[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Keck School of Medicine of USC\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":82},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,53],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":15,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":33,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":41,"lastUpdatePostDateStruct":42,"startDateStruct":45,"completionDateStruct":47,"leadSponsor":49,"locationsCount":52},"100609844","evaluating-a-clinical-decision-support-tool-for-antiretroviral-therapy-optimization-100609844",false,"NCT07219862","Evaluating a Clinical Decision Support Tool for Antiretroviral Therapy Optimization","Inclusion Criteria:\n\nHIV patients\n\n1. Documented HIV-1 infection\n2. Greater than 18 years of age\n3. Genotype resistance testing previously conducted or scheduled through clinical care\n\nProviders:\n\nHIV care providers who will determine treatment selections, with or without utilizing our clinical decision support tool\n\nExclusion Criteria:\n\nHIV patients:\n\n1\\. Refusal or inability to give informed consent\n\nProviders:\n\n1\\. Refusal to give informed consent",true,"ALL","18 Years",{"count":19,"type":20},250,"ESTIMATED","INTERVENTIONAL",[23],"NA","This study is testing software designed to help healthcare providers choose the best HIV treatment combinations for their patients. HIV medicines, known as antiretroviral therapy (ART), can be complex to manage because the right regimen depends on many factors-such as drug resistance, other health conditions, and medication schedules. Many people with HIV are cared for by general clinicians who may not have access to HIV specialists, which can make treatment decisions more challenging.\n\nIn this study, healthcare providers will use patient cases to compare standard HIV treatment resources with a new clinical decision support tool that gives evidence-based ART recommendations at the point of care.\n\nThe investigators hypothesize that using the tool will help providers select treatment plans that better match clinical guidelines, make decisions faster, reduce mental effort, and increase overall satisfaction with the prescribing process.",[26,27,28,29,30,31,32],"HIV (Human Immunodeficiency Virus)","Clinical Decision Support System (CDSS)","Antiretroviral Therapy, Highly Active","INDIVIDUALIZED THERAPY","AIDS (Acquired Immune Deficiency Syndrome)","Personalized Medicine","Precision Medicine",[34,35,36,37,38,39],"hiv","clinical decision support system","antiretroviral therapy","aids","personalized medicine","precision medicine","NOT_YET_RECRUITING","2025-10-20",{"date":43,"type":44},"2025-10-22","ACTUAL",{"date":46,"type":20},"2028-09-01",{"date":48,"type":20},"2031-09-01",{"name":50,"class":51},"Keck School of Medicine of USC","OTHER",1,{"id":54,"slug":55,"hasResults":11,"nctId":56,"briefTitle":57,"officialTitle":58,"acronym":4,"eligibilityCriteria":59,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":60,"targetDuration":4,"studyType":21,"phases":62,"briefSummary":64,"conditions":65,"keywords":68,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":74,"lastUpdatePostDateStruct":75,"startDateStruct":77,"completionDateStruct":79,"leadSponsor":81,"locationsCount":52},"100543080","phase-3-po-methadone-ortho-outpatient-100543080","NCT06351215","PO Methadone Ortho Outpatient","Use of Single-Dose Oral Methadone for Pain Management in Outpatient Arthroscopic Hip and Knee Procedures","Inclusion Criteria:\n\n* medically optimized participants who will undergo elective arthroscopic knee or hip repair\n\nExclusion Criteria:\n\n* pregnant or breastfeeding, age under 18, history of respiratory compromise, allergy to opioids, recipient of pre-operative nerve block",{"count":61,"type":20},100,[63],"PHASE3","The goal of this clinical trial is to learn if oral methadone given before surgery works to minimize post-operative pain and opioid usage. The main questions it aims to answer are:\n\nDoes oral methadone improve post-operative pain scores as compared to standard treatment? Does oral methadone lead to reduced use of post-operative and post-discharge opioid usage as compared to the current standard treatment?\n\nResearchers will compare oral methadone to a placebo (a look-alike substance that contains no drug) to assess the questions above.\n\nParticipants will:\n\nReceive either oral methadone or a look-alike placebo before surgery Receive standard intraoperative and immediate post-operative pain control at the anesthesiologist's discretion Be asked about their pain levels in the recovery area Keep a diary of pain and opioid usage over the first 2 days after surgery",[66,67],"Arthroscopic Knee Repair","Arthroscopic Hip Repair",[69,70,71,72,73],"arthroscopic knee repair","arthroscopic hip repair","oral methadone","post-operative pain control","ambulatory surgery","2025-03-03",{"date":76,"type":44},"2025-03-05",{"date":78,"type":20},"2025-05-01",{"date":80,"type":20},"2025-12-15",{"name":50,"class":51},""]