[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Kirby Mayer\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":76},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,47],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":24,"conditions":25,"keywords":28,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":5},"100581663","functional-incremental-stepping-in-place-test-f-ist-validation-100581663",false,"NCT06853236","Functional Incremental Stepping in Place Test (F-IST) Validation","A Cardiorespiratory Fitness Test for Acute Illness: Validity, Reliability, and Clinical Utility of Functional Incremental Stepping-in-Place Test","F-IST","Inclusion Criteria:\n\n-Currently able to walk with or without a walking aid, such as a cane or walker or rollator\n\nExclusion Criteria:\n\nPregnancy\n\nspecifically related to cardiopulmonary testing\n\n* A recent significant change in resting ECG\n* Unstable angina\n* Uncontrolled cardiac dysrhythmias causing symptoms or hemodynamic compromise\n* Symptomatic severe aortic stenosis\n* Uncontrolled symptomatic heart failure\n* Acute pulmonary embolus or pulmonary infarction\n* Acute myocarditis or pericarditis\n* Suspected or known dissecting aneurysm\n* Acute systemic infection accompanied by fever, body aches, or swollen lymph glands\n* Left Main Coronary Stenosis\n* Moderate stenotic valvular heart disease\n* Electrolyte abnormalities\n* Severe arterial hypertension (\\>200 systolic, \\>110 diastolic) at rest\n* Tachydysrhythmia or bradydysrhythmia\n* Hypertrophic cardiomyopathy and other forms of outflow tract obstruction\n* Neuromuscular, musculoskeletal, or rheumatic disorders that are exacerbated by exercise\n* High degree AV block\n* Ventricular aneurysm\n* Uncontrolled metabolic disease (diabetes, thyrotoxicosis, or myxedema)\n* Chronic infectious disease (hepatitis, AIDS, mono)\n* Mental or physical impairment leading to inability to exercise adequately",true,"ALL","18 Years",{"count":21,"type":22},60,"ESTIMATED","OBSERVATIONAL","The purpose of this multi-site prospective study is to assess validity of a new step test called Functional-Incremental Stepping-in-place- Test (F-IST) compared to gold-standard cardiopulmonary exercise testing (CPET) and to physical function and health perception, respectively. The investigators will also assess test-retest reliability of the F-IST. The investigators hypothesize that the F-IST will have high validity and test-retest reliability to be used in field testing environments such as the ICU.",[26,27],"Intensive Care Medicine","Acute Care Medical",[29,30,31,32,33,34],"Cardio respiratory fitness","incremental step test","validity","reliability","physical function","graded exercise testing","RECRUITING","2026-03-16",{"date":38,"type":39},"2026-03-17","ACTUAL",{"date":41,"type":39},"2024-07-02",{"date":43,"type":22},"2026-07-02",{"name":45,"class":46},"Kirby Mayer","OTHER",{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":53,"eligibilityCriteria":54,"healthyVolunteers":11,"sex":18,"minAge":19,"maxAge":55,"enrollmentInfo":56,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":58,"conditions":59,"keywords":62,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":75},"100583426","virtual-reality-in-icu---partner-100583426","NCT06876168","Virtual Reality in ICU - PARTNER","Virtual Reality in ICU (PARTNER) - A Research Study About Engaging in Strategies to Promote Relaxation, Improve Your Mood, and Stimulate Thinking in the Intensive Care Setting","VR-PARTNER","Inclusion Criteria:\n\n* Admitted to ICU at University of Kentucky for acute respiratory failure, sepsis or other\n\nExclusion Criteria:\n\n* Are less than 18 years of age\n* Have a pre-existing neurologic disorder\n* Have a pre-existing emotional or personality disorder\n* Have a history or active mental health disorder or disease\n* Experienced an acute neurologic event (e.g., stroke)\n* Are currently pregnant\n* Are a prisoner\n* Receiving hospice care\n* Have existing open wounds or pressure ulcers on head or neck","99 Years",{"count":57,"type":22},32,"This project is designed to have patients participate in a virtual environment with various tasks such as breathing exercises, games to help the brain, and techniques that promote relaxation while hospitalized in the Intensive Care Unit (ICU). The participation in research will last about 5 days and take about 15 to 45 minutes each day.",[60,61],"Acute Respiratory Failure","Sepsis",[63,64,65,66],"virtual reality","intensive care unit","sepsis","acute respiratory failure","2025-09-29",{"date":69,"type":39},"2025-10-03",{"date":71,"type":39},"2025-07-02",{"date":73,"type":22},"2026-09-30",{"name":45,"class":46},1,""]