[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Kafrelsheikh University\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":582},{"pageToken":4,"total":5,"offset":6,"count":7,"results":8},null,85,0,25,[9,41,63,88,110,136,159,179,201,221,238,261,286,305,331,353,384,405,426,450,473,493,513,533,561],{"id":10,"slug":11,"hasResults":12,"nctId":13,"briefTitle":14,"officialTitle":15,"acronym":4,"eligibilityCriteria":16,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":4},"100644287","laser-vs-lontophoresis-in-koa-100644287",false,"NCT07666061","Laser vs Lontophoresis in KOA","Effectiveness of Laser Therapy Versus Lontophoresis in the Management of Knee Osteoarthritis: A Randomized Controlled Trial","Inclusion Criteria:\n\n* \\* Age 45-65 years.\n\n  * Diagnosed primary knee osteoarthritis (Grade I-II).\n  * Both genders.\n  * Ability to follow treatment protocol.\n\nExclusion Criteria:\n\n* \\* Previous knee surgery.\n\n  * Intra-articular injections within last 6 months.\n  * Pacemaker.\n  * Skin lesions at treatment area.\n  * Severe neurological or cardiovascular disorders.","ALL","45 Years","65 Years",{"count":21,"type":22},66,"ESTIMATED","INTERVENTIONAL",[25],"NA","This randomized controlled trial aims to compare the effectiveness of laser therapy and iontophoresis in patients with knee osteoarthritis. The study will evaluate pain reduction, functional improvement, and knee joint mobility following",[28],"Knee Arthritis Osteoarthritis","NOT_YET_RECRUITING","2026-06-18",{"date":32,"type":33},"2026-06-24","ACTUAL",{"date":35,"type":22},"2026-08-01",{"date":37,"type":22},"2027-04-01",{"name":39,"class":40},"Kafrelsheikh University","OTHER",{"id":42,"slug":43,"hasResults":12,"nctId":44,"briefTitle":45,"officialTitle":46,"acronym":47,"eligibilityCriteria":48,"healthyVolunteers":12,"sex":17,"minAge":49,"maxAge":50,"enrollmentInfo":51,"targetDuration":4,"studyType":23,"phases":53,"briefSummary":54,"conditions":55,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":57,"lastUpdatePostDateStruct":58,"startDateStruct":60,"completionDateStruct":61,"leadSponsor":62,"locationsCount":4},"100642295","eswt-vs-hilt-in-chronic-lateral-epicondylitis-100642295","NCT07654790","ESWT vs HILT in Chronic Lateral Epicondylitis","Effectiveness of Shockwave Therapy Versus High-Power Laser Therapy in the Management of Chronic Lateral Epicondylitis: A Double-Blind Randomized Controlled Trial","ESWT vs HILT","Inclusion Criteria:\n\n* • Age 40-50 years.\n\n  * Clinically diagnosed chronic lateral epicondylitis.\n  * Symptoms lasting more than 3 months.\n  * Positive clinical provocation tests.\n  * Localized tenderness over the lateral epicondyle.\n\nExclusion Criteria:\n\n* • Previous elbow surgery.\n\n  * Corticosteroid injection within the last 6 months.\n  * Cervical radiculopathy.\n  * Peripheral nerve entrapment.\n  * Rheumatologic or systemic inflammatory disorders.\n  * Elbow fracture.\n  * Severe elbow instability","40 Years","50 Years",{"count":52,"type":22},72,[25],"This randomized controlled trial aims to compare the effectiveness of Extracorporeal Shock Wave Therapy (ESWT) and High-Intensity Laser Therapy (HILT) in patients with chronic lateral epicondylitis.",[56],"Chronic Lateral Epicondylitis","2026-06-12",{"date":59,"type":33},"2026-06-17",{"date":35,"type":22},{"date":37,"type":22},{"name":39,"class":40},{"id":64,"slug":65,"hasResults":12,"nctId":66,"briefTitle":67,"officialTitle":67,"acronym":4,"eligibilityCriteria":68,"healthyVolunteers":12,"sex":69,"minAge":70,"maxAge":71,"enrollmentInfo":72,"targetDuration":4,"studyType":23,"phases":74,"briefSummary":76,"conditions":77,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":79,"lastUpdatePostDateStruct":80,"startDateStruct":82,"completionDateStruct":84,"leadSponsor":86,"locationsCount":87},"100637912","phase-2-letrozole-versus-methotrexate-for-management-of-undisturbed-ectopic-pregnancy-100637912","NCT07624903","Letrozole Versus Methotrexate for Management of Undisturbed Ectopic Pregnancy","Inclusion Criteria:\n\n* Confirmed ectopic pregnancy on trans vaginal ultrasound\n* Age between 20 and 35 years\n* A β-hCG levels \\\u003C 3000 Iu\u002F L\n* The average diameter of the adnexal mass ≤3.5 cm\n* Stable hemodynamic condition\n\nExclusion Criteria:\n\n* Presence of fetal heart pulsation\n* Heterotopic pregnancy\n* Presence of significant abdominal pain\n* history of allergic reactions to MTX or letrozole\n* Any known liver disorder or abnormal liver enzyme levels (AST or ALT )\n* Any known renal disorder or impaired renal function tests (abnormal creatinine)","FEMALE","20 Years","35 Years",{"count":73,"type":22},70,[75],"PHASE2","The aim of work is to study the effectiveness of letrozole in treatment of early undisturbed ectopic pregnancy in comparison with Methotrexate.",[78],"Ectopic Pregnancy","2026-05-30",{"date":81,"type":33},"2026-06-03",{"date":83,"type":22},"2026-06",{"date":85,"type":22},"2027-07",{"name":39,"class":40},1,{"id":89,"slug":90,"hasResults":12,"nctId":91,"briefTitle":92,"officialTitle":93,"acronym":4,"eligibilityCriteria":94,"healthyVolunteers":12,"sex":17,"minAge":95,"maxAge":96,"enrollmentInfo":97,"targetDuration":4,"studyType":23,"phases":99,"briefSummary":100,"conditions":101,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":103,"lastUpdatePostDateStruct":104,"startDateStruct":106,"completionDateStruct":107,"leadSponsor":109,"locationsCount":4},"100637825","hilt-vs-eswt-in-supraspinatus-tendinitis-100637825","NCT07615920","HILT vs ESWT in Supraspinatus Tendinitis","Comparative Effectiveness of High-Intensity Laser Therapy Versus Extracorporeal Shock Wave Therapy in Patients With Supraspinatus Tendinitis","Inclusion Criteria:\n\n* Male and female participants aged between 18 and 60 years.\n* Clinically diagnosed supraspinatus tendinitis confirmed by ultrasound imaging.\n* Shoulder pain duration greater than 3 months.\n* Ability to understand and follow study instructions.\n* Willingness to participate and provide informed consent.\n\nExclusion Criteria:\n\n* Full-thickness rotator cuff tear.\n* Previous shoulder surgery.\n* Pregnancy.\n* Neurological disorders affecting the upper limb.\n* Corticosteroid injection within the previous 3 months.\n* Shoulder fracture or dislocation.\n* Systemic inflammatory diseases.\n* Participation in other physical therapy programs during the study period","18 Years","60 Years",{"count":98,"type":22},48,[25],"This randomized controlled trial aims to compare the effectiveness of High-Intensity Laser Therapy (HILT) and Extracorporeal Shock Wave Therapy (ESWT) in patients with supraspinatus tendinitis.",[102],"Supraspinatus Tendinitis","2026-05-25",{"date":105,"type":33},"2026-05-29",{"date":35,"type":22},{"date":108,"type":22},"2027-12-30",{"name":39,"class":40},{"id":111,"slug":112,"hasResults":12,"nctId":113,"briefTitle":114,"officialTitle":115,"acronym":116,"eligibilityCriteria":117,"healthyVolunteers":12,"sex":17,"minAge":95,"maxAge":118,"enrollmentInfo":119,"targetDuration":4,"studyType":23,"phases":121,"briefSummary":122,"conditions":123,"keywords":125,"overallStatus":127,"whyStopped":4,"lastUpdateSubmitDate":128,"lastUpdatePostDateStruct":129,"startDateStruct":131,"completionDateStruct":133,"leadSponsor":135,"locationsCount":87},"100621264","th-study-wants-to-compare-the-best-technique-for-sinus-operation-in-crswnp-100621264","NCT07368361","Th Study Wants to Compare the Best Technique for Sinus Operation in CRSWNP","\"Comparative Outcomes of Mucosal Reset (Reboot) Versus Complete Sinusotomy (Full House FESS) in CRSwNP: A Prospective Study","REBOOT","Inclusion Criteria:Patients above the age of 18 years presenting with recurrent refractory CRSwNP (failed ≥1 biologic\u002Fprior FESS), Type-2 endotype confirmation (blood\u002Ftissue eosinophilia, IgE ≥100 IU\u002FmL), Lund-Mackay CT score ≥10 will be included in the study.\n\nExclusion Criteria:\n\neosinophilic granulomatosis with polyangiitis (EGPA) or severe systemic diseases (except controlled asthma or NSAID-exacerbated respiratory disease), neoplasms, vasoconstrictor abuse (e.g., oxymetazoline dependence), unilateral nasal inflammatory disease, bilateral inflammatory disease without polyps, or treatment with monoclonal antibodies in the past 12 months, Patients younger than 18 years of age and patients are unfit for general anesthesia.","75 Years",{"count":120,"type":22},40,[25],"This randomized controlled trial aims to compare the efficacy and safety of reboot surgery versus conventional full house FESS in patients with refractory CRSwNP, focusing on:\n\n1\\. Primary Outcome:\n\n* Compare 24-month recurrence rates (defined as endoscopic polyp score ≥2) 2. Secondary Outcomes:\n* Recurrence-free survival (time to first recurrence), Quality of life improvement (SNOT-22 scores), Reduction in systemic corticosteroid use, Complication rates (synechiae, bleeding, infection) and Cost-effectiveness of each approach",[124],"CRSWNP",[126],"REBOOT, SINUSOTOMY, FULL HOUSE FESS, CRSWNP","RECRUITING","2026-05-23",{"date":130,"type":33},"2026-05-28",{"date":132,"type":33},"2026-01-01",{"date":134,"type":22},"2026-09-01",{"name":39,"class":40},{"id":137,"slug":138,"hasResults":12,"nctId":139,"briefTitle":140,"officialTitle":140,"acronym":141,"eligibilityCriteria":142,"healthyVolunteers":12,"sex":17,"minAge":95,"maxAge":143,"enrollmentInfo":144,"targetDuration":4,"studyType":23,"phases":146,"briefSummary":147,"conditions":148,"keywords":150,"overallStatus":127,"whyStopped":4,"lastUpdateSubmitDate":128,"lastUpdatePostDateStruct":152,"startDateStruct":154,"completionDateStruct":156,"leadSponsor":158,"locationsCount":87},"100621263","evaluation-of-internal-nasal-splint-supported-free-graft-versus-nasoseptal-flap-for-endoscopic-skull-base-repair-in-cerebrospinal-fluid-leaks-100621263","NCT07368348","Evaluation of Internal Nasal Splint-Supported Free Graft Versus Nasoseptal Flap for Endoscopic Skull Base Repair in Cerebrospinal Fluid Leaks","CSF","Inclusion Criteria: 1- Adults (≥18 years). 2- Patients with bilateral CSF leaks confirmed by imaging and biochemical testing (e.g., beta-2 transferrin).\n\n3- Patients with bilateral CSF leak and sever septal spur. 4- Patients with bilateral CSF leak and history of submucosal resection of nasal septum.\n\n5- Patients with bilateral CSF leak and large septal perforation. 6- Patients with bilateral CSF Leak and septal granuloma.\n\nExclusion Criteria: 1- Patients with contraindications to endoscopic surgery. 2- Active sinus or nasal infections. 3- Previous nasal or skull base surgery affecting the repair site.\n\n\\-","70 Years",{"count":145,"type":22},20,[25],"The study aims to compare the feasibility and effectiveness of using an internal nasal splint- supported free graft versus a nasoseptal flap alone for endoscopic repair of bilateral CSF leaks.\n\nResearch question:\n\nDoes the use of an internal nasal splint to support a free graft during endoscopic repair of bilateral CSF leaks improve outcomes compared to the use of a nasoseptal flap alone?",[149],"CSF Leak",[151],"CSF, Stent",{"date":153,"type":33},"2026-05-27",{"date":155,"type":33},"2026-02-01",{"date":157,"type":22},"2026-11-01",{"name":39,"class":40},{"id":160,"slug":161,"hasResults":12,"nctId":162,"briefTitle":163,"officialTitle":163,"acronym":4,"eligibilityCriteria":164,"healthyVolunteers":12,"sex":69,"minAge":71,"maxAge":165,"enrollmentInfo":166,"targetDuration":4,"studyType":23,"phases":168,"briefSummary":169,"conditions":170,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":172,"lastUpdatePostDateStruct":173,"startDateStruct":175,"completionDateStruct":176,"leadSponsor":178,"locationsCount":4},"100639846","total-laparoscopic-hysterectomy-with-prior-uterine-artery-cauterization-from-the-origin-versus-conventional-laparoscopic-hysterectomy-100639846","NCT07601971","Total Laparoscopic Hysterectomy With Prior Uterine Artery Cauterization From the Origin Versus Conventional Laparoscopic Hysterectomy","Inclusion Criteria: Age of the patient is more than 35 y . Non malignant pathologies including fibroids, endometrial hyperplasia, Dysfunctional Uterine bleeding not responding to medical treatment.\n\nGood general condition of the patient ( American society of Anesthesiologists \"ASA\" score 1 , 2 , 3 ( Horvath et al ,. 2021) .\n\nUterine size is less than 20 weeks by fundal level . -\n\nExclusion Criteria:Age of the patient is less than 35 y . Gynecological malignancies . Contraindications for laparoscopy as any medical condition worsens by peumo peritoneum or Trendelenburg position as severely compromised cardiopulmonary status .\n\nPatients with American society of Anesthesiologists score 4 or more . ( Horvath et al ,. 2021) Uterine size is more than 20 weeks by fundal level .\n\n\\-","55 Years",{"count":167,"type":22},44,[25],"The main goal of this study is to compare between total Laparoscopic hysterectomy proceeded by Uterine artery cauterization at its origin and conventional total Laparoscopic hysterectomy regarding: bleeding , operative time , intra operative time and follow up post operative.",[171],"Laparoscopic Hysterectomy","2026-05-15",{"date":174,"type":33},"2026-05-22",{"date":172,"type":22},{"date":177,"type":22},"2027-06-15",{"name":39,"class":40},{"id":180,"slug":181,"hasResults":12,"nctId":182,"briefTitle":183,"officialTitle":184,"acronym":4,"eligibilityCriteria":185,"healthyVolunteers":186,"sex":69,"minAge":95,"maxAge":49,"enrollmentInfo":187,"targetDuration":4,"studyType":189,"phases":4,"briefSummary":190,"conditions":191,"keywords":4,"overallStatus":127,"whyStopped":4,"lastUpdateSubmitDate":193,"lastUpdatePostDateStruct":194,"startDateStruct":196,"completionDateStruct":198,"leadSponsor":200,"locationsCount":87},"100618788","uterine-artery-doppler-indices-and-uterocervical-angle-measurment-in-prediction-of-preterm-labor-100618788","NCT07336173","Uterine Artery Doppler Indices and Uterocervical Angle Measurment in Prediction of Preterm Labor","Role of Uterine Artery Doppler Indices and Sonographic Measurement of Uterocervical Angle in Predicting Preterm Labor","Inclusion Criteria:\n\n1. Patient who will give verbal \\& written will informed consent.\n2. Pregnant women between 18 and 40 years old of age\n3. Singleton pregnancy\n4. Gestational age will be confirmed by first trimester ultrasound scan (\\\u003C14 weeks).\n5. Gestational age between 24 and 34 weeks .\n6. Threatened preterm labor which is defined as:\n\nPresence of at least one uterine contraction every 10 minutes lasting ≥30 seconds . Cervical dilatation ≤3 cm . Cervical effacement \\\u003C80%.\n\nExclusion Criteria:\n\nObstetric:\n\n1. Ruptured membranes\n2. Clinical evidence of Chorioamnionitis.\n3. Fetal compromise on evaluation.\n4. Severe obstetric complications (e.g., severe Preeclampsia, Eclampsia).\n5. Diagnosed intrauterine growth restriction (IUGR).\n6. Congenital fetal anomalies.\n7. Multiple pregnancies.\n8. Prior cervical surgery (e.g., cone biopsy, cerclage).\n\nNon-Obstetric:\n\n1. Significant maternal medical disorders (e.g., chronic hypertension, diabetes mellitus, liver dysfunction).\n2. Severe non-obstetric complications (e.g., acute abdomen).",true,{"count":188,"type":22},47,"OBSERVATIONAL","The goal of this observational study is to evaluate the role of uterine artery doppler indices and uterocervical angle measurement in prediction of preterm labor .The main question it aims to answer is:\n\nDoes combination of both uterine artery doppler indices and uterocervical angle measurement increase sensitivity and specificity for prediction of established preterm labor ? Participants already performing uterine artery doppler as part of their regular antenatal care .measurement of anterior uterocervical angle will be added between 24 to 34 weeks gestation to predict preterm labor in candidates .",[192],"Preterm Labor","2026-05-14",{"date":195,"type":33},"2026-05-18",{"date":197,"type":33},"2026-01-15",{"date":199,"type":22},"2026-08",{"name":39,"class":40},{"id":202,"slug":203,"hasResults":12,"nctId":204,"briefTitle":205,"officialTitle":206,"acronym":4,"eligibilityCriteria":207,"healthyVolunteers":186,"sex":17,"minAge":70,"maxAge":18,"enrollmentInfo":208,"targetDuration":4,"studyType":23,"phases":210,"briefSummary":211,"conditions":212,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":214,"lastUpdatePostDateStruct":215,"startDateStruct":217,"completionDateStruct":218,"leadSponsor":220,"locationsCount":87},"100639381","immediate-implant-placement-with-subepithelial-connective-tissue-grafting-and-probiotics-100639381","NCT07596758","Immediate Implant Placement With Subepithelial Connective Tissue Grafting and Probiotics","Comparative Evaluation of Platelet-Rich Fibrin Versus Probiotics as Adjuncts to Immediate Implant Placement Combined With Subepithelial Connective Tissue Grafting: Clinical, Biological, and Radiographic Peri-Implant Tissue Outcomes A Parallel-Arm Randomized Trial","Inclusion Criteria:\n\n* Adults aged 20 to 45 years.\n* Systemically healthy patients eligible for implant surgery.\n* Patients requiring extraction of a single non-restorable tooth indicated for immediate implant placement.\n* Implant sites located in the maxillary esthetic or para-esthetic zone.\n* Sites with sufficient apical and\u002For palatal bone to permit correct three-dimensional implant positioning and achieve adequate primary stability.\n* Sites suitable for simultaneous subepithelial connective tissue grafting.\n* Patients with acceptable oral hygiene and good compliance with periodontal and implant treatment.\n* Patients willing to attend all follow-up visits and comply with study instructions.\n\nExclusion Criteria:\n\n* Medically compromised patients or patients with systemic conditions that may contraindicate implant surgery or interfere with healing.\n* Smokers.\n* Pregnant or lactating women.\n* Patients with uncontrolled periodontal disease or poor oral hygiene.\n* Patients with acute infection at the intended implant site.\n* Patients with insufficient bone volume preventing immediate implant placement with adequate primary stability.\n* Patients with a history of head and neck radiotherapy or chemotherapy.\n* Patients receiving bisphosphonates or other medications known to affect bone metabolism or soft tissue healing.\n* Patients with parafunctional habits that may jeopardize implant stability or restorative success.\n* Patients unwilling or unable to complete the follow-up period.",{"count":209,"type":22},22,[25],"The present study aims to evaluate and compare the clinical, radiographic, and biological peri-implant tissue outcomes of platelet-rich fibrin versus probiotics as adjuncts to immediate implant placement combined with subepithelial connective tissue grafting in adults requiring single immediate implant placement.",[213],"Dental Implant Failed","2026-05-13",{"date":216,"type":33},"2026-05-19",{"date":193,"type":22},{"date":219,"type":22},"2027-05-30",{"name":39,"class":40},{"id":222,"slug":223,"hasResults":12,"nctId":224,"briefTitle":225,"officialTitle":226,"acronym":4,"eligibilityCriteria":227,"healthyVolunteers":186,"sex":17,"minAge":70,"maxAge":50,"enrollmentInfo":228,"targetDuration":4,"studyType":23,"phases":230,"briefSummary":231,"conditions":232,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":214,"lastUpdatePostDateStruct":233,"startDateStruct":234,"completionDateStruct":236,"leadSponsor":237,"locationsCount":87},"100638213","guided-modified-socket-shield-with-hyaluronic-acid-for-black-triangle-management-100638213","NCT07586228","Guided Modified Socket Shield With Hyaluronic Acid for Black Triangle Management","Hyaluronic Acid With AI-Guided Immediate Implant Placement Using a Modified Socket Shield for Black Triangle Management: A Randomized Controlled Clinical Trial","Inclusion Criteria:\n\n* Adults (20-50) years old.\n* Single rooted maxillary anterior teeth with hopeless prognosis.\n* Periodontally compromised but with \\>50% remaining bone.\n* Presence of black triangle ≥2 mm.\n* Systemically healthy.\n\nExclusion Criteria:\n\n* Medically compromised patients and systemic conditions that complicate implant placement as uncontrolled diabetes, osteoporosis.\n* Alcoholic and Smokers patients.\n* Pregnant or lactating women.\n* Acute Pathology or infection at implant site\n* Patients with a history of chemotherapy, radiotherapy in head and\u002For neck region.\n* Patients on bisphosphonate or steroids therapy.",{"count":229,"type":22},32,[25],"The Primary aim of this study will be to evaluate the clinical, esthetic, and radiographic outcomes of hyaluronic acid combined with immediate implant placement using AI-assisted and computer guided modified socket shield technique in maxillary anterior sites exhibiting black triangles.",[213],{"date":172,"type":33},{"date":235,"type":22},"2026-05-10",{"date":177,"type":22},{"name":39,"class":40},{"id":239,"slug":240,"hasResults":12,"nctId":241,"briefTitle":242,"officialTitle":243,"acronym":244,"eligibilityCriteria":245,"healthyVolunteers":12,"sex":17,"minAge":246,"maxAge":19,"enrollmentInfo":247,"targetDuration":4,"studyType":23,"phases":249,"briefSummary":251,"conditions":252,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":254,"lastUpdatePostDateStruct":255,"startDateStruct":257,"completionDateStruct":258,"leadSponsor":260,"locationsCount":4},"100636925","phase-2-ultrasound-guided-erectror-spinae-block-versus-intracavitary-during-medical-thoracoscopy-100636925","NCT07572019","Ultrasound Guided Erectror Spinae Block Versus Intracavitary During Medical Thoracoscopy","Ultrasound-Guided Erector Spinae Plane Block Versus Intracavitary Local Anaesthesia for Peri-procedural Analgesia During Medical Thoracoscopy: A Randomized Control Trial","ESPB","Inclusion Criteria:\n\n* 100 patients belonging to American Society of Anesthesiologists (ASA) I-III scheduled for medical thoracoscopy under adequate sedation and analgesia.\n\nExclusion Criteria:\n\n* Patients will be excluded if; history of allergy or contraindication to any of the studied drugs, BMI more than 35 kg\u002Fm2 chronic opioid use or abuse, patients for whom ESPB block is contraindicated (patient refusal, coagulation disorder, skin infection at the injection site), history of post-thoracotomy, chest wall deformity, severe uncontrolled comorbidity, intubated patients, or if the interventional physician wants general anaesthesia from the start","25 Years",{"count":248,"type":22},100,[75,250],"PHASE3","The primary aim: is to compare the effect of US guided ESP block at two levels versus intracavitary blockade in medical thoracoscopy on total peri-procedural (intraoperative and post-operative 12 hours) nalbuphine consumption (mg) during medical thoracoscopy. Secondary aims: Time to first rescue analgesia, postoperative VAS, haemodynamics, recovery time (Aldert \\> 9), and adverse events",[253],"PLEURA DISEASE","2026-05-07",{"date":256,"type":33},"2026-05-12",{"date":172,"type":22},{"date":259,"type":22},"2026-07-20",{"name":39,"class":40},{"id":262,"slug":263,"hasResults":12,"nctId":264,"briefTitle":265,"officialTitle":266,"acronym":267,"eligibilityCriteria":268,"healthyVolunteers":12,"sex":17,"minAge":95,"maxAge":19,"enrollmentInfo":269,"targetDuration":4,"studyType":23,"phases":271,"briefSummary":272,"conditions":273,"keywords":276,"overallStatus":127,"whyStopped":4,"lastUpdateSubmitDate":278,"lastUpdatePostDateStruct":279,"startDateStruct":281,"completionDateStruct":283,"leadSponsor":285,"locationsCount":87},"100636630","a-randomized-trial-of-intratympanic-drug-delivery-evaluating-the-efficacy-and-safety-of-dexamethasone-loaded-exosomes-versus-standard-therapy-in-acute-sensorineural-hearing-loss-100636630","NCT07568184","A Randomized Trial of Intratympanic Drug Delivery: Evaluating the Efficacy and Safety of Dexamethasone-Loaded Exosomes Versus Standard Therapy in Acute Sensorineural Hearing Loss.","A Phase II, Randomized Trial of Intratympanic Drug Delivery: Evaluating the Efficacy and Safety of Dexamethasone-Loaded Exosomes Versus Standard Therapy in Acute Sensorineural Hearing Loss.","EXO-DEX-SNHL","Inclusion Criteria:\n\n1. Adults aged 18-65 years.\n2. Diagnosis of idiopathic SSNHL (≥30 dB sensorineural loss at three consecutive frequencies) within 14 days of symptom onset.\n3. Failed initial standard systemic steroid therapy (e.g., oral prednisone 1 mg\u002Fkg\u002Fday for 7-14 days) or presented with contraindications to systemic steroids.\n4. Willing and able to provide written informed consent.\n\nExclusion Criteria:\n\n1. Identifiable cause of hearing loss (e.g., acoustic neuroma, Meniere's disease, trauma).\n2. Pre-existing severe to profound hearing loss in the affected ear.\n3. Active middle ear infection or tympanic membrane perforation.\n4. History of autoimmune disease, coagulation disorders, or immunodeficiency.\n5. Pregnancy or lactation.\n6. Known hypersensitivity to dexamethasone or components of the exosome formulation.\n7. Participation in another interventional clinical trial within 30 days.",{"count":270,"type":22},30,[25],"Primary Objective To compare the efficacy of a single course of IT Exo-Dex versus conventional IT dexamethasone and exosome vehicle alone, as measured by the mean change in pure-tone average (PTA; 0.5, 1, 2, 4 kHz) from baseline to the 4-week post-treatment endpoint.\n\nSecondary Objectives\n\n1. To determine the safety and tolerability profile of IT Exo-Dex.\n2. To compare the rate of hearing recovery (defined as \\>10 dB improvement in PTA or recovery to within 10 dB of contralateral ear) among the three treatment groups at 1, 4, and 12 weeks.\n3. To assess changes in auditory function via Auditory Brainstem Response (ABR) thresholds and Otoacoustic Emissions (OAEs).\n4. To characterize the pharmacokinetics and inner ear biodistribution of Exo-Dex using advanced imaging modalities (e.g., MRI with exosome-contrast agents in a sub-study cohort if applicable).",[274,275],"Sensori-Neural Deafness","Exosomes",[277],"Exosomes; SNHL; Dexamethasone","2026-05-04",{"date":280,"type":33},"2026-05-05",{"date":282,"type":33},"2026-04-03",{"date":284,"type":22},"2027-08",{"name":39,"class":40},{"id":287,"slug":288,"hasResults":12,"nctId":289,"briefTitle":290,"officialTitle":291,"acronym":4,"eligibilityCriteria":292,"healthyVolunteers":186,"sex":17,"minAge":95,"maxAge":246,"enrollmentInfo":293,"targetDuration":4,"studyType":23,"phases":294,"briefSummary":295,"conditions":296,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":298,"lastUpdatePostDateStruct":299,"startDateStruct":301,"completionDateStruct":303,"leadSponsor":304,"locationsCount":4},"100636875","stress-modulation-and-dynamic-balance-100636875","NCT07571369","Stress Modulation and Dynamic Balance","Impact of Dual Task Therapeutic Exercises on Stress Modulation and Dynamic Balance in University Students","Inclusion Criteria:\n\n* Participants will be included if they meet the following criteria:\n\nAge between 18 and 25 years. Body Mass Index (BMI) ranging from 18.5 to 29.9 kg\u002Fm². Both males and females. Apparently healthy individuals with no diagnosed neurological, musculoskeletal, or psychological disorders.\n\nAbility to understand instructions and provide informed consent. Willingness to participate and comply with the study protocol.\n\nExclusion Criteria:\n\n* Participants will be excluded if they have any of the following:\n\nAny neurological disorder affecting balance (e.g., vestibular disorders, Parkinson's disease, multiple sclerosis, peripheral neuropathy).\n\nAny recent musculoskeletal injury (within the last 6 months) affecting the lower limbs or spine.\n\nHistory of lower limb or spinal surgery. Severe visual or auditory impairment not corrected by aids. Use of medications that may affect balance or cognitive function (e.g., sedatives, antidepressants, anxiolytics, antipsychotics).\n\nPregnancy. Uncontrolled cardiovascular or respiratory disorders limiting exercise tolerance.\n\nCurrent diagnosis of major psychiatric disorders (e.g., major depression, generalized anxiety disorder, panic disorder).\n\nRegular participation in balance training, mind-body exercises (e.g., yoga, Pilates, tai chi), or structured stress management programs within the last 6 months.\n\nParticipation in another interventional study at the same time.",{"count":52,"type":22},[25],"This three-arm, parallel-group, randomized controlled trial (RCT) investigates whether dual-task therapeutic exercises (dynamic balance + cognitive task) improve perceived stress and dynamic balance in 72 healthy university students (18-25 years) compared to traditional balance training alone or a control group receiving general health advice. The dual-task group performs the same dynamic balance exercises (e.g., backward walking, tandem gait, single-leg reaches) while simultaneously engaging in cognitive tasks (verbal fluency, arithmetic, or working memory). The intervention lasts 6 weeks (2 sessions\u002Fweek, 20-30 min each). Primary outcomes are Perceived Stress Scale (PSS-10) scores and objective dynamic balance indices (anterior\u002Fposterior\u002Flateral deviation, overall stability) measured via the Balance check 636 device. Assessments occur at baseline and post-intervention by a blinded assessor. The study addresses a gap: no prior trial has examined combined effects of dual-task training on both stress modulation and balance in this population.",[297],"Stress","2026-04-29",{"date":300,"type":33},"2026-05-06",{"date":302,"type":22},"2026-10",{"date":85,"type":22},{"name":39,"class":40},{"id":306,"slug":307,"hasResults":12,"nctId":308,"briefTitle":309,"officialTitle":310,"acronym":4,"eligibilityCriteria":311,"healthyVolunteers":12,"sex":17,"minAge":95,"maxAge":118,"enrollmentInfo":312,"targetDuration":4,"studyType":23,"phases":314,"briefSummary":315,"conditions":316,"keywords":318,"overallStatus":127,"whyStopped":4,"lastUpdateSubmitDate":324,"lastUpdatePostDateStruct":325,"startDateStruct":327,"completionDateStruct":329,"leadSponsor":330,"locationsCount":87},"100543626","phase-3-concomitant-use-of-clopidogrel-with-atorvastatin-or-rosuvastatin-in-patients-with-small-vessel-stroke-100543626","NCT06358313","Concomitant Use of Clopidogrel With Atorvastatin or Rosuvastatin in Patients With Small Vessel Stroke","Concomitant Use of Clopidogrel With Atorvastatin or Rosuvastatin in Patients With Small Vessel Stroke, a Randomized Controlled Single-blinded Trial","Inclusion Criteria:\n\n* males and females aged 18-75\n* first-ever moderate and small vessel Stroke\n* Patients are not eligible for rt-PA treatment\n\nExclusion Criteria:\n\n* The investigators excluded patients who had rapidly resolving symptoms before imaging results, and patients with a known history of persistent or recurrent CNS pathology (e.g., epilepsy, meningioma, multiple sclerosis, history of head trauma with a residual neurological deficit).\n* the investigators excluded patients who had clinical seizures at the onset of their stroke, as well as those who had symptoms of any major organ failure, active malignancies, or an acute myocardial infarction within the previous six weeks, and those who were on warfarin, regular ticagrelor during the week before admission, or chemotherapy within the previous year.\n* The investigators excluded patients with active peptic ulcers, GIT surgery, bleeding history within the last year, and those with a history of major surgery within the last three months.\n* The investigators ruled out of our trial patients who had a known allergy to the study drugs and those with INR \\> 1.4 or P.T. \\>18 or blood glucose level \\\u003C 50 or \\> 400 mg\u002FDL or blood pressure \\\u003C 90\u002F60 or \\> 185\u002F110 mmHg on admission or Platelets \\\u003C 100,000.\n* The investigators excluded pregnant and lactating patients and those with stroke due to venous thrombosis and stroke following cardiac arrest or profuse hypotension ineligible for our trial.\n* The investigators excluded patients who were regular users of drugs that affect clopidogrel metabolism, such as ketoconazole, dihydropyridine calcium channel blockers, and rifampin.",{"count":313,"type":22},600,[250],"Along with the current clinical trial, the impact of adding atorvastatin or rosuvastatin in the first 24 hours on the clinical outcomes of first-ever small vessel stroke patients treated with clopidogrel and aspirin assessed through NIHSS, mRS, and possible adverse effects.",[317],"Ischemic Stroke",[319,320,321,322,323],"atorvastatin","rosuvastatin","clopidogrel","stroke","Egypt","2026-04-20",{"date":326,"type":33},"2026-04-23",{"date":328,"type":33},"2024-04-10",{"date":79,"type":22},{"name":39,"class":40},{"id":332,"slug":333,"hasResults":12,"nctId":334,"briefTitle":335,"officialTitle":335,"acronym":4,"eligibilityCriteria":336,"healthyVolunteers":12,"sex":17,"minAge":95,"maxAge":4,"enrollmentInfo":337,"targetDuration":4,"studyType":23,"phases":339,"briefSummary":340,"conditions":341,"keywords":4,"overallStatus":127,"whyStopped":4,"lastUpdateSubmitDate":345,"lastUpdatePostDateStruct":346,"startDateStruct":348,"completionDateStruct":350,"leadSponsor":352,"locationsCount":87},"100632879","different-laser-frequencies-on-neuropathic-outcomes-in-patients-with-bells-palsy-100632879","NCT07519421","Different Laser Frequencies on Neuropathic Outcomes in Patients With Bell's Palsy","Inclusion Criteria:\n\n1. Eighty subjects from both genders diagnosed with Bell's palsy will be recruited through direct referrals from their independent physician's neurology department.\n2. Subjects aged 18 and above from all genders\n3. Unilateral Bell's palsy either on the right or left side.\n4. The Facial disability index will be used for assessment and progression of Bell's palsy before and after treatment protocol.\n5. Patients will on level II, III, IV and V of House-Brackmann scale.\n\nExclusion Criteria:\n\n1. We will exclude patients who had central nervous system pathology, sensory loss over the face, or recurrence of facial palsy.\n2. Upper motor neuron fascial nerve palsy.\n3. Any infant or child (\\\u003C18 years).\n4. Bilateral Facial nerve palsy\n5. Severe hypertension (Blood pressure more than 200\u002F120 mmHg).",{"count":338,"type":22},80,[25],"this study was done to compare different laser frequencies on neuropathic outcomes in patients with Bell's palsy.",[342,343,344],"Neuropathy, Facial","Bell Palsy","Laser","2026-04-02",{"date":347,"type":33},"2026-04-09",{"date":349,"type":33},"2025-12-01",{"date":351,"type":22},"2026-06-15",{"name":39,"class":40},{"id":354,"slug":355,"hasResults":12,"nctId":356,"briefTitle":357,"officialTitle":357,"acronym":4,"eligibilityCriteria":358,"healthyVolunteers":12,"sex":17,"minAge":359,"maxAge":360,"enrollmentInfo":361,"targetDuration":4,"studyType":23,"phases":362,"briefSummary":363,"conditions":364,"keywords":370,"overallStatus":127,"whyStopped":4,"lastUpdateSubmitDate":376,"lastUpdatePostDateStruct":377,"startDateStruct":379,"completionDateStruct":381,"leadSponsor":383,"locationsCount":87},"100587210","effect-of-task-specific-electrical-stimulation-on-upper-limb-gross-motor-skills-in-children-with-spastic-quadriplegia-100587210","NCT06925425","Effect of Task Specific Electrical Stimulation on Upper Limb Gross Motor Skills in Children With Spastic Quadriplegia","Inclusion Criteria:\n\n1. Their age will be ranged from 2 to 6 years. Their grade of spasticity will be from 1+ to 2 according to Modified Ashworth scale (Baunsgaard etal., 2016). (APPENDIX II).\n2. They will be on Level III and IV according to Gross Motor Functional Classification System (GMFCS) (Palisano et al., 2008).(APPENDIX III).\n3. Parents\u002Flegals representatives consenting to their child's participation 5 - Diagnosed with Spastic Quadriplegic cerebral palsy\n\nExclusion Criteria:\n\n1. Previous neurological or orthopedic surgery in the upperextremities.\n2. Fixed deformity in the joints of upper limb. 3- Severe hearing and visual defect.\n\n4-Irregular attendance at assessments or therapy sessions","2 Years","6 Years",{"count":270,"type":22},[25],"Cerebral palsy is a non-progressive lesion of the brain occurring before 2 years of age resulting in disorders of posture and movement.( Ostensjo S, 2004)( Keles MN, 2018). Although non- progressive, motor impairments develop as the child grows leading to activity and participation restriction.\n\nFor children with CP, body function and structure impairments include changes in muscle tone and strength that affect the ability to control movement, specifically in regard to postural responses, selective control, regulation of activity, ability to learn unique movements, and inappropriate sequencing.(Ross SA,2007)( Ostensjo S, 2004) .\n\nLack of proper loading and maladaptive muscle pulls over time causes the skeletal system to adapt to positions of malalignment, malformation, and overall bone weakness (Beckung E, 2007) (Elbasan B, 2018).\n\nThese changes lead to delays in the natural progression of gross motor skills. As the child falls behind in motor function, they also fall behind in cognitive stimulation and development.( Akaya KU, 2018) . Understanding the anatomical and physiological implications that CP has on the developing child is necessary for physical therapists to treat this population, especially when utilizing electrical stimulation.\n\nSpastic quadriplegia Is a type of cerebral palsy that affects all four limbs and typically involves significant motor impairment. It results from brain damage that occurs before, during, or shortly after birth, affecting the areas of the brain responsible for movement and coordination.\n\nElectrical stimulation is a mode of physical therapy that can be utilized in the treatment of various nerve and muscle injuries, in addition to patients with acute and chronic pain. It involves an electrical pulse applied to a muscle or nerve that activates excitable tissue utilizing internal or external electrodes to build muscle strength, reduce pain, as well as create or support limb movement (Kerr C, 2007).\n\nTask-specific electrical stimulation (TASES) is a therapeutic technique used primarily in rehabilitation settings to enhance motor function. The primary aim of TASES is to facilitate movement and improve motor learning by applying electrical stimulation to specific muscles during targeted tasks.",[365,366,367,368,369],"Cerebral Palsy (CP)","Spastic Cerebral Palsy","Quadriplegic Cerebral Palsy","Upper Limb Function","Gross Motor Delay",[371,372,373,374,375],"TASES","Cerebral palsy","Gross motor skills","Upper limb","Task specific electrical stimulation","2026-03-27",{"date":378,"type":33},"2026-04-01",{"date":380,"type":33},"2025-05-01",{"date":382,"type":22},"2026-03-29",{"name":39,"class":40},{"id":385,"slug":386,"hasResults":12,"nctId":387,"briefTitle":388,"officialTitle":389,"acronym":4,"eligibilityCriteria":390,"healthyVolunteers":186,"sex":17,"minAge":95,"maxAge":18,"enrollmentInfo":391,"targetDuration":4,"studyType":23,"phases":393,"briefSummary":394,"conditions":395,"keywords":4,"overallStatus":127,"whyStopped":4,"lastUpdateSubmitDate":396,"lastUpdatePostDateStruct":397,"startDateStruct":399,"completionDateStruct":401,"leadSponsor":403,"locationsCount":404},"100626306","l-prf-versus-sticky-bone-grafting-of-the-jumping-gap-in-ai-assisted-computer-guided-socket-shield-immediate-implantation-100626306","NCT07433920","L-PRF Versus Sticky Bone Grafting of the Jumping Gap in AI-assisted Computer-Guided Socket Shield Immediate Implantation","L-PRF Versus Sticky Bone Grafting of the Jumping Gap in AI-assisted\u002FComputer-Guided Socket Shield Immediate Dental Implantation: A Randomized Clinical Trial","Inclusion Criteria:\n\n* Medically healthy patients according to the American Society of Anesthesiologists (ASA) physical status classification system; only patients belonging to ASA I and ASA II categories will be included in this study.\n* Age \\> 18 years.\n* Patients presenting with one non-restorable hopeless anterior tooth due to extensive caries, cervical\u002Froot fracture, vertical or oblique root fracture, multiple failed endodontic treatments, or root resorption.\n* Sufficient apical\u002Fpalatal bone to obtain primary implant stability.\n\nExclusion Criteria:\n\n* Patients belonging to ASA III, ASA IV and ASA V will be excluded.\n* Vertical root fracture involving the labial aspect of the root planned to be retained as the facial shield.\n* Horizontal root fracture that is too far apically located.\n* Presence of acute (active) periapical infection.\n* Large chronic periapical lesion.\n* Lack of sufficient bone apical to the extraction socket to obtain primary stability. \\* Ankylosed tooth positioned too apically in relation to adjacent teeth.",{"count":392,"type":22},45,[25],"the rationale of the current study is to address a focused and clinically relevant gap in socket shield therapy: which biologic modality best supports healing of the shield-implant gap when SST is performed under a standardized, digitally guided workflow. The study will compare three shield-implant gap filling modalities: (i) L-PRF alone (without membrane), (ii) sticky tooth (autogenous dentin graft +i- PRF), and (iii) sticky bone (particulate graft + i- PRF) under AI-assisted, patient-specific guided implant placement based on IOS\u002FCBCT superimposition, with CBCT follow-up at immediate, 3 months, and 6 months. The working hypothesis is that biologically active, cohesive composites (sticky tooth and sticky bone) will provide superior hard- and soft-tissue dimensional stability compared with PRF alone by improving space maintenance and early wound stability in the shield-implant gap . The null hypothesis is that there will be no statistically significant differences between the three modalities in radiographic and digitally assessed clinical outcomes over the 6-month follow-up period .",[213],"2026-03-16",{"date":398,"type":33},"2026-03-18",{"date":400,"type":33},"2026-02-23",{"date":402,"type":22},"2027-03-28",{"name":39,"class":40},2,{"id":406,"slug":407,"hasResults":12,"nctId":408,"briefTitle":409,"officialTitle":410,"acronym":4,"eligibilityCriteria":411,"healthyVolunteers":186,"sex":17,"minAge":95,"maxAge":49,"enrollmentInfo":412,"targetDuration":4,"studyType":23,"phases":413,"briefSummary":414,"conditions":415,"keywords":4,"overallStatus":127,"whyStopped":4,"lastUpdateSubmitDate":418,"lastUpdatePostDateStruct":419,"startDateStruct":421,"completionDateStruct":423,"leadSponsor":425,"locationsCount":87},"100619705","guided-lateral-sinus-lifting-using-autologous-serum-albuminplatelet-rich-fibrin-100619705","NCT07348094","Guided Lateral Sinus Lifting Using Autologous Serum Albumin\u002FPlatelet-Rich Fibrin","Computer-Guided Lateral Sinus Floor Elevation Using Autologous Serum Albumin\u002FPlatelet Rich Fibrin Combined With Serum Albumin Membrane: A Randomized Clinical Study","Inclusion Criteria:\n\n* Males and females ≥18 years of age.\n\n  * ASA I and ASA II.\n  * Patients having partial edentulism in the posterior region of the maxilla.\n  * Edentulous sites consist of native non augmented bone.\n  * Horizontal ridge dimension minimum of 5mm\n  * The vertical ridge dimension 3-6 mm.\n  * Bone quality of D2 or D3.\n  * Enough inter-arch distance.\n\nExclusion Criteria:\n\n* \\- Patients with uncontrolled systemic diseases.\n* History of chronic maxillary sinus pathology.\n* Heavy smokers or patients with poor oral hygiene.",{"count":392,"type":22},[25],"This research aimed to evaluate the effect of an autologous Alb-PRF on bone regeneration after lateral sinus lifting via 3D volumetric analysis. The null hypothesis of this research was that there would be no significant difference between the group that would be treated by lateral sinus lift and Alb-PRF application and that would be treated by lateral sinus lift with bone graft for bone regeneration.",[416,417],"Sinus Perforation","Dental Implant Failure Nos","2026-02-13",{"date":420,"type":33},"2026-02-18",{"date":422,"type":33},"2026-01-26",{"date":424,"type":22},"2027-02-15",{"name":39,"class":40},{"id":427,"slug":428,"hasResults":12,"nctId":429,"briefTitle":430,"officialTitle":431,"acronym":4,"eligibilityCriteria":432,"healthyVolunteers":186,"sex":17,"minAge":95,"maxAge":49,"enrollmentInfo":433,"targetDuration":4,"studyType":23,"phases":434,"briefSummary":435,"conditions":436,"keywords":438,"overallStatus":127,"whyStopped":4,"lastUpdateSubmitDate":443,"lastUpdatePostDateStruct":444,"startDateStruct":445,"completionDateStruct":447,"leadSponsor":449,"locationsCount":87},"100612680","computer-guided-ridge-split-and-expansion-using-an-electromagnetic-mallet-100612680","NCT07256730","Computer-Guided Ridge Split and Expansion Using an Electromagnetic Mallet","Comparative Study Between Artificial Intelligence-Assisted\u002FComputer-Guided Versus Conventional Ridge Splitting Utilizing Electromagnetic Mallet for Reconstruction of Horizontal Ridge Defects: A Randomized Controlled Clinical Study","Inclusion Criteria:\n\n1. The target population with inadequate bone volume for implant placement due to width insufficiency of maxillary anterior alveolar ridges.\n2. Age ranges from 18 to 40 years of both sexes.\n3. Absence of any complicating systemic condition that may contraindicate surgical procedures and implant placement.\n4. Adequate oral hygiene.\n5. Eligible participants should present good general health and agree to random assignment to any of the two parallel study groups.\n6. Participants had a minimum 3-month post-extraction healing period and a horizontal defect in the maxillary esthetic zone with at least a bone width of 3 mm.\n\nExclusion Criteria:\n\n1. Vertical ridge defect.\n2. Undercut on the labial\u002Fbuccal side.\n3. Thick cortical bone without cancellous bone inside.\n4. Uncontrolled systematic disorders as, diabetes mellitus, uncontrolled periodontal disease, history of head and neck radiotherapy, smokers, pregnancy, noncompliant patients, allergy to the used medications, uncooperative individuals or those unable to attend the study follow-up appointments.",{"count":209,"type":22},[25],"The current trial aims to assess the efficacy of utilizing the electromagnetic mallet either by AI-assisted digital workflow or by the conventional freehand approach for reconstruction of horizontal ridge defects utilizing the ridge-split and expansion technique.",[437],"Reconstruction of Horizontal Ridge Defects",[439,440,441,442],"ridge defects","ridge split","electromagnetic mallet","dental implant","2026-02-12",{"date":418,"type":33},{"date":446,"type":33},"2024-08-27",{"date":448,"type":22},"2026-03",{"name":39,"class":40},{"id":451,"slug":452,"hasResults":12,"nctId":453,"briefTitle":454,"officialTitle":455,"acronym":4,"eligibilityCriteria":456,"healthyVolunteers":12,"sex":69,"minAge":70,"maxAge":457,"enrollmentInfo":458,"targetDuration":4,"studyType":23,"phases":459,"briefSummary":460,"conditions":461,"keywords":4,"overallStatus":127,"whyStopped":4,"lastUpdateSubmitDate":466,"lastUpdatePostDateStruct":467,"startDateStruct":469,"completionDateStruct":470,"leadSponsor":472,"locationsCount":87},"100620555","pilates-exercises-on-nonspecific-low-back-pain-in-postnatal-women-100620555","NCT07359144","Pilates Exercises on Nonspecific Low Back Pain in Postnatal Women","The Effect of Pilates Exercises on Nonspecific Low Back Pain in Postnatal Women","Inclusion Criteria:\n\n* Age ranges from 20 and 30 years old.\n* Body mass index (BMI) doesn't exceed 30 kg\u002Fm2.\n* Patients who are referred from a gynecologist with a diagnosis of nonspecific low back pain.\n* Patients who have pain for more than three months.\n* Patients who have parity ranging from one to three (to control the extreme physiological changes from multiple childbirths, ensuring a more uniform sample).\n* Patients who have score more than 4 on the Visual Analog Scale (VAS).\n\nExclusion Criteria:\n\n* Mechanical low back pain (LBP).\n* Women who had performed any spinal surgery e.g. unilateral hemilaminectomy or microdiscectomy.\n* Women with history of vertebral fracture or trauma.\n* Women with systemic disorder e.g. diabetes mellitus.\n* Women who are pregnant.\n* Women who had received physiotherapy treatment for their LBP one month before the start of this study.","30 Years",{"count":98,"type":22},[25],"This study aims to investigate the effects of Pilates for postnatal women with Non-specific low back pain (NSLBP).",[462,463,464,465],"Pilates Exercises","Nonspecific","Low Back Pain","Postnatal Women","2026-01-22",{"date":468,"type":33},"2026-01-23",{"date":466,"type":33},{"date":471,"type":22},"2026-07-01",{"name":39,"class":40},{"id":474,"slug":475,"hasResults":12,"nctId":476,"briefTitle":477,"officialTitle":478,"acronym":4,"eligibilityCriteria":479,"healthyVolunteers":12,"sex":69,"minAge":70,"maxAge":246,"enrollmentInfo":480,"targetDuration":4,"studyType":23,"phases":481,"briefSummary":482,"conditions":483,"keywords":4,"overallStatus":127,"whyStopped":4,"lastUpdateSubmitDate":487,"lastUpdatePostDateStruct":488,"startDateStruct":490,"completionDateStruct":491,"leadSponsor":492,"locationsCount":87},"100620081","transcutaneous-tibial-nerve-stimulation-on-women-with-primary-dysmenorrhea-100620081","NCT07352982","Transcutaneous Tibial Nerve Stimulation on Women With Primary Dysmenorrhea","Effect of Transcutaneous Tibial Nerve Stimulation on Women With Primary Dysmenorrhea","Inclusion Criteria:\n\n* Age ranges from 20-25 years old.\n* Body mass index (BMI) doesn't exceed 30 kg\u002Fm2.\n* Patients referred from a Gynecologist with a diagnosis of Primary Dysmenorrhea (PD).\n* Patients have regular menstrual cycles.\n* Patients suffer from pain located in the suprapubic area, abdomen, lower lumbar area, perineum, and\u002For medial aspect of the thighs during at least half of their annual menstrual cycles and\u002For in the last 3 cycles.\n\nExclusion Criteria:\n\n* Patients diagnosed with gynecological pathology.\n* Patients taking oral contraceptives or had an intrauterine device implanted.\n* Patients had bad obstetric situations or diseases that could interfere with participation.\n* Patients have certain disorders including uncorrected coagulopathies, severe comorbid disorder, cancer in the last 5 years or at present, presence of erosions on the inner aspect of the ankle, severe mental disorders, or neuropathies affecting the lower limb.\n* Patients who are smoking or taking oral sedatives.\n* Patients had undergone surgery or childbirth in the last 6 months.\n* Patients who are pregnant.",{"count":229,"type":22},[25],"This study aims to investigate the effects of transcutaneous tibial nerve stimulation (TTNS) on women with primary dysmenorrhea (PD).",[484,485,486],"Transcutaneous Tibial Nerve Stimulation","Women","Primary Dysmenorrhea","2026-01-19",{"date":489,"type":33},"2026-01-21",{"date":487,"type":33},{"date":471,"type":22},{"name":39,"class":40},{"id":494,"slug":495,"hasResults":12,"nctId":496,"briefTitle":497,"officialTitle":497,"acronym":4,"eligibilityCriteria":498,"healthyVolunteers":186,"sex":17,"minAge":246,"maxAge":19,"enrollmentInfo":499,"targetDuration":4,"studyType":23,"phases":500,"briefSummary":501,"conditions":502,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":506,"lastUpdatePostDateStruct":507,"startDateStruct":508,"completionDateStruct":510,"leadSponsor":512,"locationsCount":87},"100620699","comparison-of-laparoscopic-and-open-total-mesocolic-excision-with-central-vascular-ligation-for-right-colon-carcinoma-100620699","NCT07361016","Comparison of Laparoscopic and Open Total Mesocolic Excision With Central Vascular Ligation for Right Colon Carcinoma","Inclusion Criteria:\n\n* rt cancer colon\n\nExclusion Criteria:\n\n* metastatisis",{"count":209,"type":22},[25],"The goal of this observational comparative study is to assess whether laparoscopic complete mesocolic excision with central vascular ligation (L-CME with CVL) provides improved short-term surgical outcomes compared with open complete mesocolic excision with central vascular ligation (O-CME with CVL) in patients with right-sided colon cancer.\n\nThe primary questions this study aims to answer are:\n\nDoes laparoscopic CME with CVL reduce blood loss, postoperative complications, and length of hospital stay compared with open CME?\n\nDoes laparoscopic CME with CVL achieve equivalent surgical specimen quality and short-term oncological outcomes compared to the open approach?\n\nResearchers compared laparoscopic versus open right hemicolectomy with CME and CVL in adult patients diagnosed with right colon cancer who were eligible for elective surgical resection.\n\nParticipants underwent standard preoperative assessment, including clinical evaluation, laboratory testing, imaging studies, colonoscopy, and biopsy confirmation. Surgical treatment consisted of either laparoscopic or open complete mesocolic excision with central vascular ligation, performed according to standardized oncologic surgical principles. Postoperative care followed an enhanced recovery protocol.\n\nPrimary outcome measures included operative time, intraoperative blood loss, time to first flatus, postoperative complications, and duration of hospital stay. Secondary outcomes included quality of the surgical specimen (lymph node yield, mesocolic integrity, and margin status) and short-term oncologic outcomes, including early recurrence during follow-up.",[503,504,505],"Right-sided Colon Cancer","Colon Adenocarcinoma","Colorectal Neoplasms","2026-01-14",{"date":466,"type":33},{"date":509,"type":22},"2026-01",{"date":511,"type":22},"2027-12-31",{"name":39,"class":40},{"id":514,"slug":515,"hasResults":12,"nctId":516,"briefTitle":517,"officialTitle":517,"acronym":4,"eligibilityCriteria":518,"healthyVolunteers":12,"sex":69,"minAge":70,"maxAge":71,"enrollmentInfo":519,"targetDuration":4,"studyType":23,"phases":521,"briefSummary":522,"conditions":523,"keywords":4,"overallStatus":127,"whyStopped":4,"lastUpdateSubmitDate":526,"lastUpdatePostDateStruct":527,"startDateStruct":529,"completionDateStruct":531,"leadSponsor":532,"locationsCount":87},"100619986","effect-of-laser-acupoints-on-fallopian-tube-obstruction-100619986","NCT07351747","Effect of Laser Acupoints on Fallopian Tube Obstruction","Inclusion Criteria:\n\n* Women aged 20-35 years - nulliparous.\n* Women diagnosed with fallopian tube obstruction.\n* Body mass index less than 30 kg\u002Fm2.\n* Consent to participate in the study.\n* General good health with no major co-existing medical conditions that could interfere with the treatment or outcomes.\n* No prior fertility treatments \\[e.g., In vitro fertilization (IVF), intrauterine insemination (IUI)\\] within the last 6 months.\n* Ability to attend all scheduled sessions and follow-up assessments.\n\nExclusion Criteria:\n\n* Currently pregnant or breastfeeding.\n* History of pelvic surgery within the past year.\n* Presence of severe systemic diseases such as active cancer or severe cardiovascular diseases.\n* History of allergic reactions or adverse responses to acupuncture or laser therapies.\n* Currently undergoing hormonal therapy or use of hormonal contraceptives.\n* Current or recent history of genital tract infections, including sexually transmitted. infections, which could affect the reproductive system.\n* Presence of significant uterine anomalies diagnosed through imaging that could impact fertility.\n* Polycystic Ovary Syndrome (PCOS).",{"count":520,"type":22},36,[25],"This study aims to determine the efficacy of laser acupoint therapy on treating fallopian tube obstruction.",[344,524,525],"Acupoints","Fallopian Tube Obstruction","2026-01-10",{"date":528,"type":33},"2026-01-20",{"date":530,"type":33},"2025-04-01",{"date":378,"type":22},{"name":39,"class":40},{"id":534,"slug":535,"hasResults":12,"nctId":536,"briefTitle":537,"officialTitle":538,"acronym":539,"eligibilityCriteria":540,"healthyVolunteers":12,"sex":17,"minAge":95,"maxAge":96,"enrollmentInfo":541,"targetDuration":4,"studyType":23,"phases":542,"briefSummary":543,"conditions":544,"keywords":548,"overallStatus":127,"whyStopped":4,"lastUpdateSubmitDate":553,"lastUpdatePostDateStruct":554,"startDateStruct":556,"completionDateStruct":558,"leadSponsor":560,"locationsCount":87},"100617386","lateral-crural-steal-with-columellar-strut-graft-in-primary-open-rhinoplasty-100617386","NCT07317947","Lateral Crural Steal With Columellar Strut Graft in Primary Open Rhinoplasty","The Effect of Lateral Crural Steal With Columellar Strut Graft on Nasal Tip Projection and Rotation in Primary Open Rhinoplasty","LCS\u002FCS","Inclusion Criteria:\n\n* Patients seeking primary rhinoplasty for aesthetic and\u002For functional indications.\n* Presence of inadequate nasal tip projection and\u002For rotation suitable for correction using lateral crural steal with columellar strut graft.\n* Ability to provide written informed consent and comply with follow-up visits.\n\nExclusion Criteria:\n\n* History of prior nasal surgery.\n* History of severe nasal trauma, altering cartilage architecture.\n* Significant functional nasal obstruction requiring complex external nasal valve reconstruction.\n* Patients with excessively wide alar base requiring alar base reduction involving vestibular sill excision (to prevent confounding on projection\u002Frotation).\n* Patients with facial skeletal or developmental abnormalities e.g. maxillary hypoplasia, maxillary prognathism, dentofacial deformities.\n* Patients with psychiatric illness or Body Dysmorphic Disorder.\n* Significant medical comorbidities contraindicating elective surgery or general anesthesia.\n* Inability to provide informed consent or comply with follow-up.",{"count":209,"type":22},[25],"The goal of this clinical trial is to assess the effect of Lateral crural steal with Columellar strut graft done in Primary Open Rhinoplasty and its long-term sustainability on nasal tip projection and nasal tip rotation.",[545,546,547],"Rhinoplasty","Nasal Surgery","Aesthetic Outcomes",[545,549,550,551,552],"Lateral crural steal","Columellar strut","Rhinobase","Rhinoplasty Outcome Evaluation","2026-01-08",{"date":555,"type":33},"2026-01-09",{"date":557,"type":33},"2026-01-05",{"date":559,"type":22},"2027-02",{"name":39,"class":40},{"id":562,"slug":563,"hasResults":12,"nctId":564,"briefTitle":565,"officialTitle":565,"acronym":4,"eligibilityCriteria":566,"healthyVolunteers":12,"sex":17,"minAge":4,"maxAge":567,"enrollmentInfo":568,"targetDuration":4,"studyType":189,"phases":4,"briefSummary":570,"conditions":571,"keywords":4,"overallStatus":127,"whyStopped":4,"lastUpdateSubmitDate":575,"lastUpdatePostDateStruct":576,"startDateStruct":577,"completionDateStruct":579,"leadSponsor":581,"locationsCount":87},"100617722","diagnostic-value-of-transcranial-doppler-ultrasound-for-evaluating-neonatal-craniocerebral-injuries-100617722","NCT07322315","Diagnostic Value of Transcranial Doppler Ultrasound for Evaluating Neonatal Craniocerebral Injuries","Inclusion Criteria:\n\n* Both sexes.\n* High-risk neonates with any of the following:\n\n  * Critically ill neonates.\n  * Neonatal sepsis.\n  * Neonatal encephalopathy includes hypoxic-ischemic encephalopathy.\n  * Respiratory distress.\n  * Neonatal seizures.\n  * Birth asphyxia.\n  * Signs and or symptoms of central nervous system disorders like microcephaly, macrocephaly, hypotonia, unexplained poor feeding,\n  * Neonates born out of traumatic\u002Finstrumental labor.\n  * Suspected metabolic disturbances.\n  * Neonates with low APGAR score (\\\u003C7).\n  * Neonates with low birth weight (\\\u003C2.5 kg).\n\nExclusion Criteria:\n\n* Congenital malformations.\n* Genetic metabolic diseases or other severe complications.\n* Severe intrauterine infection.","37 Weeks",{"count":569,"type":22},60,"This study aims to evaluate the diagnostic value of transcranial Doppler ultrasonography (TCD) for evaluating neonatal craniocerebral injuries.",[572,573,574],"Diagnostic Value","Transcranial Doppler Ultrasound","Neonatal Craniocerebral Injuries","2026-01-07",{"date":553,"type":33},{"date":578,"type":33},"2026-01-06",{"date":580,"type":22},"2026-12-30",{"name":39,"class":40},""]