[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Kansas State University\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":134},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,48,77,102],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":29,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100605721","mitigating-neural-hypoexcitability-and-weakness-during-disuse-in-women-100605721",false,"NCT07166198","Mitigating Neural Hypoexcitability and Weakness During Disuse in Women","MiND","Inclusion Criteria:\n\n* Women between 40-65 years of age\n* Baseline handgrip strength \\>16Kg\n\nExclusion Criteria:\n\n* Personal or family history of blood clots\n* Current use of anticoagulant medications\n* Neuromuscular or metabolic diseases (e.g., multiple sclerosis, diabetes)\n* Arthritis\n* Osteoporosis or osteopenia\n* History of myocardial infarction within the past year\n* Chronic pain ≥3\u002F10 for ≥3 months\n* Uncontrolled hypertension (≥140\u002F90 mmHg)\n* Upper extremity surgery within the past year\n* Use of assistive hand or arm device within the past year\n* Fall involving the upper extremities within the past year\n* Upper extremity injuries preventing safe participation\n* Current use of muscle relaxants, benzodiazepines, or similar drugs\n* Smoking within the past 6 months\n* History of drug or alcohol abuse within the past year\n* Severe anxiety or claustrophobia\n* Pregnancy (current or planned)\n* Allergies to medical adhesives\n* High risk of sarcopenia (per SARC-F)\n* Contraindications to TMS or MRI\n* Upper-body resistance training within the past 6 months\n* Inability\u002Funwillingness to refrain from resistance training during study",true,"FEMALE","40 Years","65 Years",{"count":21,"type":22},20,"ESTIMATED","INTERVENTIONAL",[25],"NA","Clinical trial The goal of this clinical trial is to learn how muscle weakness and atrophy develop during short periods of arm immobilization and whether a type of exercise called cross-education can help reduce these effects in women at midlife.\n\nThe main questions it aims to answer are:\n\nWhat changes happen in the nervous system that lead to weakness when a wrist is immobilized?\n\nCan training the opposite arm help maintain muscle strength, muscle size, and nervous system function in the immobilized arm?\n\nResearchers will compare women who have their wrist immobilized with or without opposite-arm resistance training.\n\nParticipants will:\n\nWear a wrist cast on one arm for 7 days\n\nComplete strength training with the opposite arm or no training, depending on their group\n\nAttend study visits for strength and nervous system testing\n\nHave non-invasive tests (like magnetic brain stimulation, muscle recordings, and muscle imaging) to measure how the nervous system and muscle responds",[28],"Muscle Weakness",[30,31,32,33,34],"Resistance Training","Neuroplasticity","Muscle Disuse","Wrist immobilization","Women's Health","RECRUITING","2026-06-09",{"date":38,"type":39},"2026-06-10","ACTUAL",{"date":41,"type":39},"2026-05-01",{"date":43,"type":22},"2027-01-31",{"name":45,"class":46},"Kansas State University","OTHER",1,{"id":49,"slug":50,"hasResults":11,"nctId":51,"briefTitle":52,"officialTitle":53,"acronym":4,"eligibilityCriteria":54,"healthyVolunteers":11,"sex":55,"minAge":56,"maxAge":19,"enrollmentInfo":57,"targetDuration":4,"studyType":23,"phases":59,"briefSummary":60,"conditions":61,"keywords":63,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":72,"completionDateStruct":74,"leadSponsor":76,"locationsCount":47},"100622905","using-transcranial-magnetic-stimulation-to-treat-stuttering-100622905","NCT07389694","Using Transcranial Magnetic Stimulation to Treat Stuttering","Modulating Bilateral Cortical Activation In Adults Who Stutter: A Pilot Study","Inclusion Criteria:\n\n* Age from 18 to 65 years\n* Self-identifies as a person who currently stutters\n* Right-handed or left-handed\n* Normal hearing and (corrected) vision\n* Able to understand and give informed consent\n* Monolingual English speaker\n\nExclusion Criteria:\n\n* Cardiac pacemaker or pacemaker wires; neurostimulators; implanted pumps\n* Metal in the body (rods, plates, screws, shrapnel, dentures, IUD) or metallic particles in the eye\n* Facial tattoos\n* Not having medical insurance\n* Surgical clips in the head or previous neurosurgery\n* Any magnetic particles in the body\n* Cochlear implants\n* Prosthetic heart valves\n* Epilepsy or any other type of seizure history\n* History of significant head trauma (i.e., extended loss of consciousness, neurological sequelae)\n* Known structural brain lesions\n* Pre-existing speech, language, or neurological disorder (except for stuttering)\n* Significant other disease (heart disease, malignant tumors, mental disorders)\n* Significant claustrophobia; Ménière's disease\n* Women who are trying to get pregnant and sexually active women (of reproductive age) not on a reliable contraceptive\n* Pregnancy, breastfeeding\n* Medications increasing the risk for seizures\n* Non-prescribed drug use\n* Use of recreational drugs such as medical marijuana\n* Failure to perform the behavioral tasks or neuropsychological evaluation tests\n* Prisoners","ALL","18 Years",{"count":58,"type":22},2,[25],"The goal of this clinical trial is to learn if repeated transcranial magnetic stimuli (rTMS) can treat stuttering in adults. The main questions it aims to answer are:\n\n* Will there be changes in the brains of people who stutter because of the treatment?\n* Will any changes in the brain result in less stuttering?\n\nParticipants will:\n\n* Visit the lab 3 times before treatment for tests\n* Complete 10 rTMS sessions\n* Visit the lab 2 times after treatment for tests",[62],"Stuttering, Adult",[64,65,66,67,68],"stuttering","noninvasive treatment","transcranial magnetic stimulation","eye tracking","EEG","2026-02-04",{"date":71,"type":39},"2026-02-06",{"date":73,"type":22},"2026-02-15",{"date":75,"type":22},"2027-12-15",{"name":45,"class":46},{"id":78,"slug":79,"hasResults":11,"nctId":80,"briefTitle":81,"officialTitle":82,"acronym":4,"eligibilityCriteria":83,"healthyVolunteers":16,"sex":55,"minAge":84,"maxAge":85,"enrollmentInfo":86,"targetDuration":4,"studyType":23,"phases":88,"briefSummary":89,"conditions":90,"keywords":92,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":94,"lastUpdatePostDateStruct":95,"startDateStruct":97,"completionDateStruct":99,"leadSponsor":101,"locationsCount":47},"100607965","data-coaching-process-to-address-staff-physical-activity-promoting-behavior-and-child-physical-activity-100607965","NCT07195409","Data Coaching Process to Address Staff Physical Activity Promoting Behavior and Child Physical Activity","Examining the Effectiveness of a Data Coaching Process to Increase Child Physical Activity, Perceived Motor Competence, and Staff Physical Activity Promoting Practices: A Randomized Controlled Trial","Inclusion Criteria:\n\n* All student enrolled in the after-school programs at the elementary level\n\nExclusion Criteria:\n\n* Not enrolled in the after-school program and not at the elementary level.","5 Years","11 Years",{"count":87,"type":22},80,[25],"The goal of this study is to determine whether a data coaching process called Out of School Time Coach (OST-Coach) can increase child physical activity (PA) behavior, perceived motor competence, and staff PA-promoting practices.\n\nAim 1: Determine the impact that the OST-Coach intervention has on child PA behavior and perceived motor competence. The investigators hypothesize that integrating a targeted data coaching system will increase the amount of PA children engage in during the OST program and enhance their perceived motor competence compared to sites receiving standard practice.\n\nAim 2: Assess the impact of the OST-Coach intervention on staff PA-promoting practices. The investigators will measure the effectiveness of the OST-Coach intervention by observing staff behavior and assessing their willingness to integrate evidence-based practices during OST programming. It is hypothesized that OST leaders at intervention sites will implement more PA-promoting practices.\n\nChild physical activity will be measured via systematic observation and a survey assessing perceived motor competence. Staff PA-promoting behaviors will be observed via systematic observation and evaluated through a survey to understand the impact of the data coaching process. The intervention is delivered at the staff level, with feedback provided four times throughout the academic year.",[91],"Physical Activity",[93],"physical activity; staff behavior; motor competence","2025-09-19",{"date":96,"type":39},"2025-09-26",{"date":98,"type":39},"2025-09-10",{"date":100,"type":22},"2026-07-01",{"name":45,"class":46},{"id":103,"slug":104,"hasResults":11,"nctId":105,"briefTitle":106,"officialTitle":107,"acronym":4,"eligibilityCriteria":108,"healthyVolunteers":11,"sex":55,"minAge":56,"maxAge":19,"enrollmentInfo":109,"targetDuration":4,"studyType":23,"phases":111,"briefSummary":113,"conditions":114,"keywords":119,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":126,"lastUpdatePostDateStruct":127,"startDateStruct":129,"completionDateStruct":131,"leadSponsor":133,"locationsCount":47},"100582044","phase-2-promoting-active-therapy-path-to-wellness-100582044","NCT06858189","Promoting Active Therapy: Path to Wellness","Can Nature-based Physical Activity Improve Symptoms of Depression and Anxiety?","Inclusion Criteria:\n\n* Current client of a participating therapist who has completed study training\n* Diagnosed depressive or anxiety disorder\n* Able to safely engage in moderate physical activity\n* Willing to complete all study requirements\n\nExclusion Criteria:\n\n* Planning to discontinue therapy in less than 6 months\n* Active suicidal ideation\n* Does not pass exercise risk screener",{"count":110,"type":22},60,[112],"PHASE2","This project will examine changes in depression and anxiety following a 10-week intervention promoting nature-based physical activity in mental health settings. We will recruit ten licensed therapists whose caseload includes adults with depression and anxiety. Following a training by our team, each participating therapist will recruit six clients, who will be randomly assigned to the intervention or control condition. Clients in the intervention condition will engage in walk-and-talk therapy outdoors during weekly sessions and discuss strategies for being active outdoors on their own. We will assess changes in depression, anxiety, and nature-based physical activity in both groups.",[115,91,116,117,118],"Depression, Anxiety","Time in Nature","Self-Efficacy","Feasibility Pilot Study",[120,121,122,123,124,125],"therapy","nature prescriptions","park prescriptions (ParkRx)","exercise","mental health","walk-and-talk","2025-02-27",{"date":128,"type":39},"2025-03-05",{"date":130,"type":39},"2025-02-28",{"date":132,"type":22},"2026-05-31",{"name":45,"class":46},""]