[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Konya Meram State Hospital\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":66},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,41],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":17,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":22,"conditions":23,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":35,"leadSponsor":37,"locationsCount":40},"100638839","effect-of-sarcopenia-and-frailty-on-rocuronium-pharmacodynamics-in-geriatric-patients-100638839",false,"NCT07580144","Effect of Sarcopenia and Frailty on Rocuronium Pharmacodynamics in Geriatric Patients","Inclusion Criteria:\n\n* Scheduled to undergo elective surgery under general anesthesia requiring endotracheal intubation\n* Planned use of rocuronium for neuromuscular blockade\n* Quantitative neuromuscular monitoring planned during anesthesia\n* American Society of Anesthesiologists physical status I-III\n* Ability to provide written informed consent\n* Completion of preoperative frailty and sarcopenia assessment\n\nExclusion Criteria:\n\n* Emergency surgery\n* Known neuromuscular disease\n* History of allergy or contraindication to rocuronium, sugammadex\n* Severe hepatic insufficiency\n* Severe renal insufficiency\n* Use of drugs known to significantly affect neuromuscular transmission\n* Preoperative mechanical ventilation or intensive care unit admission\n* Inability to perform a frailty or sarcopenia assessment\n* Patients in whom quantitative neuromuscular monitoring cannot be properly performed\n* Refusal to participate in the study","ALL","65 Years","80 Years",{"count":19,"type":20},100,"ESTIMATED","OBSERVATIONAL","This prospective observational study aims to evaluate whether sarcopenia and frailty affect the pharmacodynamic profile of rocuronium in geriatric patients undergoing elective surgery under general anesthesia.",[24,25,26,27,28],"Sarcopenia","Frailty","Neuromuscular Blockade","Rocuronium","Pharmacodynamics","RECRUITING","2026-05-13",{"date":32,"type":33},"2026-05-15","ACTUAL",{"date":30,"type":33},{"date":36,"type":20},"2026-08-05",{"name":38,"class":39},"Konya Meram State Hospital","OTHER",1,{"id":42,"slug":43,"hasResults":11,"nctId":44,"briefTitle":45,"officialTitle":46,"acronym":4,"eligibilityCriteria":47,"healthyVolunteers":11,"sex":15,"minAge":48,"maxAge":4,"enrollmentInfo":49,"targetDuration":4,"studyType":51,"phases":52,"briefSummary":54,"conditions":55,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":59,"lastUpdatePostDateStruct":60,"startDateStruct":62,"completionDateStruct":63,"leadSponsor":65,"locationsCount":40},"100628186","front-block-for-quality-of-recovery-after-total-hip-arthroplasty-100628186","NCT07458360","FRONT Block for Quality of Recovery After Total Hip Arthroplasty","Effect of Femoral Rami and Obturator Nerve Trunk (FRONT) Block on Postoperative Quality of Recovery After Total Hip Arthroplasty: A Prospective Randomized Controlled Trial","Inclusion Criteria:\n\n* Age ≥ 18 years\n* Scheduled for total hip arthroplasty under spinal anesthesia\n* American Society of Anesthesiologists (ASA) physical status I-III\n* Ability to understand and complete the QoR-15 questionnaire\n* Provided written informed consent\n\nExclusion Criteria:\n\n* Refusal to participate\n* Contraindication to spinal anesthesia or regional block\n* Allergy to study medications\n* Chronic opioid use (daily use for more than 3 months)\n* Neurological or neuromuscular disorders affecting the lower extremities\n* Infection at the injection site\n* Coagulation disorders\n* Cognitive impairment prevents questionnaire completion","18 Years",{"count":50,"type":20},80,"INTERVENTIONAL",[53],"NA","This prospective randomized controlled trial evaluates the effect of ultrasound-guided unilateral Femoral Rami and Obturator Nerve Trunk (FRONT) block on postoperative quality of recovery in patients undergoing elective total hip arthroplasty.",[56,57,58],"Osteoarthritis of the Hip","Postoperative Pain","Quality of Recovery","2026-04-25",{"date":61,"type":33},"2026-04-28",{"date":59,"type":33},{"date":64,"type":20},"2026-07-05",{"name":38,"class":39},""]