[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"King Abdullah International Medical Research Center\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":121},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,46,69,94],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":45},"100565624","wireless-monitoring-for-clinical-deterioration-100565624",false,"NCT06644599","Wireless Monitoring for Clinical Deterioration","Integrated Proactive Wireless Monitoring for Clinical Deterioration: A Stepped Wedge Randomized Trial","i-PROTECT","Inclusion Criteria:\n\nWard level Inpatient wards, defined as wards used to manage adult inpatients.\n\nPatient level\n\n1. Aged 14 years or older\n2. Checked in as inpatient status to one of the study wards\n\nExclusion Criteria:\n\nWard level\n\n1. Cardiology, pediatric, obstetric wards\n2. ICUs and emergency departments\n3. Operating rooms\n4. Outpatient clinics\n5. Daycare wards, endoscopy, outpatient procedure areas, hemodialysis units\n\nPatient level No commitment for full life support at the time of arrival to the study ward (designated as Do-Not-Resuscitate status)","ALL","14 Years",{"count":20,"type":21},13160,"ESTIMATED","INTERVENTIONAL",[24],"NA","The study evaluates whether implementing a wireless monitoring system for patients admitted to hospital wards reduces mortality and cardiopulmonary failure.",[27],"Inpatient Facililty Diagnoses",[29,30,31,32],"inpatients","wireless monitoring","mortality","cardiopulmonary failure","RECRUITING","2026-02-25",{"date":36,"type":37},"2026-02-27","ACTUAL",{"date":39,"type":37},"2026-02-01",{"date":41,"type":21},"2026-12",{"name":43,"class":44},"King Abdullah International Medical Research Center","OTHER",1,{"id":47,"slug":48,"hasResults":11,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":52,"eligibilityCriteria":53,"healthyVolunteers":11,"sex":17,"minAge":54,"maxAge":4,"enrollmentInfo":55,"targetDuration":4,"studyType":22,"phases":57,"briefSummary":58,"conditions":59,"keywords":4,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":62,"lastUpdatePostDateStruct":63,"startDateStruct":65,"completionDateStruct":67,"leadSponsor":68,"locationsCount":45},"100447920","diagnosing-deep-vein-thrombosis-early-in-critically-ill-patients-100447920","NCT05112705","Diagnosing Deep-vein Thrombosis Early in Critically Ill Patients","Diagnosing Deep-vein Thrombosis Early in Critically Ill Patients (DETECT) Trial","DETECT","Inclusion criteria\n\n1. Medical, surgical or trauma ICU patients ≥18 years old.\n2. Patients who are expected to stay in the ICU more than 2 calendar days (unlikely to be discharged out of ICU on the day of admission or on the next day).\n\nExclusion Criteria\n\n1. Patients with DVT or PE diagnosed within the last year.\n2. Patients receiving chronic systemic anticoagulation.\n3. Patients who have received up to the time of ICU admission or are receiving therapeutic doses of anticoagulation with UFH, LMWH, or other anticoagulants.\n4. Inability or contraindication to obtain adequate ultrasound on the lower extremities (Burns in the lower extremities, lacerations, active skin infection, \\& ischemic limb in the legs, large dressings in the thighs that prevent adequate ultrasounds OR amputated foot or leg on one or two sides)\n5. Patients with Inferior Vena Cava (IVC) Filter.\n6. Known or suspected pregnancy.\n7. Limitation of life support, life expectancy \\\u003C7 days or palliative care.\n8. Previously enrolled in DETECT trial within the last 180 days.\n9. Enrolled in another trial for which co-enrolment is not approved.","18 Years",{"count":56,"type":21},1800,[24],"The DETECT randomized controlled trial addresses the question of whether surveillance ultrasound in critically ill patients by facilitating DVT detection reduces the incidence of PE and lowers all-cause 90-day mortality. The primary outcome is 90-day all-cause mortality.",[60,61],"Deep Vein Thrombosis","Pulmonary Embolism","2025-09-15",{"date":64,"type":37},"2025-09-19",{"date":66,"type":37},"2023-03-21",{"date":41,"type":21},{"name":43,"class":44},{"id":70,"slug":71,"hasResults":11,"nctId":72,"briefTitle":73,"officialTitle":74,"acronym":75,"eligibilityCriteria":76,"healthyVolunteers":77,"sex":17,"minAge":54,"maxAge":4,"enrollmentInfo":78,"targetDuration":4,"studyType":22,"phases":80,"briefSummary":81,"conditions":82,"keywords":4,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":85,"lastUpdatePostDateStruct":86,"startDateStruct":88,"completionDateStruct":90,"leadSponsor":92,"locationsCount":93},"100399015","replacing-protein-via-enteral-nutrition-in-critically-ill-patients-100399015","NCT04475666","Replacing Protein Via Enteral Nutrition in Critically Ill Patients","Replacing Protein Via Enteral Nutrition in a Stepwise Approach in Critically Ill Patients: An International, Multicenter Randomized Controlled Trial","REPLENISH","Inclusion Criteria(on ICU calendar day 4 or the morning of day 5)\n\n1. Age ≥18-years old\n2. Patient started on enteral nutrition (EN) via nasogastric\u002Forogastric or duodenal or percutaneous endoscopic gastrostomy (PEG) or jejunostomy tubes.\n3. The patient is on invasive mechanical ventilation and unlikely to be discharged from ICU next day.\n\nExclusion Criteria:\n\n1. Lack of commitment to full life support or brain death. Patients with \"Do Not Resuscitate\" order but with commitment to ongoing life support can be enrolled.\n2. Patients on any amount of parenteral nutrition (PN) in ICU at the time of screening, whether PN is used alone or in combination with enteral nutrition. Non-nutritional calories (dextrose, propofol, citrate) not considered as PN.\n3. Patients who received an average protein of more than 0.8g\u002Fkg\u002Fday in the first 4 ICU days.\n4. Patients being fed entirely through oral route - i.e. those who are eating.\n5. Pregnancy.\n6. Burn patients.\n7. Prisoners or those undergoing forced treatment.\n8. Patients with hepatic encephalopathy or Child C liver cirrhosis\n9. Inherited defect of amino acid metabolism.\n10. Allergies to protein supplement",true,{"count":79,"type":21},2502,[24],"The investigator will investigate the effect of supplemental enteral protein (1.2 g\u002Fkg\u002Fday) added to standard formula to achieve high amount of enteral protein (range 2-2.4 g\u002Fkg\u002Fday) given from ICU day 5 until ICU discharge up to ICU day 90 as compared to no supplemental enteral protein to achieve moderate amount enteral protein (0.8-1.2 g\u002Fkg\u002Fday), given in conjunction with similar amounts of stepwise caloric administration in the two groups on all-cause 90-day mortality.",[83,84],"Critical Illness","Nutrition Disorders","2025-08-31",{"date":87,"type":37},"2025-09-08",{"date":89,"type":37},"2020-09-21",{"date":91,"type":21},"2026-04-30",{"name":43,"class":44},2,{"id":95,"slug":96,"hasResults":11,"nctId":97,"briefTitle":98,"officialTitle":98,"acronym":4,"eligibilityCriteria":99,"healthyVolunteers":11,"sex":17,"minAge":54,"maxAge":100,"enrollmentInfo":101,"targetDuration":4,"studyType":22,"phases":103,"briefSummary":105,"conditions":106,"keywords":4,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":113,"lastUpdatePostDateStruct":114,"startDateStruct":116,"completionDateStruct":118,"leadSponsor":120,"locationsCount":45},"100599804","phase-4-the-perioperative-outcome-of-epinephrine-infusion-and-tranexamic-acid-in-knee-arthroplasty-surgery-100599804","NCT07089251","The Perioperative Outcome of Epinephrine Infusion and Tranexamic Acid in Knee Arthroplasty Surgery","Inclusion Criteria:\n\n* Patients undergoing knee joint arthroplasty.\n* Saudi and Non-Saudi Patient.\n* Patients who have Complete medical record.\n\nExclusion Criteria:\n\n* End stage renal disease\n* Liver cirrhosis\n* Coagulopathy\n* Pre-operative Hgb \\\u003C10 5.\n* History of cerebrovascular accident or myocardial infarction in past 12 months.\n* History of Heart failure.\n* History of arrhythmia.\n* History of pheochromocytoma, thyrotoxicosis and glaucoma.\n* Pregnancy or breast feeding\n* History of Deep venous thrombosis or pulmonary embolism\n* Allergy to epinephrine or tranexamic acid","70 Years",{"count":102,"type":21},80,[104],"PHASE4","The aim of this clinical trial is to evaluate the effect of administering low-dose epinephrine and tranexamic acid on perioperative blood loss, thromboembolic complications, and hospitalization duration in patients undergoing knee joint arthroplasty.\n\nAlso aim to evaluate the effect of administering low-dose epinephrine and tranexamic acid on perioperative thromboembolic complications, and hospitalization duration",[107,108,109,110,111,112],"Knee Arthroplasty, Total","Knee Arthritis, Osteoarthritis","Total Knee Anthroplasty","Blood Loss","Tranexamic Acid Use","Epinephrine","2025-07-21",{"date":115,"type":37},"2025-07-28",{"date":117,"type":37},"2025-07-15",{"date":119,"type":21},"2027-06-24",{"name":43,"class":44},""]