[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Kırıkkale University\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":430},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,15,0,[8,49,82,107,129,165,195,227,261,285,316,340,363,389,410],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":23,"studyType":24,"phases":4,"briefSummary":25,"conditions":26,"keywords":30,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":43,"leadSponsor":45,"locationsCount":48},"100617807","effects-of-different-inspiratoryexpiratory-ratios-on-respiratory-and-recovery-outcomes-during-dental-procedures-under-general-anesthesia-in-pediatric-patients-100617807",false,"NCT07323420","Effects of Different Inspiratory:Expiratory Ratios on Respiratory and Recovery Outcomes During Dental Procedures Under General Anesthesia in Pediatric Patients","A Clinical Study on the Effects of Different Inspiratory:Expiratory Ratios on Respiratory Function and Recovery in Pediatric Patients Undergoing Dental Procedures Under General Anesthesia","Inclusion Criteria:\n\n* Pediatric patients scheduled for dental procedures under general anesthesia at our faculty.\n* American Society of Anesthesiologists (ASA) Physical Status I or II.\n* Age between 2 and 12 years.\n* Written informed consent obtained from parents or legal guardians.\n\nExclusion Criteria:\n\n* Patients whose parents or legal guardians decline participation.\n* Presence of adenoid hypertrophy \\>30%.\n* Macroglossia or retrognathia.\n* Severe obesity or developmental delay.\n* History of delayed emergence from anesthesia.\n* ASA Physical Status III or higher.\n* Anesthesia duration less than 1 hour or more than 3 hours.\n* Patients with difficult airway management or ventilation.\n* Known pulmonary or airway diseases or anomalies.\n* Use of pharmacological agents that may affect spontaneous respiratory quality.\n* Presence of neuromuscular disorders affecting respiratory function.\n* Age \\\u003C2 years or \\>12 years.\n* Administration of medications intraoperatively or preoperatively that may influence respiratory dynamics during emergence (e.g., atropine, lidocaine, steroids).",true,"ALL","2 Years","12 Years",{"count":21,"type":22},75,"ESTIMATED","1 Day","OBSERVATIONAL","This observational study aims to evaluate the effects of different inspiratory to expiratory (I:E) ratios (1:2 vs. 1:3) during mechanical ventilation in pediatric patients undergoing dental procedures under general anesthesia. Due to behavioral challenges, dental phobia, or medical conditions, general anesthesia is often required to ensure immobility and cooperation during dental treatments in children.\n\nIn the clinic where the study will be conducted, the I:E ratio is routinely adjusted approximately 20-30 minutes before the end of the procedure to facilitate a smoother transition to spontaneous breathing during emergence from anesthesia. While 1:2 is commonly used, the 1:3 ratio may improve respiratory efficiency and recovery by prolonging the expiratory phase.\n\nThe study aims to compare vital signs, respiratory parameters (heart rate, blood pressure, SpO₂, EtCO₂, respiratory rate), recovery quality, and respiratory complications between the two I:E ratios. The findings aim to optimize ventilation strategies and improve patient comfort and safety during emergence from anesthesia.",[27,28,29],"Respiratory Function","Pediatric Anesthesia","General Anesthesia",[29,31,32,33,34,35],"Anesthesia Recovery","Emergence from Anesthesia","Mechanical Ventilation","I:E Ratio","Recovery Quality","RECRUITING","2026-04-03",{"date":39,"type":40},"2026-04-09","ACTUAL",{"date":42,"type":40},"2026-04-01",{"date":44,"type":22},"2026-11-30",{"name":46,"class":47},"Kırıkkale University","OTHER",1,{"id":50,"slug":51,"hasResults":11,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":4,"eligibilityCriteria":55,"healthyVolunteers":16,"sex":56,"minAge":57,"maxAge":58,"enrollmentInfo":59,"targetDuration":4,"studyType":24,"phases":4,"briefSummary":61,"conditions":62,"keywords":67,"overallStatus":74,"whyStopped":4,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":77,"completionDateStruct":79,"leadSponsor":81,"locationsCount":48},"100631759","biomarkers-in-apical-periodontitis-100631759","NCT07504861","Biomarkers in Apical Periodontitis","Effects of Different Irrigation Activation Techniques on Pro-inflammatory Cytokine and Proteolytic Enzyme Levels in Teeth With Chronic Apical Periodontitis","Inclusion Criteria:\n\n* Male patients aged 18-35 years.\n* Presence of chronic apical periodontitis in maxillary or mandibular incisors, canines, or single-rooted\u002Fsingle-channeled premolars.\n* History of root canal treatment performed at least 4 years ago.\n* Presence of a periapical lesion smaller than 1 cm.\n* Periapical Index (PAI) score of 3 or 4 according to Orstavik classification.\n\nExclusion Criteria:\n\n* Need for antibiotic prophylaxis\n* Diabetes\n* Hematological disorders\n* Use of antibiotics or anti-inflammatory drugs within the last month.\n* Excessive plaque and tartar\n* Gum redness or bleeding\n* Severe gingivitis\n* Widespread periodontitis\n* Periodontal pocket depths exceeding 3 mm.\n* Presence of sinus fistula (bleeding).\n* Presence of internal or external root resorption.\n* Pain on palpation of teeth\n* Swelling\n* Pregnancy during treatment.","MALE","18 Years","35 Years",{"count":60,"type":22},66,"Aim: To evaluate the effects of three different irrigation activation techniques-conventional syringe irrigation (CSI), ultrasonic irrigation (UI), and SWEEPS (Shock Wave Enhanced Emission Photoacoustic Streaming)-on the levels of proinflammatory cytokines (Tumor Necrosis Factor Alpha (TNF-α), interleukin-1beta (IL-1β)) and proteolytic enzymes matrix metalloproteinase-9 (MMP-9) in teeth with chronic apical periodontitis.\n\nMethodology: Sixty-six male patients (aged 18-35) with single-rooted teeth, previous root canal treatment (at least 4 years ago), and periapical lesions (\\\u003C1 cm, PAI score 3 or 4) were included. Sample size was determined by G\\*Power (Power=0.90, α=0.05). Following local anesthesia and rubber dam isolation, endodontic access was performed under a dental operating microscope. After removing old filling material and completing root canal preparation with Reciproc R25\u002FR50 files, patients were randomly assigned into three groups (n=22 each): (1) CSI (30G needle), (2) UI (EMS miniPiezon), and (3) SWEEPS (Er:YAG laser, 2940 nm). Periapical exudate samples were collected using sterile paper points (2 mm beyond the apex for 60s) at the first visit (pre-treatment) and the second visit (one week post-medication with calcium hydroxide). Samples were analyzed via ELISA for TNF-α, IL-1β, and MMP-9 levels.\n\nStatistical Analysis: Data were analyzed using IBM SPSS 20. Percent changes in biomarker levels were evaluated using the Kruskal-Wallis test for inter-group comparisons and the Wilcoxon test for intra-group (pre- vs. post-treatment) comparisons. Linear regression was used to identify effective factors (group, age, gender, tooth type). Significance was set at (p \\\u003C 0.05).\n\nKeywords: Apical periodontitis, SWEEPS, Ultrasonic activation, Cytokines, MMP-9, Endodontics.",[63,64,65,66],"Apical Periodontitis","Retreatment","Biomarkers","Cytokine",[68,69,70,71,72,73],"Apical periodontitis","SWEEPS","Ultrasonic activation","Cytokines","MMP-9","Endodontics","NOT_YET_RECRUITING","2026-03-26",{"date":42,"type":40},{"date":78,"type":22},"2026-03-30",{"date":80,"type":22},"2026-09-28",{"name":46,"class":47},{"id":83,"slug":84,"hasResults":11,"nctId":85,"briefTitle":86,"officialTitle":87,"acronym":4,"eligibilityCriteria":88,"healthyVolunteers":11,"sex":17,"minAge":57,"maxAge":89,"enrollmentInfo":90,"targetDuration":4,"studyType":24,"phases":4,"briefSummary":92,"conditions":93,"keywords":4,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":98,"lastUpdatePostDateStruct":99,"startDateStruct":101,"completionDateStruct":103,"leadSponsor":105,"locationsCount":106},"100549203","osa-risk-level-in-dental-patients-and-correlation-with-complications-after-general-anesthesia-100549203","NCT06430957","OSA Risk Level in Dental Patients and Correlation With Complications After General Anesthesia","Evaluation of OSA Risk Levels in the Preoperative Period of Adult Patients With Planned Dental Procedures Under Anesthesia and Correlation With Postoperative Complications; A Multicenter Study","Inclusion Criteria:\n\n* Patients between 18-80 years of age who apply to the anesthesia clinic for dental procedures planned to be performed under general anesthesia\n* Patients without a previous diagnosis of OSA\n\nExclusion Criteria:\n\n* Individuals who do not want to participate in the study\n* Patients previously diagnosed with OSA\n* Necessity of emergency surgery","80 Years",{"count":91,"type":22},240,"Obstructive sleep apnea (OSA) is a sleep-related respiratory dysfunction. The prevalence of OSA is increasing with the increasing rates of obesity and elderly population worldwide. Perioperative anesthesia management should be adjusted to improve patient safety in patients with OSA. In OSA patients, positive pressure ventilation support may be required in the preoperative period, various ventilation strategies may be required in the intraoperative period, different pharmacologic agents may need to be avoided, and intensive care unit follow-up or noninvasive ventilation support may be required in the postoperative period. However, it is reported that a significant percentage of OSA patients remain undiagnosed. ASA (American Society of Anesthesiologists) has reported the criteria that should be questioned in order to determine the risk of patients in terms of OSA and to initiate the diagnostic process in risky patients and to make appropriate anesthesiologic arrangements in the perioperative period. In addition, the STOP-BANG assessment scale, which is widely used all over the world in OSA risk assessment, is also used in OSA risk assessment. It is thought that dental caries and extraction needs may be higher in OSA patients, especially since open-mouth sleeping accompanies the situation. In this respect, it is also important for patients to be diagnosed with OSA as it may prevent dental damage due to open-mouth sleeping in the future. Identifying patients at risk for OSA and directing them to the diagnostic process is very important for patient safety. Within the scope of the study, the criteria recommended by ASA and STOP-BANG score will be evaluated and recorded. Risk stratification in terms of STOP-BANG questionnaire and ASA criteria will be done separately for each patient and for each classification method. Patients at high risk will be consulted to the relevant medical department in the preoperative period for further investigation and treatment. In addition, it is aimed to correlate the risk levels determined in the study with postoperative respiratory complications and recovery time.",[94,95,96,97],"Obstructive Sleep Apnea Risk Management","Postoperative Complications","Dental Caries Under General Anesthesia","Obstructive Sleep Apnea of Adult","2026-03-19",{"date":100,"type":40},"2026-03-20",{"date":102,"type":40},"2024-06-28",{"date":104,"type":22},"2026-08",{"name":46,"class":47},2,{"id":108,"slug":109,"hasResults":11,"nctId":110,"briefTitle":111,"officialTitle":112,"acronym":4,"eligibilityCriteria":113,"healthyVolunteers":16,"sex":17,"minAge":57,"maxAge":4,"enrollmentInfo":114,"targetDuration":23,"studyType":24,"phases":4,"briefSummary":116,"conditions":117,"keywords":4,"overallStatus":74,"whyStopped":4,"lastUpdateSubmitDate":121,"lastUpdatePostDateStruct":122,"startDateStruct":124,"completionDateStruct":126,"leadSponsor":128,"locationsCount":48},"100627686","chronic-total-occlusion-and-triglyceride-glucose-index-100627686","NCT07451860","Chronic Total Occlusion and Triglyceride-Glucose Index","The Role of the Triglyceride-Glucose Index in Determining the Risk of Chronic Total Occlusion in Coronary Artery Disease","Inclusion Criteria:\n\n* Adults ≥18 years of age, patients undergoing coronary angiography, non-obese individuals\n\nExclusion Criteria:\n\n* Patients \\\u003C18 years of age, history of atrial fibrillation, pacemaker implantation, asthma, pulmonary hypertension, pregnancy, anemia, malignancy, rheumatoid arthritis, or peripheral artery disease, obesity (BMI \\>30 kg\u002Fm²), inaccessible patient records",{"count":115,"type":22},200,"We retrospectively analyzed 200 CAD patients undergoing coronary angiography between 2026-2027. Patients were grouped by CTO presence. Clinical and laboratory parameters were compared, and logistic regression was performed to identify independent predictors.",[118,119,120],"CAD - Coronary Artery Disease","Chronic Total Occlusion (CTO)","Triglycerid Glucose Index","2026-02-28",{"date":123,"type":40},"2026-03-05",{"date":125,"type":22},"2026-03-15",{"date":127,"type":22},"2026-09-15",{"name":46,"class":47},{"id":130,"slug":131,"hasResults":11,"nctId":132,"briefTitle":133,"officialTitle":134,"acronym":135,"eligibilityCriteria":136,"healthyVolunteers":16,"sex":56,"minAge":137,"maxAge":138,"enrollmentInfo":139,"targetDuration":141,"studyType":24,"phases":4,"briefSummary":142,"conditions":143,"keywords":149,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":157,"lastUpdatePostDateStruct":158,"startDateStruct":160,"completionDateStruct":162,"leadSponsor":164,"locationsCount":48},"100627135","erectile-function-after-pci-in-mi-and-non-mi-patients-100627135","NCT07444697","\"Erectile Function After PCI in MI and Non-MI Patients\"","Erectile Function After Percutaneous Coronary Intervention in Myocardial Infarction and Non-Infarction Patients: A Prospective Comparative Study.","ERECT-PCI","Inclusion Criteria\n\n* Male patients aged 30-75 years\n* Undergoing successful percutaneous coronary intervention (PCI) for one of the following:\n\n  * Acute myocardial infarction (Group 1)\n  * Stable angina (Group 2)\n* Hemodynamically stable after the PCI procedure\n* Survival of the index hospitalization\n* Ability to provide written informed consent\n* Sexually active within the 3 months prior to enrollment\n* Willingness and ability to complete follow-up visits and questionnaires at:\n\n  * Baseline (post-PCI recovery)\n  * 3 months\n  * 6 months Exclusion Criteria\n* Known malignancy (active or recently treated)\n* Neurological disorders affecting erectile function, including:\n\n  * Spinal cord injury\n  * Multiple sclerosis\n  * Parkinson's disease\n* Uncontrolled diabetes mellitus (HbA1c \\> 9%)\n* Presence of more than two chronic systemic diseases, such as:\n\n  * Severe renal disease\n  * Severe hepatic disease\n  * Severe pulmonary disease\n* Polypharmacy, defined as chronic use of more than three daily medications\n* Absence of sexual activity or lack of a sexual partner\n* Refusal or inability to provide informed consent or complete study questionnaires\n* Severe psychiatric illness interfering with study participation\n* Endocrine disorders, including:\n\n  * Untreated hypogonadism\n  * Thyroid disease\n* Major post-PCI complications preventing participation, including:\n\n  * Reinfarction\n  * Stroke\n  * Heart failure","30 Years","75 Years",{"count":140,"type":22},100,"6 Months","The goal of this observational study is to assess changes in patients' erectile function after percutaneous coronary intervention (PCI) using a standard IIEF (International Index of Erectile Function) questionnaire at 1, 3, and 6 months post-PCI. By doing this, we try to compare patients' responses to PCI after having a heart attack and stable angina to see the real effect of myocardial infarction on erectile function status in the long term by comparing it with a very similar group.",[144,145,146,147,148],"Erectile Disfunction","Coronary Artery Disease (CAD)","Diabete Mellitus","Anxiety","Depression and Quality of Life",[150,151,152,153,154,155,156],"erectile disfunction","coronary artery disease","Syntax score","percutaneous coronary intervention","anxiety","Fear","angina","2026-02-24",{"date":159,"type":40},"2026-03-03",{"date":161,"type":40},"2026-01-15",{"date":163,"type":22},"2026-11",{"name":46,"class":47},{"id":166,"slug":167,"hasResults":11,"nctId":168,"briefTitle":169,"officialTitle":170,"acronym":4,"eligibilityCriteria":171,"healthyVolunteers":16,"sex":17,"minAge":4,"maxAge":172,"enrollmentInfo":173,"targetDuration":4,"studyType":175,"phases":176,"briefSummary":178,"conditions":179,"keywords":182,"overallStatus":74,"whyStopped":4,"lastUpdateSubmitDate":187,"lastUpdatePostDateStruct":188,"startDateStruct":190,"completionDateStruct":192,"leadSponsor":194,"locationsCount":48},"100586898","the-effect-of-compassionate-care-education-on-nurses-100586898","NCT06921369","The Effect of Compassionate Care Education on Nurses","The Effect of Compassionate Care Training Given According to Watson's Human Caring Model on Nurses' Compassion Levels and Caring Behaviors","Inclusion Criteria:\n\n* Volunteering to participate in the study,\n* Understanding and using Turkish effectively,\n* Not being on leave during the study.\n\nExclusion Criteria:\n\n* Nurses who answered the data collection forms incompletely,\n* Nurses who did not want to continue the study,\n* Nurses who did not participate in even one of the compassionate care education programs of the study.","65 Years",{"count":174,"type":22},60,"INTERVENTIONAL",[177],"NA","Compassion is an important concept underlying relationships between people. Compassion is a complex, multifaceted psychological and social process. Professional values form the basis of nursing care. The concept of compassion is one of these professional values, as well as one of the essential components of care that facilitates nursing care. Compassion-based care provides patient-centered care with a holistic approach while increasing the quality of care. Despite this importance, many healthcare professionals remain inadequate regarding compassionate care. The idea that compassion is innate or learned in people causes various difficulties in teaching compassion. Compassionate care is an emotion that can be taught and developed with innovative interactive methods along with developing technology. Methods such as video-supported teaching and case analysis, which are widely used in nursing education, contribute to developing cognitive and affective skills such as interpretation, critical thinking, and problem-solving in nurses. In this context, it is aimed to implement compassionate care training, developed based on Watson's Human Caring Model, on nurses by enriching it with video-supported teaching and case analysis methods, and to evaluate the effect of this training on nurses' compassion levels and caring behaviors.",[180,181],"Nursing","Compassion",[183,184,185,186],"nursing","compassionate care","Video-assisted teaching","Caring behaviors","2025-12-13",{"date":189,"type":40},"2025-12-16",{"date":191,"type":22},"2025-12-20",{"date":193,"type":22},"2026-02-20",{"name":46,"class":47},{"id":196,"slug":197,"hasResults":11,"nctId":198,"briefTitle":199,"officialTitle":200,"acronym":4,"eligibilityCriteria":201,"healthyVolunteers":16,"sex":17,"minAge":57,"maxAge":202,"enrollmentInfo":203,"targetDuration":4,"studyType":24,"phases":4,"briefSummary":205,"conditions":206,"keywords":211,"overallStatus":74,"whyStopped":4,"lastUpdateSubmitDate":219,"lastUpdatePostDateStruct":220,"startDateStruct":222,"completionDateStruct":224,"leadSponsor":226,"locationsCount":4},"100588191","comparison-of-aquaporin--4--5--9-and-il-8-levels-in-gcf-dentin-fluid-and-pulp-samples-100588191","NCT06938191","Comparison of Aquaporin -4, -5, -9 and IL-8 Levels in GCF, Dentin Fluid and Pulp Samples","Comparison of Aquaporin -4, -5, -9 and IL-8 Levels in Gingival Crevicular Fluid, Dentin Fluid and Pulp Samples of Healthy and Acute Irreversible Pulpitis Teeth","Inclusion Criteria:\n\n* Patients aged 18 to 64 years.\n* Patients without any known systemic disease.\n* Patients requiring root canal treatment for prosthetic purposes (Healthy pulp group).\n* Patients with third molars (wisdom teeth) indicated for extraction due to orthodontic or other clinical reasons (Healthy pulp group).\n* Patients diagnosed with symptomatic irreversible pulpitis based on the criteria established by the American Association of Endodontists (AAE) (Symptomatic irreversible pulpitis group).\n* Patients scheduled for routine root canal treatment at the Department of Endodontics, Faculty of Dentistry, Kırıkkale University.\n* Patients who have provided written informed consent to participate in the study.\n\nExclusion Criteria:\n\n* Patients with any known systemic disease.\n* Pregnant women or those suspected of being pregnant.\n* Patients who have used antibiotics, anti-inflammatory drugs, or antidepressants within the past 4 weeks.\n* Patients with significant dental plaque or calculus, gingival redness or bleeding, severe gingivitis, generalized periodontitis, or periodontal pockets deeper than 4 mm.\n* Patients with teeth showing internal or external root resorption.\n* Patients for whom complete rubber dam isolation cannot be achieved.\n* Patients with teeth exhibiting signs of necrosis, apical lesions, swelling, or presence of a sinus tract.\n* Patients with immature teeth presenting open apices.\n* Patients with third molars (wisdom teeth) that are not fully erupted or have been previously diagnosed with pericoronitis.","64 Years",{"count":204,"type":22},70,"This study aimed to compare the changes in AQP -4, -5, -9, and IL-8 levels in pulp tissue, GCF, and dentin fluid samples routinely obtained during the treatment of healthy and symptomatic teeth diagnosed with irreversible pulpitis and investigate whether there is a correlation between them.\n\nA total of 70 patients aged 18-64 years with healthy (Group 1) and symptomatic irreversible pulpitis (Group 2) diagnosed at Kırıkkale University, Faculty of Dentistry, Department of Endodontics who will undergo routine root canal treatment will be included in the study, with a minimum of 35 participants for each group. Before starting treatment, DOS samples will be taken from healthy, symptomatic, irreversible pulpitis-diagnosed teeth and teeth contralateral to these teeth. A dentin fluid sample will be taken by holding the membrane on the dentin surface, and the pulp tissue will be removed and transferred to Eppendorf tubes. The treatment process will be completed by applying routine root canal procedures to the teeth. The samples' Aquaporin -4, -5, -9, and IL-8 levels will be analyzed by specific enzyme-linked immunosorbent assay (ELISA).",[207,208,209,210,65],"Pulpitis","Pulpitis - Irreversible","Pulp Inflammation","Healthy Pulp",[212,213,214,215,216,217,218],"healthy pulp","pulpitis","irreversible pulpitis","aquaporin-4","IL-8","aquaporin-5","aquaporin-9","2025-11-27",{"date":221,"type":40},"2025-12-01",{"date":223,"type":22},"2025-12",{"date":225,"type":22},"2026-09-12",{"name":46,"class":47},{"id":228,"slug":229,"hasResults":11,"nctId":230,"briefTitle":231,"officialTitle":232,"acronym":4,"eligibilityCriteria":233,"healthyVolunteers":11,"sex":17,"minAge":234,"maxAge":57,"enrollmentInfo":235,"targetDuration":4,"studyType":175,"phases":237,"briefSummary":238,"conditions":239,"keywords":241,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":253,"lastUpdatePostDateStruct":254,"startDateStruct":256,"completionDateStruct":258,"leadSponsor":260,"locationsCount":106},"100596443","vibration-effects-on-gait-and-balance-in-cp-100596443","NCT07045519","Vibration Effects on Gait and Balance in CP","The Acute Effects of Local Vibration Application to the Gastrocnemius Muscle on Gait and Balance in Individuals With Hemiparetic Cerebral Palsy","Inclusion Criteria:\n\n* Diagnosis of cerebral palsy, classified as GMFCS Level I or II\n* Aged between 4 and 18 years\n* Presence of spasticity in the gastrocnemius muscle (Modified Ashworth Scale score of 1, 1+, or 2)\n* Able to walk independently\n* Ability to follow verbal instructions\n* No botulinum toxin injection in the past 3 months\n* No lower limb surgery in the past 6 months\n* Voluntary participation with written and verbal informed consent obtained from parents or legal guardians\n\nExclusion Criteria:\n\n* Botulinum toxin injection or surgical intervention for spasticity within the past 6 months\n* Neurological disorders other than cerebral palsy\n* Musculoskeletal problems that may affect standing or walking (e.g., joint pain, lower extremity fractures within the past 6 months)\n* Severe cognitive impairment preventing understanding of basic commands\n* Behavioral problems or poor cooperation that interfere with assessments\n* Lack of written informed consent from parents or legal guardians","4 Years",{"count":236,"type":22},40,[177],"This randomized controlled study aims to investigate the acute effects of local vibration applied to the spastic medial gastrocnemius muscle on balance and spatiotemporal gait parameters in children with hemiparetic cerebral palsy. Children aged 4 to 18 years with spasticity levels of 1 to 2 on the Modified Ashworth Scale and Gross Motor Function Classification System (GMFCS) levels I-II will be included. Participants will be randomly assigned to either a treatment group receiving local vibration or a placebo group. Assessments will be conducted before, immediately after, and 30 minutes after the intervention. Balance will be assessed using the Timed Up and Go Test (TUG), Pediatric Reach Test, Tandem Stance Test, and Pediatric Berg Balance Scale. Spatiotemporal gait parameters will be measured using a digital gait analysis system. The results will provide insights into the immediate effectiveness of localized vibration therapy in pediatric cerebral palsy rehabilitation.",[240],"Cerebral Palsy Hemiparetic Cerebral Palsy Spasticity Gait Disorders, Neurologic Postural Balance Impairment",[242,243,244,245,246,247,248,249,250,251,252],"Hemiparetic Cerebral Palsy","Randomized Controlled Trial","Modified Ashworth Scale","Tardieu Scale","Gross Motor Function","Pediatric Physiotherapy","Gait Analysis","Balance Assessment","Gastrocnemius Muscle","Spasticity","Local Vibration Therapy","2025-08-28",{"date":255,"type":40},"2025-08-29",{"date":257,"type":40},"2025-06-29",{"date":259,"type":22},"2026-03-29",{"name":46,"class":47},{"id":262,"slug":263,"hasResults":11,"nctId":264,"briefTitle":265,"officialTitle":266,"acronym":4,"eligibilityCriteria":267,"healthyVolunteers":16,"sex":17,"minAge":57,"maxAge":58,"enrollmentInfo":268,"targetDuration":4,"studyType":24,"phases":4,"briefSummary":269,"conditions":270,"keywords":274,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":253,"lastUpdatePostDateStruct":279,"startDateStruct":280,"completionDateStruct":282,"leadSponsor":284,"locationsCount":48},"100592543","validity-and-reliability-of-gait-and-jump-parameters-measured-by-the-isen-device-in-healthy-adults-100592543","NCT06994793","Validity and Reliability of Gait and Jump Parameters Measured by the iSen Device in Healthy Adults","Investigation of the Validity and Reliability of Gait and Jumping Parameters Measured With iSen Device in Healthy Adults","Inclusion Criteria:\n\n* Age between 18 and 35 years. Voluntarily agree to participate in the study. No history of surgery in the lower extremities.\n\nExclusion Criteria:\n\n* Any musculoskeletal, neurological, or systemic pathology that could affect gait or jumping performance.\n\nInability to comply with study procedures.",{"count":174,"type":22},"This study aims to evaluate the validity and reliability of gait and jumping parameters measured with the iSen device in healthy adults. Gait analysis is a valuable tool for assessing general health, cognitive performance, quality of life, and mortality. It is commonly used by clinicians to assess functional limitations resulting from neurological or orthopedic conditions and to guide treatment plans. Traditional gait assessments primarily focus on walking speed, but additional parameters such as step length, step time, and gait symmetry are crucial for a comprehensive analysis.\n\nThe study will also assess vertical jump performance, which is a surrogate measure of explosive lower limb strength and is commonly used in sports performance and injury prediction. The iSen device, a wearable and affordable sensor, will be compared to the validated BTS G-Walk system to evaluate the accuracy and consistency of its measurements. Participants aged 18-35 with no history of musculoskeletal, neurological, or systemic conditions will be included.\n\nThe study will be conducted at Gazi University and Kırıkkale University, where participants will undergo assessments of gait and jump performance using both iSen and BTS G-Walk devices. A test-retest reliability protocol will be employed with a seven-day interval between measurements. The results will provide evidence on the suitability of the iSen device for reliable and valid gait and jump measurements in clinical settings",[271,248,272,273],"Healthy Adults","Jumping Performance","Reliability and Validity",[248,272,275,276,277,278],"iSen Device","Wearable Sensors","Reliability","Validity",{"date":255,"type":40},{"date":281,"type":40},"2025-01-10",{"date":283,"type":22},"2026-02-01",{"name":46,"class":47},{"id":286,"slug":287,"hasResults":11,"nctId":288,"briefTitle":289,"officialTitle":290,"acronym":291,"eligibilityCriteria":292,"healthyVolunteers":16,"sex":17,"minAge":293,"maxAge":57,"enrollmentInfo":294,"targetDuration":4,"studyType":175,"phases":295,"briefSummary":296,"conditions":297,"keywords":301,"overallStatus":74,"whyStopped":4,"lastUpdateSubmitDate":308,"lastUpdatePostDateStruct":309,"startDateStruct":311,"completionDateStruct":313,"leadSponsor":315,"locationsCount":48},"100600258","effects-of-neuroathletic-training-on-judokas-physical-cognitive-and-performance-abilities-100600258","NCT07095153","Effects of Neuroathletic Training on Judokas' Physical, Cognitive, and Performance Abilities","Examining the Effects of a Neuroathletic Training Program on the Physical, Cognitive, and Performance Abilities of Judokas","NAT-Judo","Inclusion Criteria:\n\n* Aged between 10 and 18 years\n* Practicing judo regularly for at least 1 year\n* Attended a minimum of 3 training sessions per week for the last 6 months\n* Holding an active competitive license\n* Medically cleared for sports participation\n* No musculoskeletal restrictions that limit physical activity\n* No diagnosed neurological or vestibular disorders\n* Cognitive ability to understand and follow test procedures\n* Written informed consent provided by parent\u002Flegal guardian (for participants under 18)\n* Commitment to regular participation throughout the study duration\n\nExclusion Criteria:\n\n* Individuals diagnosed with attention deficit, hyperactivity disorder, or difficulty maintaining attention during training\n* Individuals using medications targeting balance, visual, or vestibular systems\n* Participation in any other scientific study simultaneously\n* Currently receiving psychiatric treatment or regular use of psychiatric medication\n* Previous participation in neuroathletic or similar neuromotor training programs\n* Individuals who actively resist or deliberately sabotage the NAA protocol\n* Missing two or more measurement or training sessions during the study\n* Refusal to comply with the protocol or failure to complete surveys\u002Ftests\n* Participants whose parents\u002Fguardians express concerns or refuse approval during the consent process\n* Behaviors that may jeopardize study sustainability or data integrity","10 Years",{"count":236,"type":22},[177],"The primary objective of this project is to comprehensively investigate the effects of the Neuroathletic Training (NAT) approach, integrated into the routine training program, on the physical fitness, cognitive skills, and sports performance of judokas aged 10 to 18 years. This study is designed as a randomized controlled trial involving 40 judokas randomly assigned to either the NAT group or the control group. The NAT program, implemented over eight weeks, includes exercises targeting visual-motor coordination, reaction time, balance, and proprioception. Outcome measures such as reaction time, agility, balance, flexibility, proprioception, attention, grip strength, and judo-specific physical fitness will be assessed using a pre-test and post-test design. The results are expected to contribute to the development of a novel training model aimed at enhancing judo performance and to provide original insights into the effects of neuroathletic training in sports sciences. Additionally, the NAT protocol aims to improve not only physical fitness parameters but also cognitive domains such as mental flexibility, decision-making speed, and concentration by enhancing neuromotor control parameters including balance, coordination, reaction time, and attention.",[298,299,300],"Neuroathletic Training","Exercise","Athletic Performance",[302,303,304,305,306,307],"Neuroathletic training","Judo","Physical fitness","Cognitive performance","Sport performance","Exercise therapy","2025-07-23",{"date":310,"type":40},"2025-07-31",{"date":312,"type":22},"2025-09",{"date":314,"type":22},"2026-05",{"name":46,"class":47},{"id":317,"slug":318,"hasResults":11,"nctId":319,"briefTitle":320,"officialTitle":321,"acronym":4,"eligibilityCriteria":322,"healthyVolunteers":11,"sex":17,"minAge":57,"maxAge":138,"enrollmentInfo":323,"targetDuration":4,"studyType":24,"phases":4,"briefSummary":325,"conditions":326,"keywords":330,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":332,"lastUpdatePostDateStruct":333,"startDateStruct":335,"completionDateStruct":337,"leadSponsor":339,"locationsCount":48},"100569833","spinal-straightness-posture-and-balance-physical-performance-and-energy-consumption-in-individuals-with-stroke-100569833","NCT06699381","Spinal Straightness, Posture And Balance, Physical Performance And Energy Consumption In Individuals With Stroke","Investigation Of The Relationship Between Spinal Straightness And Posture And Balance, Physical Performance And Energy Consumption In Individuals With Stroke","Inclusion Criteria:\n\n* Individuals between the ages of 18-75 years diagnosed with stroke\n* Volunteering to participate in the study\n* Diagnosis of hemorrhagic or ischemic stroke,\n* No collaboration and communication problems\n* Can walk with assistive device or independently\n\nExclusion Criteria:\n\n* Have another neurological, cardiopulmonary or orthopedic problem other than stroke that may affect functionality, ambulation and balance\n* Patients who refused to participate in the study and did not give written consent.\n* Cooperation and communication problems were determined as",{"count":324,"type":22},30,"Patients diagnosed with ischemic or hemorrhagic stroke who applied to Kırıkkale University, Faculty of Health Sciences, Department of Physiotherapy and Rehabilitation will be included in the study. The aim of our study is to investigate the relationship between spinal alignment, posture and weight transfer symmetry with balance, physical performance and energy expenditure in stroke patients.",[327,328,329],"Stroke","Postural; Defect","Energy Supply; Deficiency",[331],"stroke,posture,balance,spinal straightness","2025-06-11",{"date":334,"type":40},"2025-06-15",{"date":336,"type":40},"2024-03-05",{"date":338,"type":22},"2025-07-05",{"name":46,"class":47},{"id":341,"slug":342,"hasResults":11,"nctId":343,"briefTitle":344,"officialTitle":345,"acronym":4,"eligibilityCriteria":346,"healthyVolunteers":16,"sex":17,"minAge":57,"maxAge":4,"enrollmentInfo":347,"targetDuration":4,"studyType":24,"phases":4,"briefSummary":349,"conditions":350,"keywords":352,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":355,"lastUpdatePostDateStruct":356,"startDateStruct":358,"completionDateStruct":360,"leadSponsor":362,"locationsCount":48},"100536057","relationship-between-respiratory-muscle-strength-balance-trunk-control-functional-capacity-in-stroke-patients-100536057","NCT06259877","Relationship Between Respiratory Muscle Strength, Balance, Trunk Control, Functional Capacity in Stroke Patients","Determination of the Relationship Between Respiratory Muscle Strength, Respiratory Functions, Balance, Trunk Control, Functional Capacity and Motor Functions in Stroke Patients and Comparison With Healthy Individuals","Inclusion Criteria:\n\n* Stroke individuals over the age of 18\n\nExclusion Criteria:\n\n* Patients with another neurological problem (Parkinson, Multiple sclerosis, etc.) that will affect functionality and balance other than stroke\n* Patients with orthopedic problems (short limbs, spine and lower extremity surgery) with pulmonary disease\n* Patients with cooperation and communication problems",{"count":348,"type":22},44,"The purpose of this study; To determine the relationship between respiratory muscle strength, balance, trunk control, functional capacity and motor functions in stroke patients and compare them with healthy individuals.",[351],"Stroke Patients",[27,353,354],"Postural Control","Balance","2025-04-27",{"date":357,"type":40},"2025-04-30",{"date":359,"type":40},"2021-03-01",{"date":361,"type":22},"2025-07-01",{"name":46,"class":47},{"id":364,"slug":365,"hasResults":11,"nctId":366,"briefTitle":367,"officialTitle":368,"acronym":4,"eligibilityCriteria":369,"healthyVolunteers":16,"sex":17,"minAge":370,"maxAge":138,"enrollmentInfo":371,"targetDuration":4,"studyType":175,"phases":373,"briefSummary":374,"conditions":375,"keywords":377,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":382,"lastUpdatePostDateStruct":383,"startDateStruct":385,"completionDateStruct":387,"leadSponsor":388,"locationsCount":106},"100563040","acute-effect-of-local-vibration-in-stroke-patients-100563040","NCT06610994","Acute Effect of Local Vibration in Stroke Patients","Investigation of the Acute Effect of Local Vibration Application on Gait and Balance in Stroke Patients","Inclusion Criteria:\n\n* 45-75 years old diagnosed with stroke\n* Being diagnosed with ischemic or hemorrhagic stroke,\n* Not having cooperation and communication problems,\n* Stroke individuals with gastrosoleus spasticity, those with a MAS score of 2 or below,\n* Those who score 0-3 on the Modified Rankin Scale.\n* People weighing less than 150 kilos\n* Patients who can walk independently (with an assisted device if they use an assistive device)\n\nExclusion Criteria:\n\n* Have undergone surgery or botox for spasticity in the last 6 months,\n* Those with joint contracture,\n* Having a neurological disease other than stroke that may affect the patient's ability to walk and stand independently, or having pain in the lower extremity joints and a history of fractures in the lower extremities in the last 6 months,\n* Having spasticity that prevents sole contact\n* Patients who do not agree to participate in the study and do not give written consent","45 Years",{"count":372,"type":22},20,[177],"The aim of the research is to examine the acute effect of local vibration application on gait and balance in stroke patients.",[376],"Acute Effect of Local Vibration Application in Stroke Patients",[378,379,380,381],"local vibration","stroke","gait","balance","2025-03-10",{"date":384,"type":40},"2025-03-11",{"date":386,"type":40},"2025-01-01",{"date":191,"type":22},{"name":46,"class":47},{"id":390,"slug":391,"hasResults":11,"nctId":392,"briefTitle":393,"officialTitle":393,"acronym":4,"eligibilityCriteria":394,"healthyVolunteers":16,"sex":17,"minAge":234,"maxAge":395,"enrollmentInfo":396,"targetDuration":4,"studyType":24,"phases":4,"briefSummary":398,"conditions":399,"keywords":4,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":281,"lastUpdatePostDateStruct":403,"startDateStruct":405,"completionDateStruct":407,"leadSponsor":409,"locationsCount":48},"100575815","evaluation-of-motor-skills-balance-dual-task-and-social-adaptation-in-individuals-with-autism-100575815","NCT06777186","Evaluation of Motor Skills, Balance, Dual Task, and Social Adaptation in Individuals with Autism","Inclusion Criteria:\n\n* Being diagnosed with ASD by a physician\n* Children are receiving education in a special education and rehabilitation center\n* No vision problems\n* Ability to receive and execute commands\n* No cognitive problems\n* No walking problems\n\nExclusion Criteria:\n\n* Individuals with concomitant secondary diseases\n* Individuals who have undergone surgery in the last six months","21 Years",{"count":397,"type":22},55,"The aim of our study is to evaluate motor skills balance, dual task and social adaptation skills in individuals with autism. Our study will be conducted in Bartın Lider Special Education and Rehabilitation Center after ethics committee approval. The sample number determined by power analysis will be included in the study. Socio-demographic characteristics (age, height, body weight, body mass index, education level, exercise and smoking habits, etc.) of the individuals who voluntarily participated in the study will be obtained. The individuals participating in the study will be divided into two groups as individuals with normal motor development and individuals with autism spectrum disorder and the same assessment scales will be used. These assessment scales are TUG, 10 meter walking test, Vineland Adaptive Adaptation Scale, Bruininks-Oseretsky Motor Competence Test. According to the evaluation results, motor skills, functional balance, dual task and social adaptation skills of individuals with autism will be compared with individuals with normal motor development.",[400,401,402],"Autism Spectrum Disorder","Motor Disorders","Social Skills",{"date":404,"type":40},"2025-01-15",{"date":406,"type":40},"2024-12-15",{"date":408,"type":22},"2025-11-25",{"name":46,"class":47},{"id":411,"slug":412,"hasResults":11,"nctId":413,"briefTitle":414,"officialTitle":415,"acronym":4,"eligibilityCriteria":416,"healthyVolunteers":16,"sex":17,"minAge":234,"maxAge":395,"enrollmentInfo":417,"targetDuration":4,"studyType":24,"phases":4,"briefSummary":419,"conditions":420,"keywords":4,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":422,"lastUpdatePostDateStruct":423,"startDateStruct":425,"completionDateStruct":427,"leadSponsor":429,"locationsCount":48},"100571503","balance-tmj-social-adaptive-assessment-in-individuals-with-autism-spectrum-disorder-100571503","NCT06721104","Balance, TMJ, Social Adaptive Assessment in Individuals With Autism Spectrum Disorder","'Evaluation of Temporomandibular Joint Dysfunction, Balance, Cervical Posture, Dual Task, and Social Adjustment in Individuals With Autism Spectrum Disorder'","Inclusion Criteria:\n\n* Having a diagnosis of Autism Spectrum Disorder (ASD) confirmed by a physician.\n* Currently enrolled in a special education and rehabilitation center.\n* No vision problems.\n* Ability to understand and follow instructions.\n* No cognitive impairments.\n* No walking difficulties.\n\nExclusion Criteria:\n\n* Individuals with comorbid secondary health conditions.\n* Individuals who have undergone surgery in the past six months.",{"count":418,"type":22},23,"The aim of our study is to evaluate temporomandibular joint (TMJ), cervical posture, balance, dual-task performance, and social adaptation skills in individuals with autism. The study will be conducted at Bartın Lider Special Education and Rehabilitation Center following the approval of the ethics committee. Individuals determined by the sample size calculated through power analysis will be included in the study. First, the socio-demographic characteristics (age, height, body weight, body mass index, education level, exercise and smoking habits, etc.) of the participants who voluntarily join the study will be recorded. Participants will be divided into two groups: individuals with typical motor development and those with autism spectrum disorder (ASD), and the same assessment tools will be used for both groups. Individuals with typical motor development will serve as the control group.\n\nThe assessment tools include the Timed Up and Go (TUG) test, the 10-Meter Walk Test, the Vineland Adaptive Behavior Scale, the PostureScreen Android-based posture assessment application, and the Helkimo Clinical Dysfunction Index for craniomandibular disorders. Based on the evaluation results, the relationships between TMJ, cervical posture, functional balance, dual-task performance, and social adaptation skills in individuals with autism will be analyzed and compared with those of individuals with typical motor development.",[400,421,328],"Temporomandibular Joint Disorders","2024-12-05",{"date":424,"type":40},"2024-12-06",{"date":426,"type":40},"2024-02-15",{"date":428,"type":22},"2025-05-25",{"name":46,"class":47},""]