Tear: A Randomized Controlled Trial","Inclusion Criteria:\n\n1. Are between 35 and 55 years of age.\n2. Have a symptomatic degenerative medial meniscus tear as evidenced by:\n\n   * Presence of medial knee pain.\n   * Medial joint line tenderness.\n   * Pain and limited motion when attempting to perform a full squat and\n   * Increased intra-meniscal signal on at least 2 consecutive MRI slices and\n3. Have clearance from their personal physician to participate in an exercise program.\n\nExclusion Criteria:\n\n1. Radiographic evidence of OA (K-L grade 2 or above).\n2. A repairable meniscus injury (longitudinal tear in the outer 1\u002F3 of the meniscus).\n3. A meniscus injury that requires meniscectomy (locked knee).\n4. Prior or current ligament injury or surgery of the involved knee.\n5. Prior or current injury or surgery to contra-lateral knee.\n6. Pathological ligamentous laxity upon examination of the knee\n7. An inflammatory arthritic condition or\n8. Any injury or condition involving the lower extremities that affects their ability to walk.\n\nBecause participation in this study requires undergoing MRI, subjects will be excluded if they:\n\n1. If female, pregnant at the time of enrollment.\n2. Had prior surgery for an aneurysm; any medical illness that may interfere with the patient's general fitness or exercise capability.\n3. Had any contraindication with MRI.\n4. Had surgery within the past two months.\n5. Have a cardiac pacemaker.",true,"ALL","35 Years","55 Years",{"count":21,"type":22},50,"ESTIMATED","INTERVENTIONAL",[25],"NA","This randomized controlled trial aims to evaluate the efficacy of progressive resistance exercises (PRE) versus aerobic exercises on cartilage morphology and physical function in patients with degenerative meniscus tears. 45 participants, aged 35-55, will be randomly assigned to one of three groups: PRE, aerobic exercise, or control (standard of care physical and medical therapy). The study will utilize MRI T2 mapping to assess changes in cartilage composition and patient-reported and performance-based measures to evaluate clinical outcomes. This pilot study will also determine the feasibility and issues related to recruitment and retention for a larger trial.",[28],"Meniscus Tear",[30,31,32,33,34,35,36,37],"Degenerative Meniscus Tear","MRI T2 Mapping","Progressive Resistance Exercise","Aerobic Exercise","Knee Pain","Cartilage Morphology","Exercise Therapy","Early Knee Osteoarthritis","RECRUITING","2026-05-07",{"date":41,"type":42},"2026-05-12","ACTUAL",{"date":44,"type":42},"2023-06-01",{"date":46,"type":22},"2031-03-01",{"name":48,"class":49},"Jordan University of Science and Technology","OTHER",2,{"id":52,"slug":53,"hasResults":11,"nctId":54,"briefTitle":55,"officialTitle":55,"acronym":4,"eligibilityCriteria":56,"healthyVolunteers":16,"sex":17,"minAge":57,"maxAge":18,"enrollmentInfo":58,"targetDuration":4,"studyType":23,"phases":60,"briefSummary":61,"conditions":62,"keywords":64,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":74},"100617413","effect-of-injectable-hyaluronic-acid-hyadent-bg-ha-on-bone-healing-in-extraction-sockets-100617413","NCT07318298","Effect of Injectable Hyaluronic Acid (HYADENT BG (HA)) on Bone Healing in Extraction Sockets","Inclusion Criteria:\n\nMale and female participants aged 18 to 35 years\n\nPresence of bilateral impacted mandibular third molars classified as Pell and Gregory Class II, Position B\n\nClassified as American Society of Anesthesiologists (ASA) Physical Status I\n\nAbsence of active local infection at the surgical site (e.g., no swelling, trismus, hyperthermia)\n\nAbility to maintain adequate oral hygiene\n\nAbility to understand and provide written informed consent\n\nAbility to read and understand Arabic or English\n\nWillingness to comply with study procedures and follow-up visits\n\nExclusion Criteria:\n\nHistory of systemic diseases such as diabetes mellitus, hypertension, gastric ulcer, or other significant medical conditions\n\nPresence of severe or chronic illness requiring frequent hospitalization\n\nPregnant or breastfeeding individuals\n\nHistory of cognitive or motor impairment that may interfere with study participation\n\nUse of anti-inflammatory or analgesic medications within two weeks before surgery\n\nKnown allergy or hypersensitivity to nonsteroidal anti-inflammatory drugs (NSAIDs)\n\nCurrent smoker\n\nUse of anticoagulant therapy\n\nAny condition that, in the investigator's judgment, may interfere with healing or study outcomes","18 Years",{"count":59,"type":22},20,[25],"Complications such as postoperative pain and delayed socket healing are relatively common following surgical extraction of mandibular third molars. Various biomaterials have been investigated to enhance wound healing and reduce postoperative morbidity. Hyaluronic acid (HA) has demonstrated anti-inflammatory and regenerative properties that may improve both soft and hard tissue healing.\n\nThe aim of this study is to evaluate the effect of topical hyaluronic acid on postoperative pain and alveolar socket bone healing following surgical extraction of mandibular third molars. A prospective, randomized, controlled clinical trial with a split-mouth design will be conducted. Twenty patients requiring bilateral mandibular third molar surgical extraction will be enrolled. In each patient, one extraction socket will receive hyaluronic acid combined with a collagen sponge, while the contralateral socket will receive a collagen sponge alone, according to random allocation. Postoperative pain will be assessed using a visual analogue scale, and socket healing will be evaluated radiographically and histologically.",[63],"The Application of Hyaluronic Acid on Teeth Bone Healing. Hyaluronic Acid Which is Widely Used in Medicine for Joint, Eye Care, Wound Healing",[65],"hyauronic acid, wisdom teeth extraction, bone healing","2026-01-27",{"date":68,"type":42},"2026-01-28",{"date":70,"type":42},"2024-08-01",{"date":72,"type":22},"2026-04-30",{"name":48,"class":49},1,{"id":76,"slug":77,"hasResults":11,"nctId":78,"briefTitle":79,"officialTitle":80,"acronym":4,"eligibilityCriteria":81,"healthyVolunteers":11,"sex":17,"minAge":57,"maxAge":4,"enrollmentInfo":82,"targetDuration":4,"studyType":23,"phases":84,"briefSummary":85,"conditions":86,"keywords":88,"overallStatus":96,"whyStopped":4,"lastUpdateSubmitDate":97,"lastUpdatePostDateStruct":98,"startDateStruct":100,"completionDateStruct":102,"leadSponsor":104,"locationsCount":74},"100564127","pmr-vs-mm-for-patients-on-hemodialysis-100564127","NCT06625125","PMR vs MM for Patients on Hemodialysis","The Differential Effects of Mindfulness-Based Intervention and Progressive Muscle Relaxation on Expression Suppression, Cognitive Reappraisal, and Perceived Stress in Patients With End-Stage Renal Disease: A Randomized Trial","Inclusion Criteria:\n\n* patients with ESRD undergoing hemodialysis at least three sessions a week\n* being at least 18 years old\n* having a smartphone\n* being capable of reading and writing in Arabic\n\nExclusion Criteria:\n\n* Patients under psychotherapy or taking regular psychopharmacological and analgesic treatment",{"count":83,"type":22},159,[25],"Background: Hemodialysis is considered as an effective therapy to remove harmful waste from the body and to improve the quality of life in patients suffering from end-stage renal disease (ESRD). However, patients who receive hemodialysis perceive various stressors that are harmful to their physical and psychological well-being. Therefore, it is necessary to implement effective and practical therapeutic strategies to enhance the quality of life in this population. Mindfulness-based intervention (MBI) and progressive muscle relaxation (PMR) are effective mind-body connection programs that are inadequately used in patients undergoing hemodialysis.\n\nObjectives: This study will examine the differential effects of mindfulness-based intervention (MBI) and progressive muscle relaxation (PMR) on expression suppression, cognitive reappraisal, and perceived Stress in Patients with End-Stage Renal Disease undergoing hemodialysis in Jordan.\n\nMethods: An experimental parallel control, randomized design will be implemented among 159 PwESRD undergoing hemodialysis in a big referral Hospital in Jordan. Simple random assignation will be used to create three equal groups including PMR, MBI, and control groups (N= each). Both groups will practice their assigned intervention over five weeks (with three half-hour sessions per week) during hemodialysis sessions. The study variables will be measured for the three groups at the outset and eight weeks after initiation. Variables will be measured by the self-reporting questionnaire including sociodemographic characteristic sheet, the Mindfulness attention awareness scale (MAAS) the Perceived Stress Scale (PSS), and the Emotion Regulation Questionnaire (ERQ). Repeated measures analysis of variance (RM ANOVA) will be used to analyze the main study data.",[87],"End Stage Renal Disease",[89,90,91,92,93,94,95],"Hemodialysis","End stage renal disease","Mindfulness meditation","Progressive muscle relaxation","Cognitive reappraisal","Behavioral suppression","Perceived stress","NOT_YET_RECRUITING","2024-10-01",{"date":99,"type":42},"2024-10-03",{"date":101,"type":22},"2024-10",{"date":103,"type":22},"2025-01",{"name":48,"class":49},{"id":106,"slug":107,"hasResults":11,"nctId":108,"briefTitle":109,"officialTitle":110,"acronym":4,"eligibilityCriteria":111,"healthyVolunteers":11,"sex":17,"minAge":57,"maxAge":4,"enrollmentInfo":112,"targetDuration":4,"studyType":23,"phases":114,"briefSummary":115,"conditions":116,"keywords":118,"overallStatus":96,"whyStopped":4,"lastUpdateSubmitDate":122,"lastUpdatePostDateStruct":123,"startDateStruct":125,"completionDateStruct":126,"leadSponsor":128,"locationsCount":74},"100563902","the-effect-of-mindfulness-on-emotional-regulations-skills-and-quality-of-life-among-patients-on-hemodialysis-100563902","NCT06622200","The Effect of Mindfulness on Emotional Regulations Skills and Quality of Life Among Patients on Hemodialysis","The Effects of Mindfulness-based Intervention on Trait Mindfulness, Cognitive Reappraisal, Behavioral Suppression, and Quality of Life Among Patients Undergoing Hemodialysis.","Inclusion Criteria:\n\n* Patients with ESRD undergoing hemodialysis at least three sessions a week\n* Being at least 18 years old\n* Having a smartphone\n* Being capable of reading and writing in Arabic\n\nExclusion Criteria:\n\n* Patients under psychotherapy or taking regular psychopharmacological and analgesic treatment",{"count":113,"type":22},120,[25],"The study aims to investigate how mindfulness-based intervention (MBI) impacts trait mindfulness, cognitive reappraisal, expressive suppression and quality of life in patients with end-stage renal disease (ESRD) undergoing hemodialysis.\n\nA Randomized controlled trial will be conducted with patients diagnosed with ESRD and undergoing hemodialysis treatment. Participants selected using a convenience sampling method will be randomly assigned into the intervention group (n=52) who received MBI, and the control group (n=52) who received a similar intervention after the study. The intervention involves a 30-minute MBI introduced three sessions per week during hemodialysis sessions over five weeks. Outcome measures included the Mindful Attention Awareness Scale (MAAS) to assess trait mindfulness, the Emotion Regulation Questionnaire (ERQ) for cognitive reappraisal and behavioral suppression, and the Kidney Disease-related Quality of Life Questionnaire for quality of life. Data were collected at baseline and post-intervention.",[117],"End-Stage Kidney Disease",[119,93,94,120,121],"hemodialysis","mindfulness","quality of life","2024-09-29",{"date":124,"type":42},"2024-10-02",{"date":101,"type":22},{"date":127,"type":22},"2024-11",{"name":48,"class":49},""]