[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Keele University\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":126},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,42,68,99],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":26,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":32,"startDateStruct":35,"completionDateStruct":37,"leadSponsor":39,"locationsCount":4},"100583101","can-wearable-technology-be-used-to-predict-exercise-intensity-100583101",false,"NCT06871943","Can Wearable Technology be Used to Predict Exercise Intensity","Developing a Rationale for the Use of Breathing Frequency and Wearable Foot-pods to Measure Intensity in Cardiac Populations","(CWTPEI)","Inclusion Criteria:\n\n* Myocardial Infraction in the past 6 months\n* Able to walk on a treadmill\n* Aged ≥ 18\n\nExclusion Criteria:\n\n• Injury or condition that impedes normal gait","ALL","18 Years",{"count":20,"type":21},24,"ESTIMATED","OBSERVATIONAL","There is a knowledge gap in the literature around using watts to measure exercise intensity in walking and running, this is largely due to new technological developments. Whereas the relationship is widely recognised and used for cycling in elite to clinical populations.\n\nWhile the relationship breathing rate and exercise intensity is well established, this are no guidelines using breathing rate as a physiological measure of intensity. New technology may aid to bridge these gaps.\n\nThe main aims of the study are: -\n\nCan the relationship between oxygen uptake and watts during incremental exercise Can breathing frequency be used to determine aerobic exercise intensity\n\nThe participants will complete two 9 minute incremental accredited exercise tests on the flat around cones and on treadmill at the given speed of walking around the cones. The test will stop at 6.8kph or at participant volition.",[25],"Myocardial Infarction (MI)",[27,28,29],"aerobic capacity","breathing frequency","walking capacity","NOT_YET_RECRUITING","2026-06-09",{"date":33,"type":34},"2026-06-10","ACTUAL",{"date":36,"type":21},"2026-10-01",{"date":38,"type":21},"2027-06-30",{"name":40,"class":41},"Keele University","OTHER",{"id":43,"slug":44,"hasResults":11,"nctId":45,"briefTitle":46,"officialTitle":47,"acronym":4,"eligibilityCriteria":48,"healthyVolunteers":49,"sex":17,"minAge":4,"maxAge":4,"enrollmentInfo":50,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":52,"conditions":53,"keywords":55,"overallStatus":59,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":60,"startDateStruct":62,"completionDateStruct":64,"leadSponsor":66,"locationsCount":67},"100528988","developing-allogeneic-musculoskeletal-therapies-100528988","NCT06167928","Developing Allogeneic Musculoskeletal Therapies","Investigating the Potential for Musculoskeletal Tissues and Cells Isolated From Juvenile Patients in the Development of Novel Therapies for Cartilage and Bone Injury and Osteoarthritis","Inclusion Criteria:\n\nFor juvenile\u002Finfant donors:\n\n* Parents\u002Fguardians being able to provide signed and dated informed consent form.\n* Scheduled for one of the following surgical treatments:\n\nDigit amputations due to polydactyly. Surgery to treat dislocated hips.\n\nFor biobank\u002FNHSBT donors\n\n* Informed consent via consenting institution.\n\nExclusion Criteria:\n\n* Parents\u002Fguardians not understanding the Patient Information Sheet",true,{"count":51,"type":21},325,"The goal of this observational study is to analyse the cartilage and bone forming potential of cells isolated from the tissues of patients undergoing surgery for the treatment of polydactyly, hip dislocation and from other bio-banked cartilage tissues. The main question it aims to answer is:\n\nWhich of the following tissues from polydactyly digit, iliac apophysis or other bio-banked cartilage produce better cartilage in vitro and in vivo? Participants receiving digit amputation surgery for treatment of polydactyly will be asked to donate the associated waste tissue whilst participants receiving surgery to treat a dislocated hip will be asked to donate an extra small piece of cartilage tissue (approximately 1 gram) from the iliac apophysis. Other tissues for the study will be obtained from those donated to biobanks.",[54],"Osteoarthritis",[56,57,58],"Cell therapy","Musculoskeletal","Allogeneic","RECRUITING",{"date":61,"type":34},"2026-06-11",{"date":63,"type":34},"2018-10-08",{"date":65,"type":21},"2037-09-01",{"name":40,"class":41},1,{"id":69,"slug":70,"hasResults":11,"nctId":71,"briefTitle":72,"officialTitle":73,"acronym":74,"eligibilityCriteria":75,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":76,"targetDuration":4,"studyType":78,"phases":79,"briefSummary":81,"conditions":82,"keywords":85,"overallStatus":59,"whyStopped":4,"lastUpdateSubmitDate":91,"lastUpdatePostDateStruct":92,"startDateStruct":94,"completionDateStruct":96,"leadSponsor":98,"locationsCount":67},"100640708","somatosensory-stimulation-for-unilateral-neglect-post-stroke-ssun-100640708","NCT07589855","Somatosensory Stimulation for Unilateral Neglect Post Stroke (SSUN)","Mobilization and Tactile Stimulation (MTS) to Improve Unilateral Neglect Post Stroke: a Pilot and Feasibility Study","SSUN","Inclusion Criteria:\n\n* Adult (≥18 years of age) who is an Adult stroke survivors (≥18 years of age) with a clinical diagnosis of UN, in the subacute-chronic phase of stroke (≥20 weeks post stroke)\n* Ability to consent to participate in the study, assessed by their understanding of the study when it is explained to them.\n* Sufficient cognitive and physical ability to allow inclusion in this study, assessed by the ability to follow a simple one-stage command with the non-paretic limb.\n* Able and willing to receive and engage with regular therapy (MTS) (e.g. at home).\n\nExclusion Criteria:\n\n* Stroke survivor with major communication problems (e.g receptive aphasia) that affect their understanding of the treatment, their ability to follow instruction, or ability to consent to participate.\n* Participants who do not speak\u002Funderstand English and who do not have access to an interpreter.",{"count":77,"type":21},6,"INTERVENTIONAL",[80],"NA","The Intervention, called Mobilization and tactile Stimulation (MTS for short) is a hands-on physical therapy technique that can be used to treat the arm and hand after a stroke. It includes joint movements, massage, and sensory input like touch and compression. MTS is part of routine therapy for stroke patients when people cannot move or feel their arm normally. It may help with problems like neglect, which is when people are not aware of one side of their body after their stroke. The effectiveness of MTS to help people with neglect has not been widely studied yet.\n\nthe investigators plan to invite adult stroke patients (18 years and over) with signs of neglect, who are more than 20 weeks post-stroke to be part of this study. They must be willing to have regular therapy at home, and each participant will need to have a carer who can assist with the research.\n\nParticipants will be in the study for approximately three months. In the first two weeks they will not receive the MTS treatment but will have some regular measures undertaken (see details below). This is called the baseline Phase A stage.\n\nThen they move to Phase B where the investigators will deliver MTS therapy for 45-60 minutes, five days a week for six weeks. This is the treatment phase, known as Phase B. The regular measures will also continue during Phase B.\n\nOnce the six weeks of MTS treatment is completed there is a final stage for two weeks (also known as Phase A because there is no treatment delivered). This is the withdrawal phase. The regular measures will continue during this phase.\n\nTo see if the MTS has any impact on the stroke survivors the investigators will take regular measurements. The investigators will be using three different assessments for neglect.\n\n* The Letter Cancellation Test. The investigators will ask participants to cross out target letters from a sheet with various letters on it.\n* The Catherine Bergego Scale (CBS). This is a 10-item checklist where a therapist or carer observes daily activities and scores the stroke survivor doing everyday activities e.g., brushing your hair and eating.\n* The Fluff Test. In this test participants will be blindfolded and then asked to remove stickers from their body using their non-affected hand.\n\nDuring the study, participants will be assessed by a research therapist twice a week using the three tests. Carers will be trained to use the CBS and will also conduct daily assessments.\n\nAfter the 10 weeks is completed, the participant will be invited to share your experiences with us in an interview. This will help us understand better whether anything has changed because of being in this study.\n\nMTS is commonly used in clinical practice and has a low risk of side effects. There is a small risk of overuse syndrome, which can cause arm discomfort, but this can be managed by adjusting the therapy. While the investigators cannot guarantee direct benefits to participants, clinicians that investigators spoke to told us they thought the extra treatment could be beneficial for stroke survivors.",[83,84],"Stroke","Unilateral Neglect Syndrome",[83,86,87,88,89,90],"Unilateral neglect","inattention","somatosensory stimulation","sensory stimulation","Mobilization and Tactile Stimulation","2026-05-13",{"date":93,"type":34},"2026-05-15",{"date":95,"type":34},"2025-10-20",{"date":97,"type":21},"2026-07-01",{"name":40,"class":41},{"id":100,"slug":101,"hasResults":11,"nctId":102,"briefTitle":103,"officialTitle":104,"acronym":4,"eligibilityCriteria":105,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":106,"targetDuration":108,"studyType":22,"phases":4,"briefSummary":109,"conditions":110,"keywords":112,"overallStatus":59,"whyStopped":4,"lastUpdateSubmitDate":118,"lastUpdatePostDateStruct":119,"startDateStruct":121,"completionDateStruct":123,"leadSponsor":125,"locationsCount":67},"100504025","the-national-musculoskeletal-audit-and-research-database-100504025","NCT05842915","The National Musculoskeletal Audit and Research Database","Developing and Testing a Musculoskeletal National Audit in Community\u002FPrimary Care","Inclusion Criteria:\n\n(MSK Services)\n\n* MSK service seeing adult (+18 years) set in community care\n* MSK service with at least 10 WTE HCPs\n* System in place for digital collection of PROM\u002FPREM data\n\n(FCP Services)\n\n* FCP service seeing adult (+18 years) in primary care\n* FCP service with at least 1 WTE FCP seeing MSK patients\n* Use of EMIS or SYSTMONE\n* Able to implement Midlands FCP template\n* System in place for digital collection of PROM\u002FPREM data\n\n(For patients)\n\n* +18 years\n* Active phone number or verified email address to participate in the patient questionnaire\n* Able to provide informed consent\n\nExclusion Criteria:\n\n(MSK Services)\n\n\\* Secondary care MSK services\n\n(For patients)\n\n* Has declined for data to be part of research as part of consent process\n* Unable to complete surveys due to health issues including severe or terminal illness, severe learning difficulties or psychological disorders",{"count":107,"type":21},22000,"12 Months","Developing and testing a musculoskeletal national audit in community\u002Fprimary care",[111],"Musculoskeletal Diseases",[113,114,115,116,117],"Primary Care","Community","Benchmarking","Audit","Quality Improvement","2026-02-04",{"date":120,"type":34},"2026-02-05",{"date":122,"type":34},"2024-05-07",{"date":124,"type":21},"2028-06-07",{"name":40,"class":41},""]