[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Julie Pendergast\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":75},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,40],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":17,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":28,"lastUpdatePostDateStruct":29,"startDateStruct":32,"completionDateStruct":34,"leadSponsor":36,"locationsCount":39},"100505181","feasibility-of-implementing-time-restricted-eating-in-women-with-mild-cognitive-impairment-100505181",false,"NCT05858008","Feasibility of Implementing Time-restricted Eating in Women With Mild Cognitive Impairment","Inclusion Criteria:\n\n* Postmenopausal Women\n* Age 45-95\n* Diagnosis of mild cognitive impairment\n\nExclusion Criteria:\n\n* Individuals prone to hypoglycemia\n* Liver disease\n* Taking medications that affect eating behaviors\n* Alcohol consumption of \\>2 drinks per day\n* Significant circadian disruption\n* Having care-taking responsibilities that significantly affect sleep\n* Shift work or irregular lifestyle\n* Diagnosed clinical eating disorder\n* Participating in a formal weight loss program","FEMALE","45 Years","95 Years",{"count":19,"type":20},15,"ESTIMATED","INTERVENTIONAL",[23],"NA","This study will investigate the feasibility of implementing a time-restricted eating intervention in females with mild cognitive impairment. Targeted therapeutic interventions that improve cognitive impairment and delay onset of ADRD are particularly important for females, who have twice the lifetime risk of developing AD, compared to males.",[26],"Mild Cognitive Impairment","RECRUITING","2025-12-24",{"date":30,"type":31},"2025-12-29","ACTUAL",{"date":33,"type":31},"2024-04-01",{"date":35,"type":20},"2026-06",{"name":37,"class":38},"Julie Pendergast","OTHER",1,{"id":41,"slug":42,"hasResults":11,"nctId":43,"briefTitle":44,"officialTitle":44,"acronym":4,"eligibilityCriteria":45,"healthyVolunteers":46,"sex":15,"minAge":16,"maxAge":47,"enrollmentInfo":48,"targetDuration":4,"studyType":21,"phases":50,"briefSummary":51,"conditions":52,"keywords":55,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":39},"100431064","time-restricted-feeding-intervention-in-metabolically-unhealthy-postmenopausal-women-100431064","NCT04893226","Time-Restricted Feeding Intervention in Metabolically-Unhealthy Postmenopausal Women","Inclusion Criteria:\n\n* postmenopausal women\n* age 45-65 years\n* prediabetic or have at least 2 features of metabolic syndrome\n\nExclusion Criteria:\n\n* on hormone therapy\n* diabetes\n* heart disease\n* alcohol consumption of \\>2 drinks per day\n* significant circadian disruption\n* having care-taking responsibilities that significantly affect sleep\n* shift work or irregular lifestyle\n* uncontrolled sleep apnea or other uncontrolled sleep disorder\n* extreme early or late chronotypes\n* significant psychiatric disorders\n* taking ADHD medications\n* diagnosed dysregulated eating behaviors\n* smoking \\>5 cigarettes\u002Fday or 30 pack-year history\n* participating in formal weight loss program\n* not weight stable",true,"65 Years",{"count":49,"type":20},164,[23],"This is a randomized, parallel two-arm clinical trial design to study the efficacy of time-restricted feeding on metabolic risk in postmenopausal women, who may be particularly vulnerable to disruption of circadian eating rhythms and the associated metabolic dysfunction. It is hypothesized that time-restricted feeding will improve insulin sensitivity, glucose tolerance, body weight, and other metabolic parameters in metabolically-unhealthy postmenopausal women.",[53,54],"Metabolic Syndrome","Postmenopausal Symptoms",[56,57,58,59,60,61,62,63,64,65,66],"postmenopause","weight","metabolic risk","glucose","body composition","lipid","sleep","prediabetes","fasting","circadian","inflammation","2025-11-16",{"date":69,"type":31},"2025-11-19",{"date":71,"type":31},"2021-10-19",{"date":73,"type":20},"2027-01-31",{"name":37,"class":38},""]