[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Kepler University Hospital\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":95},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,42,74],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":4,"maxAge":4,"enrollmentInfo":17,"targetDuration":4,"studyType":20,"phases":4,"briefSummary":21,"conditions":22,"keywords":25,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":41},"100631847","anastomotic-bleeding-in-colorectal-anastomosis-relating-to-the-placement-of-the-stapler-spike-to-the-staple-line-100631847",false,"NCT07506005","Anastomotic Bleeding in Colorectal Anastomosis Relating to the Placement of the Stapler Spike to the Staple Line","Anastomotic Bleeding in Primary Double-stapled Colorectal Anastomosis Relating to the Placement of the Stapler Spike to the Staple Line","Inclusion Criteria:\n\n* Age ≥ 18 years\n* Colorectal surgery with primary colorectal anastomosis using the double-stapling technique, including side-to-end or end-to-end anastomosis\n* Documented anastomotic orientation (mesenteric vs. antimesenteric)\n\nExclusion Criteria:\n\n* TME","ALL",{"count":18,"type":19},102,"ESTIMATED","OBSERVATIONAL","Each colorectal anastomosis is routinely evaluated intraoperatively by sigmoidoscopy and, in the presence of signs of bleeding, also postoperatively (persistent rectal bleeding within 24 hours after surgery).",[23,24],"Colorectal Cancer","Diverticulitis",[26,27,28],"Colorectal anastomosis","Double Stapling","Anastomotic Bleeding","RECRUITING","2026-03-29",{"date":32,"type":33},"2026-04-01","ACTUAL",{"date":35,"type":33},"2024-12-18",{"date":37,"type":19},"2028-12-31",{"name":39,"class":40},"Kepler University Hospital","OTHER",1,{"id":43,"slug":44,"hasResults":11,"nctId":45,"briefTitle":46,"officialTitle":47,"acronym":48,"eligibilityCriteria":49,"healthyVolunteers":11,"sex":16,"minAge":50,"maxAge":4,"enrollmentInfo":51,"targetDuration":4,"studyType":53,"phases":54,"briefSummary":56,"conditions":57,"keywords":59,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":73},"100511699","quality-of-life-in-acute-complicated-and-chronic-recurrent-left-sided-diverticulitis-100511699","NCT05942833","Quality of Life in Acute Complicated and Chronic Recurrent Left-sided Diverticulitis","DATE Trial: Outcomes and Quality of Life in Patients With Early Versus Elective Resection in Acute Complicated and Chronic Recurrent Left-sided Diverticulitis","DATE","Inclusion Criteria:\n\n* Informed consent to participate in the study\n* CDD Type 2a, 2b: acute complicated left-sided diverticulitis\n* CDD Type 3b: relapsing diverticulitis without complications (\\>2 episodes within 2 years)\n* Acute presentation\n* Inflammation located in the left-sided colon\n* Inflammation is CT proven or ultrasound confirmed from experienced radiologists\n\nExclusion Criteria:\n\n* \\\u003C 18 years\n* Pregnancy\n* BMI \\> 55kg\u002Fm2\n* Current colorectal carcinoma in the left-sided colon\n* Oral and\u002For intravenous corticosteroid\n* Ongoing chemotherapy\n* Status post left hemicolectomy\n* Patients who cannot take care of themselves at home or are unable to follow instructions\n* Patients who are not fit for surgery (anesthesia, expert knowledge from specialists) and will not benefit from surgery","18 Years",{"count":52,"type":19},136,"INTERVENTIONAL",[55],"NA","Patients presenting in hospital with symptoms of acute diverticulitis. Acute inflammation of the left-sided colon is confirmed with CT scan or ultrasound in experienced centers and diagnosis is defined according to the \"Classification of Diverticular Disease (CDD)\". CDD Type 2a, 2b and 3b will be included and then randomized in two groups. Group A will get an early left hemicolectomy 7 to 10 days after admission and initial antibiotic therapy and\u002For drainage of the abscess. Group B is designated for an elective resection 6 to 8 weeks after dismissal at the earliest and initial conservative treatment and\u002For after drainage of the abscess. Six weeks after the operation patients of Group A will be asked for their present quality of life with a standardized scoring system (Gastrointestinal Quality of Life Index = GIQLI; Short-form 36 Score = SF-36 Score; Low anterior resection syndrome = LARS Score). Group B (elective resection) will be asked at their readmission prior to elective surgery is done. This survey package will be repeated again 6 to 8 weeks later in both groups. Primary endpoints will be the two GIQLI at the said examination times. Secondary endpoints will be SF-36 score, LARS-score, GIQLI-Domains, anastomosis insufficiency and other complications, mortality and length of hospital stay. Comparisons between the groups are made at the said examination times but also 6-8 weeks after the operation.",[58],"Diverticulitis of Sigmoid",[60,61,62,63,64],"Recurrent diverticulitis","Quality of life","Acute complicated Diverticulitis","Early resection","Elective resection","2026-03-16",{"date":67,"type":33},"2026-03-18",{"date":69,"type":33},"2023-01-16",{"date":71,"type":19},"2027-07",{"name":39,"class":40},4,{"id":75,"slug":76,"hasResults":11,"nctId":77,"briefTitle":78,"officialTitle":78,"acronym":79,"eligibilityCriteria":80,"healthyVolunteers":11,"sex":16,"minAge":50,"maxAge":4,"enrollmentInfo":81,"targetDuration":4,"studyType":20,"phases":4,"briefSummary":83,"conditions":84,"keywords":4,"overallStatus":86,"whyStopped":4,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":90,"completionDateStruct":92,"leadSponsor":94,"locationsCount":41},"100518472","prediction-of-outcome-in-out-of-hospital-cardiac-arrest-100518472","NCT06030986","Prediction of Outcome in Out-of-Hospital Cardiac Arrest","PREDOHCA","Inclusion Criteria:\n\n* Patients 18 years or older AND\n* between 2015-01-01 and 2023-10-31 AND\n* have been treated by emergency medical teams of the Austrian Red Cross, District Branch of Upper Austria AND\n* have suffered out-of-hospital cardiac arrest AND\n* have been treated by emergency physicians while out of hospital AND\n* have been transported to the Kepler University Hospital, Linz, Austria\n\nExclusion Criteria:\n\n\\- none",{"count":82,"type":19},10000,"In the course of prehospital respiratory and circulatory arrest, approximately 1000 persons are resuscitated by cardiopulmonary resuscitation in Upper Austria every year. Despite constant further development of methods, equipment and continuous training of the rescue and emergency medical teams working on site, the majority of patients who have to be resuscitated prehospital still die. However, even patients whose circulatory function can be restored during prehospital resuscitation (Return of Spontaneous Circulation, ROSC) require intensive medical care for days to weeks and often find it very difficult to return to a normal, independent life.\n\nThe success of resuscitation measures depends on the quality of the resuscitation performed as well as on patient-specific factors. Evaluation scales such as the Cerebral Performance Category score (CPC) allow a posteriori assessment of resuscitation success. Nowadays, it is very difficult to estimate the outcome of resuscitation a priori. In many cases, it is not at all clear at the beginning of the treatment pathway whether the individual patient is expected to have an unfavorable prognosis in the context of respiratory arrest or whether a restitutio ad integrum is possible.\n\nThus, the decision to continue or discontinue resuscitation can only be made on the basis of an individual physician's assessment. In addition to the primary concern of stopping resuscitation too early, there is also the risk that medical resources are used beyond the normal level after resuscitation without expecting a successful outcome. Estimating and categorizing the subsequent outcome is difficult and emotionally stressful for the treating team in the acute situation. Some factors that influence outcome are now known: As cerebral hypoperfusion increases, the probability of survival decreases sharply with each passing minute. In this context, potentially reversible causes have been identified in different works, allowing causal therapy to improve neurological outcome. In addition to the most important therapy bridging hypoperfusion, chest compression, with the aim of ensuring minimal perfusion of the brain, immediate defibrillation should be mentioned in particular, which now allows medical laypersons to use defibrillators as part of the Public Access Defibrillation Network.\n\nDespite all efforts, however, it is not yet possible to make reliable statements about the probable outcome of persons with respiratory and circulatory arrest with a high degree of certainty in a large number of cases at an early stage.\n\nArtificial intelligence refers to the ability of machines to perform cognitive tasks, such as recognizing objects in images and classifying them. For a long time, many processes were too complex to explore through sufficient computing power, storage capacity, and understanding. More recently, however, technological advances have brought machine learning (ML) and the constructs behind it, including those based on so-called neural networks (known since about 1950), back to the fore. Not only the development of theoretical models, but after extensive testing also devices applicable in daily routine operation are available.\n\nModern machine learning methods are enabling a variety of new approaches to assessing operations, including modeling complex systems and finding relationships between models.",[85],"Cardiac Arrest","NOT_YET_RECRUITING","2025-06-30",{"date":89,"type":33},"2025-07-03",{"date":91,"type":19},"2025-12-01",{"date":93,"type":19},"2026-12-31",{"name":39,"class":40},""]