[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"KBC Split\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":44},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":15,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":28,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":5},"100593565","prostaglandin-e-urinary-metabolite-pge-m-as-a-predictor-of-acute-appendicitis-in-children-100593565",false,"NCT07008092","Prostaglandin-E Urinary Metabolite (PGE-M) as a Predictor of Acute Appendicitis in Children","Inclusion Criteria:\n\n* children of age 5 -17 years with acute abdominal pain\n* children with clinical signs of acute appendicitis\n\nExclusion Criteria:\n\n* previous diagnosis of chronic and\u002For malignant disease\n* children who had previous abdominal surgery\n* pregnancy",true,"ALL","5 Years","17 Years",{"count":20,"type":21},100,"ESTIMATED","OBSERVATIONAL","Diagnosing acute appendicitis in children remains a clinical challenge, with delayed or incorrect diagnosis potentially leading to serious complications or unnecessary surgery. Prostaglandin E urinary metabolites (PGE-M) have been found elevated in various inflammatory conditions, but their diagnostic value in pediatric appendicitis is not well established. This study aims to assess the potential of PGE-M as a biomarker for acute appendicitis in children.\n\nThe study will be conducted over 12 months and will include 100 children aged 5 to 17 years presenting with acute abdominal pain. In addition to routine laboratory tests, urinary PGE-M levels will be analyzed. The study involves minimal risk to participants",[25,26,27],"Acute Appendicitis","Acute Appendicitis With Rupture","Abdominal Pain (AP)",[29,30,31],"Acute appendicitis","PGE-M","Prostaglandin-E urinary metabolite","RECRUITING","2025-05-29",{"date":35,"type":36},"2025-06-06","ACTUAL",{"date":38,"type":21},"2025-06-02",{"date":40,"type":21},"2026-05-01",{"name":42,"class":43},"KBC Split","OTHER",""]