[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Kocaeli City Hospital\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":415},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,15,0,[8,40,73,98,130,162,181,209,240,267,295,319,344,372,392],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":28,"lastUpdatePostDateStruct":29,"startDateStruct":32,"completionDateStruct":34,"leadSponsor":36,"locationsCount":39},"100643620","qor-15t-in-cardiac-surgery-100643620",false,"NCT07593794","QoR-15T in Cardiac Surgery","Validity and Reliability of the Turkish Quality of Recovery-15 (QoR-15T) Scale in Cardiac Surgery Patients: A Prospective Observational Cohort Study","QoR15T-CARDİAC","Inclusion Criteria:\n\n* Adult patients aged 18 years and older.\n* Patients scheduled for elective cardiac surgery (CABG, valve replacement, or aortic surgery).\n* Patients capable of understanding and answering the Turkish version of the QoR-15 questionnaire.\n* Patients who provide written informed consent.\n\nExclusion Criteria:\n\n* Emergency surgeries or revision surgeries\n* Patients with severe cognitive impairment or psychiatric disorders that prevent completion of the scale\n* Patients who refuse to participate at any stage.","ALL","18 Years",{"count":20,"type":21},150,"ESTIMATED","OBSERVATIONAL","The objective of this prospective observational cohort study is to evaluate the validity, reliability, and responsiveness of the Turkish version of the Quality of Recovery-15 (QoR-15T) scale in adult patients undergoing elective cardiac surgery. While the QoR-15T has been validated for general surgery in Turkey, its performance remains to be established in high-risk cardiac surgery populations involving cardiopulmonary bypass and intensive care stays.Approximately 150 patients at Kocaeli City Hospital will be enrolled. The study will compare the patients' QoR-15T scores-recorded preoperatively and on the 7th postoperative day-with the Global Recovery Visual Analog Scale (VAS) to determine construct validity.",[25,26],"Postoperative Recovery","Patient Reported Outcome Measures","RECRUITING","2026-06-04",{"date":30,"type":31},"2026-06-08","ACTUAL",{"date":33,"type":31},"2026-05-18",{"date":35,"type":21},"2026-10-15",{"name":37,"class":38},"Kocaeli City Hospital","OTHER_GOV",1,{"id":41,"slug":42,"hasResults":11,"nctId":43,"briefTitle":44,"officialTitle":45,"acronym":46,"eligibilityCriteria":47,"healthyVolunteers":48,"sex":17,"minAge":49,"maxAge":18,"enrollmentInfo":50,"targetDuration":52,"studyType":22,"phases":4,"briefSummary":53,"conditions":54,"keywords":60,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":28,"lastUpdatePostDateStruct":66,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":39},"100639547","quality-of-life-and-pain-after-appendectomy-in-children-100639547","NCT07629362","Quality of Life and Pain After Appendectomy in Children","Chronic Postoperative Pain After Appendectomy: A Prospective Observational Study","CAPA-Peds","Inclusion Criteria:\n\nChildren between the ages of 8-18 years who underwent appendectomy, who had ASA physical status I-II\n\nExclusion Criteria:\n\nChildren who aged under 8 and over 18 years, who had American Society of Anesthesiologists (ASA) physical status III or higher, who had a history of previous surgery in the right lower abdominal quadrant, who had psychiatric disorders, who had preoperative chronic abdominal pain",true,"8 Years",{"count":51,"type":21},231,"3 Months","Acute appendicitis is one of the most common emergency general surgical conditions worldwide and represents the leading cause of emergency abdominal surgery in children. In some cases, appendectomy may result in persistent or recurrent pain in the right iliac fossa, which may negatively affect quality of life, particularly in children. The primary aim of this study is to determine the prevalence of chronic pain at the third postoperative month in pediatric patients who underwent appendectomy. The age, sex, body mass index, and comorbidities of patients aged 8-18 years who underwent appendectomy will be recorded. Pain in children who met the inclusion criteria was assessed using the Numeric Rating Scale (NRS). To evaluate the effects of pain on quality of life, the child and parent versions of the Pediatric Quality of Life Inventory (PedsQL) were administered at the third postoperative month. In addition, the Functional Disability Inventory (FDI) was used at the third postoperative month to assess the impact of pain on the patient's functional status.",[55,56,57,58,59],"Chronic Pain, Postoperative","Quality of Life","Functional Ability","Appendectomy","Numerical Rating Scale",[61,62,63,64],"chronic pain","appendectomy","FDI","PedsQL","NOT_YET_RECRUITING",{"date":67,"type":31},"2026-06-05",{"date":69,"type":21},"2026-07-01",{"date":71,"type":21},"2027-02-25",{"name":37,"class":38},{"id":74,"slug":75,"hasResults":11,"nctId":76,"briefTitle":77,"officialTitle":78,"acronym":4,"eligibilityCriteria":79,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":80,"enrollmentInfo":81,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":83,"conditions":84,"keywords":89,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":92,"startDateStruct":94,"completionDateStruct":95,"leadSponsor":97,"locationsCount":39},"100637381","analgesic-efficiency-of-sipspb-vs-icnb-in-vats-surgery-100637381","NCT07577908","Analgesic Efficiency of SIPSPB vs ICNB in VATS Surgery","Comparison Of The Analgesic Effectiveness Of Ultrasonography-Guided Serratus Posterıor Superior Intercostal Plane (SPSIP) Block And Intercostal Nerve (ICN) Block In Video-Assisted Thoracoscopic Surgery Patients","Inclusion Criteria:\n\n* Aged 18-80 years,\n* American Society of Anesthesiologists (ASA) physical status I-III\n* Patients who have provided informed consent to participate in the study\n\nExclusion Criteria:\n\n* Patients who refuse to participate in the study by not signing the informed consent\n* Patients classified as ASA \\> 3, according to the system established by the American Society of Anesthesiologists\n* Patients unable to understand the use of the NPR Scale or the PCA device that will be used for postoperative analgesia\n* Coagulation disorders or anticoagulant therapy contraindicating regional anesthesia\n* Patients with allergies to analgesic and\u002For anesthetic drugs\n* Infection at the block injection site\n* Patients whose surgical procedure is intraoperatively converted to an open pulmonary resection","80 Years",{"count":82,"type":21},80,"This study aims to evaluate the effectiveness of Serratus Posterior Superior Intercostal Plane (SPSIP) block compared to Intercostal Nerve (ICN) block in terms of postoperative pain control, reduction of opioid analgesic consumption, minimization of postoperative respiratory complications, and increase patient satisfaction (using a 5-point Likert scale) in patients undergoing video-assisted thoracoscopic surgery (VATS).",[85,86,87,88],"Intercostal Nerve Block","Serratus Posterior Superior Intercostal Plane Block","Post-operative Pain Management","VATS",[90,91,88],"Serratus posterior superior intercostal plane block","intercostal nerve block",{"date":93,"type":31},"2026-05-20",{"date":33,"type":31},{"date":96,"type":21},"2026-08-01",{"name":37,"class":38},{"id":99,"slug":100,"hasResults":11,"nctId":101,"briefTitle":102,"officialTitle":103,"acronym":104,"eligibilityCriteria":105,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":106,"targetDuration":4,"studyType":108,"phases":109,"briefSummary":111,"conditions":112,"keywords":118,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":123,"lastUpdatePostDateStruct":124,"startDateStruct":126,"completionDateStruct":127,"leadSponsor":129,"locationsCount":39},"100630220","comparison-of-awake-tracheal-intubation-methods-100630220","NCT07484841","Comparison of Awake Tracheal Intubation Methods","A Comparison of Three Difficult Intubation Techniques in Patients With Anticipated Difficult Intubation: A Prospective, Randomized, Parallel-group Clinical Trial","ATI","Inclusion Criteria:\n\n* Adult patients aged 18 and older\n* Patients classified as ASA I-II according to the American Society of Anesthesiologists (ASA) classification\n* Patients scheduled for elective surgery\n* Patients expected to require difficult mask ventilation, difficult laryngoscopy, or difficult tracheal intubation; patients expected to have short apnea periods (Planjuan goiter); patients at risk of aspiration; patients expected to require difficult rescue techniques; and patients with a reported history of difficult intubation\n* Patients scheduled for intubation using the awake tracheal intubation (ATI) method\n* Individuals who have agreed to participate in the study by signing an informed consent form\n\nExclusion Criteria:\n\n* Patients with a mouth opening \\\u003C1.5 cm\n* Patients requiring emergency intubation or emergency surgery (situations where there is insufficient time to administer ATI)\n* Patients who cannot cooperate (mental incapacity, impaired consciousness, inability to communicate, etc.)\n* Patients with known allergies to lidocaine or other local\u002Ftopical anesthetic agents used\n* Pregnancy\n* Patients with a history of severe cardiac arrhythmia or hemodynamic instability (due to increased risk during intubation)\n* Patients who have previously undergone tracheostomy or whose airway is technically obstructed due to anatomical deformity\n* Patients who refuse to participate in the study or who do not provide informed consent",{"count":107,"type":21},201,"INTERVENTIONAL",[110],"NA","The aim of this study was to compare three different awake tracheal intubation technique\n\n-fiberoptic bronchoscopy (ATI:FB), videolaryngoscopy (ATI:VL), and fiberoptic bronchoscopy via a supraglottic airway device (ATI:SAD)- in terms of success rates, intubation times, and complications. Additionally, the study aims to evaluate the reliability of the SAD-assisted ATI method and its potential to contribute to the literature.",[113,114,115,116,117],"Airway Management Assessment","Awake Endotracheal Intubation","Awake Fiberoptic Nasal Intubation","Videolaryngoscopy","Supraglottic Airway Device Insertion",[119,120,121,122],"videolaryngoscopy","awake tracheal intubation","fiberoptic bronchoscopy","aintree catheter","2026-03-18",{"date":125,"type":31},"2026-03-20",{"date":125,"type":21},{"date":128,"type":21},"2028-06-20",{"name":37,"class":38},{"id":131,"slug":132,"hasResults":11,"nctId":133,"briefTitle":134,"officialTitle":135,"acronym":136,"eligibilityCriteria":137,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":138,"targetDuration":4,"studyType":108,"phases":140,"briefSummary":141,"conditions":142,"keywords":146,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":154,"lastUpdatePostDateStruct":155,"startDateStruct":157,"completionDateStruct":159,"leadSponsor":161,"locationsCount":39},"100626954","care-bundle-for-prevention-of-skin-complications-and-edema-in-restrained-patients-100626954","NCT07442344","Care Bundle for Prevention of Skin Complications and Edema in Restrained Patients","Development and Evaluation of the Effectiveness of a Dermatological Complications and Edema Prevention Care Package in the Physical Constraint Zone","SCER-ICU","Inclusion Criteria:\n\n* • 18 years of age or older,\n\n  * For whom a physician has decided to apply physical restraint to the upper extremities and is about to begin doing so,\n  * With intact skin integrity in the area of physical restraint (no lacerations, wounds, ulcerations),\n  * Without oedema in the area of physical restraint,\n  * APACHE-2 score of 17 or higher (In the study by Tian et al. (2022), an APACHE-II score of 17 or higher was found to be associated with a low life expectancy),\n  * Individuals for whom written consent has been obtained from the patient's relatives regarding participation in the study.\n\nExclusion Criteria:\n\n* In the physical restraint area;\n\n  * Those with fractures or dislocations,\n  * Those with peripheral vascular disease or chronic venous insufficiency,\n  * Those with advanced skin disease (psoriasis, etc.),\n  * Those whose physical restraint was discontinued within the first 24 hours after it began for any reason (discharge, transfer to another clinic, death, lifting of the physical restraint decision by the physician, etc.).",{"count":139,"type":21},76,[110],"Physical restraint (restraint) is defined as the restriction of a patient's free body movements and the prevention of the patient's ability to move easily by healthcare professionals using physical or mechanical devices to prevent the patient from harming themselves or others. Physical restraints can be used by healthcare professionals for many purposes, particularly in intensive care units, such as ensuring patient safety, controlling aggressive and disruptive behavior, continuing patient care and treatment, and preventing the removal of medical equipment attached to the patient. However, when looking at the duration of physical restraint applications, it has been determined that they vary between 3-4 days. The longer the duration of physical restraint, the greater the likelihood of complications developing. In particular, long-term physical restraint can result in neurovascular and dermatological complications such as pressure injuries, edema, ecchymosis, redness, numbness, limited movement, increased temperature, discoloration, and nerve damage. The care package application is a model that improves patient care quality by simultaneously and comprehensively implementing 3-5 applications based on strong scientific evidence, prepared for the relevant area in the specified patient group. Care package applications are created to enable evidence-based practices outlined in guidelines to be used more effectively and practically in clinical settings. Within this context, the aim of this study is to develop a care package to prevent dermatological complications and edema that may occur in the restraint area in patients undergoing physical restraint in intensive care and to evaluate the effectiveness of this care package.",[143,144,145],"Edema","Dermatologic Complication","Physical Restraints",[147,148,149,150,151,152,153],"physical restraint","edema","laseration","ulceration","intensive care unit","nursing","ecchymosis","2026-02-27",{"date":156,"type":31},"2026-03-02",{"date":158,"type":21},"2026-03",{"date":160,"type":21},"2027-04",{"name":37,"class":38},{"id":163,"slug":164,"hasResults":11,"nctId":165,"briefTitle":166,"officialTitle":167,"acronym":4,"eligibilityCriteria":168,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":80,"enrollmentInfo":169,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":171,"conditions":172,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":174,"lastUpdatePostDateStruct":175,"startDateStruct":177,"completionDateStruct":178,"leadSponsor":180,"locationsCount":39},"100625280","antegrade-autologous-blood-reinfusion-after-cpb-100625280","NCT07420582","Antegrade Autologous Blood Reinfusion After CPB","The Effect of Antegrade Pump Blood Reinfusion Via Crystalloid \"Chase\" Technique on Postoperative Transfusion Requirements in Adult Cardiac Surgery Patients: A Prospective Observational Study","Inclusion Criteria:\n\n* Age 18 to 80 years\n* Patients undergoing elective, isolated coronary artery bypass grafting surgery using cardiopulmonary bypass (on-pump).\n\nExclusion Criteria:\n\n* Emergency or Redo cardiac surgery\n* Concomitant cardiac procedures (e.g., valve repair\u002Freplacement or aortic surgery).\n* Planned or intraoperative conversion to off-pump coronary artery bypass grafting\n* Preoperative hematocrit \\\u003C30% or known inherited\u002Facquired bleeding disorders.\n* Preoperative left ventricular ejection fraction \\\u003C30%.\n* Thrombocytopenia (e.g., platelet count \\\u003C100×10³\u002FµL) or abnormal coagulation tests.\n* Use of antiplatelet agents other than aspirin without appropriate discontinuation according to current guideline-recommended preoperative intervals.\n* Use of anticoagulant therapy without appropriate preoperative discontinuation according to current guideline recommendations.\n* Use of non-steroidal anti-inflammatory drugs (NSAIDs) without appropriate discontinuation prior to surgery.\n* Severe renal dysfunction (eGFR \\\u003C30 mL\u002Fmin\u002F1.73 m² or dialysis) and\u002For severe hepatic dysfunction (Child-Pugh B-C or coagulopathy).\n* Active infection or systemic inflammatory\u002Fautoimmune disease.\n* Active malignancy requiring ongoing treatment\n* Refusal or inability to provide written informed consent.",{"count":170,"type":21},130,"This prospective observational study aims to evaluate the effect of antegrade pump blood reinfusion using the crystalloid \"chase\" technique on postoperative transfusion requirements in adult patients undergoing cardiac surgery with cardiopulmonary bypass. At the end of cardiopulmonary bypass, blood remaining within the cardiopulmonary bypass circuit is reinfused antegradely through the arterial line using a crystalloid chase, without collection or storage. Blood remaining within the bypass circuit after surgery represents a valuable source of autologous blood, and its reinfusion may contribute to perioperative blood conservation strategies. Patients receiving antegrade pump blood reinfusion via the chase technique will be compared with those managed without reinfusion, without any intervention by the investigators. The primary outcome is postoperative blood transfusion requirement.",[173],"Coronary Artery Disease","2026-02-23",{"date":176,"type":31},"2026-02-24",{"date":174,"type":31},{"date":179,"type":21},"2026-06-15",{"name":37,"class":38},{"id":182,"slug":183,"hasResults":11,"nctId":184,"briefTitle":185,"officialTitle":186,"acronym":4,"eligibilityCriteria":187,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":188,"enrollmentInfo":189,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":191,"conditions":192,"keywords":196,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":201,"lastUpdatePostDateStruct":202,"startDateStruct":204,"completionDateStruct":206,"leadSponsor":208,"locationsCount":39},"100619170","blood-storage-related-mortality-and-adverse-effects-in-trauma-patients-100619170","NCT07341139","Blood Storage Related Mortality and Adverse Effects in Trauma Patients","Is Long-Term Blood Storage Related With Increased Mortality and Adverse Effects in Severely Injured Trauma Patients?","Inclusion Criteria:\n\n* Patients between 18-75 years of age,\n* Injury Severity Score\\>15 and have received massive blood transfusions in our hospital from 1 January 2015 to 31 December 2025\n* The patients admitted because of trauma and undergoing surgery\n\nExclusion Criteria:\n\n* Patients with known cardiac or vascular diseases such as heart failure or malignant hypertension, those under anticoagulant treatment\n* Patients with known serious kidney (on dialysis), lung, liver diseases, those under anticoagulant treatment\n* Super obese patients with body mass index (BMI) 50 or above","75 Years",{"count":190,"type":21},300,"The purpose of this retrospective study is to examine the following factors related to blood storage time in severely injured trauma patients who received large blood transfusions:\n\n1. The effect of blood storage time on the patient's 28-day mortality rate.\n2. The relationship between storage time and other health problems that the patient may develop (such as heart disease, vascular occlusion, respiratory failure, infection, and organ failure).\n\nFor this purpose, patients aged 18-75 who were admitted directly from the scene of injury and received large transfusions at Jacksonville Shands Hospital between January 1, 2023, and October 1, 2025, will be included. Data will be obtained from hospital information systems and anesthesia records",[193,194,195],"Transfusion Adverse Reaction","Major Trauma","Blood Product Transfusion for All Conditions",[197,198,199,200],"blood storage","Transfusion","Trauma","Red Blood Cell","2026-02-12",{"date":203,"type":31},"2026-02-17",{"date":205,"type":31},"2026-01-17",{"date":207,"type":21},"2026-06-01",{"name":37,"class":38},{"id":210,"slug":211,"hasResults":11,"nctId":212,"briefTitle":213,"officialTitle":214,"acronym":4,"eligibilityCriteria":215,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":216,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":218,"conditions":219,"keywords":226,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":232,"lastUpdatePostDateStruct":233,"startDateStruct":235,"completionDateStruct":237,"leadSponsor":239,"locationsCount":39},"100612666","machine-learning-for-predicting-spinal-anesthesia-duration-100612666","NCT07256548","Machine Learning for Predicting Spinal Anesthesia Duration","Comparative Evaluation of Machine Learning Algorithms for Predicting Spinal Anesthesia Termination Time","Inclusion Criteria:\n\n1. Patients scheduled to undergo total knee arthroplasty between November 2025 and March 2026 at the Kocaeli City Hospital Operating Theaters.\n2. Patients who have provided written informed consent to participate in the study.\n3. Patients whose surgery is planned under spinal anesthesia.\n4. Patients for whom complete clinical data can be obtained during the study period.\n5. Adults aged 18 years or older, classified as American Society of Anesthesiologist's (ASA) Physical Status I or II.\n\nExclusion Criteria:\n\n1. Patients who were converted to general anesthesia during surgery or initially operated under general anesthesia.\n2. Patients who required postoperative intensive care unit (ICU) admission following anesthesia.\n3. Patients who developed surgical complications and for whom postoperative mobilization could not be planned.\n4. Patients with cognitive impairment preventing them from completing pain assessment scales in the postoperative period.\n5. Patients with neuropathic pain, multiple sclerosis, or other neuromotor disorders will be excluded from the study.",{"count":217,"type":21},140,"Spinal anesthesia provides significant advantages over general anesthesia in knee arthroplasty, including reduced blood loss, faster recovery, and fewer complications. However, predicting its duration is critical for patient safety and effective postoperative management. This study evaluates the usability of machine learning (ML) algorithms to predict the termination time of spinal anesthesia and the patient's readiness for mobilization. Using demographic, surgical, and anesthetic variables, ML models were trained to estimate anesthesia duration. Accurate predictions may improve intraoperative planning, optimize postoperative care, and enhance patient outcomes. Integrating ML-based predictive systems into anesthesia practice can contribute to safer, more efficient, and personalized perioperative management.",[220,221,222,223,224,225],"Spinal Anesthesia","Machine Learning","Knee Arthroplasty, Total","Spinal Anesthesia Duration","Postoperative Care","Postoperative Acute Pain",[227,228,229,230,231],"spinal anesthesia","machine learning","Knee arthroplasty","spinal anesthesia duration","Acute postoperative pain","2025-12-01",{"date":234,"type":31},"2025-12-08",{"date":236,"type":31},"2025-10-31",{"date":238,"type":21},"2026-03-01",{"name":37,"class":38},{"id":241,"slug":242,"hasResults":11,"nctId":243,"briefTitle":244,"officialTitle":245,"acronym":4,"eligibilityCriteria":246,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":247,"targetDuration":249,"studyType":22,"phases":4,"briefSummary":250,"conditions":251,"keywords":255,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":259,"lastUpdatePostDateStruct":260,"startDateStruct":262,"completionDateStruct":264,"leadSponsor":266,"locationsCount":39},"100573796","the-impact-of-propofol-and-ketamine-on-cardiovascular-collapse-during-induction-for-intubation-100573796","NCT06750939","The Impact of Propofol and Ketamine on Cardiovascular Collapse During Induction for Intubation","The Impact of Propofol and Ketamine on Cardiovascular Collapse During Induction for Endotracheal Intubation in Critically Ill Patients: A Prospective Observational Study","Inclusion Criteria:\n\n* Patients aged over 18 years\n* Patients admitted to the intensive care unit (ICU) who undergo endotracheal intubation during their ICU stay will be included.\n\nExclusion Criteria:\n\n* Patients who did not provide consent to participate in the study\n* Patients intubated due to cardiac arrest\n* Patients intubated outside the intensive care unit",{"count":248,"type":21},128,"30 Days","This prospective observational study evaluates the impact of propofol and ketamine on the risk of cardiovascular collapse during induction for endotracheal intubation in critically ill patients. Induction agents play a crucial role in managing hemodynamic stability, particularly in this vulnerable population. Propofol, known for its vasodilatory and myocardial depressant effects, has been associated with significant hypotension during induction. Conversely, ketamine, with its sympathomimetic properties, is often considered a safer alternative for hemodynamic stability.\n\nIn addition to comparing the incidence of cardiovascular collapse-defined as severe hypotension or cardiac arrest-this study examines the relationship between these induction agents and shock indices, including systolic shock index, diastolic shock index, age-adjusted shock index, and modified shock index. These parameters will provide a more detailed understanding of the hemodynamic effects of each agent and their clinical implications. The findings aim to guide induction agent selection to optimize outcomes in critically ill patients.",[252,253,254],"Cardiovascular Collapse","Intubation Complication","Anaesthetic Complication Cardiac",[256,257,258],"cardiac arrest","intubation","shock index","2025-09-16",{"date":261,"type":31},"2025-09-22",{"date":263,"type":31},"2024-07-15",{"date":265,"type":21},"2025-11-01",{"name":37,"class":38},{"id":268,"slug":269,"hasResults":11,"nctId":270,"briefTitle":271,"officialTitle":271,"acronym":4,"eligibilityCriteria":272,"healthyVolunteers":48,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":273,"targetDuration":4,"studyType":108,"phases":275,"briefSummary":277,"conditions":278,"keywords":281,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":287,"lastUpdatePostDateStruct":288,"startDateStruct":290,"completionDateStruct":292,"leadSponsor":294,"locationsCount":39},"100602466","phase-4-effect-of-combined-intravenous-inhalational-anesthesia-civia-on-postoperative-recovery-patterns-100602466","NCT07123870","Effect of Combined Intravenous-Inhalational Anesthesia (CIVIA) on Postoperative Recovery Patterns.","Inclusion Criteria:\n\n* Scheduled for spine surgery\n* Expected surgery duration longer than 3 hours\n* Use of intraoperative neuromonitoring\n* BIS-guided anesthesia administered\n* TIVA (with TCI) as the primary anesthetic technique\n* Age \\>18 years\n\nExclusion Criteria:\n\n* Emergency surgeries\n* Patients receiving sole inhaled anesthesia (no TIVA)\n* Perioperative dural injury\n* Intraoperative severe hypotension requiring inotropic support\n* Hypothermia (based on temperature measured before recovery)",{"count":274,"type":21},210,[276],"PHASE4","This study was planned as a single-center, prospective, randomized trial. Adult patients undergoing elective spinal surgery lasting longer than three hours, performed in a neurosurgery operating room, will be evaluated. Patients managed with three different anesthesia methods currently used will be examined for recovery patterns:\n\n1. Total intravenous anesthesia (TIVA),\n2. TIVA Combined anesthesia with sevoflurane and intravenous agents (sevoflurane-CIVIA),\n3. TIVA Combined anesthesia with desflurane and intravenous agents (desflurane-CIVIA).\n\nRecovery patterns include; extubation time, eye opening time, emergence agitation, postoperative nausia and vomiting and postoperative recovery unit discharge time.",[25,279,280],"Inhalation Anesthesia","Total Intravenous Anesthesia",[282,283,284,285,286],"CIVIA","TIVA","sevoflurane","desflurane","postoperative recovery","2025-08-08",{"date":289,"type":31},"2025-08-14",{"date":291,"type":31},"2025-07-23",{"date":293,"type":21},"2025-11-15",{"name":37,"class":38},{"id":296,"slug":297,"hasResults":11,"nctId":298,"briefTitle":299,"officialTitle":300,"acronym":4,"eligibilityCriteria":301,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":302,"targetDuration":52,"studyType":22,"phases":4,"briefSummary":304,"conditions":305,"keywords":308,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":311,"lastUpdatePostDateStruct":312,"startDateStruct":314,"completionDateStruct":316,"leadSponsor":318,"locationsCount":39},"100595435","the-effect-of-cognitive-function-level-in-morbidly-obese-patients-100595435","NCT07032415","The Effect of Cognitive Function Level in Morbidly Obese Patients","The Effect of a Nutrition Habit Change Program on Lifestyle and Cognitive Function Level in Morbidly Obese Patients","Inclusion Criteria:\n\n* Applying Kocaeli City Hospital's Obesity Center\n* Morbid Obesity\n* Completing the program\n\nExclusion Criteria:\n\n* People with psychiatric and neurological diseases\n* People using drugs",{"count":303,"type":21},77,"Obesity is a disease caused by many factors, such as lifestyle, eating habits, lack of physical activity, hormonal and genetic influences. These different factors make treatment planning difficult. Common treatments include changes in diet and lifestyle, medications, endoscopic methods (like balloon or botox), and surgery. No matter which method is used, the main goal is to help patients lose weight by creating a negative energy balance. To keep the weight off, patients need to maintain a balanced lifestyle in the long term.\n\nHowever, many treatments are not successful over time. One important part of long-term success is helping patients change their lifestyle and eating habits. A person's cognitive function may affect how they understand and follow these changes. Some studies show that a high body mass index (BMI) is linked to problems with thinking and memory. While weight loss may help improve brain function, the investigators don't yet know how early cognitive differences affect treatment results.\n\nAt the obesity center in our hospital, morbidly obese patients receive support from a team of doctors, dietitians, psychologists, and physiotherapists. For at least three months, they attend individual and group sessions to help change their lifestyle and eating habits. This study aims to see how patients' cognitive function affects how much weight they lose by the end of the program.",[306,307],"Obesity","Morbid Obesity",[309,310],"bariatric surgery","cognition","2025-06-25",{"date":313,"type":31},"2025-06-29",{"date":315,"type":21},"2025-07-22",{"date":317,"type":21},"2026-09-15",{"name":37,"class":38},{"id":320,"slug":321,"hasResults":11,"nctId":322,"briefTitle":323,"officialTitle":324,"acronym":4,"eligibilityCriteria":325,"healthyVolunteers":48,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":326,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":328,"conditions":329,"keywords":333,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":336,"lastUpdatePostDateStruct":337,"startDateStruct":339,"completionDateStruct":341,"leadSponsor":343,"locationsCount":39},"100576947","effect-of-mechanical-ventilation-on-radiofrequency-ablation-in-atrial-fibrillation-100576947","NCT06791915","Effect of Mechanical Ventilation on Radiofrequency Ablation in Atrial Fibrillation","The Effect of Mechanical Ventilation on Radiofrequency Ablation in The Treatment of Atrial Fibrillation.","Inclusion Criteria:\n\n* Diagnosed with atrial fibrillation\n* planned to receive radiofrequency ablation treatment under general anesthesia\n* all patients over 18 years of age\n\nExclusion Criteria:\n\n\\- Patients undergoing ablation under sedation and\u002For local anesthesia",{"count":327,"type":21},50,"Radiofrequency ablation (RFA) for atrial fibrillation (AF) is performed under general anesthesia. The success of the procedure depends on the safe contact of the catheter electrode with the myocardium. Movement of the catheter tip due to respiratory changes can result in inadequate lesion formation and AF recurrence.\n\nThe success of AF ablation depends on the adequacy of energy delivered to the myocardium and the durability of pulmonary vein isolation (PVI). Poor energy delivery and tissue heating during ablation are a major cause of procedural failure in RFA. To improve the success of the PVI procedure, efforts are underway to optimize catheter stability and contact force. However, catheter force and stability are influenced by respiration-induced thoracic motion, highlighting the importance of controlled breathing for further optimization. Fluoroscopy and ablation times during electroanatomic mapping-guided AF ablations improved with controlled mechanical ventilation. General anesthesia improved catheter contact.\n\nLow tidal volume, high respiratory rate (FCV), pressure controlled mechanical ventilation (PCV), volume controlled mechanical ventilation (VCV), pressure controlled volume assured mechanical ventilation (PRVC) can be used in investigators' hospital. The literature offers no definitive proof that one ablation procedure is superior to another.",[330,331,332],"Radiofrequency Ablation","Atrial Fibrillation","Mechanical Ventilation",[331,334,335],"Ablation","general anesthesia","2025-01-23",{"date":338,"type":31},"2025-01-24",{"date":340,"type":31},"2025-01-01",{"date":342,"type":21},"2025-08-01",{"name":37,"class":38},{"id":345,"slug":346,"hasResults":11,"nctId":347,"briefTitle":348,"officialTitle":348,"acronym":4,"eligibilityCriteria":349,"healthyVolunteers":48,"sex":17,"minAge":18,"maxAge":350,"enrollmentInfo":351,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":353,"conditions":354,"keywords":359,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":364,"lastUpdatePostDateStruct":365,"startDateStruct":367,"completionDateStruct":369,"leadSponsor":371,"locationsCount":39},"100557824","evaluation-of-the-relationship-between-perioperative-hypothermia-and-emergence-agitation-100557824","NCT06543134","Evaluation of The Relationship Between Perioperative Hypothermia and Emergence Agitation","Inclusion Criteria:\n\n* Patients with informed consent Elective planned cases\n* Patients between the ages of 18-65\n* American Society of Anesthesiologists ASA classification ASA 1-2 patients\n* Surgeries planned to last at least 30 minutes.\n\nExclusion Criteria:\n\n* Patients who refuse to participate in the study,\n* patients who are considered for emergency surgery,\n* pediatric patients,\n* patients with peripheral vascular diseases or carotid stenosis,\n* patients using antidepressants or antipsychotic drugs\n* those with neurological diseases will be excluded from the study.","65 Years",{"count":352,"type":21},120,"The main aim of our study was to investigate the relationship between perioperative hypothermia and postoperative emergence agitation.",[355,356,357,358],"Hypothermia; Anesthesia","Agitation, Emergence","Postoperative Complications","Hypothermia Following Anesthesia",[360,361,362,363,357],"Hypothermia","Agitation","Emergence","Recovery from anesthesia","2024-08-03",{"date":366,"type":31},"2024-08-07",{"date":368,"type":31},"2024-03-01",{"date":370,"type":21},"2024-09-15",{"name":37,"class":38},{"id":373,"slug":374,"hasResults":11,"nctId":375,"briefTitle":376,"officialTitle":377,"acronym":4,"eligibilityCriteria":378,"healthyVolunteers":48,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":379,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":381,"conditions":382,"keywords":4,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":384,"lastUpdatePostDateStruct":385,"startDateStruct":387,"completionDateStruct":389,"leadSponsor":391,"locationsCount":4},"100553827","increase-residents-confidence-in-emergency-front-of-neck-access-efona-100553827","NCT06491147","Increase Residents' Confidence in Emergency Front of Neck Access (eFONA).","A Simple Model to Increase Residents' Confidence in Emergency Front of Neck Access (eFONA).","Inclusion Criteria:\n\n* Working as an assistant doctor in Kocaeli City Hospital Anesthesiology and Reanimation Clinic\n\nExclusion Criteria:\n\n* Those who have previously received training on FONA",{"count":380,"type":21},40,"Emergency front of neck access (eFONA) in a non-ventilated, non-oxygenated (CVCO) patient scenario is a life-saving and important competency for anesthesiologists to learn and even repeat intermittently. The Difficult Airway Society (DAS) guideline does not elaborate on how to conduct eFONA training, while the Canadian guideline states that successful performance of such rarely used skills requires regular practice in a simulation environment that focuses on technique and provides expert feedback. In this guideline, it was also mentioned that during training, procedures can be repeatedly performed in a simulate environment and interrupted for immediate feedback. In line with these recommendations, the investigators will create an easy, inexpensive, feasible and repeatable simulation-based learning environment in the operating room of the hospital. In this model study, it is aimed to teach the cricothyrotomy technique to anesthesiologists who have no experience in eFONA with an easy set up and to increase the confidence of the participants in this subject.",[383],"Unexpected Difficult Airway","2024-07-03",{"date":386,"type":31},"2024-07-08",{"date":388,"type":21},"2024-06-30",{"date":390,"type":21},"2024-12-31",{"name":37,"class":38},{"id":393,"slug":394,"hasResults":11,"nctId":395,"briefTitle":396,"officialTitle":396,"acronym":4,"eligibilityCriteria":397,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":350,"enrollmentInfo":398,"targetDuration":400,"studyType":22,"phases":4,"briefSummary":401,"conditions":402,"keywords":405,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":407,"lastUpdatePostDateStruct":408,"startDateStruct":410,"completionDateStruct":412,"leadSponsor":414,"locationsCount":39},"100550495","changes-in-difficult-airway-markers-after-surgery-for-obstructive-sleep-apnoea-syndrome-100550495","NCT06447818","Changes in Difficult Airway Markers After Surgery for Obstructive Sleep Apnoea Syndrome","Inclusion Criteria:\n\n* Age between 18-65\n* American society of assosication score (ASA) :1-3\n* To undergo Obstructive sleep apnea surgery (OSAS)\n\nExclusion Criteria:\n\n* Verbal and written consent cannot be obtained",{"count":399,"type":21},42,"1 Year","This study investigates the changes in difficult airway markers at 6 months post operatively in patients undergoing obstructive sleep apnoea surgery",[403,404],"Obstructive Sleep Apnea of Adult","Difficult or Failed Intubation",[406],"Obstructive sleep apnea surgery, Difficult airway markers","2024-06-03",{"date":409,"type":31},"2024-06-07",{"date":411,"type":31},"2024-05-15",{"date":413,"type":21},"2025-05-15",{"name":37,"class":38},""]