[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"King Abdulaziz Medical City\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":46},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":29,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":5},"100575242","phase-4-the-prolonging-effect-of-dexmedetomidine-on-spinal-anesthesia-through-different-routes-if-administrations-100575242",false,"NCT06769737","The Prolonging Effect of Dexmedetomidine on Spinal Anesthesia Through Different Routes if Administrations","The Prolonged Effects of Spinal Dexmedetomidine Versus Intravenous Dexmedetomidine on Spinal Anesthesia With Isobaric Bupivacaine: A Comparative Study","Inclusion Criteria:\n\n* Male and female patients in adult age group more than 18 years old\n* ASA classification I, II, and III.\n* Orthopedic surgery, including total hip replacement (THR) and total knee replacement (TKR).\n* No history of Obstructive sleep apnea\n\nExclusion Criteria:\n\n* Patient below 18 years old of both genders.\n* ASA classification of IV and more.\n* Patients with a height of less than 150 cm.\n* Patients on alpha-two antagonist ACE inhibitors and CCB.\n* Patient received intrathecal morphine, intravascular dexamethasone, or Midazolam\n* Patient who can't tolerate fluid challenge. Example: ESRD, HF…etc.\n* Any contraindication for neuraxial procedure. Examples: coagulopathy, severe AS, sepsis…etc.\n* Psychiatric patients.",true,"ALL","18 Years","80 Years",{"count":21,"type":22},75,"ESTIMATED","INTERVENTIONAL",[25],"PHASE4","This prospective, double-blinded, randomized clinical trial aims to examine the effects of combining isobaric bupivacaine with dexmedetomidine administered intrathecally (IT), compared to the combination of isobaric bupivacaine administered intrathecally and dexmedetomidine administered intravenously (IV), on spinal anesthesia prolongation time in minutes, time of regression from Bromage score 3 to 0.",[28],"Spinal Anesthesia Evaluation",[30,31,32,33],"dexmedetomedine","intrathecal dexmedetomedine","intravenous dexmedetomedine","spinal anesthesia prolongation","NOT_YET_RECRUITING","2025-01-07",{"date":37,"type":38},"2025-01-10","ACTUAL",{"date":40,"type":22},"2025-03-01",{"date":42,"type":22},"2025-09-01",{"name":44,"class":45},"King Abdulaziz Medical City","OTHER_GOV",""]