[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"King Abdullah University Hospital\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":376},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,14,0,[8,47,76,113,139,165,190,216,237,265,286,312,335,355],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":29,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100639358","early-phase-1-the-role-intraoperative-salbutamol-inhaler-in-preventing-atelectasis-100639358",false,"NCT07591558","The Role Intraoperative Salbutamol Inhaler in Preventing Atelectasis","The Role Intraoperative Salbutamol Inhaler Usage as Part of Intraoperative Regimen in Preventing Atelectasis Following Thoracic, Abdominal and Spinal Surgery in Diabetics Population","Inclusion Criteria:\n\n* The study will include patients aged 18-70 years\n* American Society of Anesthesiologists (ASA) physical status of I or II\n* Will undergo thoracic, abdominal or spinal surgery\n\nExclusion Criteria:\n\n* cardiac conditions other than hypertension like arrhythmia\n* previous cardiac surgeries and valvular heart diseases","ALL","18 Years","70 Years",{"count":20,"type":21},80,"ESTIMATED","INTERVENTIONAL",[24],"EARLY_PHASE1","Atelectasis is considered a common complication in the perioperative period, especially following surgeries under general anesthesia. Postoperative atelectasis could occur anytime during the perioperative period from intraoperative period to 24 hours postoperative and contribute to a variety of other complications, including hypoxemia and pneumonia. In the literature, several methods were utilized to combat this phenomenon, therefore, we investigate the role of intraoperative salbutamol in reducing the incidence of atelectasis. It is well known that salbutamol could be an adjunctive bronchodilator medication used in the intraoperative anesthetic regimens.",[27,28],"Atelectases, Postoperative Pulmonary","Diabete Mellitus",[30,31,32,33],"atelectasis","salbutamol","pulmonary","bronchodilator","NOT_YET_RECRUITING","2026-05-11",{"date":37,"type":38},"2026-05-15","ACTUAL",{"date":40,"type":21},"2026-06",{"date":42,"type":21},"2026-12",{"name":44,"class":45},"King Abdullah University Hospital","OTHER",1,{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":4,"eligibilityCriteria":53,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":54,"enrollmentInfo":55,"targetDuration":4,"studyType":22,"phases":57,"briefSummary":58,"conditions":59,"keywords":62,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":71,"completionDateStruct":73,"leadSponsor":75,"locationsCount":46},"100625998","early-phase-1-ketamine-for-shoulder-pain-following-laparoscopic-gastric-sleeve-surgery-100625998","NCT07429916","Ketamine for Shoulder Pain Following Laparoscopic Gastric Sleeve Surgery","The Role of Intraoperative Ketamine Usage as Part of Anesthetic Management in Decreasing the Incidence of Shoulder Pain Following Laparoscopic Gastric Sleeve Surgery","Inclusion Criteria:\n\n* patients aged 18-60\n* American society of anesthesiologist grade 1,2\n* BMI \\> 40\n* BMI \\> 35 with obesity-related comorbidities\n\nExclusion Criteria:\n\n* mentally incapacitated\n* patients received any type of analgesia 24hr preoperatively except paracetamol\n* history of drug abuse\n* patients with low ejection fraction","60 Years",{"count":56,"type":21},50,[24],"Shoulder pain is a well-recognized complaint following laparoscopic surgery. It is underlying mechanism has various causes, therefore, modalities in management and prevention of this sort of pain are numerous with different success rates. In the light of this, the investigators aim to compare an anesthetic management plan involving using ketamine (which is a known intraoperative anesthetic agent) to another not involving it for participants undergoing gastric sleeve, and compare the incidence and intensity of shoulder pain afterwards.",[60,61],"Pain Management","Laparascopic Sleeve Gastrectomy",[63,64,65,66],"Shoulder pain","ketamine","Postoperative","Gastrectomy","RECRUITING","2026-02-22",{"date":70,"type":38},"2026-02-24",{"date":72,"type":38},"2026-01-01",{"date":74,"type":21},"2026-08-30",{"name":44,"class":45},{"id":77,"slug":78,"hasResults":11,"nctId":79,"briefTitle":80,"officialTitle":81,"acronym":4,"eligibilityCriteria":82,"healthyVolunteers":83,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":84,"targetDuration":4,"studyType":22,"phases":86,"briefSummary":88,"conditions":89,"keywords":96,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":106,"lastUpdatePostDateStruct":107,"startDateStruct":109,"completionDateStruct":111,"leadSponsor":112,"locationsCount":46},"100620972","the-antiplaque-and-antigingivitis-effect-of-pure-green-tea-mouth-wash-compared-to-placebo-and-essential-oils-mouth-washes-100620972","NCT07364565","The Antiplaque and Antigingivitis Effect of Pure Green Tea Mouth Wash Compared to Placebo and Essential Oils Mouth Washes","The Antiplaque and Antigingivitis Effect of Pure Green Tea Mouth Wash Compared to Placebo and Essential Oils Mouth Washes: A Double Blinded Randomized Controlled Clinical Trial.","Inclusion criteria:\n\n* Non-smokers\n* Systemically healthy\n* At least 24 teeth in the functional dentition, excluding third molars\n* Clinical diagnosis of periodontal health (no periodontal pockets \\> 3 mm, bleeding on probing percentage \\\u003C 10%, and no attachment loss).\n\nExclusion criteria:\n\n* Smokers.\n* Medically compromised patients.\n* Pregnant woman.\n* Allergies to green tea or EO.\n* Any condition that might affect the periodontal tissues.\n* Patients with any carious lesions (initial or active).\n* Patients who have overhang restorations, poorly designed crowns or bridges, and ortho retainers.\n* Use of systemic antibiotics or anti-inflammatory medications within 3 months prior to enrolment.",true,{"count":85,"type":21},44,[87],"NA","The goal of this clinical trial is to to evaluate the antiplaque and antigingivitis effect of pure green tea mouthwash compared to placebo and essential oils mouthwashes in healthy patients.\n\nThe main questions it aims to answer are:\n\n* Does pure green tea mouthwash effectively reduce dental plaque?\n* Does pure green tea mouthwash reduce gingival inflammation?\n\nResearchers will compare pure green tea mouthwash to Listerine Total Care, Listerine Green Tea, and placebo to see if there is a difference in plaque accumulation and gum inflammation reduction.\n\nParticipants will be prohibited from using any sort of oral hygiene parctice for the whole study period (3 weeks). Instead, they will rinse with 10 ml of their assigned mouthwash twice daily for 30 seconds. Plaque index, gingival index, and staining index will be examined at multiple intervals and participants will rate their sense of oral freshness and good breath.",[90,91,92,93,94,95],"Dental Plaque","Patient Reported Outcome","Gingival Inflammation and Bleeding","Gingival Inflammation","Gingival Bleeding","Gingivitis",[97,98,99,100,101,102,103,104,105],"Green tea","Gingival inflammation","Plaque index","Essential oils","Mouthwash","Bleeding on probing","Camellia sinensis","Herbal medicine","Periodontal health","2026-01-21",{"date":108,"type":38},"2026-01-23",{"date":110,"type":38},"2025-12-01",{"date":42,"type":21},{"name":44,"class":45},{"id":114,"slug":115,"hasResults":11,"nctId":116,"briefTitle":117,"officialTitle":118,"acronym":4,"eligibilityCriteria":119,"healthyVolunteers":83,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":120,"targetDuration":4,"studyType":22,"phases":122,"briefSummary":123,"conditions":124,"keywords":129,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":106,"lastUpdatePostDateStruct":134,"startDateStruct":135,"completionDateStruct":137,"leadSponsor":138,"locationsCount":46},"100618325","the-effectiveness-of-nano-bio-fusion-gingival-gel-nbf-on-wound-healing-at-the-palate-donor-site-after-soft-tissue-graft-surgery-compared-to-placebo-gel-100618325","NCT07330154","The Effectiveness of Nano Bio Fusion Gingival Gel (NBF) on Wound Healing at the Palate (Donor Site) After Soft Tissue Graft Surgery Compared to Placebo Gel.","The Effectiveness of Nano Bio Fusion Gel (NBF) on Early Wound Healing at the Palate (Donor Site) After Soft Tissue Graft Surgery Compared to Placebo Gel: a Double Blinded Randomized Controlled Clinical Trial","Inclusion Criteria:\n\n1. Patients with gingival recession that is indicated for root coverage or need for phenotype modification.\n2. 18 years or older.\n3. absence of systemic disease\n4. Non-smoker\n5. No use of antibiotics, corticosteroids, anti-inflammatory medication or hormones in the past 3 months\n\nExclusion Criteria:\n\n1. Pregnant or lactating woman.\n2. patients with immune or systemic diseases.\n3. Patients with an allergy to any ingredient in the gel.",{"count":121,"type":21},36,[87],"The goal of this clinical trial is to assess the effect of Nano-biofusion gingival gel (NBF) on wound healing at the palatal donor site following soft tissue graft surgery and compare it to placebo gel. The main questions it aims to answer are:\n\n* Does NBF gel enhance wound healing after graft harvesting from the palate?\n* Does NBF gel reduce the number of inflammatory mediators after surgery?\n* Does NBF gel reduce pain and discomfort at the palatal donor site? Researchers will compare NBF gel to a placebo (a look-alike gel that does not contain the active ingredients) to see if NBF gel enhances wound healing.\n\nStudy steps include:\n\n* Participants will apply the assigned gel on the surgical wound 4 times a day for 4 weeks.\n* Clinical photographs and measurements will be obtained on days (0, 1, 2, 4, 7, 15, 21, 30).\n* Wound fluid samples will be collected on days (0, 1, 2, 4, 7).\n* Participants will be asked about the level of pain and analgesic consumption on each follow-up visit.",[125,126,127,128],"Wound Healing","Palatal Wound","Donor Site Complication","Inflammatory Cytokines",[130,131,132,133],"NBF gel","wound healing","palatal donor site","soft tissue graft",{"date":108,"type":38},{"date":136,"type":38},"2025-10-29",{"date":42,"type":21},{"name":44,"class":45},{"id":140,"slug":141,"hasResults":11,"nctId":142,"briefTitle":143,"officialTitle":144,"acronym":4,"eligibilityCriteria":145,"healthyVolunteers":83,"sex":16,"minAge":17,"maxAge":146,"enrollmentInfo":147,"targetDuration":4,"studyType":22,"phases":149,"briefSummary":150,"conditions":151,"keywords":153,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":157,"lastUpdatePostDateStruct":158,"startDateStruct":160,"completionDateStruct":162,"leadSponsor":164,"locationsCount":46},"100606264","the-effect-of-bleaching-application-mode-on-bleaching-induced-tooth-sensitivity-100606264","NCT07173296","The Effect of Bleaching Application Mode on Bleaching-induced Tooth Sensitivity.","The Effect of Single and Multiple Application of In-office Dental Bleaching on Tooth Sensitivity and Bleaching Efficacy: a Single-blind Randomized Controlled Trial","Inclusion Criteria:\n\n* At least eight maxillary anterior teeth present.\n* Age over 18\n* The selected teeth have a mean shade of C2 or darker.\n* Good general and oral health. (no visible plaque or gingivitis)\n* No restorations or carious lesions on the buccal surfaces of the anterior teeth to be whitened\n* No history of tooth sensitivity\n* No use of a desensitizing agent or desensitizing toothpaste in the past six months\n* No use of pain killer for the last 48 hours\n\nExclusion Criteria:\n\n* Active caries and\u002For periodontal diseases (gingivitis and recession) or wasting diseases\n* Smokers\n* Pregnant\u002Flactating women.\n* Patients who have bleached their teeth previously.\n* No schedule availability","35 Years",{"count":148,"type":21},60,[87],"The aim of this study is to evaluate the effect of single versus multiple application protocols for in-office dental bleaching using two different bleaching gels (Pola Office Plus, SDI, 37.5% HP and Opalescence Boost, Ultradent, 40% HP) on the risk and intensity of tooth sensitivity, as well as the effect of the application protocol on the bleaching efficacy.\n\nNull hypothesis: There is no difference in intensity and risk of tooth sensitivity between single and multiple application of each gel and the application protocol dose not present significant effect on the bleaching efficacy.",[152],"Tooth Sensitivity",[154,155,156],"Sensitivity","Application mode","in-office bleaching","2025-09-07",{"date":159,"type":38},"2025-09-15",{"date":161,"type":38},"2025-01-01",{"date":163,"type":21},"2026-09-30",{"name":44,"class":45},{"id":166,"slug":167,"hasResults":11,"nctId":168,"briefTitle":169,"officialTitle":170,"acronym":4,"eligibilityCriteria":171,"healthyVolunteers":83,"sex":16,"minAge":17,"maxAge":172,"enrollmentInfo":173,"targetDuration":4,"studyType":22,"phases":175,"briefSummary":176,"conditions":177,"keywords":180,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":182,"lastUpdatePostDateStruct":183,"startDateStruct":185,"completionDateStruct":187,"leadSponsor":189,"locationsCount":46},"100508255","postoperative-symptoms-following-endodontic-microsurgery-100508255","NCT05898035","Postoperative Symptoms Following Endodontic Microsurgery","Postoperative Symptoms Following Endodontic Microsurgery Performed by Piezoelectric Osteotomy Versus Conventional Osteotomy: A Randomized Clinical Trial","Inclusion Criteria:\n\n* Non-smokers .\n* Teeth that are periodontally healthy.\n* Age (18-65)\n\nExclusion Criteria:\n\n* Patients with an active systematic diseases that may affect the outcome\n* Medically compromised patients on long term medications.\n* Patients who had received analgesics or antibiotics prior to surgery will be postponed.\n* Cases where orthograde endodontic treatment is feasible\n* Teeth with poor prognosis.\n* Teeth with an active periodontal disease (pocket depth \\> 5 mm).\n* Emotionally distressed patients.","65 Years",{"count":174,"type":21},40,[87],"Aims: The purpose of this randomized clinical trial is to assess and compare the post operative pain, swelling and quality of life after endodontic microsurgery using either conventional osteotomy or piezoelectric osteotomy . The PICO question that will be used is Does endodontic microsurgery using piezoelectric osteotomy have similar clinical performance in terms of post operative pain and swelling to that of endodontic microsurgery using conventional hand-piece osteotomy.\n\nMaterial and methods:\n\nbased on solid inclusion criteria , a total of 44 patients in need of endodontic microsurgery will be randomly distributed into two groups (n=22) according to the osteotomy technique: conventional and piezoelectric osteotomy. A standardized microsurgical technique will be employed. After the microsurgery procedure, a pain questionnaire that contain visual analogue scale will be given to each patient to evaluate the pain incidence and intensity at 5 time intervals, 24 hours, 48 hours, 72 hours, 96 hours and 120 hours. The patients will be recalled as well, at days 2 and 7 to evaluate the swelling. Statistical analysis will be performed using chi-square test and linear regression analysis.",[178,179],"Pain Postoperative","Swelling Lips & Face",[181],"Microsurgery, Pain, swelling, Piezo surgery","2025-04-04",{"date":184,"type":38},"2025-04-08",{"date":186,"type":38},"2022-02-01",{"date":188,"type":21},"2025-09",{"name":44,"class":45},{"id":191,"slug":192,"hasResults":11,"nctId":193,"briefTitle":194,"officialTitle":195,"acronym":4,"eligibilityCriteria":196,"healthyVolunteers":83,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":197,"targetDuration":4,"studyType":22,"phases":199,"briefSummary":200,"conditions":201,"keywords":203,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":208,"lastUpdatePostDateStruct":209,"startDateStruct":211,"completionDateStruct":213,"leadSponsor":215,"locationsCount":46},"100584090","clinical-evaluation-of-color-adjusting-composite-resin-following-in-office-dental-bleaching-100584090","NCT06884813","Clinical Evaluation of Color-Adjusting Composite Resin Following In-Office Dental Bleaching","Clinical Evaluation of a Single-Shade, Color-Adjusting Composite Resin Following In-Office Dental Bleaching: A Randomized Clinical Trial","Inclusion Criteria:\n\n1. Patients who are willing to come back for follow-up appointments.\n2. Patients who are willing to sign an informed consent form.\n3. Patients with well documented clinical records and have at least two anterior restorations (both Omnichroma and conventional multi-shade nanohybrid composite.)\n4. Patients aged 18 years or older.\n5. Patients with good oral hygiene\n6. Patients with vital teeth.\n7. Patients who are willing to have the restorations replaced later if necessary if there is a color mismatch after bleaching treatment.\n\nExclusion Criteria:\n\n1. Individuals with severe bruxism or periodontal disease.\n2. Patients with non-vital teeth restored with composite fillings.\n3. Patients with severe tooth discoloration.\n4. Patients with fluorosis or tetracycline staining.\n5. Heavy smokers.\n6. Pregnant or nursing women.\n7. Patients undergoing orthodontic treatment.\n8. Patients with enamel or dentin deformations.",{"count":198,"type":21},120,[87],"One challenge faced by dental professionals is that, unlike natural tooth structure, composite restorations do not lighten when exposed to bleaching agents. As a result, functional restorations may need replacement after bleaching to match the newly whitened teeth. However, replacing a composite restoration can lead to unnecessary removal of tooth structure, potentially weakening the tooth and increasing its susceptibility to further iatrogenic damage. This study will investigate the ability of Omnichroma restorations to shade-match tooth structure after bleaching.\n\nThe null hypotheses will be:\n\n1. Single-shade RBC will not exhibit similar shade and optical behavior to conventional RBC across all anterior restorations following bleaching.\n2. Patient satisfaction regarding color blending between the restoration and tooth structure will not differ according to the type of material used.\n3. Dentist satisfaction regarding color blending between the restoration and tooth structure will not differ according to the type of material used.",[202],"Composite Resins",[204,205,206,207],"Single-shade composite","Bleaching","clinical trial","Shade matching","2025-03-19",{"date":210,"type":38},"2025-03-24",{"date":212,"type":38},"2025-03-10",{"date":214,"type":21},"2026-08-01",{"name":44,"class":45},{"id":217,"slug":218,"hasResults":11,"nctId":219,"briefTitle":220,"officialTitle":221,"acronym":4,"eligibilityCriteria":222,"healthyVolunteers":83,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":223,"targetDuration":4,"studyType":22,"phases":224,"briefSummary":225,"conditions":226,"keywords":227,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":232,"lastUpdatePostDateStruct":233,"startDateStruct":234,"completionDateStruct":235,"leadSponsor":236,"locationsCount":46},"100584088","color-adjusting-resin-composite-in-anterior-tooth-restorations-clinical-and-subjective-evaluations-100584088","NCT06884787","Color Adjusting Resin Composite in Anterior Tooth Restorations: Clinical and Subjective Evaluations","Clinical and Subjective Evaluations of a Universal-Shade, Color Adjusting Resin Composite in Anterior Tooth Restorations: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Patients attending the dental clinics at JUST in Irbid or on the university campus.\n* Patients aged 18 years and older.\n* Patients with good oral hygiene.\n* Patients with a positive attitude towards dental treatment.\n* Patients require restorations on at least two anterior teeth.\n* Patients with spaces between teeth that do not require orthodontic treatment for correction.\n* Patients with healthy pulp or reversible pulpitis.\n* Patients without any periapical lesions\n\nExclusion Criteria:\n\n* Teeth with enamel or dentin deformations.\n* Teeth affected by fluorosis or tetracycline staining.\n* Teeth with severe discoloration.\n* Primary teeth.\n* Patients with gingival inflammation or periodontal disease.\n* Patients undergoing active orthodontic treatment.\n* Heavy smokers.\n* Very deep or very shallow cavities.\n* Class IV cavities where more than half of the tooth surface is lost.\n* Traumatic Class IV cavities with pulp exposure.\n* Class III cavities that do not open labially.",{"count":198,"type":21},[87],"The ability of single-shade composite restorations to blend with adjacent tooth structure shades is called chameleon effect. This effect is enhanced using specially designed spherical particles in the composite material which will help diffuse light in a way that mimics the natural color and translucency of teeth making the restoration nearly imperceptible to the naked eye.\n\nThe hypotheses of the investigation are as follow:\n\n* Single-shade RBC exhibits similar shade matching and optical behavior to conventional RBC across all anterior restorations.\n* Patient satisfaction regarding color blending between the restoration and tooth structure is comparable regardless of the type of material used.\n* Dentist satisfaction regarding color blending is similar for both single-shade RBC and conventional RBC materials.",[202],[228,229,230,231],"Single-sahde composite","Color adaptability,","Objective and subjective analysis","anterior restorations","2025-03-18",{"date":208,"type":38},{"date":212,"type":38},{"date":214,"type":21},{"name":44,"class":45},{"id":238,"slug":239,"hasResults":11,"nctId":240,"briefTitle":241,"officialTitle":242,"acronym":4,"eligibilityCriteria":243,"healthyVolunteers":83,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":244,"targetDuration":4,"studyType":22,"phases":246,"briefSummary":247,"conditions":248,"keywords":250,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":257,"lastUpdatePostDateStruct":258,"startDateStruct":260,"completionDateStruct":262,"leadSponsor":264,"locationsCount":46},"100551257","the-performance-of-posterior-partial-coverage-coronal-restorations-luted-with-two-differrent-systems-100551257","NCT06457737","The Performance of Posterior Partial Coverage Coronal Restorations Luted With Two Differrent Systems.","The Performance of Posterior Partial Coverage Coronal Restorations Cemented Using Two Different Luting Systems. A Comparative Clinical Trial.","Inclusion Criteria:\n\n* Consenting participants.\n* Individuals aged 18 years and above with no systemic diseases that will affect their participation.\n* Teeth of healthy periodontium.\n* Teeth to be restored in normal occlusion with natural antagonist and adjacent teeth.\n* Acceptable oral hygiene characterized by no gingivitis, calculus deposit or active carious lesions.\n* Non-vital teeth will be included\n\nExclusion Criteria:\n\n* Heavy occlusal contacts or signs of bruxism.\n* Profound, chronic periodontitis\n* Poor oral hygiene.\n* Sustained dentin hypersensitivity.\n* Systemic disease or severe medical complications or taking anti-inflammatory, analgesic, or psychotropic drugs.",{"count":245,"type":21},70,[87],"This study explores an alternative approach using a pre-heated restorative resin composite as a luting material of partial coverage restorations on upper and lower posterior teeth. It will follow a split-mouth design with 60 participants selected based on strict criteria. Assessment at 6 months and 1 year post-delivery utilizes a modified model of USPHS criteria, evaluating retention, color match, marginal discoloration, secondary caries, anatomical form, marginal adaptation, and surface roughness.\n\nThe null hypothesis:\n\nThe use of preheated resin composite for cementing partial coverage restoration will not result in significantly superior clinical performance when compared to that after using dual-cure resin cement.",[249],"Unsatisfactory or Defective Restoration of Tooth",[251,252,253,254,255,256],"Endodontically treated teeth","Partial coverage","Ceramic restorations","Luting systems","Preheated composite","Dual cure adhesive resin cement","2025-03-13",{"date":259,"type":38},"2025-03-14",{"date":261,"type":38},"2024-05-01",{"date":263,"type":21},"2026-02-28",{"name":44,"class":45},{"id":266,"slug":267,"hasResults":11,"nctId":268,"briefTitle":269,"officialTitle":269,"acronym":4,"eligibilityCriteria":270,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":271,"enrollmentInfo":272,"targetDuration":4,"studyType":274,"phases":4,"briefSummary":275,"conditions":276,"keywords":4,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":278,"lastUpdatePostDateStruct":279,"startDateStruct":281,"completionDateStruct":283,"leadSponsor":285,"locationsCount":46},"100560556","factors-and-consequences-associated-with-diabetic-foot-problems-among-diabetic-patients-in-jordan-100560556","NCT06578689","Factors and Consequences Associated With Diabetic Foot Problems Among Diabetic Patients in Jordan","Inclusion Criteria:\n\n* Adults DM (1 year)\n\nHave a mobile phone\n\nExclusion Criteria:\n\n* Cognitive impairment","90 Years",{"count":273,"type":21},200,"OBSERVATIONAL","Purpose: To assess diabetic foot ulcers (DFU)-related risk factors and complications among diabetes mellitus (DM) patients in Northern Jordan. Also, to analyze the impact of educational intervention on their behavior.\n\nMethods: The study consisted of two phases. Phase one was a prospective cross-sectional study of 200 DM patients, including 94 with a history of DFU, where demographic and clinical data were collected to assess diabetic foot-associated risk factors and complications. Phase two was a randomized clinical trial with 105 DM patients: 52 in the control group received standard care, while 53 in the intervention group received standard care supplemented with formal educational session and ongoing foot care education via mobile health by a clinical pharmacist. Foot care practices and medication adherence were evaluated at baseline and after 8 weeks of follow-up.",[277],"Diabetic Foot","2024-08-27",{"date":280,"type":38},"2024-08-29",{"date":282,"type":38},"2024-01-01",{"date":284,"type":21},"2025-12-31",{"name":44,"class":45},{"id":287,"slug":288,"hasResults":11,"nctId":289,"briefTitle":290,"officialTitle":291,"acronym":4,"eligibilityCriteria":292,"healthyVolunteers":83,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":293,"targetDuration":4,"studyType":22,"phases":295,"briefSummary":296,"conditions":297,"keywords":300,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":304,"lastUpdatePostDateStruct":305,"startDateStruct":307,"completionDateStruct":309,"leadSponsor":311,"locationsCount":46},"100557038","color-stability-and-wear-resistance-of-direct-flowable-and-preheated-composite-using-the-injectable-technique-100557038","NCT06532916","Color Stability and Wear Resistance of Direct Flowable and Preheated Composite Using the Injectable Technique","Color Stability and Wear Resistance of Direct Flowable and Preheated Resin Composite Veneers Using the Injectable Resin Technique: A Randomized Controlled Clinical Trial.","Inclusion Criteria:\n\n* Patients older than 18 years\n* Asymptomatic sound anterior teeth, or localized Class III\u002FIV\u002FV cavity or restoration\n* Patients with irregular tooth anatomies, misalignments, spacing, mild staining, cervical wear that are indicated for direct composite veneers\n* Restorations in functional occlusions with an opposing natural tooth.\n* Two proximal contacts area with neighboring teeth\n\nExclusion Criteria:\n\n* Patients with contra-indications for regular dental treatment based on their medical history.\n* Patients at a high risk of caries.\n* Patients with poor oral hygiene.\n* Teeth with compromised periodontal status.\n* Evidence of active parafunctional habits or excessive tooth wear.\n* Severe discoloration\n* Heavy smokers\n* Patients with special aesthetic requirements that could not be solved by direct composite veneers.",{"count":294,"type":21},142,[87],"The aim of this study is to conduct the first clinical trial to assess the color stability and wear resistance of the highly filled injectable flowable composite materials compared to preheated conventional ones and evaluate the in vivo performance of the injectable composite technique.",[298,299],"Resin Composite Restorations","Esthetic Restorations",[301,302,303],"Resin composites","Injectable resins","Preheated resins","2024-08-02",{"date":306,"type":38},"2024-08-06",{"date":308,"type":38},"2014-03-01",{"date":310,"type":21},"2026-03-01",{"name":44,"class":45},{"id":313,"slug":314,"hasResults":11,"nctId":315,"briefTitle":316,"officialTitle":317,"acronym":4,"eligibilityCriteria":318,"healthyVolunteers":83,"sex":16,"minAge":17,"maxAge":146,"enrollmentInfo":319,"targetDuration":4,"studyType":22,"phases":321,"briefSummary":322,"conditions":323,"keywords":325,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":327,"lastUpdatePostDateStruct":328,"startDateStruct":330,"completionDateStruct":332,"leadSponsor":334,"locationsCount":46},"100557008","effects-of-bio-active-desensitizer-on-reduction-of-tooth-sensitivity-caused-by-in-office-bleaching-100557008","NCT06532526","Effects of Bio-active Desensitizer on Reduction of Tooth Sensitivity Caused by In-office Bleaching.","Assessment of the Effects of Bio-active Desensitizing Materials on the Bleaching Efficacy and Reduction of Tooth Sensitivity Caused by Vital In-office Bleaching: A Randomized Controlled Clinical Trial","Inclusion Criteria:\n\n* At least eight maxillary anterior teeth present.\n* Age between 18 and 30 years Smokers\n* The selected teeth has a mean shade of C2 or darker (Vitapan Classical, Vita-Zahnfabrik, Sa¨ckingen, Germany)\n* Good general and oral health (no visible plaque or gingivitis)\n* No restorations or carious lesions on the buccal surfaces of the anterior teeth to be whitened\n* No history of tooth sensitivity\n* No use of a desensitizing agent or desensitizing toothpaste in the past six months\n\nExclusion Criteria:\n\n* Active caries and\u002For periodontal diseases (gingivitis and recession) or wasting diseases\n* Smokers\n* Pregnant\u002Flactating women\n* Patients who have bleached their teeth previously\n* No schedule availability",{"count":320,"type":21},51,[87],"The main aim of this randomized controlled clinical trial is to evaluate the efficacy of a bioactive glass desensitizer in reducing tooth sensitivity associated with in-office vital tooth bleaching. In addition, this study aims to compare the effectiveness of the bioactive glass desensitizer with that of a fluoride gel and a gel without desensitizing agent with regard to incidence, intensity, and duration of tooth sensitivity and, finally, to investigate how these agents affect tooth-shade following in-office bleaching. The hypothesis of the study is: There will be no difference in the effect of a bio-active glass desensitizer on tooth sensitivity associated with vital in-office tooth bleaching compared to a fluoride gel and the bio-active glass desensitizer has no effect on the bleaching efficacy.",[324],"Tooth Discoloration",[154,326,156],"Bio-active desensitizer","2024-07-29",{"date":329,"type":38},"2024-08-01",{"date":331,"type":38},"2024-07-01",{"date":333,"type":21},"2025-04-01",{"name":44,"class":45},{"id":336,"slug":337,"hasResults":11,"nctId":338,"briefTitle":339,"officialTitle":340,"acronym":4,"eligibilityCriteria":341,"healthyVolunteers":83,"sex":16,"minAge":17,"maxAge":172,"enrollmentInfo":342,"targetDuration":4,"studyType":22,"phases":343,"briefSummary":344,"conditions":345,"keywords":4,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":347,"lastUpdatePostDateStruct":348,"startDateStruct":350,"completionDateStruct":352,"leadSponsor":353,"locationsCount":354},"100518534","radiographic-assessment-of-the-healing-pattern-associated-with-periradicular-endodontic-microsurgery-100518534","NCT06031792","Radiographic Assessment of the Healing Pattern Associated With Periradicular Endodontic Microsurgery","A 2D and 3D Radiographic Assessment of the Healing Pattern Associated With Conventional and Piezoelectric Periradicular Endodontic Microsurgery","Inclusion Criteria:\n\n* Medically fit patients\n* Age (18-65 )\n* Teeth that are periodontally healthy\n* Coronally sealed root canal treated teeth\n\nExclusion Criteria:\n\n* Patients with an active systematic disease that may affect the short- and long-term outcomes or restrict surgical intervention\n* Emotionally distressed patients\n* Patients who had received analgesics or antibiotics prior to surgery will be postponed\n* Cases where orthograde endodontic treatment is feasible, will be retreated at the post-graduate clinics and not included in this study\n* Teeth with poor prognosis (e.g., non-restorable, vertical root fracture, short roots, non-strategic tooth, endo-perio lesion",{"count":85,"type":21},[87],"Endodontic periradicular microsurgery is a dental procedure to treat apical periodontitis in cases in which healing has not occurred after non-surgical treatment or if it is not feasible. Recent advances in techniques and materials have resulted in more predictable outcomes. Piezotome is a new and innovative device, but limited evidence is available regarding its use in endodontics. The aim of this study is to assess the healing pattern of conventional periradicular microsurgery and piezoelectric periradicular microsurgery in 2- Dimensional and 3-Dimensional imaging, and further to perform histological analysis for the presence, location, and arrangement of bacteria in the excised apical portion of the root canal system.",[346],"Periapical; Infection","2024-06-13",{"date":349,"type":38},"2024-06-17",{"date":351,"type":38},"2021-09-30",{"date":163,"type":21},{"name":44,"class":45},2,{"id":356,"slug":357,"hasResults":11,"nctId":358,"briefTitle":359,"officialTitle":360,"acronym":4,"eligibilityCriteria":361,"healthyVolunteers":83,"sex":16,"minAge":362,"maxAge":54,"enrollmentInfo":363,"targetDuration":4,"studyType":22,"phases":364,"briefSummary":365,"conditions":366,"keywords":4,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":368,"lastUpdatePostDateStruct":369,"startDateStruct":371,"completionDateStruct":373,"leadSponsor":375,"locationsCount":46},"100542805","outcome-of-pulp-revascularization-of-necrotic-mature-permanent-teeth-using-platelet-rich-fibrin-100542805","NCT06347640","Outcome of Pulp Revascularization of Necrotic Mature Permanent Teeth Using Platelet-rich Fibrin","The Outcome of Pulp Revascularization of Necrotic Mature Permanent Teeth With Periapical Lesion Using Platelet-rich Fibrin Versus Induced Bleeding: Randomized Clinical Trial","Inclusion Criteria\n\n1. Anterior or posterior mature tooth diagnosed with necrotic pulp in the presence of a periapical lesion,\n2. Pulp space is not needed for post and core restoration.\n3. Patients are not allergic to the medicaments necessary to complete the procedure.\n\nExclusion Criteria\n\n1. Medically compromised patient.\n2. Patient with generalized chronic periodontitis.\n3. Teeth with previous root canal treatment.\n4. Periodontal pocket larger than 3mm.\n5. Teeth with vertical fractures\n6. Non-restorable teeth","12 Years",{"count":56,"type":21},[87],"Regenerative endodontic procedures are intended to replace damaged tooth structures, including dentine and root structures, in addition to cells of the pulp-dentine complex. This treatment modality have been tested on immature necrotic teeth because they are anticipated to have a greater chance of pulp tissue regeneration.\n\nHowever, it has been recently suggested for treating fully formed mature necrotic permanent teeth with closed apices since the conventional root canal treatment yielded many drawbacks.\n\nA number of studies have evaluated the regeneration outcomes of using blood clot as a scaffold. However, there are limited studies in the literature on using other scaffolds such as platelet-rich fibrin (PRF).\n\nThis clinical study will evaluate clinically and radiographically the effectiveness of PRF versus induced bleeding in treating mature necrotic teeth. Fifty patients with necrotic mature teeth with periapical lesions will be invited to participate in this study. Teeth will be treated using calcium hydroxide as intracanal medicament then using PRF (n=25) and blood clot (n=25) as scaffold. All teeth will be sealed coronally using NeoMTA Plus™. Treated teeth will be assessed clinically and radiographically using 2D periapical radiographs. The reported clinical and radiographic outcomes will be compared using SPSS.",[367],"Pulp Revascularization","2024-04-02",{"date":370,"type":38},"2024-04-04",{"date":372,"type":38},"2023-04-01",{"date":374,"type":21},"2027-12-01",{"name":44,"class":45},""]