[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Katherine Mathews\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":64},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":4,"maxAge":4,"enrollmentInfo":16,"targetDuration":4,"studyType":19,"phases":4,"briefSummary":20,"conditions":21,"keywords":23,"overallStatus":52,"whyStopped":4,"lastUpdateSubmitDate":53,"lastUpdatePostDateStruct":54,"startDateStruct":57,"completionDateStruct":59,"leadSponsor":61,"locationsCount":5},"100081216","clinical-trial-readiness-for-the-dystroglycanopathies-100081216",false,"NCT00313677","Clinical Trial Readiness for the Dystroglycanopathies","Inclusion Criteria:\n\n* Elevated CK (creatine kinase)\n* Evidence of a dystroglycanopathy as determined by review of muscle pathology OR documented mutation in one of the known genes OR abnormal alpha-dystroglycan glycosylation in cultured fibroblasts\n* Dystroglycanopathies are predicted to affect all racial and ethnic backgrounds, and all patients with dystroglycanopathies will be eligible for participation.\n* Participants may be of any age, including children, and males and females will be recruited equally.\n* Patients will have varying degrees of muscular weakness, but otherwise should be in relatively good health.\n\nExclusion Criteria:\n\n* There are no exclusion criteria.","ALL",{"count":17,"type":18},190,"ESTIMATED","OBSERVATIONAL","The purpose of the study is to describe the early signs and symptoms of the dystroglycanopathies, and to gather information that will be required for future clinical trials.",[22],"Muscular Dystrophy",[24,25,26,27,28,29,30,31,32,33,34,35,36,37,38,39,40,41,42,43,44,45,46,47,48,49,50,51],"muscular dystrophy","MD","fukutin-related protein gene","limb girdle","FKRP gene","congenital muscular dystrophy","childhood onset LGMD","adult onset LGMD","POMT1","POMT2","POMGnT1","LARGE","alpha dystroglycan","dystroglycanopathy","ISPD\u002FCRPPA","DPM 1, 2 or 3","GMPPB","B3GNT1\u002FB4GAT1","B3GALNT2","GTDC2\u002FPOMGnT2","TMEM5\u002FRXYLT1","Fukutin","DAG1","POMK\u002FSGK196","DOLK","TRAPPC11","GOSR2","INPP5K","RECRUITING","2025-07-24",{"date":55,"type":56},"2025-07-30","ACTUAL",{"date":58,"type":4},"2006-04",{"date":60,"type":18},"2030-07",{"name":62,"class":63},"Katherine Mathews","OTHER",""]