[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Jose Ivan Rodriguez de Molina Serrano\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":78},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,47],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":4},"100593311","prognostic-value-of-transcranial-doppler-ultrasound-in-the-clinical-evolution-of-patients-with-acute-ischemic-stroke-the-trade-ais-study-100593311",false,"NCT07004790","Prognostic Value of Transcranial Doppler Ultrasound in the Clinical Evolution of Patients With Acute Ischemic Stroke. The TRADE-AIS Study","Prognostic Value of Transcranial Doppler Ultrasound in the Clinical Evolution of Patients With Acute Ischemic Stroke: A Prospective Observational Study","TRADE-AIS","Inclusion Criteria:\n\n* Age ≥ 18 years\n* Clinical diagnosis of acute ischemic stroke\n* Onset of symptoms ≤ 24 hours before admission\n* Underwent or will undergo transcranial Doppler ultrasound within 24 hours of symptom onset\n* Able to provide informed consent or consent obtained from a legal representative\n\nExclusion Criteria:\n\n* Evidence of intracerebral hemorrhage on imaging\n* Inadequate temporal acoustic window for transcranial Doppler\n* Intubated or hemodynamically unstable prior to Doppler evaluation\n* Known diagnosis of neurodegenerative disease significantly affecting baseline neurological function (e.g., advanced dementia, Parkinson's disease)\n* Refusal to participate or withdrawal of consent","ALL","18 Years",{"count":20,"type":21},50,"ESTIMATED","INTERVENTIONAL",[24],"NA","This prospective observational study aims to determine whether specific parameters measured by transcranial Doppler ultrasound (TCD) can predict clinical outcomes in patients with acute ischemic stroke (AIS). The primary objective is to evaluate the association between middle cerebral artery (MCA) flow velocities and short-term neurological improvement. Secondary outcomes include the presence of collateral flow and flow patterns in relation to functional recovery measured by NIHSS and modified Rankin Scale (mRS) scores.",[27],"Stroke",[29,30,31,32,33,34],"stroke","transcranial doppler","Prognosis","Middle Cerebral Artery","Cerebral Hemodynamics","Mexico","NOT_YET_RECRUITING","2025-09-13",{"date":38,"type":39},"2025-09-16","ACTUAL",{"date":41,"type":21},"2026-08-01",{"date":43,"type":21},"2027-08-30",{"name":45,"class":46},"Jose Ivan Rodriguez de Molina Serrano","OTHER",{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":53,"eligibilityCriteria":54,"healthyVolunteers":11,"sex":17,"minAge":55,"maxAge":4,"enrollmentInfo":56,"targetDuration":58,"studyType":59,"phases":4,"briefSummary":60,"conditions":61,"keywords":65,"overallStatus":70,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":71,"startDateStruct":72,"completionDateStruct":74,"leadSponsor":76,"locationsCount":77},"100593526","risk-factors-for-hospitalization-and-transfusion-criteria-in-patients-with-dengue-virus-infection-100593526","NCT07007585","Risk Factors for Hospitalization and Transfusion Criteria in Patients With Dengue Virus Infection","Risk Factors for Hospitalization and Transfusion Criteria in Patients With Dengue Virus Infection: A Prospective Observational Study","DENGUE-FACT","Inclusion Criteria:\n\n* Patients aged ≥5 years\n* Laboratory-confirmed dengue infection (NS1, IgM, or PCR)\n* First contact at emergency or outpatient services\n* Informed consent signed by the patient or legal guardian\n\nExclusion Criteria:\n\n* Co-infection with other arboviruses or COVID-19\n* Pre-existing hematologic or oncologic disease\n* Refusal to sign informed consent","5 Years",{"count":57,"type":21},100,"1 Month","OBSERVATIONAL","This 3-year prospective observational study aims to identify clinical and laboratory risk factors associated with hospitalization in patients with confirmed dengue virus infection. It also seeks to analyze real-world transfusion practices and their outcomes. The study will be conducted in a second-level hospital in northern Mexico and will follow patients from emergency department entry to clinical resolution or hospital discharge.",[62,63,64],"Dengue","Dengue Fever","Dengue Fever With Warning Signs",[62,66,67,68,69,34],"Hospitalization","Transfusion","Hemorrhagic Fever","Thrombocytopenia","RECRUITING",{"date":38,"type":39},{"date":73,"type":39},"2025-08-01",{"date":75,"type":21},"2028-08-30",{"name":45,"class":46},1,""]