[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Kocaeli University\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":646},{"pageToken":4,"total":5,"offset":6,"count":7,"results":8},null,32,0,25,[9,50,74,101,124,150,179,203,232,256,277,317,342,370,396,415,434,454,478,502,530,556,577,598,622],{"id":10,"slug":11,"hasResults":12,"nctId":13,"briefTitle":14,"officialTitle":15,"acronym":4,"eligibilityCriteria":16,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":31,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":44,"leadSponsor":46,"locationsCount":49},"100644112","effect-of-ai-assisted-respiratory-training-on-pain-fatigue-and-respiratory-parameters-in-patients-after-open-heart-surgery-100644112",false,"NCT07665593","Effect of AI-Assisted Respiratory Training on Pain, Fatigue and Respiratory Parameters in Patients After Open Heart Surgery","The Effect of Artificial Intelligence-Assisted Respiratory Training on Pain, Fatigue and Respiratory Parameters in Patients After Open Heart Surgery","Inclusion Criteria:\n\n* Patients undergoing elective open heart surgery.\n* Conscious.\n* Speaks and understands Turkish.\n* Has a chest tube inserted (on the right and\u002For left side).\n* No visual, auditory, or mental problems.\n* Willing to participate in the study.\n\nExclusion Criteria:\n\n* Undergoing concurrent other chest surgery or having a history of re-surgery.\n* Development of early postoperative complications (e.g., atelectasis) within 0-3 days.\n* Any loss of an extremity.\n* Long-term immobilization and intubation.\n* Development of severe post-surgery infections (such as mediastinitis or sepsis) or respiratory complications (such as pneumonia or atelectasis).","ALL","18 Years",{"count":20,"type":21},111,"ESTIMATED","INTERVENTIONAL",[24],"NA","This randomized controlled study aims to evaluate the effect of artificial intelligence (AI)-assisted respiratory training on fatigue, pain, and respiratory parameters in patients after open heart surgery.",[27,28,29,30],"Nursing Care","Pain","Breathing Exercises","Fatigue Recovery",[32,33,34,35,36],"pain","nursing care","fatigue","breathing exercises","open heart surgery","RECRUITING","2026-06-22",{"date":40,"type":41},"2026-06-24","ACTUAL",{"date":43,"type":41},"2026-02-10",{"date":45,"type":21},"2026-10",{"name":47,"class":48},"Kocaeli University","OTHER",1,{"id":51,"slug":52,"hasResults":12,"nctId":53,"briefTitle":54,"officialTitle":54,"acronym":4,"eligibilityCriteria":55,"healthyVolunteers":56,"sex":57,"minAge":58,"maxAge":59,"enrollmentInfo":4,"targetDuration":4,"studyType":60,"phases":4,"briefSummary":61,"conditions":62,"keywords":64,"overallStatus":68,"whyStopped":4,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":4,"completionDateStruct":4,"leadSponsor":72,"locationsCount":73},"100574316","evaluation-of-different-serum-cartilage-biomarkers-in-the-acute-response-to-walking-and-cycling-in-healthy-male-subjects-100574316","NCT06757699","Evaluation of Different Serum Cartilage Biomarkers in the Acute Response to Walking and Cycling in Healthy Male Subjects","Inclusion Criteria:\n\n* Healthy male volunteers between the ages of 20-35\n* Those who do physical activity for at least 30 minutes two to three days a week\n* 17 healthy male individuals without any health problems will be included.\n\nExclusion Criteria:\n\n* Those with acute or chronic injuries in their lower extremities\n* Those with musculoskeletal disorders in their lower extremities\n* Those who have undergone hip and\u002For knee surgery\n* Those with cardio-pulmonary problems that prevent them from exercising",true,"MALE","20 Years","35 Years","EXPANDED_ACCESS","The effect of physical activity on serum cartilage biomarkers is largely unknown. This study is critical to increase our knowledge of the physiological cartilage response to activities of daily living and dynamic tasks by focusing on healthy recreationally active individuals, thus improving our understanding of the complex relationship between cartilage health and the loading that occurs during different types of loading.",[63],"Biochemical Markers",[65,66,67],"serum cartilage","Osteoblastic activity","Osteoclastic activity","AVAILABLE","2026-06-08",{"date":71,"type":41},"2026-06-10",{"name":47,"class":48},2,{"id":75,"slug":76,"hasResults":12,"nctId":77,"briefTitle":78,"officialTitle":79,"acronym":80,"eligibilityCriteria":81,"healthyVolunteers":56,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":82,"targetDuration":4,"studyType":22,"phases":84,"briefSummary":85,"conditions":86,"keywords":88,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":93,"lastUpdatePostDateStruct":94,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":100,"locationsCount":49},"100637403","upper-extremity-exercises-with-and-without-deep-breathing-after-cardiac-surgery-100637403","NCT07627009","Upper Extremity Exercises With and Without Deep Breathing After Cardiac Surgery","Evaluation of the Effects of Upper Extremity Range of Motion Exercises Performed With and Without Deep Breathing on Respiratory Parameters After Cardiac Surgery: A Randomized Trials","ROM-DB","Inclusion Criteria:\n\n* underwent elective open-heart surgery,\n* stayed in the cardiovascular ICU for at least 2 nights post-operatively,\n* had FiO2 below 40% (Spo2 will be kept above 92),\n* were conscious,\n* could speak Turkish,\n* were willing to participate in the study.\n\nExclusion Criteria:\n\nunderwent another thoracic surgery or repeat surgery simultaneously,\n\n* had any limb loss,\n* underwent prolonged immobilization and intubation,\n* developed serious complications such as infection or respiratory failure after surgery,\n* had problems such as paresthesia, plegia, etc. after stroke, or had diseases such as Parkinson's that affect the level of relaxa",{"count":83,"type":21},90,[24],"This randomized 2×2 crossover trial aims to evaluate the effects of upper extremity range of motion exercises performed with and without deep breathing on respiratory parameters in patients after open cardiac surgery. The study will include adult patients who underwent elective open cardiac surgery and are receiving postoperative care in the cardiovascular surgery intensive care unit. Each participant will perform both exercise protocols: upper extremity range of motion exercises alone and upper extremity range of motion exercises combined with deep breathing. The order of the two interventions will be randomized. Respiratory and clinical outcomes, including oxygen saturation, tidal volume, respiratory rate, heart rate, pain, perceived exertion, and dyspnea, will be assessed before and after each intervention.",[87],"Cardiac Surgery",[89,90,91,92],"Cardiac surgery","Range of motion exercise","Deep breathing exercise","Postoperative respiratory function","2026-05-30",{"date":95,"type":41},"2026-06-04",{"date":97,"type":41},"2025-09-01",{"date":99,"type":21},"2026-09-30",{"name":47,"class":48},{"id":102,"slug":103,"hasResults":12,"nctId":104,"briefTitle":105,"officialTitle":105,"acronym":4,"eligibilityCriteria":106,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":107,"enrollmentInfo":108,"targetDuration":4,"studyType":22,"phases":110,"briefSummary":111,"conditions":112,"keywords":4,"overallStatus":115,"whyStopped":4,"lastUpdateSubmitDate":116,"lastUpdatePostDateStruct":117,"startDateStruct":119,"completionDateStruct":121,"leadSponsor":123,"locationsCount":4},"100637228","hfnc-versus-microstream-advance-nasal-cannula-for-oxygenation-during-ercp-100637228","NCT07611903","HFNC Versus Microstream Advance Nasal Cannula for Oxygenation During ERCP","Inclusion Criteria:\n\n* Patients aged 18 to 84 years\n* ASA physical status I-III\n* Patients scheduled to undergo ERCP\n* Patients who provide written informed consent\n\nExclusion Criteria:\n\n* Recent history of upper respiratory tract infection\n* History of lung cancer\n* Chronic obstructive pulmonary disease\n* Asthma\n* Body mass index greater than 35 kg\u002Fm²\n* Refusal to participate in the study","84 Years",{"count":109,"type":21},74,[24],"Endoscopic retrograde cholangiopancreatography (ERCP) procedures are commonly performed under deep sedation and are associated with a risk of hypoxemia, particularly in prone or semi-prone positions. High-flow nasal cannula (HFNC) therapy may improve oxygenation by delivering heated and humidified oxygen at high flow rates, while the Microstream Advance nasal cannula provides simultaneous nasal oxygen delivery and oral oxygen insufflation.\n\nThis prospective randomized study aims to compare the effectiveness of HFNC and Microstream Advance nasal cannula in maintaining oxygenation during ERCP procedures. Patients undergoing ERCP will be randomized into two groups receiving either HFNC or Microstream Advance nasal cannula oxygen support during sedation.\n\nThe primary outcomes are the incidence of desaturation and oxygen reserve index (ORi) measurements during the procedure. Secondary outcomes include time to achieve target ORi levels, respiratory complications, and procedure-related adverse events.",[113,114],"Endoscopic Retrograde Cholangiopancreatography","Hypoxemia","NOT_YET_RECRUITING","2026-05-28",{"date":118,"type":41},"2026-06-01",{"date":120,"type":21},"2026-06-29",{"date":122,"type":21},"2026-12-30",{"name":47,"class":48},{"id":125,"slug":126,"hasResults":12,"nctId":127,"briefTitle":128,"officialTitle":129,"acronym":4,"eligibilityCriteria":130,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":131,"enrollmentInfo":132,"targetDuration":4,"studyType":22,"phases":134,"briefSummary":135,"conditions":136,"keywords":138,"overallStatus":115,"whyStopped":4,"lastUpdateSubmitDate":143,"lastUpdatePostDateStruct":144,"startDateStruct":146,"completionDateStruct":147,"leadSponsor":149,"locationsCount":49},"100630055","electromyographic-biofeedback-therapy-in-patients-with-dyssynergic-defecation-100630055","NCT07482696","Electromyographic Biofeedback Therapy in Patients With Dyssynergic Defecation","Effects of Game-Based Electromyographic Biofeedback Therapy on Quality of Life and Sleep Quality in Patients With Dyssynergic Defecation","Inclusion Criteria:\n\n1. Diagnosis of dyssynergic defecation was confirmed by anorectal manometry, which demonstrated paradoxical pelvic floor muscle contraction and\u002For inadequate relaxation during defecation.\n2. Eligibility for a pelvic floor rehabilitation program was based on a comprehensive evaluation conducted at the Physical Medicine and Rehabilitation Clinic.\n3. Age between 18 and 70 years.\n4. A history of chronic constipation lasting at least six months, in accordance with the Rome IV diagnostic criteria.\n5. Stool consistency was classified as type 1 or type 2 according to the Bristol Stool Scale, indicating a hard stool pattern.\n\nExclusion Criteria:\n\n1. Presence of communication barriers that may interfere with participation in the study.\n2. Cognitive impairment affects the ability to comply with rehabilitation programs or assessments.\n3. Pregnancy.\n4. Presence of severe depression and\u002For anxiety disorder.\n5. Untreated metabolic or endocrine disorders, including but not limited to diabetes mellitus, hypothyroidism, hypokalemia, and hypercalcemia.\n6. Use of medications known to cause or exacerbate constipation.\n7. History of spinal, rectal, or pelvic surgery, excluding cholecystectomy, hysterectomy, and appendectomy.\n8. Presence of colorectal malignancy or inflammatory bowel disease.\n9. Anorectal malformations or congenital pelvic floor anomalies.\n10. Spina bifida, spinal cord injury, or neurological disorders, including multiple sclerosis, Parkinson's disease, dementia, or epilepsy.\n11. Presence of severe cardiac or renal disease.\n12. Advanced-stage hemorrhoids, anal fissures, or anal fistulas.","70 Years",{"count":133,"type":21},36,[24],"This study aimed to investigate the effects of game-based electromyographic (EMG) biofeedback therapy on the quality of life and sleep quality of individuals diagnosed with dyssynergic defecation.",[137],"Defecation Disorder",[139,140,141,142],"Dyssynergic Defecation","Electromyographic Biofeedback","Pelvic Floor Rehabilitation","Constipation","2026-03-31",{"date":145,"type":41},"2026-04-06",{"date":143,"type":21},{"date":148,"type":21},"2026-12-31",{"name":47,"class":48},{"id":151,"slug":152,"hasResults":12,"nctId":153,"briefTitle":154,"officialTitle":155,"acronym":4,"eligibilityCriteria":156,"healthyVolunteers":12,"sex":157,"minAge":18,"maxAge":158,"enrollmentInfo":159,"targetDuration":4,"studyType":161,"phases":4,"briefSummary":162,"conditions":163,"keywords":165,"overallStatus":115,"whyStopped":4,"lastUpdateSubmitDate":171,"lastUpdatePostDateStruct":172,"startDateStruct":174,"completionDateStruct":176,"leadSponsor":178,"locationsCount":49},"100631228","optic-nerve-sheath-diameter-for-predicting-post-dural-puncture-headache-in-cesarean-section-patients-100631228","NCT07497945","Optic Nerve Sheath Diameter for Predicting Post-Dural Puncture Headache in Cesarean Section Patients","Evaluation of Optic Nerve Sheath Diameter for Predicting Post-Dural Puncture Headache in Cesarean Section Patients: A Prospective Observational Study","Inclusion Criteria:\n\n* Women aged 18 to 45 years\n* Singleton pregnancy\n* Planned cesarean section (elective or emergency due to fetal indications)\n* Spinal anesthesia planned for the procedure\n* American Society of Anesthesiologists (ASA) physical status II-III\n* Normal coagulation parameters (INR less than 1.5, platelet count greater than 100,000\u002Fmm³)\n* Ability to provide written informed consent and cooperate with study procedures\n\nExclusion Criteria:\n\n* Known ophthalmologic diseases affecting the optic nerve or retina (e.g., glaucoma, optic atrophy)\n* Active eye infection or recent ocular surgery\n* Known intracranial pathology affecting cerebrospinal fluid dynamics (e.g., intracranial mass, hydrocephalus, idiopathic intracranial hypertension)\n* History of stroke or subarachnoid hemorrhage\n* Hypertensive disorders of pregnancy such as preeclampsia or eclampsia\n* Contraindications to spinal anesthesia (e.g., coagulopathy, anticoagulant therapy, infection at puncture site)\n* Allergy to local anesthetics\n* Conversion to general anesthesia due to failed or inadequate spinal block\n* Presence of moderate or severe preoperative headache or active primary headache disorders such as migraine","FEMALE","45 Years",{"count":160,"type":21},220,"OBSERVATIONAL","Some patients develop headache after spinal anesthesia used during cesarean section. This condition is called post-dural puncture headache (PDPH). Early identification of patients at risk may improve patient care.\n\nThis study evaluates whether optic nerve sheath diameter (ONSD), measured using a non-invasive bedside ocular ultrasound technique, can help predict the development of PDPH.\n\nParticipants undergoing cesarean section with spinal anesthesia will undergo ONSD measurements at predefined perioperative time points. Participants will be followed postoperatively for the occurrence of headache.\n\nThe findings may help improve early recognition and management of PDPH.",[164],"Post Dural Puncture Headache",[166,167,168,169,170],"Optic Nerve Sheath Diameter","Cesarean Section","Spinal Anesthesia","Obstetric Anesthesia","Ocular Ultrasound","2026-03-23",{"date":173,"type":41},"2026-03-27",{"date":175,"type":21},"2026-03-20",{"date":177,"type":21},"2027-03-31",{"name":47,"class":48},{"id":180,"slug":181,"hasResults":12,"nctId":182,"briefTitle":183,"officialTitle":184,"acronym":4,"eligibilityCriteria":185,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":186,"enrollmentInfo":187,"targetDuration":4,"studyType":161,"phases":4,"briefSummary":188,"conditions":189,"keywords":193,"overallStatus":115,"whyStopped":4,"lastUpdateSubmitDate":195,"lastUpdatePostDateStruct":196,"startDateStruct":198,"completionDateStruct":200,"leadSponsor":202,"locationsCount":73},"100630124","baseline-gastric-volume-in-diabetic-vs-non-diabetic-patients-100630124","NCT07483593","Baseline Gastric Volume in Diabetic vs Non-Diabetic Patients","Baseline Gastric Volume Measurement in Diabetic and Non-Diabetic Patients: A Non-Inferiority Study","Inclusion Criteria:\n\n* Ages 18-75\n* ASA I-III\n* BMI ≤ 40 kg\u002Fm2\n\nExclusion Criteria:\n\n* Patients with a history of gastrointestinal surgery,\n* Pregnant women,\n* Patients with documented abnormalities in the upper gastrointestinal tract, such as achalasia","75 Years",{"count":160,"type":21},"During the preoperative preparation process, the fasting period for anesthesia is planned according to guidelines. According to standard guidelines, a fasting period of at least 2 hours is recommended for clear liquids, at least 6 hours for light meals, and at least 8 hours for a full meal. However, it has been reported that these guidelines are valid for healthy patients. It is thought that the planned fasting periods may vary in diabetic patients due to delayed gastric emptying. This study aims to calculate gastric volume under ultrasonography guidance and compare it with fasting time.",[190,191,192],"Gastric Volume","Preoperative Fasting","Diabetes Mellitus",[194,190,192],"Gastric Ultrasound","2026-03-16",{"date":197,"type":41},"2026-03-19",{"date":199,"type":21},"2026-04-20",{"date":201,"type":21},"2026-11-15",{"name":47,"class":48},{"id":204,"slug":205,"hasResults":12,"nctId":206,"briefTitle":207,"officialTitle":208,"acronym":209,"eligibilityCriteria":210,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":211,"enrollmentInfo":212,"targetDuration":4,"studyType":22,"phases":214,"briefSummary":215,"conditions":216,"keywords":219,"overallStatus":115,"whyStopped":4,"lastUpdateSubmitDate":225,"lastUpdatePostDateStruct":226,"startDateStruct":228,"completionDateStruct":230,"leadSponsor":231,"locationsCount":4},"100627764","community-based-occupational-therapy-for-syrian-refugees-to-improve-social-participation-and-occupational-justice-100627764","NCT07452874","Community-Based Occupational Therapy for Syrian Refugees to Improve Social Participation and Occupational Justice","The Effect of a Community-Based Occupational Therapy Intervention on Occupational Justice and Social Participation in Syrian Refugees: A Non-Invasive Clinical Study","COT-SYR-25","Inclusion Criteria:\n\n* Being a Syrian refugee,\n* Being 18 years of age or older,\n* Having sufficient Turkish language proficiency to communicate effectively,\n* Willingness to participate in the study voluntarily and providing written informed consent.\n\nExclusion Criteria:\n\n* Inability to communicate in Turkish,\n* Presence of a cognitive or neurological condition that may interfere with communication or participation in the assessment\n* Presence of a serious health condition that may prevent regular attendance at the intervention or educational sessions.","65 Years",{"count":213,"type":21},16,[24],"This study aims to examine the effects of a community-based occupational therapy intervention on occupational justice, participation in daily life activities, occupational performance, satisfaction, and overall functioning among Syrian refugees living in Turkey. Refugees frequently encounter social, economic, and environmental barriers that restrict their engagement in meaningful daily activities and negatively affect their sense of autonomy, belonging, and participation. Addressing these complex challenges requires interventions that extend beyond individual skill development and actively target social participation, access to community resources, and justice in everyday occupations.\n\nIn this study, a structured community-based occupational therapy intervention has been developed based on the Participatory Occupational Justice Framework. The intervention is designed to enhance participants' access to community resources, support engagement in meaningful daily activities, strengthen social participation, and promote empowerment and self-determination. The program consists of group-based, activity-oriented sessions implemented within real-life community settings to facilitate contextualized learning and participation.\n\nA total of 16 adult Syrian refugees are planned to be enrolled in the study and assigned to either an intervention group or a control group using a parallel-group design. Participants in the intervention group will receive a five-week community-based occupational therapy program comprising ten structured sessions. Participants in the control group will receive a single informational session focusing on daily life and available services in Turkey. Outcomes will be assessed at baseline and immediately after the intervention using standardized measures of occupational justice, occupational performance and satisfaction, participation in daily activities, and overall functioning.\n\nThe findings of this study are expected to provide evidence regarding the effectiveness of community-based occupational therapy interventions in promoting occupational justice, participation, and functional well-being among refugee populations. The results are also anticipated to contribute to the development of rights-based, inclusive, and participation-focused rehabilitation practices for forcibly displaced communities.",[217,218],"Refugees","Occupational Injustice",[220,217,221,222,223,224],"Community-based occupational therapy","Occupational justice","Social participation","Occupational performance","Participatory Occupational Justice Framework","2026-03-09",{"date":227,"type":41},"2026-03-11",{"date":229,"type":21},"2026-03-05",{"date":69,"type":21},{"name":47,"class":48},{"id":233,"slug":234,"hasResults":12,"nctId":235,"briefTitle":236,"officialTitle":237,"acronym":4,"eligibilityCriteria":238,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":239,"targetDuration":4,"studyType":22,"phases":241,"briefSummary":242,"conditions":243,"keywords":246,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":225,"lastUpdatePostDateStruct":250,"startDateStruct":251,"completionDateStruct":253,"leadSponsor":255,"locationsCount":49},"100582949","evaluation-of-postoperative-pain-control-in-ear-surgery-100582949","NCT06869967","Evaluation of Postoperative Pain Control in Ear Surgery","Evaluation of Ultrasound-Guided Auricularis Magnus Nerve Block for Postoperative Pain Control in Ear Surgery","Inclusion Criteria:\n\n* Patients undergoing CWD and Mastodectom\n* Patients undergoing elective surgery\n* ASA (American Society of Anesthesiologists) physical status classification I-II\n* Patients over 18 years of age\n\nExclusion Criteria:\n\n* Anticoagulant use\n* Allergy to the drugs to be used\n* ASA (American Society of Anesthesiologists) physical status classification IV-V\n* Presence of infection in the area where the block will be applied\n* Patient's refusal to accept the block application or inability to cooperate with the patient",{"count":240,"type":21},56,[24],"Middle ear surgery is the most popular procedure in ear, nose and throat surgery. Increased sympathetic stimulation after surgery can activate the sympathetic system, causing hypertension and increased heart rate. As a result of these clinical conditions, hemorrhage can occur, which can impair the quality of the surgical field, which is undesirable in middle ear surgery.Clinical studies should be conducted with auricularis magnus nerve block applied in the perioperative period in middle ear surgery and postoperative pain scores.",[244,245],"Post Operative Pain","Analgesia",[247,248,249],"Regional Anesthesia","Ear Surgery","Auricularis Magnus Nerve Block",{"date":227,"type":41},{"date":252,"type":41},"2025-10-20",{"date":254,"type":21},"2026-07-15",{"name":47,"class":48},{"id":257,"slug":258,"hasResults":12,"nctId":259,"briefTitle":260,"officialTitle":261,"acronym":4,"eligibilityCriteria":262,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":211,"enrollmentInfo":263,"targetDuration":4,"studyType":22,"phases":265,"briefSummary":266,"conditions":267,"keywords":4,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":43,"lastUpdatePostDateStruct":270,"startDateStruct":272,"completionDateStruct":274,"leadSponsor":276,"locationsCount":49},"100572793","the-effect-of-preoperative-stoma-simulation-on-anxiety-and-postoperative-adaptation-100572793","NCT06737887","The Effect of Preoperative Stoma Simulation on Anxiety and Postoperative Adaptation","The Effect of Preoperative Stoma Simulation on Anxiety and Postoperative Adaptation: A Randomised Controlled Trial","Inclusion Criteria:\n\n* All patients who are planned for elective stoma surgery,\n* Are between the ages of 18-65,\n* Can speak Turkish,\n* Can read and write,\n* Are conscious,\n* Are willing to participate in the study will be included.\n\nExclusion Criteria:\n\n* Patients with speech or hearing impairments,\n* Those who have had urostomy surgery,\n* Those who have a psychological diagnosis or are taking medication,\n* Those who need intensive care after surgery,\n* Those whose stoma was closed during the study,\n* Those who have complications in the peristomal area,\n* Patients who have had stoma surgery before will be excluded from the study.",{"count":264,"type":21},58,[24],"The majority of patients (60-70%) develop high levels of anxiety before surgery. Surgical patients may experience feelings of anxiety due to insufficient information and counseling before surgery and potential changes in the body caused by surgery. Fears include (but are not limited to) not waking up from anesthesia, not being able to return to previous work and family life, and adaptation concerns regarding new processes after surgery. Patients with fear of complications experience preoperative anxiety four times more than other patients. Other factors affecting preoperative anxiety were determined to be waiting for a long time before surgery, not knowing what will happen during surgery, losing control of the body, not receiving sufficient social support, being exposed to medical errors, and encountering undesirable health outcomes after surgery. The changes that will occur in the body and lifestyle after stoma surgery scare patients and cause them to feel anxiety in the pre-operative period. Despite significant developments in stoma care products and the increase in the number of nurses specialized in stoma care in recent years, the majority of patients experience problems with compliance. For this reason, the compliance of stoma patients with stoma life is increasingly the subject of clinical trials and epidemiological studies. In our country, studies conducted to determine the problems experienced by stoma individuals regarding compliance with stoma and social life are limited. Nursing interventions are recommended to reduce patients' anxiety and increase their compliance with stoma after surgery. This study aims to evaluate the effect of stoma simulation performed preoperative surgery on the patient's anxiety level and postoperative stoma compliance.",[268,269],"Colostomy - Stoma","Ileostomy - Stoma",{"date":271,"type":41},"2026-02-11",{"date":273,"type":21},"2027-01-02",{"date":275,"type":21},"2028-01-02",{"name":47,"class":48},{"id":278,"slug":279,"hasResults":12,"nctId":280,"briefTitle":281,"officialTitle":282,"acronym":283,"eligibilityCriteria":284,"healthyVolunteers":12,"sex":17,"minAge":285,"maxAge":18,"enrollmentInfo":286,"targetDuration":4,"studyType":161,"phases":4,"briefSummary":287,"conditions":288,"keywords":292,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":309,"lastUpdatePostDateStruct":310,"startDateStruct":312,"completionDateStruct":314,"leadSponsor":316,"locationsCount":49},"100602032","ultrasonographic-assessment-of-muscle-morphology-function-and-clinical-findings-in-spastic-cerebral-palsy-100602032","NCT07118228","Ultrasonographic Assessment of Muscle Morphology, Function, and Clinical Findings in Spastic Cerebral Palsy","Evaluation of the Relationship Between Ultrasonographic Muscle Morphology, Functional Properties, and Clinical Parameters in Children With Spastic Cerebral Palsy","US-sCP","Inclusion Criteria:\n\n* Diagnosis of spastic cerebral palsy (SCP) according to the criteria defined by Rosenbaum et al. (2007)\n* Age between 4 and 18 years\n* Gross Motor Function Classification System (GMFCS) Level I, II, or III\n* Manual Ability Classification System (MACS) Level I, II, III, or IV\n\nExclusion Criteria:\n\n* Non-spastic types of cerebral palsy (e.g., dyskinetic, ataxic)\n* Diagnosis of neuromuscular disorders other than cerebral palsy (e.g., hereditary neuropathy, myopathy)\n* Presence of muscle contractures or fixed deformities in the limbs selected for ultrasound and clinical assessment\n* Cognitive or behavioral impairments that prevent cooperation during ultrasound or clinical evaluation\n* Botulinum toxin-A (BoNT-A) injection applied to the target muscles within the last 6 months\n* Current treatment with oral or intrathecal antispastic medications\n* History of orthopedic surgery or selective dorsal rhizotomy involving the target muscles\n* Acute infection, febrile illness, or severe systemic disease (e.g., advanced heart failure, respiratory insufficiency) that may compromise the safety of assessments","4 Years",{"count":133,"type":21},"This study focuses on children with spastic cerebral palsy and aims to examine how muscle morphology and tissue characteristics, as assessed by ultrasound, may relate to functional motor abilities. It is designed as a prospective, cross-sectional, observational study. Planned ultrasound-based assessments include parameters such as muscle thickness, pennation angle, fascicle length, echo intensity, tissue stiffness (via shear wave elastography), and microvascular flow (via superb microvascular imaging). These measurements are intended to be compared with standard clinical evaluations, including the GMFCS, GMFM-66, MAS, MACS, and Tardieu Scale. The study seeks to contribute to a better understanding of the relationship between muscle architecture and functional outcomes, with the goal of generating insights that may inform individualized rehabilitation planning.",[289,290,291],"Muscle Spasticity","Gait Disorders, Neurologic","Cerebral Palsy, Spastic",[293,294,295,296,297,298,299,300,301,302,303,304,305,306,307,308],"Spastic Cerebral Palsy","Muscle Morphology","Shear Wave Elastography","Muscle Architecture","Superb Microvascular Imaging","Muscle Stiffness","Pennation Angle","Fascicle Length","Intramuscular Vascularity","Echo Intensity","GMFM-66","Gross Motor Function","Muscle Morphology and Function","Ultrasound Imaging","Ultrasound Imaging of Spastic Muscle","Functional Assessment","2026-01-30",{"date":311,"type":41},"2026-02-03",{"date":313,"type":41},"2025-12-15",{"date":315,"type":21},"2026-06-30",{"name":47,"class":48},{"id":318,"slug":319,"hasResults":12,"nctId":320,"briefTitle":321,"officialTitle":322,"acronym":4,"eligibilityCriteria":323,"healthyVolunteers":12,"sex":157,"minAge":324,"maxAge":325,"enrollmentInfo":326,"targetDuration":4,"studyType":22,"phases":328,"briefSummary":329,"conditions":330,"keywords":332,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":335,"lastUpdatePostDateStruct":336,"startDateStruct":338,"completionDateStruct":339,"leadSponsor":341,"locationsCount":49},"100616523","laparoscopic-pectopexy-with-and-without-mesh-use-for-pelvic-organ-prolapse-100616523","NCT07306715","Laparoscopic Pectopexy With and Without Mesh Use for Pelvic Organ Prolapse.","Comparison of Pectopexy Operations With and Without Mesh Use After Laparoscopic Hysterectomy for Pelvic Organ Prolapse.","Inclusion Criteria:\n\n* Female patients older than 40 years and younger than 80 years old with symptomatic uterine prolapse\n* Patients who provided written consent for the surgical procedure\n* Patients who do not wish to preserve their uterus\n\nExclusion Criteria:\n\n* Patients who cannot obtain anesthesia approval for laparoscopic surgery\n* Patients who have a confirmed or suspected pregnancy\n* Patients who have abnormal uterine\u002Fcervical\u002Fvaginal bleeding\n* Patients with biopsy-confirmed endometrial hyperplasia or cervical dysplasia\n* Patients with pathology-confirmed genital cancer\n* Patients undergone chemotherapy or radiotherapy for any type of cancer","40 Years","80 Years",{"count":327,"type":21},60,[24],"Genital apical prolapse refers to the descent of the vaginal apex, uterus, or cervix, and surgical treatment is required for adequate apical support. Laparoscopic pectopexy is a surgical method developed as an alternative to the gold standard, sacrocolpopexy, in the treatment of genital organ prolapse, especially for obese patients for whom dissection is difficult. The vaginal cuff is attached to the pectineal ligament with polypropylene mesh in the standard technique. The use of mesh is subject to serious restrictions due to complications such as mesh erosion. Surgical methods without using a mesh may be safer treatment options for patients with genital prolapse. This study aimed to compare the results of Laparoscopic Pectopexy surgery with and without the use of mesh material after hysterectomy.",[331],"Genital Prolapse",[333,334],"pectopexy","mesh","2026-01-29",{"date":337,"type":41},"2026-02-02",{"date":335,"type":41},{"date":340,"type":21},"2027-06-01",{"name":47,"class":48},{"id":343,"slug":344,"hasResults":12,"nctId":345,"briefTitle":346,"officialTitle":347,"acronym":4,"eligibilityCriteria":348,"healthyVolunteers":12,"sex":17,"minAge":349,"maxAge":350,"enrollmentInfo":351,"targetDuration":4,"studyType":22,"phases":353,"briefSummary":354,"conditions":355,"keywords":357,"overallStatus":115,"whyStopped":4,"lastUpdateSubmitDate":362,"lastUpdatePostDateStruct":363,"startDateStruct":365,"completionDateStruct":367,"leadSponsor":369,"locationsCount":49},"100612665","blood-bupivacaine-concentration-after-regional-block-applications-in-pediatric-patients-100612665","NCT07256535","Blood Bupivacaine Concentration After Regional Block Applications in Pediatric Patients","Blood Bupivacaine Concentration After Transversus Abdominis Plane Block and Quadratus Lumborum Block in Pediatric Patients: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Patients undergoing elective inguinal hernia surgery.\n* 1-6 years of age\n* ASA I-II patients\n\nExclusion Criteria:\n\n* Vulnerable populations such as those incapacitated, those in intensive care, those unconscious, those unable to give personal consent, or impressionable individuals will not be included in the study.\n* Although pediatric patients who may be considered a vulnerable population will be included in the study, patients with serious illnesses such as ASA III-IV will not be included in this group.\n* Patients who refuse to participate in the observational study, their parents\u002Flegal guardians,\n* Patients with incomplete data\n* Patients who underwent surgery with an incision other than the planned one for any reason.","1 Year","6 Years",{"count":352,"type":21},20,[24],"Analgesia methods such as systemic analgesics, quadratus lumborum block, and transversus abdominis plane block are used for pain management after lower abdominal surgery. Quadratus lumborum block (QLB) requires the patient to be in the lateral decubitus position, and the drug injection point is deeper. Transversus abdominis plane (TAP) block, on the other hand, can be performed with the patient supine, and the drug injection point is more superficial. However, while TAP block has no effect on visceral pain, QLB is also effective in visceral pain. Furthermore, although the injection point for QLB is deep, systemic absorption of the drug is expected to be lower than with TAP block due to its distance from vascular structures. Consequently, blood local anesthetic concentrations and the risk of local anesthetic systemic toxicity (LAST) are also expected to be lower. Despite the deeper injection, it is expected to provide better analgesia and a lower risk of LAST, making it superior to TAP block. This study aimed to compare the postoperative pain relief effect of quadratus lumborum block and transversus abdominis plane block, routinely performed in the clinic to prevent postoperative pain in pediatric patients undergoing inguinal hernia surgery, using the FLACC (Face, Leg Mobility, Activity, Crying, and Consolability) score for blood bupivacaine dose after drug injection. Based on these data, if lower blood drug concentrations are detected in patients undergoing QLB, the investigators aim to implement this technique routinely in clinical practice.",[356],"Blood Bupivacaine Concentration",[358,359,360,361],"Pediatric Population","Transversus Abdominis Plan Block","Quadratus Lumborum Block","Bupivacaine","2025-12-09",{"date":364,"type":41},"2025-12-17",{"date":366,"type":21},"2026-01-25",{"date":368,"type":21},"2026-06-25",{"name":47,"class":48},{"id":371,"slug":372,"hasResults":12,"nctId":373,"briefTitle":374,"officialTitle":375,"acronym":4,"eligibilityCriteria":376,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":377,"targetDuration":4,"studyType":22,"phases":379,"briefSummary":380,"conditions":381,"keywords":384,"overallStatus":115,"whyStopped":4,"lastUpdateSubmitDate":388,"lastUpdatePostDateStruct":389,"startDateStruct":391,"completionDateStruct":393,"leadSponsor":395,"locationsCount":49},"100613029","music-therapys-effect-on-cancer-patients-undergoing-radiotherapy-100613029","NCT07261267","Music Therapy's Effect on Cancer Patients Undergoing Radiotherapy","The Effect of Music Therapy on the Radiotherapy Experience of Cancer Patients Undergoing Radiotherapy: A Randomised Controlled Trial","Inclusion Criteria:\n\n* Must be a cancer patient 18 years of age or older.\n* Must be newly starting curative external radiotherapy.\n* Must volunteer to participate in the study and sign the Informed Consent form.\n\nExclusion Criteria:\n\n* Having an advanced stage psychiatric disorder (e.g., schizophrenia).\n* Having hearing loss.\n* Having a prior history of an adverse reaction to music therapy.\n* Receiving radiotherapy for palliative (symptom relief) purposes.\n* Having received radiotherapy previously (for reasons such as brachytherapy, a different type of cancer, or recurrence).",{"count":378,"type":21},72,[24],"The goal of this randomized controlled clinical study is to learn about the effects of music therapy on anxiety, stress, pain, and patient satisfaction in cancer patients who are newly starting radiotherapy (radiation treatment).\n\nThe main questions it aims to answer are:\n\nCan music therapy lower the levels of anxiety and stress in patients receiving radiotherapy? Can music therapy improve the pain felt during the radiotherapy experience and overall satisfaction? Researchers will compare patients receiving standard radiotherapy (control group) with patients receiving music therapy alongside their radiotherapy (experimental group).\n\nParticipants (72 total) will:\n\nBe 18 years and older and newly starting curative radiotherapy. Answer short surveys (STAI-SF, SDT, VAS) to measure their anxiety, stress, and pain levels before and after treatment.\n\nParticipants in the experimental group will receive a 15-20 minute music therapy session consisting of meditative and instrumental music during their first radiotherapy session.\n\nThis study aims to provide reliable data to guide clinical practice by showing whether music therapy offers a multifaceted approach to managing the psychological and physical challenges associated with cancer treatment.",[382,383],"Cancer","Radiotherapy",[385,383,386,28,387],"Music Therapy","Anxiety","Stress","2025-11-21",{"date":390,"type":41},"2025-12-03",{"date":392,"type":21},"2025-12-01",{"date":394,"type":21},"2026-01-31",{"name":47,"class":48},{"id":397,"slug":398,"hasResults":12,"nctId":399,"briefTitle":400,"officialTitle":400,"acronym":4,"eligibilityCriteria":401,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":211,"enrollmentInfo":402,"targetDuration":4,"studyType":22,"phases":404,"briefSummary":405,"conditions":406,"keywords":4,"overallStatus":115,"whyStopped":4,"lastUpdateSubmitDate":408,"lastUpdatePostDateStruct":409,"startDateStruct":411,"completionDateStruct":412,"leadSponsor":414,"locationsCount":4},"100608452","the-effectiveness-of-leap-motion-based-virtual-reality-in-the-rehabilitation-of-flexor-tendon-injuries-of-the-hand-100608452","NCT07201740","The Effectiveness of Leap Motion-Based Virtual Reality in the Rehabilitation of Flexor Tendon Injuries of the Hand","Inclusion Criteria:\n\nAge between 18 and 65 years\n\nFlexor tendon injury of the hand (zones II-V)\n\nEarly surgical repair completed\n\nAt least 5 weeks postoperative\n\nEligible for routine hand rehabilitation program\n\nExclusion Criteria:\n\nCommunication problems\n\nCognitive impairment\n\nAdditional musculoskeletal, neurological, or rheumatological diseases affecting upper extremity function\n\nMultiple trauma cases",{"count":403,"type":21},66,[24],"This randomized controlled clinical trial aims to evaluate the effectiveness of a Leap Motion-based virtual reality rehabilitation program in patients who underwent surgical repair for flexor tendon injuries of the hand (zones II-V). A total of 66 participants, aged 18-65 years and at least 5 weeks postoperative, will be randomly assigned to two groups: the intervention group will receive routine hand rehabilitation plus Leap Motion-based virtual reality therapy for 20 minutes per day, 5 days per week, for 4 weeks; while the control group will continue routine hand rehabilitation only. Outcomes will include joint range of motion measured with a goniometer, pain intensity assessed with a Visual Analog Scale (VAS), grip strength measured with a Jamar dynamometer, and functional outcomes assessed using the QuickDASH questionnaire. The primary endpoint is the change in range of motion, grip strength, and QuickDASH score from baseline to post-treatment. Secondary endpoints include changes in upper extremity function and pain tolerance. All interventions will be delivered under therapist supervision. This study is expected to provide evidence on whether integrating Leap Motion-based virtual reality into conventional rehabilitation improves clinical outcomes after flexor tendon repair.",[407],"Flexor Tendon Injuries of the Hand (Zones II-V)","2025-09-30",{"date":410,"type":41},"2025-10-01",{"date":410,"type":21},{"date":413,"type":21},"2026-02-01",{"name":47,"class":48},{"id":416,"slug":417,"hasResults":12,"nctId":418,"briefTitle":419,"officialTitle":420,"acronym":4,"eligibilityCriteria":421,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":131,"enrollmentInfo":422,"targetDuration":4,"studyType":22,"phases":423,"briefSummary":424,"conditions":425,"keywords":4,"overallStatus":115,"whyStopped":4,"lastUpdateSubmitDate":427,"lastUpdatePostDateStruct":428,"startDateStruct":430,"completionDateStruct":431,"leadSponsor":433,"locationsCount":4},"100606159","genicular-vs-ipack-block-for-analgesia-in-knee-arthroplasty-100606159","NCT07171931","Genicular vs IPACK Block for Analgesia in Knee Arthroplasty","Comparison of the Postoperative Analgesic Efficacy of Genicular Block and IPACK Block in Addition to Adductor Canal Block in Knee Arthroplasty","Inclusion Criteria:\n\n* Patients undergoing unilateral total knee arthroplasty\n* ASA physical status I-III\n\nExclusion Criteria:\n\n* BMI \\> 35\n* Patients \\\u003C 50 kg\n* Allergy to study medications",{"count":378,"type":21},[24],"Total knee arthroplasty (TKA) is one of the most frequently performed orthopedic procedures, and with the aging population, the global number of TKA cases is expected to increase sixfold within the next decade. Postoperative pain following TKA is often severe and difficult to manage, which may increase the risk of developing chronic pain. Effective pain control is therefore a major concern, and multimodal analgesia is recommended to enhance analgesia, reduce opioid consumption, and minimize opioid-related side effects.\n\nPeripheral nerve blocks (PNBs) are an integral part of multimodal regimens. Among them, the adductor canal block (ACB), which provides analgesia to the anteromedial aspect of the knee while preserving motor function, is widely used. The optimal analgesic strategy for TKA should not only ensure adequate pain relief but also maintain quadriceps strength to allow early mobilization. Motor-sparing blocks combined with multimodal analgesia have become increasingly popular because they facilitate early rehabilitation, decrease opioid requirements, and improve recovery outcomes.\n\nThe knee joint has a complex innervation, receiving contributions from the femoral, sciatic, and obturator nerves. For this reason, combining different PNBs may provide superior analgesia compared to a single block (2). The genicular nerves, consisting of branches from the femoral, common peroneal, saphenous, tibial, and obturator nerves, innervate the knee capsule. Genicular nerve block specifically targets these branches and has been used to manage postoperative pain in TKA patients.\n\nAnother motor-sparing option is the interspace between the popliteal artery and posterior capsule of the knee (IPACK) block, which provides analgesia to the posterior aspect of the knee. Using ultrasound guidance, local anesthetic is deposited between the posterior capsule and the popliteal artery. This approach spares the main trunks of the tibial and common peroneal nerves while effectively blocking the terminal branches innervating the posterior capsule, including the genicular nerves and the popliteal plexus.\n\nHowever, there are no studies in the literature directly comparing IPACK and genicular blocks. With this study, the investigators aim to compare the efficacy of these two blocks in patients undergoing TKA.",[426],"Postoperative Pain Management in Total Knee Arthroplasty","2025-09-10",{"date":429,"type":41},"2025-09-15",{"date":429,"type":21},{"date":432,"type":21},"2026-04-01",{"name":47,"class":48},{"id":435,"slug":436,"hasResults":12,"nctId":437,"briefTitle":438,"officialTitle":439,"acronym":4,"eligibilityCriteria":440,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":211,"enrollmentInfo":441,"targetDuration":4,"studyType":22,"phases":442,"briefSummary":443,"conditions":444,"keywords":4,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":447,"lastUpdatePostDateStruct":448,"startDateStruct":450,"completionDateStruct":452,"leadSponsor":453,"locationsCount":49},"100555069","paravertebral-block-and-erector-spinae-plane-block-on-intraoperative-opioid-consumption-using-nol-index-100555069","NCT06507293","Paravertebral Block and Erector Spinae Plane Block on Intraoperative Opioid Consumption Using NoL Index","Comparison of the Effects of Paravertebral Block and Erector Spinae Plane Block on Intraoperative Opioid Consumption Using NoL Index in Thoracotomy","Inclusion Criteria:\n\n* Patients undergo elective thoracotomy surgery\n* ASA physical status I-III\n\nExclusion Criteria:\n\n* Spinal deformities\n* BMI\\>35\n* Patiens \\\u003C50 kg\n* Allergies to study medications",{"count":327,"type":21},[24],"Thoracotomy is among the most painful surgical procedures and can cause severe pain with a high incidence. Inadequate treatment of acute postoperative pain may lead to undesired complications. Paravertebral block (PVB) is an effective technique that provides adequate analgesia in thoracic surgeries. However, it is an advanced technique with potential complication risks. Erector spinae plane block (ESPB) is a relatively new and considered as a safer technique that provides comparable analgesia. However, the results are controversial and there are few studies that compares the effect of these blocks in thoracic surgeries. As well as the undesired effects of inadequate pain management, high doses of perioperative opioid usage may contribute to the development of dose-dependent long-term adverse events. Hemodynamic parameters are generally used to determine the intraoperative need for opioids in patients; however, hemodynamic parameters are not standardized and they do not provide a clear assessment. The Nociception Level (NoL) index is generated from five different parameters (heart rate, heart Rrate variability, photo-plethysmographic waveform amplitude, skin conductance level, number of skin conductance fluctuations, and their time derivatives) using a finger probe and is a promising monitoring technique. Selecting an effective analgesia method and determining the appropriate dose of opioids using NoL monitoring can reduce perioperative and postoperative complications and shorten hospital stays, allowing patients to return to daily life sooner. Additionally, preventing chronic pain syndromes that may develop in patients with inadequate analgesia, personalizing each patient's analgesia level, reducing healthcare costs, and improving quality of life can be achieved. The data from this study can demonstrate the analgesic efficacy of simpler regional anesthesia techniques, contributing to the widespread adoption of regional anesthesia applications, which is a crucial step in multimodal analgesia, thereby ensuring more effective pain management for surgical patients.",[445,446],"Postoperative Pain","Opioid Use","2025-08-27",{"date":449,"type":41},"2025-09-04",{"date":451,"type":41},"2024-08-01",{"date":392,"type":21},{"name":47,"class":48},{"id":455,"slug":456,"hasResults":12,"nctId":457,"briefTitle":458,"officialTitle":459,"acronym":4,"eligibilityCriteria":460,"healthyVolunteers":12,"sex":17,"minAge":461,"maxAge":462,"enrollmentInfo":463,"targetDuration":4,"studyType":161,"phases":4,"briefSummary":465,"conditions":466,"keywords":468,"overallStatus":115,"whyStopped":4,"lastUpdateSubmitDate":470,"lastUpdatePostDateStruct":471,"startDateStruct":473,"completionDateStruct":475,"leadSponsor":477,"locationsCount":49},"100602199","postoperative-chronic-pain-in-children-aged-8-to-17-100602199","NCT07120399","Postoperative Chronic Pain in Children Aged 8 to 17","Investigation of the Incidence of Postoperative Chronic Pain in Children Aged 8 to 17 Years","Inclusion Criteria:\n\n* Voluntary participation\n* Undergoing a surgical procedure under anesthesia at our hospital\n* Availability of complete patient data for a 6-month postoperative follow-up period\n\nExclusion Criteria:\n\n* Presence of speech or communication disorders\n* Development of postoperative complications\n* Undergoing any additional surgical procedure for any reason during the 6 months follow-up period\n* Having diagnosed psychiatric or neurological disorders\n* Having a pre-existing history of chronic or long-term pain","8 Years","17 Years",{"count":464,"type":21},323,"The objective of this study is to assess the incidence of chronic postoperative pain in pediatric patients aged 8 to 17 years following surgical procedures. Furthermore, it seeks to identify potential risk factors contributing to the development of such pain and to evaluate its long-term implications.",[467],"Postoperative Chronic Pain",[28,467,469],"Quality of Life","2025-08-12",{"date":472,"type":41},"2025-08-14",{"date":474,"type":21},"2025-08-15",{"date":476,"type":21},"2026-08-15",{"name":47,"class":48},{"id":479,"slug":480,"hasResults":12,"nctId":481,"briefTitle":482,"officialTitle":483,"acronym":4,"eligibilityCriteria":484,"healthyVolunteers":56,"sex":17,"minAge":18,"maxAge":131,"enrollmentInfo":485,"targetDuration":4,"studyType":161,"phases":4,"briefSummary":487,"conditions":488,"keywords":490,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":494,"lastUpdatePostDateStruct":495,"startDateStruct":497,"completionDateStruct":499,"leadSponsor":501,"locationsCount":49},"100596333","lung-protective-ventilation-and-driving-pressure-guided-peep-titration-in-cabg-surgery-100596333","NCT07044089","Lung Protective Ventilation and Driving Pressure Guided PEEP Titration in CABG Surgery","Comparison of Individualized PEEP Application Versus Fixed PEEP Application for Lung-Protective Ventilation in Patients Undergoing On-Pump Coronary Artery Bypass Grafting Surgery","Inclusion Criteria:\n\n* Patients scheduled for elective on-pump coronary artery bypass graft surgery via median sternotomy\n* Patients between the ages of 18 and 70\n* ASA (American Society of Anesthesiologists) physical status classification II-III\n\nExclusion Criteria:\n\n* Patients with an ejection fraction below 35%\n* Patients who did not consent to participate in the study\n* Patients undergoing emergency surgery\n* Patients who are allergic to the anesthetic drugs used\n* Patients who have undergone lung resection\n* Those with a history of mechanical ventilation in the 2 months before surgery\n* Patients who have undergone total circulatory arrest and deep hypothermia\n* Patients with obstructive sleep apnea syndrome requiring long-term ventilation assistance\n* Morbid obesity (Body Mass Index\\>35kg\u002Fm2)\n* Patients with refractory hypoxemia (arterial oxygen saturation below 88% despite 100% oxygen inhalation)\n* COPD (FEV1\\\u003C70%)\n* Patients with chronic renal failure (serum creatine\\>1.8 mg\u002Fdl)\n* Anemia (Hg\\\u003C10 gr\u002Fdl)\n* Patients who have had an intraaortic balloon pump placed.",{"count":486,"type":21},86,"Our aim in this study is to compare fixed and individualized PEEP (driving pressure guided ) application for intraoperative lung protective ventilation in patients undergoing on-pump CABG surgery.\n\nResearcher aimed to compare the effects of two different PEEP application methods on intraoperative hemodynamics, respiratory mechanics, and gas exchange, as well as postoperative extubation times, respiratory complications (atelectasis, need for non invasive mechanical ventilatıon, need for re-entubatıon) length of stay in the intensive care unit, and discharge times.",[489],"Peep Titration in Lung Protective Ventilation",[491,492,493],"Lung Protective Ventilation","Fixed PEEP","Individualized PEEP","2025-08-06",{"date":496,"type":41},"2025-08-08",{"date":498,"type":41},"2025-07-23",{"date":500,"type":21},"2027-09-01",{"name":47,"class":48},{"id":503,"slug":504,"hasResults":12,"nctId":505,"briefTitle":506,"officialTitle":507,"acronym":4,"eligibilityCriteria":508,"healthyVolunteers":56,"sex":17,"minAge":18,"maxAge":509,"enrollmentInfo":510,"targetDuration":4,"studyType":22,"phases":512,"briefSummary":513,"conditions":514,"keywords":519,"overallStatus":115,"whyStopped":4,"lastUpdateSubmitDate":522,"lastUpdatePostDateStruct":523,"startDateStruct":525,"completionDateStruct":527,"leadSponsor":529,"locationsCount":4},"100596656","omaha-system-based-health-application-on-improving-knowledge-attitude-and-behaviors-regarding-infectious-disease-prevention-in-the-community-100596656","NCT07048301","Omaha System-Based Health Application on Improving Knowledge, Attitude, and Behaviors Regarding Infectious Disease Prevention in the Community","Developing an Omaha System-Based Health Application on Improving Knowledge, Attitude, and Behaviors Regarding Infectious Disease Prevention in the Community","Inclusion criteria:\n\n* being aged between 18 and 64 years,\n* living in two container cities,\n* having a knowledge score of 'very low (1)' and 'low (2)' on the Omaha System Problem Rating Scale for Outcome for Communicable\u002F Infectious Problem Knowledge Parameter,\n* being literate,\n* owning a smartphone.\n\nExclusion criteria:\n\n* having impaired vision or hearing,\n* having a mental illness,\n* not owning a smartphone,\n* being pregnant or postpartum,\n* being participants in another scientific study,\n* refusing to participate.","64 Years",{"count":511,"type":21},112,[24],"Background: Infectious diseases remain significant public health concerns due to several factors such as climate and environmental changes and natural disasters. Mobile health applications (mHealth apps) can be an appropriate way for fostering community participation, disseminating knowledge, and promoting behavior change toward infectious disease prevention. This study aims to describe a protocol for a pilot randomized controlled study to evaluate the impact of the Omaha System-Based mHealth app (BUHOS) on improving knowledge, attitude, and behaviors (KAB) regarding infectious disease prevention in an earthquake-affected region of Türkiye.\n\nMethods: This study is a two-armed, parallel-group, randomized controlled trial design. A total of 112 eligible participants will be recruited from two separate container cities of an earthquake-affected region. These participants will be randomly allocated to either an intervention group or a control group. BUHOS will be designed based on the Omaha System, a widely recognized standardized taxonomy for the assessment, planning, and evaluation of healthcare services. BUHOS will be a two-week nursing intervention that includes monitoring KAB, employing Education, Guidance and Counseling (education videos), and Surveillance (reminder messages), and assessing the outcomes. Outcome variables will include the Problem Rating Scale for Outcomes, Community Communicable Diseases Knowledge Survey, Communicable Diseases Risk Awareness and Protection Scale and System Usability Scale. Outcome variables will be assessed on the 15th and 30th day after intervention.\n\nHypotheses:\n\nH1: Among the Omaha System Problems, the Communicable\u002F Infectious Condition Problem Knowledge score will be higher on the 15th and 30th days compared to the control group.\n\nH2: Infectious diseases risk awareness and prevention score will be higher on the 15th and 30th days compared to the control group.\n\nH3: Communicable\u002F Infectious Condition Status Behaviour Parameter score will be higher on the 15th and 30th days compared to the control group H4: The knowledge and behaviour of the communicable\u002F infectious status and the awareness and prevention of the risk of infectious diseases of the experimental group will be higher than before the intervention on the 15th and 30th days.",[515,516,517,518],"Infectious Diseases","Attitude","Behavior","Knowledge",[520,521],"Omaha System","Mobile health app","2025-06-24",{"date":524,"type":41},"2025-07-02",{"date":526,"type":21},"2025-09",{"date":528,"type":21},"2026-06",{"name":47,"class":48},{"id":531,"slug":532,"hasResults":12,"nctId":533,"briefTitle":534,"officialTitle":534,"acronym":4,"eligibilityCriteria":535,"healthyVolunteers":12,"sex":157,"minAge":536,"maxAge":537,"enrollmentInfo":538,"targetDuration":4,"studyType":22,"phases":540,"briefSummary":541,"conditions":542,"keywords":544,"overallStatus":115,"whyStopped":4,"lastUpdateSubmitDate":548,"lastUpdatePostDateStruct":549,"startDateStruct":551,"completionDateStruct":553,"leadSponsor":555,"locationsCount":4},"100590040","effect-of-maintenance-of-intraoperative-normothermia-in-cesarean-section-on-thermal-comfort-serum-cortisol-and-apgar-score-a-randomized-controlled-trial-100590040","NCT06962241","Effect of Maintenance of Intraoperative Normothermia in Cesarean Section on Thermal Comfort, Serum Cortisol and Apgar Score: A Randomized Controlled Trial","Inclusion Criteria:• Being 19 years of age or older pregnant\n\n* Being at least a primary school graduate\n* Having an elective cesarean section with spinal\u002Fepidural anesthesia\n* Being at or above the 38th week of pregnancy\n* Being in the ASA I (Normal, healthy person with no disease or systemic problem other than surgical pathology that does not cause a systemic disorder) class\n* Not being diagnosed with high-risk pregnancy (such as oligodydroamnios, premature membrane rupture, gestational diabetes mellitus, preeclampsia, fetal tachycardia, nonreactive NST, intrauterine growth retardation)\n* Having a body mass index of \\>19 kg\u002Fm2 and \\\u003C40 kg\u002Fm2\n* Having a singleton pregnancy\n* Having a healthy fetus\n* Having a fasting period of 2-6 hours before surgery\n* Being normothermic (36-37.5°C) (tympanic measurement) before surgery\n\nExclusion Criteria: •Having comorbidities that require emergency delivery or accompany it (severe preeclampsia, bleeding placenta previa, abruption placenta, cord prolapse, fetal distress)\n\n* Need for intensive care in the mother or newborn after cesarean section\n* Being anemic with a hemoglobin value below 10 g\u002Fdl according to the World Health Organization (2001)\n* Not having platelet values within the reference values\n* Having any disease that will disrupt the bleeding clotting mechanism (hemophilia, liver failure, vitamin K deficiency, etc.)\n* Having a body core temperature above 37.5°C and below 36°C on the morning of surgery\n* Having malnutrition, thyroid function and other endocrine disorders, Parkinson's, peripheral circulatory disorders, Diabetes Mellitus, heart disease and a history of stroke\n* Having any deterioration on the skin surface of the arms and legs (ecchymosis, edema, urticaria, etc.)","19 Years","39 Years",{"count":539,"type":21},50,[24],"Cesarean section is a common method of delivery worldwide today. According to WHO, cesarean section accounts for more than 1 in 5 (21%) of all births, and it is predicted that approximately one-third (29%) of births will be by cesarean section by 2030. Although cesarean section is a vital and life-saving surgery, it can unnecessarily put mothers and babies at risk for short- and long-term health problems when performed without a medical necessity. Unintended perioperative hypothermia, defined as the inadvertent lowering of core temperature below 36°C during surgery, is a well-known complication of anesthesia. Hypothermia can increase the risk of infection by suppressing the immune system, prolonging the recovery process, and triggering postpartum complications. Maintaining maternal body temperature during cesarean section helps reduce postoperative complications, reduce the risk of infection, and accelerate the recovery process. It is also critical for the health of the baby. Keeping the newborn's body temperature stable can help minimize risks such as hypoxia at birth. However, there are increasing studies showing that temperature control is not only limited to maternal health but also has serious effects on the baby after birth. Therefore, it is understood that maintaining body temperature during cesarean section is an important factor in improving the quality of life for both individuals. This article aims to deeply examine the role of temperature control during cesarean section on maternal and fetal health and the benefits of this intervention.",[543],"Pregnancy",[545,546,547],"PREGNANCY","NORMOTERMIA","APGAR SCORE","2025-04-29",{"date":550,"type":41},"2025-05-08",{"date":552,"type":21},"2025-06",{"date":554,"type":21},"2026-07",{"name":47,"class":48},{"id":557,"slug":558,"hasResults":12,"nctId":559,"briefTitle":560,"officialTitle":561,"acronym":4,"eligibilityCriteria":562,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":563,"targetDuration":4,"studyType":22,"phases":565,"briefSummary":566,"conditions":567,"keywords":4,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":569,"lastUpdatePostDateStruct":570,"startDateStruct":572,"completionDateStruct":574,"leadSponsor":576,"locationsCount":49},"100574362","effect-of-artificial-intelligence-assisted-motivational-talk-on-patients-fear-of-movement-and-mobility-level-after-knee-replacement-100574362","NCT06758297","Effect of Artificial Intelligence-Assisted Motivational Talk on Patients' Fear of Movement and Mobility Level After Knee Replacement","Effect of Artificial Intelligence-Assisted Motivational Talk on Patients' Fear of Movement and Mobility Level After Knee Replacement: a Randomized Controlled Trial","Inclusion Criteria:\n\n* The patient must have had knee replacement surgery,\n* Be over 18 years of age,\n* Agree to participate in the study,\n* Be able to understand and speak Turkish,\n* Be able to read and write\n\nExclusion Criteria:\n\n* Cancellation or postponement of patient's surgery\n* Patients in pain,\n* Those whose walking is not recommended by the physician,\n* Those with mental disabilities or psychological disorders,\n* Patients who are alcohol or drug addicts,\n* Those with hearing or visual impairments,\n* Patients who do not want to use the headphones that will be used in the study.",{"count":564,"type":21},76,[24],"Patients may have fears about moving after TKA surgery. This fear has been described in the literature. Fear of re-injury has also been called kinesiophobia, which is the primary psychosocial structure in the fear-avoidance model. Injury or surgery can create feelings of uncertainty and fear of how much the injury will affect future function. This situation causes the individual to have negative attitudes towards activity. For this reason, kinesiophobia is a psychological element that can affect patient outcomes and recovery after knee trauma or knee surgery. Kinesiophobia is considered a normal reaction in the early postoperative period. However, it can affect patients' early mobility after TKA. It is important to improve functional outcomes in the early period, especially in knee surgeries. Patients may delay mobilization because they feel a fear of falling after surgery, and as this delay increases, their mobility is affected worse. The only solution to this situation, which can enter a vicious circle, is to determine patients' fear of falling and apply interventions accordingly. There are studies in the literature evaluating the fear of movement after total knee arthroplasty and its effect on patients' mobility levels. However, no study has been found investigating the effect of a motivational speech prepared with the help of artificial intelligence on patients. The World Health Organization (WHO) has published a four-year global strategy report on digital health within the scope of the vision of health everywhere and for everyone. According to this report, digital health is defined as \"the adoption of digital technologies to improve and develop health\". The use of artificial intelligence technology is increasing day by day in the changing and developing world. It is known that nurses constitute 45% of all health professionals in the field of health and that insufficient staff number continues to be a priority problem. It is expected that insufficient staff will be supported and efficiency will increase with the contribution of artificial intelligence, which is the copy of human intelligence with advanced technology. With this research, we aim to both support staff and improve patient outcomes by using artificial intelligence technologies. The aim of this study is to evaluate the effect of an artificial intelligence-supported motivational speech on patients' fear of movement and mobility level after knee replacement.",[568],"Knee Arthroplasty, Total","2025-03-24",{"date":571,"type":41},"2025-03-25",{"date":573,"type":41},"2024-12-30",{"date":575,"type":21},"2025-06-30",{"name":47,"class":48},{"id":578,"slug":579,"hasResults":12,"nctId":580,"briefTitle":581,"officialTitle":582,"acronym":4,"eligibilityCriteria":583,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":584,"targetDuration":4,"studyType":22,"phases":586,"briefSummary":587,"conditions":588,"keywords":4,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":591,"lastUpdatePostDateStruct":592,"startDateStruct":594,"completionDateStruct":596,"leadSponsor":597,"locationsCount":49},"100574361","effect-of-laughter-yoga-on-surgical-fear-and-anxiety-in-patients-applied-before-ureteroscopy-100574361","NCT06758284","Effect of Laughter Yoga on Surgical Fear and Anxiety in Patients Applied Before Ureteroscopy","Effect of Laughter Yoga on Surgical Fear and Anxiety in Patients Applied Before Ureteroscopy: a Randomized Controlled Trial","Inclusion Criteria:\n\nIt will be applied to patients who agree to participate in the study, are scheduled to undergo ureteroscopy in a urological surgery clinic, have no hearing or vision problems, are over the age of 18, understand and speak Turkish, are literate, and can communicate.\n\nExclusion Criteria:\n\nPatients with mental retardation and any psychiatric disorder, alcohol or drug addiction, hypertension or heart disease, hernia, glaucoma will be excluded.",{"count":585,"type":21},92,[24],"Surgical fear is a situation where a person experiences excessive fear of surgical procedures. This fear can negatively affect the person's normal life and is usually more intense in the pre-operative period. The causes of surgical fear include factors such as previous negative surgical experiences, lack of sufficient information, post-operative pain and complications. In addition, factors such as age, gender, and level of education can also affect fear. This fear can lead to physical and psychological problems along with stress; symptoms such as increased heart rate, dizziness, and muscle tension can be seen. Methods such as cognitive-behavioral therapy, meditation, and hypnosis can be used in the treatment of surgical fear. In addition, anxiety can also arise from thinking about the surgical procedure, post-operative complications, fear of anesthesia, or pain. High-risk surgeries and past negative experiences can increase anxiety. High anxiety before surgery can lead to psychological and physical problems. Nurses should offer anxiety-reducing techniques (breathing exercises, relaxation) by taking into account the needs of patients. In addition, having relatives with the patient can help relieve anxiety. Laughter yoga is considered an effective complementary therapy to reduce surgical fear and anxiety. Developed in India in 1995, this method involves simulating laughter with yoga breathing techniques. Laughter yoga relaxes muscles, increases pain threshold, and improves overall psychological well-being. This study aims to evaluate the effects of laughter yoga on patients undergoing ureteroscopy.",[589,590],"Ureteroscopy","Kidney Stones","2024-12-26",{"date":593,"type":41},"2025-01-03",{"date":595,"type":41},"2024-07-01",{"date":573,"type":21},{"name":47,"class":48},{"id":599,"slug":600,"hasResults":12,"nctId":601,"briefTitle":602,"officialTitle":603,"acronym":4,"eligibilityCriteria":604,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":186,"enrollmentInfo":605,"targetDuration":4,"studyType":22,"phases":607,"briefSummary":608,"conditions":609,"keywords":610,"overallStatus":115,"whyStopped":4,"lastUpdateSubmitDate":614,"lastUpdatePostDateStruct":615,"startDateStruct":617,"completionDateStruct":619,"leadSponsor":621,"locationsCount":49},"100567074","comparison-of-esp-block-and-stap-plane-block-100567074","NCT06663449","Comparison of ESP Block and STAP Plane Block","Comparison of ESP Block and STAP Plane Block in Laparoscopic Cholecystectomy Surgery","Inclusion Criteria:\n\n* Patients who will undergo laparoscopic cholecystectomy:\n* 18-75 years old\n* ASA I-II-III patients\n\nExclusion Criteria:\n\n* Use of anticoagulant drugs\n* Known allergy to drugs to be used\n* Infection in the area where the block will be performed\n* Patient's reluctance",{"count":606,"type":21},68,[24],"In order to effectively manage postoperative analgesia in patients planned to undergo elective laparoscopic cholecystectomy, patients will be divided into 2 (two) groups and informed consent forms will be obtained after the necessary information is provided so that both groups can be included in the study. In the group planned to undergo erector spinae plane block, erector spinae plane block will be performed after monitoring and sedation in the operating room block unit before being taken to the surgical table preoperatively and postoperative PCA analgesia will be applied. In patients who will undergo subcostal transversus abdominis plane block, subcostal tap block will be performed after monitoring and sedation in the operating room block unit before being taken to the surgical table preoperatively and postoperative PCA analgesia will be applied. The patients' perioperative pain will be monitored with NOL (nociception level) monitor. Remifentanil dose will be adjusted to keep the NOL level between 10 and 25. After the patients are followed up for 24 hours postoperatively, their additional analgesia needs and amounts during this process will be compared. In this way, it is aimed to show that the analgesic method can be used effectively in the follow-up of pain management by comparing the Erector Spina Plane block and the Subcostal Transversus Abdominis Plane block as an effective analgesic application in laparoscopic cholecystectomy operations.",[445],[611,612,613],"regional anesthesia","Erector spinae plane block","subcostal transversus abdominis plane block","2024-12-04",{"date":616,"type":41},"2024-12-05",{"date":618,"type":21},"2024-12-15",{"date":620,"type":21},"2025-06-01",{"name":47,"class":48},{"id":623,"slug":624,"hasResults":12,"nctId":625,"briefTitle":626,"officialTitle":627,"acronym":4,"eligibilityCriteria":628,"healthyVolunteers":12,"sex":57,"minAge":18,"maxAge":325,"enrollmentInfo":629,"targetDuration":4,"studyType":22,"phases":631,"briefSummary":632,"conditions":633,"keywords":4,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":638,"lastUpdatePostDateStruct":639,"startDateStruct":641,"completionDateStruct":643,"leadSponsor":645,"locationsCount":73},"100510521","comparison-of-airtraq-in-class-2-3-obese-and-nonobese-men-during-intubation-a-prospective-randomized-clinical-study-100510521","NCT05927519","Comparison of Airtraq in Class 2-3 Obese and Nonobese Men During Intubation: a Prospective Randomized Clinical Study","Airtraq in Obese and Nonobese Men","Inclusion Criteria:\\> 18 age men gender elective operation requring intuabtion -\n\nExclusion Criteria:\\\u003C18 age women emergency operation\n\n\\-",{"count":630,"type":21},80,[24],"Morbid obesity is a growing disease. Intubations of these patients mostly difficult. Video laryngoscopes have to be used during the intubation of these patients. The intubation of men is more complicated and difficult than obese women. There were no trials compared to the new video laryngoscopes in morbidly obese men. Patients will be divided into two groups; non-obese and klas 2-3 obese. Airtraq will be used for their intubation. The time for intubation will be the primary aim of this prospective randomized study. The insertion time, perioperative hemodynamic variables, and postoperative complications will also be recorded.",[634,635,636,637],"Obesity, Morbid","Intubation; Difficult or Failed","Video Laryngoscope","Men","2024-10-24",{"date":640,"type":41},"2024-10-28",{"date":642,"type":41},"2024-10-25",{"date":644,"type":21},"2027-10-05",{"name":47,"class":48},""]