[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Koç University\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":676},{"pageToken":4,"total":5,"offset":6,"count":7,"results":8},null,28,0,25,[9,47,77,106,134,165,194,220,249,274,303,337,358,389,409,438,465,485,505,532,553,575,598,625,651],{"id":10,"slug":11,"hasResults":12,"nctId":13,"briefTitle":14,"officialTitle":15,"acronym":16,"eligibilityCriteria":17,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":20,"enrollmentInfo":21,"targetDuration":4,"studyType":24,"phases":25,"briefSummary":27,"conditions":28,"keywords":31,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100644830","rectointercostal-plane-block-ricpb-for-laparoscopic-cholecystectomy-100644830",false,"NCT07676552","Rectointercostal Plane Block (RICPB) for Laparoscopic Cholecystectomy","Rectointercostal Plane Block (RICPB) for Postoperative Analgesia After Laparoscopic Cholecystectomy: A Randomized Controlled Trial","RICPB","Inclusion Criteria:\n\n* Age between 18 and 65 years\n* American Society of Anesthesiologists (ASA) physical status I-III\n* Scheduled for elective laparoscopic cholecystectomy\n* Body mass index (BMI) between 18 and 35 kg\u002Fm²\n* Ability to understand the study procedures and provide written informed consent\n\nExclusion Criteria:\n\n* Refusal to participate or inability to provide informed consent\n* Known allergy or hypersensitivity to local anesthetics, opioids, or study medications\n* Chronic opioid use or chronic pain syndrome\n* Coagulation disorders or ongoing anticoagulant therapy\n* Infection at the planned injection site\n* Pregnancy or breastfeeding\n* Cognitive impairment or inability to communicate pain scores\n* Severe hepatic, renal, cardiac, or respiratory disease judged by the investigator to interfere with study participation\n* Conversion from laparoscopic to open surgery\n* Previous upper abdominal surgery that may interfere with the block technique or pain assessment","ALL","18 Years","65 Years",{"count":22,"type":23},60,"ESTIMATED","INTERVENTIONAL",[26],"NA","This prospective randomized controlled trial is designed to evaluate the analgesic efficacy of ultrasound-guided rectointercostal plane block (RICPB) in patients undergoing elective laparoscopic cholecystectomy. Patients will be randomized to receive unilateral right-sided RICPB at the end of surgery. Postoperative opioid consumption, Numeric Rating Scale (NRS) pain scores, and postoperative complications will be assessed to determine the effectiveness of RICPB in postoperative pain management.",[29,30],"Cholelithiasis","Postoperative Pain",[32,33,16],"Laparoscopic Cholecystectomy","Rectointercostal Plane Block","NOT_YET_RECRUITING","2026-06-30",{"date":37,"type":38},"2026-07-02","ACTUAL",{"date":40,"type":23},"2026-07-01",{"date":42,"type":23},"2027-02-01",{"name":44,"class":45},"Koç University","OTHER",1,{"id":48,"slug":49,"hasResults":12,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":53,"eligibilityCriteria":54,"healthyVolunteers":12,"sex":18,"minAge":55,"maxAge":56,"enrollmentInfo":57,"targetDuration":4,"studyType":24,"phases":58,"briefSummary":59,"conditions":60,"keywords":64,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":71,"startDateStruct":73,"completionDateStruct":74,"leadSponsor":76,"locationsCount":4},"100640136","robotic-dog-intervention-on-emotional-well-being-and-quality-of-life-100640136","NCT07607379","Robotic Dog Intervention on Emotional Well-Being and Quality of Life","Effectiveness and Feasibility of a Robotic Dog Intervention on Emotional Well-Being and Quality of Life in Pediatric Patients With Hematological Malignancies Undergoing HSCT","ROBDOG","Inclusion Criteria:\n\n* Pediatric patients aged 8-15 years\n* Diagnosed with a hematological malignancy and undergoing hematopoietic stem cell transplantation\n* Hospitalized in a protective isolation room during the post-transplant inpatient period\n* Expected to remain hospitalized under isolation for approximately 30 days post-transplant\n* Able to understand and respond to Turkish-language self-report questionnaires\n* Clinically stable and deemed eligible for participation by the treating clinical team\n* Able to interact with the robotic dog at a basic functional level\n\nExclusion Criteria:\n\n* Severe cognitive impairment or neurodevelopmental conditions preventing meaningful interaction or self-report\n* Acute neurological conditions, delirium, or severe psychiatric crisis (e.g., acute agitation, suicidal ideation)\n* Requirement for intensive care, invasive ventilation, or a clinically unstable condition\n* Severe visual, hearing, or motor impairments that prevent interaction with the robotic dog\n* Additional infection control restrictions prevent the placement or use of the robotic dog in the isolation room\n* Anticipated early discharge, transfer, or inability to complete follow-up assessments\n* Severe fear, intolerance, or refusal to interact with robotic or electronic devices","8 Years","15 Years",{"count":5,"type":23},[26],"The hematopoietic stem cell transplantation (HSCT) process imposes a substantial psychological burden, leading to impaired emotional well-being due to intensive treatment, isolation, and immunosuppression. Patients often experience social withdrawal, loneliness, and loss of control, which may result in persistent anxiety, depressive symptoms, and reduced quality of life (QoL) if unaddressed. This study aims to evaluate the effectiveness, feasibility, and acceptability of an AI-powered robotic dog in improving emotional well-being and QoL in pediatric patients undergoing HSCT.",[61,62,63],"Emotional Well-being","Quality of Life","Pediatric Oncology",[65,66,67,68,69],"technology","pediatric oncohematology","Hematological Malignancy","well-being","nurse","2026-05-19",{"date":72,"type":38},"2026-05-26",{"date":40,"type":23},{"date":75,"type":23},"2028-06-30",{"name":44,"class":45},{"id":78,"slug":79,"hasResults":12,"nctId":80,"briefTitle":81,"officialTitle":82,"acronym":83,"eligibilityCriteria":84,"healthyVolunteers":12,"sex":18,"minAge":85,"maxAge":86,"enrollmentInfo":87,"targetDuration":4,"studyType":24,"phases":89,"briefSummary":90,"conditions":91,"keywords":94,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":99,"startDateStruct":101,"completionDateStruct":103,"leadSponsor":105,"locationsCount":4},"100640194","robo-paws-robot-dog-assisted-walking-100640194","NCT07603180","ROBO-PAWS: Robot-Dog-Assisted Walking","ROBO-PAWS: A Pilot Randomized Controlled Trial of Robot-Dog-Assisted Walking to Improve Sleep Quality, Fatigue, and Quality of Life in Pediatric Oncology Patients","ROBO-PAWS","Inclusion Criteria:\n\n* Aged between 2 and 7 years,\n* Diagnosed with cancer and currently receiving active treatment,\n* Pain level not severe enough to interfere with mobilization (FLACC or Wong-Baker FACES score ≤ 4),\n* Diagnosed within the previous 1 month,\n* Medically stable and approved by the physician to participate in light-intensity walking activities,\n* Expected to remain hospitalized for at least 1 month to allow completion of the study protocol,\n* Not scheduled for hematopoietic stem cell transplantation (HSCT) and not currently undergoing HSCT,\n* Hemoglobin level adequate for participation in walking activities (\\>10 g\u002FdL),\n* No significant impairment in consciousness, balance, or motor functions due to heavy analgesic or sedative medication use.\n\nExclusion Criteria:\n\n* Resting SpO₂ \\\u003C94%, requirement for ≥2 L\u002Fmin oxygen support, or recurrent desaturation episodes within the last 24 hours,\n* Heart rate or respiratory rate significantly elevated or irregular for age,\n* Hemodynamic instability,\n* Visual, hearing, or severe cognitive impairment that would prevent interaction with the robotic dog,\n* Increased mobilization risk due to high-dose corticosteroid treatment or medications associated with neurotoxicity,\n* Motor function limitations that would interfere with safe walking,\n* Concurrent severe infection or serious treatment-related complications (e.g., grade 3-4 mucositis or severe neutropenia requiring isolation),\n* Children receiving end-of-life care.","2 Years","7 Years",{"count":88,"type":23},40,[26],"Childhood cancers affect approximately 400,000 children and adolescents worldwide each year. Although advances in treatment have significantly improved survival rates, children undergoing cancer treatment continue to experience a wide range of treatment-related symptoms and complications. Among these, fatigue and sleep disturbances are particularly common and may persist throughout treatment and survivorship, negatively affecting psychological well-being, cognitive functioning, and overall quality of life. Reduced physical activity during treatment is strongly associated with worsening fatigue, impaired sleep, and decreased quality of life in pediatric oncology patients. However, treatment side effects, prolonged hospitalization, infection risk, and lack of motivating play-based activities often limit children's participation in physical activity during treatment. Recent evidence suggests that physical activity interventions may help reduce fatigue and improve well-being in children with cancer, yet engaging and age-appropriate non-pharmacological interventions remain limited, especially for younger children.\n\nThis pilot randomized controlled trial aims to evaluate the feasibility and potential effects of a robot-dog-assisted walking intervention on sleep quality, fatigue, and quality of life among children aged 2-7 years undergoing cancer treatment.",[92,93,62],"Sleep Quality","Fatigue",[95,96,97,98],"sleep quality","fatigue","children","cancer",{"date":100,"type":38},"2026-05-22",{"date":102,"type":23},"2026-06-01",{"date":104,"type":23},"2027-06-01",{"name":44,"class":45},{"id":107,"slug":108,"hasResults":12,"nctId":109,"briefTitle":110,"officialTitle":111,"acronym":4,"eligibilityCriteria":112,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":113,"targetDuration":4,"studyType":24,"phases":115,"briefSummary":116,"conditions":117,"keywords":122,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":127,"lastUpdatePostDateStruct":128,"startDateStruct":130,"completionDateStruct":131,"leadSponsor":133,"locationsCount":4},"100639797","psychosocial-effects-of-a-trauma-informed-artificial-intelligence-supported-chatbot-in-adults-newly-diagnosed-with-cancer-100639797","NCT07583069","Psychosocial Effects of a Trauma-Informed Artificial Intelligence-Supported Chatbot in Adults Newly Diagnosed With Cancer","Evaluation of the Psychosocial Effects of a Trauma-Informed Care-Based Artificial Intelligence-Supported Chatbot in Newly Diagnosed Cancer Patients: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Over 18 years of age,\n* Able to speak and understand Turkish,\n* Without any cognitive, visual, or auditory impairments,\n* Diagnosed with cancer within the last month (Stage I, II, and III) (regardless of cancer type),\n* Have started active cancer treatment,\n* Have access to a digital device and the internet,\n* Volunteer to participate in the study will be included.\n\nExclusion Criteria:\n\n* Patients participating in another simultaneous psychosocial\u002Fdigital intervention study,\n* Patients diagnosed with advanced stage (Stage IV) cancer, in the terminal phase and with metastases,\n* Patients diagnosed with schizophrenia, bipolar disorder, substance abuse, depression and anxiety disorders will be excluded.",{"count":114,"type":23},62,[26],"The goal of this clinical trial is to evaluate whether a trauma-informed, artificial intelligence-supported chatbot can reduce psychological distress and unmet psychosocial needs in adults newly diagnosed with cancer.:\n\n* Does the chatbot reduce trauma-related distress and anxiety levels compared to standard care?\n* Does the chatbot decrease unmet psychosocial needs in patients following a new cancer diagnosis? Researchers will compare the chatbot intervention to standard care to determine whether the chatbot provides additional psychosocial benefit.\n\nParticipants will:\n\n* Be randomly assigned to either the chatbot intervention group or the standard care group\n* Use the chatbot freely for 12 weeks (intervention group only)\n* Complete questionnaires at baseline, 1 month, and 3 months\n* Be monitored for any psychological risk indicators during the study period",[118,119,120,121],"Cancer","Psychosocial Distress","Trauma and Stress Related Disorders","Anxiety",[123,124,125,126],"cancer diagnosis","unmet psychosocial needs","trauma-informed care","AI-powered chatbot","2026-05-07",{"date":129,"type":38},"2026-05-13",{"date":40,"type":23},{"date":132,"type":23},"2027-01-01",{"name":44,"class":45},{"id":135,"slug":136,"hasResults":12,"nctId":137,"briefTitle":138,"officialTitle":139,"acronym":140,"eligibilityCriteria":141,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":142,"targetDuration":4,"studyType":144,"phases":4,"briefSummary":145,"conditions":146,"keywords":151,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":158,"lastUpdatePostDateStruct":159,"startDateStruct":161,"completionDateStruct":162,"leadSponsor":164,"locationsCount":46},"100636053","barrier-functions-of-skin-in-icu-skin-bar-100636053","NCT07560683","Barrier Functions oF Skin in ICU: SKIN-BAR","Investigation of Skin Barrier Function Using Biosensor Methods in Risky Skin Regions and Developed Pressure Injuries in Intensive Care Patients, and Identification of Influencing Factors: The SKIN-BAR Project","SKIN-BAR","Inclusion Criteria:\n\n* Adults aged \\>18 years\n* Admission to the intensive care unit\n* Initial skin assessment completed within the first 4 hours after ICU admission\n* Hemodynamically stable enough to undergo follow-up and repeated skin measurements\n* Intact skin integrity at ICU admission\n* Willingness to participate in the study, with informed consent provided by the participant or legally authorized representative\n\nExclusion Criteria:\n\n* Inability to tolerate position changes\n* Post-cardiopulmonary resuscitation care period at enrollment\n* Cardiac arrest or cardiopulmonary resuscitation during follow-up\n* Severe edema or subcutaneous fluid accumulation\n* Presence of skin lesions before ICU admission\n* Systemic dermatologic disease directly affecting skin barrier function",{"count":143,"type":23},156,"OBSERVATIONAL","This study aims to investigate skin barrier function in intensive care unit (ICU) patients using biosensor-based measurements. Biophysical parameters including transepidermal water loss (TEWL), skin pH, stratum corneum hydration, local skin temperature, and sebum will be assessed in anatomical regions at risk for pressure injuries. The study will examine temporal changes in these parameters, their interrelationships, and their association with pressure injury development.",[147,148,149,150],"Pressure Injuries","Skin Failure","Skin Abnormalities","Biophysical Parameters of Skin",[152,153,154,155,156,157],"barrier function of skin","pressure-prone skin areas","pressure injury","intensive care unit","biosensory","skin integrity","2026-04-28",{"date":160,"type":38},"2026-05-01",{"date":40,"type":23},{"date":163,"type":23},"2028-10-01",{"name":44,"class":45},{"id":166,"slug":167,"hasResults":12,"nctId":168,"briefTitle":169,"officialTitle":170,"acronym":171,"eligibilityCriteria":172,"healthyVolunteers":173,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":174,"targetDuration":4,"studyType":24,"phases":176,"briefSummary":177,"conditions":178,"keywords":181,"overallStatus":186,"whyStopped":4,"lastUpdateSubmitDate":187,"lastUpdatePostDateStruct":188,"startDateStruct":190,"completionDateStruct":192,"leadSponsor":193,"locationsCount":46},"100633614","effect-of-peer-education-on-climate-change-awareness-and-anxiety-in-nursing-students-100633614","NCT07528976","Effect of Peer Education on Climate Change Awareness and Anxiety in Nursing Students","The Effect of Peer Education on Climate Change Awareness and Anxiety in Nursing Students: A Quasi-Experimental Study","PEER-CLIMATE","Inclusion Criteria:\n\nBeing a nursing student at the Faculty of Health Sciences Being enrolled at Istanbul Aydin University Voluntarily agreeing to participate in the study Providing informed consent\n\nExclusion Criteria:\n\nBeing a student outside the nursing department or a guest student Not providing informed consent Submitting incomplete questionnaires (≥20% missing responses)",true,{"count":175,"type":23},65,[26],"This study aims to evaluate the effect of peer education on climate change awareness and climate change anxiety levels among nursing students at the Faculty of Health Sciences, Istanbul Aydin University.\n\nWithin the scope of the study, changes in students' awareness and anxiety levels before and after the peer education intervention will be assessed.\n\nThe study is expected to contribute to improving nursing students' knowledge and awareness regarding the health impacts of climate change and to support the integration of sustainability and environmental health into nursing education.",[179,180],"Climate Change Awareness","Climate Change Anxiety",[182,183,184,185],"Climate Change","Eco-Anxiety","Peer Education","Nursing Students","RECRUITING","2026-04-07",{"date":189,"type":38},"2026-04-14",{"date":191,"type":38},"2026-04-06",{"date":102,"type":23},{"name":44,"class":45},{"id":195,"slug":196,"hasResults":12,"nctId":197,"briefTitle":198,"officialTitle":199,"acronym":4,"eligibilityCriteria":200,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":201,"enrollmentInfo":202,"targetDuration":4,"studyType":24,"phases":203,"briefSummary":204,"conditions":205,"keywords":207,"overallStatus":186,"whyStopped":4,"lastUpdateSubmitDate":213,"lastUpdatePostDateStruct":214,"startDateStruct":216,"completionDateStruct":218,"leadSponsor":219,"locationsCount":46},"100629547","evaluation-of-the-effect-of-digital-based-games-on-the-visual-and-cognitive-performance-of-young-children-with-intellectual-disabilities-100629547","NCT07476092","Evaluation of the Effect of Digital-based Games on the Visual and Cognitive Performance of Young Children With Intellectual Disabilities","Evaluation of the Effect of Digital-based Games on the Visual and Cognitive Performance of Young Children With Intellectual Disabilities: A Randomized Controlled Study","Inclusion Criteria:\n\n* Individuals aged 18-35 years\n* Diagnosed with mild or moderate intellectual disability\n* Receiving services from EÇADEM\n* Ability to participate in cognitive activities\n* Written consent from parents\u002Fguardians\n* No visual or hearing impairment\n* No severe motor coordination problems\n\nExclusion Criteria:\n\n* Severe intellectual disability\n* Visual or hearing impairment\n* Any medical condition preventing participation\n* Lack of participant or parental consent","35 Years",{"count":22,"type":23},[26],"This randomized controlled trial aims to evaluate the effect of digital intelligence games on visual and cognitive performance in young individuals with intellectual disabilities. Participants aged 18-35 years receiving services from EÇADEM in Istanbul will be randomly assigned to either an intervention group receiving digital intelligence game training using the MentalUP application or a control group receiving routine services. Visual memory and cognitive performance will be assessed using the Benton Visual Retention Test and the Standardized Mini Mental Test at baseline, 3 months, 6 months, and 12 months. The study will investigate the short- and long-term effects of digital cognitive training on visual and cognitive functioning.",[206],"Intellectual Disability",[206,208,209,210,211,212],"Cognitive Performance","Visual Memory","Digital Intelligence Games","Randomized Controlled Trial","MentalUP","2026-03-16",{"date":215,"type":38},"2026-03-18",{"date":217,"type":38},"2025-06-01",{"date":102,"type":23},{"name":44,"class":45},{"id":221,"slug":222,"hasResults":12,"nctId":223,"briefTitle":224,"officialTitle":225,"acronym":226,"eligibilityCriteria":227,"healthyVolunteers":12,"sex":228,"minAge":19,"maxAge":4,"enrollmentInfo":229,"targetDuration":4,"studyType":24,"phases":231,"briefSummary":232,"conditions":233,"keywords":238,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":241,"lastUpdatePostDateStruct":242,"startDateStruct":244,"completionDateStruct":246,"leadSponsor":248,"locationsCount":4},"100627213","effect-of-guided-imagery-and-ai-assisted-video-on-pain-during-uterine-involution-assessment-in-postpartum-women-a-randomized-controlled-trial-100627213","NCT07445711","Effect of Guided Imagery and AI-Assisted Video on Pain During Uterine Involution Assessment in Postpartum Women: A Randomized Controlled Trial","The Effect of Guided Imagery and Artificial Intelligence-Assisted Video on Pain During Uterine Involution Assessment in Postpartum Women: A Randomized Controlled Trial","GAIUTERUSRCT","Inclusion Criteria:\n\n* Age: Postpartum women aged 18 years and older.\n* Obstetric History: Primiparous women who have had a vaginal delivery.\n* Procedure: Presence of an episiotomy during vaginal delivery.\n* Physical Condition: Absence of physical conditions (e.g., postpartum hemorrhage, risk of sepsis) that would interfere with the safe assessment of uterine involution or the implementation of interventions.\n* Technological Competence: Ability to participate in guided imagery and AI-powered video interventions, including the seamless use of digital equipment such as headphones and goggles.\n* Consent: Voluntarily agreeing to participate and signing the informed consent form.\n\nExclusion Criteria:\n\n* Medication: Use of analgesic or opioid medications within the last 4-6 hours.\n* Mental Health: History of or current mental health disorders, such as anxiety or depression.\n* Medical Urgency: Requiring intensive care treatment or experiencing medical emergencies during hospitalization.\n* Neonatal Status: Having a newborn admitted to the Neonatal Intensive Care Unit (NICU).\n* Chronic Illness: Diagnosis of any chronic disease.\n* Study Continuity: Inability to continue the study for any reason (e.g., withdrawal due to medical emergencies).\n* Psychological History: Having received or currently receiving psychotherapy or psychological interventions.\n* Communication Barriers: Language barriers or communication difficulties that prevent the accurate application of research tools.\n* Sensory Impairments: Presence of visual or auditory impairments.","FEMALE",{"count":230,"type":23},150,[26],"Uterine involution, the process by which the uterus returns to its pre-pregnancy size during the postpartum period, can cause severe cramp-like pain in postpartum women. Although pharmacological methods are common for managing this pain in the literature, their side effects limit their use in this population. This project aims to fill a significant gap in the literature by combining guided imagery, a non-pharmacological technique, with evolving artificial intelligence (AI) technologies. While the effectiveness of guided imagery in cesarean and labor pain is well-known, its impact on pain and physiological parameters during uterine involution-specifically through AI-supported visualization-will be evaluated for the first time within the scope of this study. The primary research question of the project is: \"Do guided imagery and AI-supported video applications have a healing effect on the pain levels and vital signs of postpartum women during the evaluation of uterine involution?\" This research is a three-arm, randomized controlled experimental study to be conducted at Istanbul Atlas University Hospital. The sample size of the study was determined using the G\\*Power 3.1 program. As a result of the a priori power analysis performed by selecting the \"ANOVA: Fixed effects, omnibus, one-way\" statistical test under the \"F tests\" family, the significance level was set at α = 0.05, the statistical power (1-β) at 0.80, and the effect size (f) at 0.25 (medium effect). The analysis indicated a total sample size of 159 participants for the three groups, with 53 participants required in each group. To account for potential sample attrition, a 10% addition was made to each group, resulting in a planned study with 59 participants per group and a total of 177 participants. \"Guided Imagery\" and \"AI-Supported Video\" applications will be utilized as intervention methods. In the guided imagery group, an expert-approved original audio script titled \"The Emotional Journey of Mother and Baby\" will be played to the women via over-ear headphones during the uterine involution assessment. In the AI-supported video group, a video generated with AI prompts based on the same script will be shown using virtual reality (VR) goggles during the assessment. This will allow for a comparative analysis of the effects of visual and auditory stimuli on pain during the uterine involution evaluation. Participants' pain levels will be measured using the VAS scale, and physiological data (pulse, blood pressure, SpO₂) will be recorded by monitoring at the 60th, 120th, and 180th seconds of the involution process. Considering the moderating effect of anxiety on pain threshold and vital signs, the 'Postpartum Specific Anxiety Scale' will be administered to all participants before the intervention. Data will be analyzed using ANOVA and Kruskal-Wallis tests in the SPSS 23 program.",[234,235,236,237],"Uterine Involution","Guided Imagery","Artificial Intelligence (AI)","Postpartum Women",[239,235,240,237,234],"Artificial Intelligence","Pain","2026-02-25",{"date":243,"type":38},"2026-03-03",{"date":245,"type":23},"2026-02-28",{"date":247,"type":23},"2026-12-31",{"name":44,"class":45},{"id":250,"slug":251,"hasResults":12,"nctId":252,"briefTitle":253,"officialTitle":253,"acronym":4,"eligibilityCriteria":254,"healthyVolunteers":12,"sex":18,"minAge":4,"maxAge":4,"enrollmentInfo":255,"targetDuration":4,"studyType":144,"phases":4,"briefSummary":257,"conditions":258,"keywords":260,"overallStatus":186,"whyStopped":4,"lastUpdateSubmitDate":266,"lastUpdatePostDateStruct":267,"startDateStruct":269,"completionDateStruct":271,"leadSponsor":273,"locationsCount":46},"100624452","a-novel-classification-in-calcific-tendinitis-of-the-shoulder-evaluating-mri-localization-and-related-treatment-strategies-100624452","NCT07409818","A Novel Classification in Calcific Tendinitis of the Shoulder: Evaluating MRI Localization and Related Treatment Strategies","Inclusion Criteria\n\n* Patients who underwent surgical treatment for calcific tendinitis\n* Presence of single or multiple calcific deposits within the rotator cuff tendons\n\nExclusion Criteria\n\n* History of prior ipsilateral shoulder surgery for indications other than calcific tendinitis\n* Revision surgery for calcific tendinitis\n* Incomplete clinical documentation or unavailable MRI data",{"count":256,"type":23},400,"Calcific tendinitis of the shoulder is among the frequently encountered shoulder problems. Conservative treatment is often preferred for its management. Persistent pain, impingement symptoms due to large calcific deposits, and extension into the bone are indications for surgical intervention.\n\nAlthough many classification methods for calcific tendinitis have been defined in the literature, none of them is directly related to prognosis, treatment options, or surgical management.\n\nThe aim of this study is to create a new, easy-to-apply, practical, and treatment-related classification system for calcific tendinitis based on the localization of the deposits on MRI.\n\nFurthermore, the aim is to compile the current patient cohort according to this new classification and examine the relationship between the treatment applied and the deposit localization in the proposed classification.",[259],"Calcific Tendinitis of Shoulder",[261,262,263,264,265],"calcific tendinitis","shoulder","magnetic resonance imaging","calcific deposit","novel classification","2026-02-06",{"date":268,"type":38},"2026-02-13",{"date":270,"type":38},"2025-10-02",{"date":272,"type":23},"2026-10-02",{"name":44,"class":45},{"id":275,"slug":276,"hasResults":12,"nctId":277,"briefTitle":278,"officialTitle":278,"acronym":4,"eligibilityCriteria":279,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":280,"enrollmentInfo":281,"targetDuration":4,"studyType":24,"phases":283,"briefSummary":284,"conditions":285,"keywords":291,"overallStatus":186,"whyStopped":4,"lastUpdateSubmitDate":296,"lastUpdatePostDateStruct":297,"startDateStruct":299,"completionDateStruct":301,"leadSponsor":302,"locationsCount":46},"100623447","the-effects-of-transversalis-fascia-plane-block-on-opioid-consumption-in-patients-undergoing-hand-assisted-laparoscopic-donor-nephrectomy-a-randomized-controlled-prospective-study-100623447","NCT07396753","The Effects of Transversalis Fascia Plane Block on Opioid Consumption in Patients Undergoing Hand-Assisted Laparoscopic Donor Nephrectomy: A Randomized Controlled Prospective Study","Inclusion Criteria:\n\n* Approved by the transplant committee for living kidney donation\n* Scheduled for hand-assisted laparoscopic donor nephrectomy (HALDN)\n* Able to understand study procedures and provide written informed consent\n\nExclusion Criteria:\n\n* Known allergy to any medications used in the study (e.g., local anesthetics, opioids)\n* Chronic opioid use or use of opioid receptor agonists\n* Inability to communicate effectively (e.g., cognitive impairment, language barrier)\n* Chronic organ failure or major organ dysfunction\n* Refusal or inability to provide informed consent\n* Foreign nationality (if follow-up or consent is restricted)\n* American Society of Anesthesiologists (ASA) physical status ≥ III","80 Years",{"count":282,"type":23},50,[26],"This study aims to evaluate whether a regional anesthesia technique called the transversalis fascia plane block (TFPB) can improve pain control after hand-assisted laparoscopic donor nephrectomy (HALDN), a minimally invasive surgery performed in living kidney donors.\n\nAlthough HALDN is less invasive than open surgery, patients often experience significant pain after the operation, mainly due to the surgical incisions in the lower abdomen and trocar entry sites. Poorly controlled pain can delay recovery and increase the need for opioid pain medications, which may cause side effects such as nausea, vomiting, itching, and sedation.\n\nThe transversalis fascia plane block is an ultrasound-guided regional anesthesia technique in which a local anesthetic is injected into a specific tissue plane in the lower abdominal wall. This injection temporarily blocks pain signals from nerves supplying the lower abdomen and groin area. The technique has been shown to reduce pain and opioid use after various lower abdominal surgeries and is considered minimally invasive and safe when performed under ultrasound guidance.\n\nIn this study, patients undergoing HALDN will be randomly assigned to one of two groups. One group will receive standard general anesthesia only, while the other group will receive general anesthesia plus a transversalis fascia plane block using a local anesthetic (bupivacaine). All patients will receive the same standard pain treatment after surgery, including paracetamol and patient-controlled morphine.\n\nThe main goal of the study is to compare the amount of opioid pain medication used during the first 24 hours after surgery between the two groups. Secondary outcomes include pain scores measured using the Numeric Rating Scale (NRS), the frequency of opioid-related side effects, and patient satisfaction with pain control.\n\nThe results of this study may help determine whether adding the transversalis fascia plane block to standard anesthesia can provide better pain relief, reduce opioid consumption, and improve comfort and recovery in living kidney donors.",[30,286,287,288,289,290],"Analgesics, Opioid","Pain Management","Anesthesia Regional","Living Donors","Nephrectomy,Kidney Donation",[292,293,294,295],"Hand-assisted laparoscopic donor nephrectomy","Transversalis fascia plane block","Regional anesthesia","Opioid consumption","2026-02-02",{"date":298,"type":38},"2026-02-09",{"date":300,"type":38},"2025-07-25",{"date":243,"type":23},{"name":44,"class":45},{"id":304,"slug":305,"hasResults":12,"nctId":306,"briefTitle":307,"officialTitle":308,"acronym":309,"eligibilityCriteria":310,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":311,"enrollmentInfo":312,"targetDuration":4,"studyType":24,"phases":314,"briefSummary":315,"conditions":316,"keywords":321,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":329,"lastUpdatePostDateStruct":330,"startDateStruct":332,"completionDateStruct":334,"leadSponsor":336,"locationsCount":46},"100611476","whatsapp-based-and-family-involved-diabetes-self-management-education-study-100611476","NCT07241078","WhatsApp-Based and Family-Involved Diabetes Self-Management Education Study","The Effect of WhatsApp-Based and Family-Involved Self-Management Education and Support on HbA1c, Family Support, and Self-Management in Individuals With Type 2 Diabetes","WAF-DSMES","Inclusion Criteria: People diagnosed with type 2 diabetes at least six months prior, receiving insulin and\u002For oral antidiabetic therapy, with an HbA1c value of 7% or higher, capable of communicating in Turkish, literate, and possessing the ability to use a smartphone and WhatsApp, as well as having internet access. Participants are required to agree to participate together with a family member who can provide support related to diabetes. Family members involved in the intervention are expected to be able to communicate in Turkish, literate, able to use a smartphone and WhatsApp, have internet access, and reside within reach of the participant with diabetes.\n\n\\-\n\nExclusion Criteria: Individuals will be excluded if they have type 1 diabetes or gestational diabetes, severe cognitive impairment, advanced visual or hearing loss, any condition preventing the use of digital platforms, or communication or language barriers that would hinder participation. Family members will be excluded if they have diabetes, cognitive impairment, advanced visual or hearing loss, inability to use digital tools, or communication and language barriers.\n\n\\-","74 Years",{"count":313,"type":23},88,[26],"The aim of this study is to evaluate the effects of a WhatsApp-based and family-involved self-management education program on self-management, family support, and HbA1c levels among individuals with type 2 diabetes mellitus (T2DM).\n\nHypotheses:\n\n* H1: There will be a significant difference in self-management scores between the intervention group receiving the WhatsApp-based and family-involved self-management education and the control group.\n* H2: There will be a significant difference in HbA1c levels between the intervention group receiving the WhatsApp-based and family-involved self-management education and the control group.\n* H3: There will be a significant difference in family support scores between the intervention group receiving the WhatsApp-based and family-involved self-management education and the control group.\n\nThis randomized controlled trial will be conducted with 44 individuals diagnosed with T2DM who meet the inclusion criteria and one family member per participant (total 88 participants). Eligible patients will be randomly assigned to either the intervention or control group using a computer-generated randomization list.\n\nParticipants (people with diabetes and their family members) in the intervention group will receive a 12-week, WhatsApp-based self-management education program. Educational modules (videos, visuals, and written materials) will be shared separately with each person with diabetes and their participating family member via WhatsApp twice a week. To reinforce learning, a five-question quiz will be sent separately to both the person with diabetes and the family member every Thursday. In addition, a brief follow-up phone call (approximately 10 minutes) will be conducted once a week only with the person with diabetes to review progress and provide feedback. Data collection will occur at baseline and at the end of the 12th week.\n\nParticipants in the control group will continue their routine outpatient follow-ups for three months and complete the same measurement tools at baseline and post-intervention.\n\nData will be collected using the Diabetic Participant Demographic Form, Family Member Demographic Form, Diabetes Self Management Questionnaire, Hensarling's Diabetes Family Support Scale, and the Diabetes Knowledge Scale for Adults. Statistical analyses will be performed using SPSS software. Group comparisons will be analyzed with independent t-tests or Mann-Whitney U tests, and pre-post comparisons with paired t-tests or Wilcoxon tests. A significance level of p\\\u003C0.05 will be used.",[317,318,319,320],"Diabetes Mellitus, Type 2","Diabete Mellitus","Diabetes Education","Self-management",[322,323,324,325,326,327,328],"diabetes","family involved","WhatsApp based","family support","HbA1c","self management","type 2 diabetes","2025-11-16",{"date":331,"type":38},"2025-11-21",{"date":333,"type":23},"2025-11",{"date":335,"type":23},"2026-11",{"name":44,"class":45},{"id":338,"slug":339,"hasResults":12,"nctId":340,"briefTitle":341,"officialTitle":341,"acronym":4,"eligibilityCriteria":342,"healthyVolunteers":12,"sex":343,"minAge":19,"maxAge":4,"enrollmentInfo":344,"targetDuration":4,"studyType":24,"phases":346,"briefSummary":347,"conditions":348,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":350,"lastUpdatePostDateStruct":351,"startDateStruct":353,"completionDateStruct":355,"leadSponsor":357,"locationsCount":4},"100605431","the-effect-of-art-therapy-on-disease-severity-and-anxiety-levels-in-inpatients-at-a-psychiatry-clinic-100605431","NCT07162428","The Effect of Art Therapy on Disease Severity and Anxiety Levels in Inpatients at a Psychiatry Clinic","Inclusion Criteria:\n\nAge 18 years or older.\n\nCurrently hospitalized in the psychiatry clinic and expected to remain hospitalized during the study period.\n\nNo medical condition such as intellectual disability or organic mental disorder that would interfere with the administration of scales and tests.\n\nA PANSS score of ≤62 (since a score of 61 is considered the remission criterion in schizophrenia, patients scoring 62 or below will be included).\n\nA score between 5-18 on the Young Mania Rating Scale.\n\nReceiving treatment in the clinic for at least 3 days.\n\nProviding verbal and\u002For written informed consent to participate in the study.\n\nExclusion Criteria:\n\nBeing in an acute psychotic episode or having severe psychotic symptoms (e.g., severe delusions, hallucinations) making the patient unsuitable for group participation.\n\nClinical conditions involving excessive agitation or homicidal risk that make group participation inappropriate.\n\nInability to actively participate in art therapy due to visual, hearing, or severe motor impairments.\n\nPatients for whom discharge is planned during the clinical course (e.g., those scheduled for discharge in less than 3 days).\n\nDiagnosis of an organic mental disorder (e.g., dementia, delirium).\n\nSevere physical illness or motor impairment preventing participation in group activities","MALE",{"count":345,"type":23},48,[26],"The aim of this study is to examine the effect of art therapy applied to inpatients in the psychiatry ward on disease severity and anxiety levels. Art therapy is considered a complementary intervention that can positively contribute to the psychiatric recovery process by facilitating the expression and regulation of an individual's emotional state.\n\nThis research will be conducted with a randomized controlled design and aims to demonstrate the effectiveness of art therapy practices within the clinical process through objective data. The originality of the study lies in the fact that art therapy will be implemented with individuals hospitalized in an acute psychiatric ward. In this respect, the study provides the opportunity to evaluate the applicability of art therapy even during crisis periods and carries the potential to make significant practice-oriented contributions to the field of mental health.",[349],"Psychiatric Disorders","2025-09-17",{"date":352,"type":38},"2025-09-23",{"date":354,"type":23},"2025-09-15",{"date":356,"type":23},"2025-11-01",{"name":44,"class":45},{"id":359,"slug":360,"hasResults":12,"nctId":361,"briefTitle":362,"officialTitle":363,"acronym":364,"eligibilityCriteria":365,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":366,"targetDuration":4,"studyType":24,"phases":368,"briefSummary":369,"conditions":370,"keywords":377,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":383,"lastUpdatePostDateStruct":384,"startDateStruct":385,"completionDateStruct":386,"leadSponsor":388,"locationsCount":46},"100606160","effects-of-artificial-intelligence-nurse-orientation-program-on-psychological-outcomes-and-length-of-hospital-stay-in-intensive-care-unit-100606160","NCT07171944","Effects of Artificial Intelligence Nurse Orientation Program on Psychological Outcomes and Length of Hospital Stay in Intensive Care Unit","Effects of AINurse Orientation Program on Psychological Outcomes and Length of Hospital Stay: A Randomized Controlled Trial","AINURSE-OP","Inclusion Criteria:\n\n* Intensive care unit confusion assessment scale (CAM-ICU scale) score of 0-2\n* Age 18 years or older\n* Hospitalized in the intensive care unit for at least 24 hours\n* Glasgow coma scale score of 13-14-15 points\n* Richmond Agitation Sedation Scale (RASS) score between -1 and +1\n* No hearing problems\n\nExclusion Criteria:\n\n* Intensive care unit confusion assessment scale (CAM-ICU scale) score of 6-7\n* Any psychiatric illness or impaired brain function\n* Defined hearing loss\n* Advanced dementia\n* Younger than 18 years of age\n* Richmond Agitation Sedation Scale (RASS) score outside the range of -1 to +1\n* Who use sedative medication\n* History of surgery or disease around the ear",{"count":367,"type":23},10,[26],"Artificial intelligence (AI), now an integral part of healthcare services and presents numerous opportunities. Customized treatment plans, clinical decision support systems, predictive analysis for disease prevention, patient engagement and education, quality improvement, and error reduction are some of these opportunities. In the context of delirium prevention, risk assessment, and treatment planning, the AI-supported system AI-AntiDelirium is designed to standardize the approach to delirium management in alignment with the PADIS guidelines. A randomized controlled trial evaluating the effectiveness of this system found that the workload of nurses decreased, facilitated early diagnosis and prevention of delirium, and recommended evidence-based and individualized delirium interventions. A systematic review concluded that AI applications did not significantly impact the length of hospital stay and emphasized the need for further research. Also, AI platforms contributed to positive results in reducing anxiety and depression in patients. Furthermore, systematic reviews have demonstrated that AI-based chatbots are effective in alleviating symptoms of depression and anxiety. However, the literature includes a limited number of patient education programs specifically designed to prevent or manage delirium through AI-based approaches. Notably, there is a lack of studies comparing the effectiveness of AI-supported educational interventions with those delivered directly by nurses.\n\nThe goal of this clinical trial is to develop a structured AINurse and Human Nurse orientation training program for intensive care unit (ICU) patients and compare the effects of these training programs on ICU patients' delirium-free days, level of anxiety and depression, and length of stay in the ICU. Hypotheses of the study:\n\nH1: Patients who receive the structured AINurse patient orientation training program will have longer delirium-free days than patients who receive Human Nurse orientation training.\n\nH2: Patients who receive the structured AINurse patient orientation training program will have lower levels of anxiety and depression than patients who receive the Human Nurse orientation training.\n\nH3: Patients who receive the structured AINurse patient orientation training program will have shorter lengths of stay in the intensive care unit than patients who receive the Human Nurse orientation training.\n\nResearchers will compare the AINurse patient orientation training program and the orientation training program provided by human nurses in terms of patients' delirium-free days, level of anxiety and depression, and length of stay in the ICU.\n\n* Those in the intervention group will receive the AINurse orientation training program twice daily for 3 days.\n* Participants in the control group will receive face-to-face structured orientation training from researchers twice daily for 3 days.\n* Delirium-free day assessment, anxiety and depression will be evaluated for patients in both groups over 3 days.\n* The length of stay in the intensive care unit will be monitored for patients in both groups.",[371,372,373,236,374,375,376],"Delirium","Anxiety and Depression","Intensive Care Units (ICUs)","Nurse","Critical Care","Orientation",[371,378,379,380,381,382,374],"Artificial intelligence","Anxiety and depression","Intensive care unit","critical care","Orientation Training","2025-09-10",{"date":354,"type":38},{"date":356,"type":23},{"date":387,"type":23},"2026-11-01",{"name":44,"class":45},{"id":390,"slug":391,"hasResults":12,"nctId":392,"briefTitle":393,"officialTitle":394,"acronym":4,"eligibilityCriteria":395,"healthyVolunteers":173,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":396,"targetDuration":4,"studyType":144,"phases":4,"briefSummary":397,"conditions":398,"keywords":4,"overallStatus":186,"whyStopped":4,"lastUpdateSubmitDate":400,"lastUpdatePostDateStruct":401,"startDateStruct":403,"completionDateStruct":405,"leadSponsor":407,"locationsCount":408},"100589648","vista-protein-expression-of-monocyte-and-t-cell-subsets-in-multiple-sclerosis-and-its-clinical-correlation-100589648","NCT06957145","Vista Protein Expression of Monocyte and T Cell Subsets in Multiple Sclerosis and Its Clinical Correlation","Vista Protein Expression of Monocyte and T Cell Subsets in Multiple Sclerosis and Its Clinical Correlation: A 1-Year Follow-up Study","Inclusion Criteria:\n\n* Patients aged 18 years or older diagnosed with MS or CIS according to the 2017 McDonald criteria.\n* No diagnosis of any autoimmune disease or malignancy.\n* No new diagnosis of autoimmune disease or malignancy during the 1-year follow-up period.\n* No use of antibiotics, nonsteroidal anti-inflammatory drugs (NSAIDs), or steroid treatments within one month prior to blood sampling.\n* No vaccination within one month prior to blood sampling.\n* Not in the menstrual cycle at the time of blood sampling.\n\nExclusion Criteria:\n\n* Age below 18 years.\n* Presence of a previous or newly diagnosed autoimmune disease or malignancy at the time of blood sampling.\n* Use of antibiotics, nonsteroidal anti-inflammatory drugs (NSAIDs), or steroid treatments within one month prior to blood sampling.\n* Vaccination within one month prior to blood sampling\n* Being in the menstrual cycle at the time of blood sampling\n* Patients without a definitive MS diagnosis according to the 2017 McDonald criteria will not be included in the study.",{"count":22,"type":23},"The aim of this study is to investigate whether VISTA, a newly identified negative immune regulatory protein, differs in monocytes and T cells of patients diagnosed with Multiple Sclerosis (MS) and Clinically Isolated Syndrome (CIS) compared to the same cell types in healthy controls. Additionally, the potential clinical correlation of VISTA expression in the follow-up of MS and CIS patients will be examined. By elucidating the role of VISTA in the pathophysiology of MS, this study will contribute to the literature by exploring its potential as a biomarker and its relevance in the development of novel therapeutic strategies.\n\nSpecifically, this study will compare VISTA protein secretion in MS patients at the time of their first attack with that of healthy controls. Furthermore, changes in VISTA protein secretion will be assessed in blood samples collected at 6- and 12-month follow-ups, and the correlations of these changes with clinical and laboratory findings will be investigated.\n\nFinally, this study aims to determine whether CD4+ and CD8+ T cells, monocytes, and T regulatory (Treg) subgroups in the first attack blood samples of MS patients exhibit similar functional properties in terms of VISTA protein secretion as their counterparts in healthy controls. To achieve this, monocytes and T cell subtypes will be stimulated, and their pro- and anti-inflammatory cytokine responses will be analyzed.",[399],"Multiple Sclerosis, MS","2025-08-30",{"date":402,"type":38},"2025-09-03",{"date":404,"type":38},"2025-06-30",{"date":406,"type":23},"2026-12-30",{"name":44,"class":45},2,{"id":410,"slug":411,"hasResults":12,"nctId":412,"briefTitle":413,"officialTitle":414,"acronym":415,"eligibilityCriteria":416,"healthyVolunteers":173,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":417,"targetDuration":4,"studyType":24,"phases":419,"briefSummary":420,"conditions":421,"keywords":427,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":431,"lastUpdatePostDateStruct":432,"startDateStruct":434,"completionDateStruct":435,"leadSponsor":437,"locationsCount":4},"100598654","training-program-for-peg-caregivers-a-structured-intervention-study-100598654","NCT07074301","Training Program for PEG Caregivers: A Structured Intervention Study","Effectiveness of Education and Mobile Application for Percutaneous Endoscopic Gastrostomy Care","PEG-EDU","Inclusion Criteria:\n\n* Age 18 or older\n* Willingness to participate voluntarily in the study\n* No communication barriers\n* Ability to use a smartphone\n* No diagnosed psychiatric disorder\n* Providing care to a patient aged 18 or older who is scheduled to undergo PEG placement\n\nExclusion Criteria:\n\n* Discharge from hospital or death of the patient during the study period\n* Being under 18 years old\n* Illiteracy of the caregiver",{"count":418,"type":23},80,[26],"This study aims to develop and evaluate a structured education program and a mobile application to support caregivers of patients receiving enteral nutrition via percutaneous endoscopic gastrostomy (PEG). The intervention focuses on improving caregivers' knowledge, care practices, and perceived burden. The study will be conducted in three phases: a needs assessment, development of the education and digital support modules, and implementation of the intervention. Quantitative and qualitative data will be collected to evaluate the impact of the intervention. The results are expected to contribute to the improvement of home PEG care quality and the empowerment of caregivers.",[422,423,424,425,426],"Percutaneous Endoscopic Gastrostomy (PEG)","Training","Caregiver Burden","Nutritional Support","Training Effectiveness",[428,424,429,430],"Percutaneous endoscopic gastrostomy","Structured Training","Home Enteral Nutrition","2025-08-29",{"date":433,"type":38},"2025-09-05",{"date":433,"type":23},{"date":436,"type":23},"2026-03-31",{"name":44,"class":45},{"id":439,"slug":440,"hasResults":12,"nctId":441,"briefTitle":442,"officialTitle":443,"acronym":4,"eligibilityCriteria":444,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":445,"targetDuration":4,"studyType":144,"phases":4,"briefSummary":447,"conditions":448,"keywords":450,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":457,"lastUpdatePostDateStruct":458,"startDateStruct":460,"completionDateStruct":462,"leadSponsor":464,"locationsCount":4},"100601223","blood-pressure-monitoring-accuracy-in-patients-undergoing-lung-surgery-with-one-lung-ventilation-using-an-arm-cuff-and-arterial-line-100601223","NCT07107698","Blood Pressure Monitoring Accuracy in Patients Undergoing Lung Surgery With One-Lung Ventilation Using an Arm Cuff and Arterial Line","Accuracy of Non-Invasive Blood Pressure Monitoring During Video-Assisted Thoracoscopic Surgery With One-Lung Ventilation: A Prospective Error Grid Analysis","Inclusion Criteria:\n\n* Age 18 years or older\n* Scheduled to undergo video-assisted thoracoscopic surgery with one-lung ventilation\n* Will receive invasive arterial blood pressure monitoring as part of routine clinical care\n\nExclusion Criteria:\n\n* Has peripheral artery disease\n* Has congestive heart failure",{"count":446,"type":23},90,"This study will test how accurate a blood pressure cuff is during a specific type of chest surgery.\n\nIn some lung surgeries, doctors use a method called video-assisted thoracoscopic surgery (VATS), where small tools and a camera are inserted through the chest wall. During these procedures, patients often have only one lung ventilated to give the surgeon more space to work. This setup can affect how well a blood pressure cuff on the arm reflects the true blood pressure inside the body.\n\nThis study will compare readings from the arm cuff (non-invasive) with those from a thin tube placed inside an artery (invasive), which is more accurate but also more uncomfortable and carries some risks.\n\nResearchers will use a method called error grid analysis to see how closely the cuff readings match the invasive ones. They want to find out if the cuff is accurate enough to be used safely in these surgeries. If it is, patients might not need an invasive line as often in the future.\n\nPeople 18 years or older who are already going to have invasive blood pressure monitoring during planned thoracic surgery with one-lung ventilation may be able to join the study. The research team will collect blood pressure measurements about every 20 minutes during surgery, as well as basic information like age, weight, and what medications are given.",[449],"Non-Invasive Blood Pressure Monitoring During Thoracoscopic Surgery With One-Lung Ventilation",[451,452,453,454,455,456],"Non-invasive blood pressure","Invasive arterial pressure","Thoracoscopic surgery","One-lung ventilation","Intraoperative monitoring","Error grid analysis","2025-07-30",{"date":459,"type":38},"2025-08-06",{"date":461,"type":23},"2025-09-01",{"date":463,"type":23},"2025-11-15",{"name":44,"class":45},{"id":466,"slug":467,"hasResults":12,"nctId":468,"briefTitle":469,"officialTitle":470,"acronym":4,"eligibilityCriteria":471,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":472,"targetDuration":4,"studyType":144,"phases":4,"briefSummary":474,"conditions":475,"keywords":477,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":457,"lastUpdatePostDateStruct":481,"startDateStruct":482,"completionDateStruct":483,"leadSponsor":484,"locationsCount":46},"100601202","how-accurate-is-non-invasive-blood-pressure-monitoring-during-trendelenburg-laparoscopic-surgery-100601202","NCT07107425","How Accurate Is Non-Invasive Blood Pressure Monitoring During Trendelenburg Laparoscopic Surgery?","Accuracy of Non-Invasive Blood Pressure Monitoring During Laparoscopic Surgery in the Trendelenburg Position: A Prospective Error Grid Analysis","Inclusion Criteria:\n\n* Age 18 years or older\n* Scheduled to undergo laparoscopic surgery in the Trendelenburg position\n* Will receive invasive arterial blood pressure monitoring as part of routine clinical care\n\nExclusion Criteria:\n\n* Has peripheral artery disease\n* Has congestive heart failure",{"count":473,"type":23},100,"This study will test how accurate a blood pressure cuff is during certain types of surgery.\n\nDuring some abdominal surgeries done with small tools and a camera (called laparoscopic surgery), doctors place patients in a head-down position called the Trendelenburg position. In this position, it may be harder for the blood pressure cuff on the arm to give correct readings. This study will compare the cuff's readings (non-invasive) with readings from a thin tube placed inside an artery (invasive), which is more accurate but also more risky and uncomfortable.\n\nThe researchers will use a method called error grid analysis to check how closely the cuff readings match the invasive ones. They hope to learn if the blood pressure cuff is accurate enough to be used safely in this kind of surgery. If it is, doctors may not need to use the invasive method as often.\n\nPeople 18 years or older who are already going to have invasive blood pressure monitoring as part of their planned surgery can join the study. The study will collect blood pressure measurements about every 20 minutes during surgery, as well as basic information like age, weight, and what medicines are given.",[476],"Non-Invasive Blood Pressure Monitoring in Trendelenburg Position",[478,479,451,452,456,480],"Trendelenburg position","Laparoscopic surgery","Hemodynamic monitoring",{"date":459,"type":38},{"date":461,"type":23},{"date":463,"type":23},{"name":44,"class":45},{"id":486,"slug":487,"hasResults":12,"nctId":488,"briefTitle":489,"officialTitle":490,"acronym":491,"eligibilityCriteria":492,"healthyVolunteers":12,"sex":228,"minAge":19,"maxAge":280,"enrollmentInfo":493,"targetDuration":4,"studyType":24,"phases":494,"briefSummary":495,"conditions":496,"keywords":4,"overallStatus":186,"whyStopped":4,"lastUpdateSubmitDate":498,"lastUpdatePostDateStruct":499,"startDateStruct":501,"completionDateStruct":503,"leadSponsor":504,"locationsCount":46},"100593138","pecs-ii-vs-esp-in-nociception-level-index-guided-breast-surgery-100593138","NCT07002541","PECS-II vs ESP in Nociception Level Index Guided Breast Surgery","NOL-Guided Intraoperative Remifentanil Consumption With PECS-II and Erector Spinae Plane Blocks in Breast Surgery: A Randomized Controlled Trial","NOL","Eligibility Criteria This study involves adult female patients undergoing elective breast surgery for benign or malignant conditions. The goal is to evaluate the effectiveness of regional anesthesia techniques (PECS-II and ESP blocks) in reducing intraoperative opioid consumption, guided by Nociception Level Index (NOL) monitoring.\n\nInclusion Criteria:\n\nFemale patients aged 18 to 80 years ASA Physical Status Classification I-III\n\nScheduled for elective unilateral or bilateral breast surgery, including one or more of the following:\n\nLumpectomy with axillary lymph node biopsy or dissection Breast reconstruction Breast reduction Mastopexy Implant expander removal or placement\n\nExclusion Criteria:\n\nMorbid obesity (BMI \\> 40 kg\u002Fm²) Presence of non-sinus cardiac rhythm Chronic opioid use (defined as daily use for \\>2 weeks in the last month or total use \\>4 weeks) History of opioid abuse or dependence Comorbidities causing moderate to severe functional limitation Inability to communicate with study personnel or follow instructions Pregnancy or breastfeeding Known allergy or hypersensitivity to bupivacaine or any study-related medication\n\n\\-",{"count":446,"type":23},[26],"Background:\n\nBreast surgery is often associated with significant perioperative pain. While systemic opioids are commonly used, their side effects (nausea, vomiting, respiratory depression, delayed recovery) have encouraged the adoption of regional anesthesia techniques for better analgesia and reduced opioid requirements. PECS-II and Erector Spinae Plane (ESP) blocks are two effective regional techniques frequently utilized in breast surgery. However, comparative data on their impact on intraoperative opioid consumption under nociception-guided anesthesia remains limited.\n\nThe Nociception Level Index (NOL) is an objective monitoring tool that integrates multiple physiological signals (e.g., heart rate variability, skin conductance, pulse amplitude) to assess nociceptive responses in real-time. When used intraoperatively, it enables more precise opioid titration, potentially optimizing analgesia while minimizing opioid exposure.\n\nObjective:\n\nTo compare the efficacy of PECS-II and ESP blocks in reducing intraoperative remifentanil consumption during breast surgery under general anesthesia guided by NOL monitoring.\n\nMethods:\n\nThis prospective, randomized controlled trial was conducted at Koç University Hospital following ethical approval. Ninety female patients aged 18-80 years, classified as ASA I-III and scheduled for elective mastectomy or other breast surgeries, were randomly assigned into three groups (n=30 each):\n\nGroup 1 (PECS-II Block) Group 2 (ESP Block) Group 3 (Control - no block) Regional blocks were performed before surgery with ultrasound guidance. PECS-II block was administered at the 3rd to 5th rib levels in the mid-axillary line using 30 mL of 0.3% bupivacaine. ESP block was applied at T2-T5 levels with a total of 20 mL 0.5% bupivacaine.\n\nAll patients received standardized general anesthesia, including propofol, fentanyl, rocuronium, and desflurane maintenance. Remifentanil infusion (0.05-0.1 μg\u002Fkg\u002Fmin) was titrated based on NOL values every 5 minutes: increased by 0.03 μg\u002Fkg\u002Fmin if NOL \\>25, and decreased by 0.03 μg\u002Fkg\u002Fmin if NOL \\\u003C10.\n\nData collected included:\n\nTotal intraoperative remifentanil consumption (primary outcome) NOL scores every 5 minutes Postoperative pain scores (NRS) at 1st, 6th, 12th, and 24th hours (at rest and with arm abduction) Total opioid consumption (morphine, tramadol) in the first 24 hours Opioid-related side effects (nausea, vomiting, pruritus) Length of hospital stay Blinding was applied to data collectors (pain nurses and anesthesia technicians), but due to the nature of the procedures, surgeons and anesthesiologists were not blinded.\n\nStatistical Analysis:\n\nData were analyzed using SPSS v26. Continuous variables were tested for normality (Shapiro-Wilk), and analyzed with t-tests or Mann-Whitney U as appropriate. Categorical variables were compared using Chi-square tests. Significance was set at p\\\u003C0.05.\n\nExpected Outcomes and Contribution:\n\nIt is hypothesized that both PECS-II and ESP blocks will significantly reduce intraoperative remifentanil consumption compared to the control group. Furthermore, these blocks may improve postoperative pain control, reduce opioid-related side effects, and shorten recovery time.\n\nThis study aims to clarify the relative efficacy of two widely used regional blocks in the context of objective, nociception-guided anesthesia. The findings are expected to support evidence-based use of regional techniques in breast surgery and contribute to the growing body of literature emphasizing opioid-sparing strategies in perioperative care.",[497,30],"Intraoperative Pain","2025-05-24",{"date":500,"type":38},"2025-06-03",{"date":502,"type":38},"2024-12-01",{"date":404,"type":23},{"name":44,"class":45},{"id":506,"slug":507,"hasResults":12,"nctId":508,"briefTitle":509,"officialTitle":510,"acronym":511,"eligibilityCriteria":512,"healthyVolunteers":12,"sex":18,"minAge":4,"maxAge":4,"enrollmentInfo":513,"targetDuration":4,"studyType":24,"phases":515,"briefSummary":516,"conditions":517,"keywords":519,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":524,"lastUpdatePostDateStruct":525,"startDateStruct":527,"completionDateStruct":529,"leadSponsor":531,"locationsCount":46},"100559843","education-program-on-evidence-based-practices-on-nurses-competencies-and-clinical-decision-making-levels-100559843","NCT06569407","Education Program on Evidence-based Practices on Nurses' Competencies and Clinical Decision-Making Levels","The Effect of Online Training Program on Evidence-Based Practices on Nurses' Competencies for Evidence-Based Practices and Clinical Decision-Making Levels: A Randomized Controlled Trial","RCT","Inclusion Criteria:\n\n* Nurses who agree to participate in the study and work in inpatient wards will be included.\n\nExclusion Criteria:\n\n* Nurses who do not agree to participate in the study and do not work in inpatient wards will not be included in the sample.",{"count":514,"type":23},70,[26],"This clinical trial aims to develop an online education program and an educational booklet for nurses on EBP and to compare the evidence-based competencies and clinical decision-making levels of nurses trained with these two methods.\n\nHypotheses of the Study Ho: There is no statistically significant difference between the nurses' competency levels who participated in the online education developed for evidence-based practices and those who were informed of the educational booklet.\n\nH1. The nurses' competency levels who participated in the online education developed for evidence-based practices are statistically higher than those who were informed of the educational booklet.\n\nHo: There is no statistically significant difference between the clinical decision-making levels of nurses who participated in the online education developed for evidence-based practices and nurses who were informed with the educational booklet.\n\nH1: The clinical decision-making levels of the nurses who participated in the online education developed for evidence-based practices are statistically higher than those informed with the educational booklet.\n\nParticipants will:\n\nThe nurses in the intervention group are expected to fill in the data collection tools (Introductory Information Form for Nurses, Evidence-Based Practice Competency Scale, Clinical Decision Making Scale in Nursing) before the education and then participate in the education about evidence-based practices on the online platform and fill in the data collection tools (Evidence-Based Practice Competency Scale, Clinical Decision Making Scale in Nursing and Education Evaluation Form) 20 days after the education.\n\nThe nurses in the control group were expected to complete the data collection tools (Introductory Information Form for Nurses, Evidence-Based Practice Competency Scale, Clinical Decision Making Scale in Nursing) before the education booklet was given and 20 days after the education.",[518],"Evidence Based Practice",[518,520,521,522,374,211,523],"Clinical Desicion Making","Educational Program","Online Training","Educational Intervention","2025-03-05",{"date":526,"type":38},"2025-03-10",{"date":528,"type":23},"2025-08",{"date":530,"type":23},"2027-11",{"name":44,"class":45},{"id":533,"slug":534,"hasResults":12,"nctId":535,"briefTitle":536,"officialTitle":537,"acronym":4,"eligibilityCriteria":538,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":539,"targetDuration":4,"studyType":144,"phases":4,"briefSummary":541,"conditions":542,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":545,"lastUpdatePostDateStruct":546,"startDateStruct":548,"completionDateStruct":550,"leadSponsor":552,"locationsCount":4},"100580498","trend-correlation-between-end-tidal-and-arterial-carbon-dioxide-during-laparoscopic-surgery-in-trendelenburg-position-100580498","NCT06838078","Trend Correlation Between End-Tidal and Arterial Carbon Dioxide During Laparoscopic Surgery in Trendelenburg Position","Evaluation of the Trend Correlation Between End-Tidal and Arterial Carbon Dioxide Partial Pressures During Laparoscopic Surgery in the Trendelenburg Position: A Prospective Observational Study","Inclusion Criteria:\n\n* Scheduled to undergo laparoscopic surgery in the Trendelenburg position\n* Planned to receive invasive arterial blood pressure monitoring as part of routine clinical care (independent of the study)\n\nExclusion Criteria:\n\n* Chronic obstructive pulmonary disease\n* Pulmonary hypertension\n* Active systemic infection",{"count":540,"type":23},79,"In this study, we want to find out whether a person's \"end-tidal carbon dioxide\" (ETCO₂)-a value measured from the air they breathe out-accurately reflects the amount of carbon dioxide in their blood, called \"arterial carbon dioxide\" (PaCO₂).\n\nWe are focusing on people having laparoscopic (keyhole) surgery in the Trendelenburg position, which involves tilting the patient's head down to help the surgeon see the surgical area better. This position can sometimes affect carbon dioxide levels in the blood. Right now, doctors must draw blood samples to measure the PaCO₂ level. If we can show that ETCO₂ readings are reliable, doctors may not need to draw blood samples as often.\n\nDuring surgery, patients already need a small tube (catheter) in an artery so doctors can closely monitor their blood pressure. Whenever the anesthesiologist decides a blood sample is needed, we will note the blood's PaCO₂ level and compare it with the ETCO₂ reading taken at the same time. We will also record other measurements like heart rate, blood pressure, and temperature.\n\nBy comparing these measurements, we hope to learn if the ETCO₂ readings can reliably match the changes in PaCO₂ over time, making it a useful tool to monitor carbon dioxide levels in this type of surgery without needing as many blood tests. We plan to include 79 patients in this study, which should give us enough measurements to see how closely these two methods match.",[543,544],"Laparoscopic Surgery","Trendelenburg Position","2025-02-15",{"date":547,"type":38},"2025-02-20",{"date":549,"type":23},"2025-04-01",{"date":551,"type":23},"2025-06-15",{"name":44,"class":45},{"id":554,"slug":555,"hasResults":12,"nctId":556,"briefTitle":557,"officialTitle":558,"acronym":4,"eligibilityCriteria":559,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":560,"targetDuration":4,"studyType":144,"phases":4,"briefSummary":562,"conditions":563,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":568,"lastUpdatePostDateStruct":569,"startDateStruct":571,"completionDateStruct":572,"leadSponsor":574,"locationsCount":4},"100580330","trending-ability-of-end-tidal-capnography-to-reflect-arterial-carbon-dioxide-changes-in-one-lung-ventilation-100580330","NCT06835894","Trending Ability of End-Tidal Capnography to Reflect Arterial Carbon Dioxide Changes in One-Lung Ventilation","Do End-Tidal Capnography Trends Reflect Changes in Arterial Carbon Dioxide Partial Pressure During One-Lung Ventilation for Thoracoscopic Surgery? A Prospective Observational Study","Inclusion Criteria:\n\n* Patients undergoing thoracoscopic lung surgery with one-lung ventilation\n* Patients requiring invasive arterial blood pressure monitoring\n\nExclusion Criteria:\n\n* Chronic obstructive pulmonary disease (COPD)\n* Pulmonary hypertension\n* Systemic infection",{"count":561,"type":23},115,"In this study, we want to find out if measuring carbon dioxide from a patient's breath (end-tidal CO₂ or ETCO₂) can reliably reflect changes in blood carbon dioxide levels (arterial CO₂ or PaCO₂) during lung surgery. Instead of just looking at individual values, we are specifically investigating whether ETCO₂ and PaCO₂ rise and fall in the same direction over time.\n\nDuring lung surgery, patients often need \"one-lung ventilation,\" where only one lung is used for breathing while the other is deflated to help the surgeon. This can cause carbon dioxide levels in the blood to change, which are typically monitored by taking blood samples. If ETCO₂ trends closely follow PaCO₂ trends, doctors may not need to take as many blood samples.\n\nPatients in this study will already have a small tube in an artery for monitoring blood pressure. Whenever a blood test is taken, we will compare the blood CO₂ level with the ETCO₂ reading at that moment. We will also track heart rate, blood pressure, and body temperature.\n\nBy comparing these measurements, we hope to learn whether ETCO₂ reliably follows the same trends as PaCO₂, making it a useful tool for monitoring carbon dioxide levels in lung surgery with fewer blood tests.",[564,565,566,567],"Video-Assisted Thoracoscopic Surgery","One-Lung Ventilation","Capnography","Blood Gas Analysis","2025-02-14",{"date":570,"type":38},"2025-02-19",{"date":549,"type":23},{"date":573,"type":23},"2025-07-10",{"name":44,"class":45},{"id":576,"slug":577,"hasResults":12,"nctId":578,"briefTitle":579,"officialTitle":580,"acronym":4,"eligibilityCriteria":581,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":20,"enrollmentInfo":582,"targetDuration":4,"studyType":24,"phases":583,"briefSummary":584,"conditions":585,"keywords":588,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":591,"lastUpdatePostDateStruct":592,"startDateStruct":594,"completionDateStruct":596,"leadSponsor":597,"locationsCount":4},"100575315","development-of-a-nursing-care-bundle-to-prevent-pressure-injuries-and-its-impact-on-rates-and-costs-100575315","NCT06770686","Development of a Nursing Care Bundle to Prevent Pressure Injuries and Its Impact on Rates and Costs","Development of Nursing Care Bundle for the Prevention of Pressure Injuries, the Impact on the Rate and Cost of Pressure Injuries","Inclusion Criteria:\n\n* Being 18 years of age or older\n* Patients who fall into all risk categories assessed by the Braden scale\n* Not having developed a pressure injury anywhere on their body\n* Expectation of a minimum of 24 hours or more in the intensive care unit\n\nExclusion Criteria:\n\n* Being 18 years of age or younger\n* Having and developing a pressure injury anywhere on their body\n* Expectation of a less than 24-hour stay in the intensive care unit",{"count":446,"type":23},[26],"Pressure injuries (PIs) represent a significant clinical complication for patients worldwide and pose financial and quality challenges for healthcare systems. These wounds, which are highly challenging to treat and care for both patients and caregivers, lead to physical and psychological trauma, negatively affect daily life activities, reduce quality of life, and increase care costs (Padula et al., 2019; Yilmazer \\& Tüzer, 2022). Moreover, the expenses associated with treatment are 2.5 times higher than those for prevention (Lyder \\& Ayello, 2007). Additionally, they often prolong hospital stays and increase the time nurses spend on care (Yilmazer \\& Tüzer, 2022).\n\nAccording to the National Pressure Injury Advisory Panel (NPIAP, 2019), providing high-quality care for patients with PIs requires adopting a multidisciplinary, standardized care approach tailored to the specific needs of patients (Heasler, 2019). Past and current literature supports the use of evidence-based care bundles to reduce PIs (Coyer et al., 2015; Chaboyer et al., 2015; Amr et al., 2017; Deakin et al., 2020; Yilmazer \\& Tüzer, 2022; Wang et al., 2023). A care bundle is a critical element for standardizing and enhancing the quality of nursing care through the utilization of evidence-based clinical practice guidelines by healthcare professionals. Therefore, adopting these evidence-based approaches will improve the consistency and quality of nursing care, enhance patient outcomes, and reduce institutional costs. Moreover, the use of care bundles during interventions promotes teamwork and collaboration while supporting the development of a common language (Anderson et al., 2015; Institute for Healthcare Improvement, 2021).\n\nThis study aims to reduce PIs, enhance the quality of patient care, lower healthcare costs, and improve overall patient outcomes through the development and implementation of a nursing care bundle based on evidence in the literature. The widespread use of the care bundle, grounded in achieved outcomes, will contribute to the prevention of PIs. Additionally, it will serve as a supportive tool for nurses to improve the quality of care.",[586,587],"Pressure Injury","Hospital Acquired Pressure Ulcer",[589,590],"Care Bundles","Cost","2025-01-07",{"date":593,"type":38},"2025-01-13",{"date":595,"type":23},"2025-01-01",{"date":549,"type":23},{"name":44,"class":45},{"id":599,"slug":600,"hasResults":12,"nctId":601,"briefTitle":602,"officialTitle":603,"acronym":4,"eligibilityCriteria":604,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":280,"enrollmentInfo":605,"targetDuration":4,"studyType":24,"phases":607,"briefSummary":608,"conditions":609,"keywords":614,"overallStatus":186,"whyStopped":4,"lastUpdateSubmitDate":618,"lastUpdatePostDateStruct":619,"startDateStruct":621,"completionDateStruct":622,"leadSponsor":624,"locationsCount":46},"100548877","tpvb-or-spsipb-in-pain-management-after-vats-100548877","NCT06426706","TPVB or SPSIPB in Pain Management After VATS","Paravertebral Block or Serratus Posterior Superior Intercostal Plane Block in Pain Management After Video-Assisted Thoracoscopic Surgery: A Randomized Controlled Clinical Trial","Inclusion Criteria:\n\n* Patients between the age of 18-80 undergoing video-assisted thoracoscopic surgery\n\nExclusion Criteria:\n\n* Allergy to local anaesthetics Chronic opioid use history Patients with psychiatric disorders Patients who are not open to communication Patients with chronic organ failure Patients that do not give consent Patients that need emergency surgery within the first 24 hours of the initial surgery",{"count":606,"type":23},44,[26],"The goal of this clinical trial is to compare the analgesic efficacy of thoracal paravertebral block (TPVB) and serratus posterior superior intercostal plane block (SPSIPB) in patients undergoing video-assisted thoracoscopic surgery (VATS). The main questions it aims to answer are:\n\nHow will the total perioperative opioid consumption of the patients receiving two different blocks change? How will TPVB and SPSIPB effect the patients' numeric rating scores for pain in the postoperative 24-hour period? How will TPVB and SPSIPB effect the incidence of opioid related side effects?\n\nParticipants will be divided in two groups:\n\nTPVB group will receive a TPVB before the surgery. SPSIPB group will receive a SPSIPB nerve block before the surgery. Researchers will compare the results between the groups to see the postoperative effects concerning opioid consumption as well as the pain scores, respiratory parameters and opioid associated side effects.\n\nThe hypothesis of this study is that participants receiving SPSIPB for VATS will have a less total opioid consumption 24 hours postoperatively.",[610,611,612,613],"Video-assisted Thoracoscopic Surgery","Paravertebral Block","Serratus Posterior Superior Intercostal Plane Block","Regional Anesthesia Morbidity",[615,616,617],"video-assisted thoracoscopic surgery","paravertebral block","serratus posterior superior intercostal plane block","2025-01-02",{"date":620,"type":38},"2025-01-03",{"date":620,"type":23},{"date":623,"type":23},"2025-03-15",{"name":44,"class":45},{"id":626,"slug":627,"hasResults":12,"nctId":628,"briefTitle":629,"officialTitle":630,"acronym":4,"eligibilityCriteria":631,"healthyVolunteers":12,"sex":18,"minAge":632,"maxAge":633,"enrollmentInfo":634,"targetDuration":4,"studyType":24,"phases":636,"briefSummary":637,"conditions":638,"keywords":640,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":643,"lastUpdatePostDateStruct":644,"startDateStruct":646,"completionDateStruct":648,"leadSponsor":650,"locationsCount":46},"100559744","effect-of-using-a-dragon-design-nebulizer-mask-on-treatment-duration-compliance-and-fear-in-children-100559744","NCT06568120","Effect of Using a Dragon Design Nebulizer Mask on Treatment Duration, Compliance and Fear in Children","Effect of Using a Dragon Design Nebulizer Mask on Treatment Duration, Compliance and Fear in Children Presenting to the Emergency Department: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Aged between 3-6 years,\n* Presenting to the emergency department with a respiratory problem (such as an upper respiratory tract infection) requiring nebulizer treatment,\n* In general good health and suitable for nebulizer treatment (i.e., not having conditions like severe allergies or chronic respiratory failure),\n* Possessing age-appropriate language and communication skills,\n* Not previously familiar with the dragon-themed masks,\n* Having parental consent.\n\nExclusion Criteria:\n\n* Children with major medical or psychiatric comorbidities as reported by the physician, nurse, or parent,\n* Children with a chronic health condition requiring regular nebulizer use (such as asthma),\n* Children with a fever of 38°C (100.4°F) or higher,\n* Children who have started treatment with sedative or anticonvulsant medications,\n* Children and parents with visual, auditory, verbal, or cognitive impairments that would interfere with the use of the intervention equipment.","3 Years","6 Years",{"count":635,"type":23},140,[26],"Incorporating playful elements into medical devices has been shown to enhance the overall experience for pediatric patients. Children want a healthcare setting that is spacious, creative, imaginative, and contemporary. Additionally, a current retrospective study of 127,368 pediatric patients indicates that 71.26% of the visits involved children under five years old, and 23.64% of the cases were due to respiratory infections. This information highlights the prevalence of inhaler therapy in emergency departments, particularly among young children with respiratory issues. This study aims to evaluate the impact of using dragon\u002Fturtle-themed nebulizer masks on treatment application time, treatment adherence, and fear levels in children who present to emergency rooms. By addressing these environmental and procedural challenges, the study seeks to improve the overall experience and outcomes for pediatric patients undergoing inhaler therapy.",[639],"Fear",[97,641,642],"emergency room","fear","2024-08-20",{"date":645,"type":38},"2024-08-23",{"date":647,"type":23},"2024-10",{"date":649,"type":23},"2025-10",{"name":44,"class":45},{"id":652,"slug":653,"hasResults":12,"nctId":654,"briefTitle":655,"officialTitle":656,"acronym":4,"eligibilityCriteria":657,"healthyVolunteers":173,"sex":18,"minAge":4,"maxAge":4,"enrollmentInfo":658,"targetDuration":4,"studyType":24,"phases":660,"briefSummary":661,"conditions":662,"keywords":664,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":669,"lastUpdatePostDateStruct":670,"startDateStruct":671,"completionDateStruct":673,"leadSponsor":675,"locationsCount":46},"100559314","digital-training-module-for-sustainable-education-of-pediatric-oncology-nurses-100559314","NCT06562517","Digital Training Module for Sustainable Education of Pediatric Oncology Nurses","Development of a Digital Training Module for Sustainable Education of Pediatric Oncology Nurses and Evaluation of Its Effectiveness","Inclusion Criteria:\n\n* Volunteer to participate in the research,\n* Working in a pediatric oncology clinic,\n* Having at least one year of experience in pediatric oncology.\n\nExclusion Criteria:\n\n* Lack of Internet literacy,\n* Incomplete filling of data collection forms.",{"count":659,"type":23},104,[26],"Pediatric oncology nurses are healthcare professionals who constantly communicate with children and their families for 24 hours, and take professional roles and responsibilities in areas such as care planning, a continuation of treatment, and symptom management.However, there is no standard undergraduate education program accepted worldwide in the field of pediatric oncology nursing. For example, undergraduate nursing education in Türkiye is carried out in line with the Nursing National Core Education Program (NNCEP), and information about pediatric oncology nursing is included in the curriculum of specific courses in undergraduate programs. In addition, nurses graduate without specializing in any field in our country. Therefore, the education of pediatric oncology nurses and the continuity of education is an essential problem in developing and low-middle-income countries like our country. This prospective study in randomized controlled pre-test-post-test design aimed to develop an online website consisting of information and support modules for the care of children with cancer for sustainable pediatric oncology nursing education in Türkiye.",[663],"Pediatric Cancer",[665,666,667,668],"education","nursing","development","pediatric oncology","2024-08-16",{"date":643,"type":38},{"date":672,"type":23},"2024-09-01",{"date":674,"type":23},"2025-03-01",{"name":44,"class":45},""]