[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Konya Necmettin Erbakan Üniversitesi\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":90},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,39,59],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":22,"studyType":23,"phases":4,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":28,"lastUpdatePostDateStruct":29,"startDateStruct":32,"completionDateStruct":34,"leadSponsor":36,"locationsCount":4},"100628376","serum-uric-acid-in-adolescents-with-primary-headache-a-case-control-study-100628376",false,"NCT07460830","Serum Uric Acid in Adolescents With Primary Headache: A Case-Control Study","Association Between Serum Uric Acid Levels and Primary Headaches in Adolescents: A Case-Control Study","Inclusion Criteria:\n\n* Inclusion Criteria (Cases):\n\nAdolescents aged 12-18 years presenting to pediatric neurology outpatient clinics\n\nDiagnosis of primary headache according to the International Classification of Headache Disorders, 3rd edition (ICHD-3) (e.g., 1.1, 1.2, etc.)\n\nDiagnosis confirmed by a pediatric neurologist following a comprehensive clinical evaluation\n\nSufficient cognitive ability to understand and complete study instruments\n\n* Inclusion Criteria (Controls):\n\nAdolescents aged 12-18 years presenting to general pediatric outpatient clinics\n\nNo history of recurrent headaches\n\nNo chronic medical or psychiatric disorders\n\nMatched with the case group for age and sex\n\nExclusion Criteria:\n\n* History of neurological disorders other than primary headache\n* Previously diagnosed psychiatric conditions\n* Autoimmune diseases, chronic infections, severe cardiac failure, metabolic or inflammatory disorders, obesity, or significant hepatic or renal impairment\n* Regular use of psychotropic medications or a history of polycythemia\n* Use of drugs known to affect uric acid metabolism within 2-4 weeks prior to enrollment\n* Cognitive or developmental disabilities limiting the ability to understand or complete study instruments","ALL","12 Years","18 Years",{"count":20,"type":21},80,"ESTIMATED","1 Day","OBSERVATIONAL","This observational, case-control study will evaluate differences in serum uric acid and related hematologic and biochemical parameters between adolescents (12-18 years) with primary headache and age-\u002Fsex-matched controls without recurrent headaches or chronic medical\u002Fpsychiatric disorders. Cases will meet International Classification of Headache Disorders, 3rd edition (ICHD-3) criteria verified by a pediatric neurologist after comprehensive clinical assessment. The study will also collect sociodemographic data and anthropometrics to calculate BMI. Primary outcome is the between-group difference in serum uric acid levels at enrollment. Secondary outcomes include group differences in ferritin, creatinine, BUN, complete blood count indices (Hb, WBC, neutrophils, lymphocytes, platelets, MPV), and BMI.",[26],"Primary Headache Disorders","NOT_YET_RECRUITING","2026-03-04",{"date":30,"type":31},"2026-03-10","ACTUAL",{"date":33,"type":21},"2026-03-15",{"date":35,"type":21},"2026-05-15",{"name":37,"class":38},"Konya Necmettin Erbakan Üniversitesi","OTHER",{"id":40,"slug":41,"hasResults":11,"nctId":42,"briefTitle":43,"officialTitle":44,"acronym":4,"eligibilityCriteria":45,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":46,"targetDuration":22,"studyType":23,"phases":4,"briefSummary":48,"conditions":49,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":52,"lastUpdatePostDateStruct":53,"startDateStruct":55,"completionDateStruct":56,"leadSponsor":58,"locationsCount":4},"100602494","the-impact-of-social-anxiety-on-adolescents-diagnosed-with-primary-headache-a-case-control-study-100602494","NCT07124234","The Impact of Social Anxiety on Adolescents Diagnosed With Primary Headache: A Case-control Study","Assessment of the Impact of Social Anxiety on Primary Headache in Adolescents: A Case-Control Study","Inclusion Criteria:\n\n* Adolescents aged 12-18 years\n* Case group: Participants who will be diagnosed with primary headache according to InternationalClassification of Headache Disorders, 3rd edition (ICHD-3) criteria, confirmed by a pediatric neurologist\n* Control group: Participants who will have no history of recurrent headache or chronic physical\u002Fpsychiatricillness\n\nExclusion Criteria:\n\n* History of neurological disease other than primary headache\n* Any previously diagnosed psychiatric disorders\n* Regular use of psychotropic medications\n* Cognitive or developmental disabilities that would interfere with assessments",{"count":47,"type":21},200,"This case-control study will examine whether adolescents aged 12-18 years with a diagnosis of primary headache are more likely to experience elevated social anxiety compared to matched healthy controls. Social anxiety will be assessed using the SAS-A, and the study will also explore whether environmental and sociodemographic factors such as tobacco smoke exposure, BMI, and parental education influence this relationship.",[50,51],"Primary Headache","Social Anxiety Disorder","2025-08-08",{"date":54,"type":31},"2025-08-15",{"date":54,"type":21},{"date":57,"type":21},"2025-10-15",{"name":37,"class":38},{"id":60,"slug":61,"hasResults":11,"nctId":62,"briefTitle":63,"officialTitle":64,"acronym":4,"eligibilityCriteria":65,"healthyVolunteers":66,"sex":16,"minAge":67,"maxAge":18,"enrollmentInfo":68,"targetDuration":4,"studyType":70,"phases":71,"briefSummary":73,"conditions":74,"keywords":76,"overallStatus":80,"whyStopped":4,"lastUpdateSubmitDate":81,"lastUpdatePostDateStruct":82,"startDateStruct":84,"completionDateStruct":86,"leadSponsor":88,"locationsCount":89},"100595353","marpe-associated-changes-in-sleep-and-airway-100595353","NCT07031349","MARPE-Associated Changes in Sleep and Airway","Evaluation of Changes in Upper Airway Dimensions and Subjective Sleep Quality Following Miniscrew-Assisted Rapid Palatal Expansion: A Questionnaire-Based Study","Inclusion Criteria:\n\nClass I malocclusion Maxillary transverse deficiency Age between 15 and 18 years No systemic disease, cleft lip and palate, or speech disorders No history of prior orthodontic treatment Voluntary agreement to participate in the study Good oral hygiene ANB angle between 2° and 5°\n\nExclusion Criteria:\n\nPresence of systemic diseases Smoking Poor oral hygiene Lack of cooperation Mental retardation Obesity or nutritional disorders Macroglossia or mandibular retrognathia",true,"15 Years",{"count":69,"type":21},40,"INTERVENTIONAL",[72],"NA","At the beginning of MARPE treatment (T1) and at the end of the 3-month consolidation phase (T2), patients will complete the teen-STOP-BANG questionnaire and the Pittsburgh Sleep Quality Index (PSQI) to assess the potential benefit of MARPE in reducing the risk of obstructive sleep apnea syndrome (OSAS).\n\nAdditionally, changes in the upper airway will be evaluated using CBCT images obtained at T1 and T2.",[75],"Rapid Maxillary Expansion",[77,78,79],"MARPE","STOP-BANG","PSQI","RECRUITING","2025-06-21",{"date":83,"type":31},"2025-06-26",{"date":85,"type":31},"2025-05-30",{"date":87,"type":21},"2025-09-05",{"name":37,"class":38},1,""]