[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Korea University\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":168},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,5,0,[8,62,98,122,143],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":20,"enrollmentInfo":21,"targetDuration":4,"studyType":24,"phases":25,"briefSummary":27,"conditions":28,"keywords":32,"overallStatus":49,"whyStopped":4,"lastUpdateSubmitDate":50,"lastUpdatePostDateStruct":51,"startDateStruct":54,"completionDateStruct":56,"leadSponsor":58,"locationsCount":61},"100606449","ultra-processed-food-reducing-intervention-and-continuous-glucose-monitoring-100606449",false,"NCT07175701","Ultra-processed Food-reducing Intervention and Continuous Glucose Monitoring","Effects of Ultra-processed Food Reduction Intervention on Postprandial Glucose and Glycemic Variability in Korean Young Adults: Study Protocol for the ULTRA-CGM Randomized Controlled Trial","ULTRA-CGM","Inclusion Criteria:\n\n1. Korean adults aged 20-39 years\n2. Not currently pregnant\n3. No personal history of diabetes or other glucose-related conditions\n4. Consume ≥25% of daily energy intake from UPFs, as assessed by an online, self-administered semi-quantitative screening food frequency questionnaire (FFQ)\n5. No restriction on wearing a CGM device\n6. No increased risk of bleeding\n7. No prior adverse reaction to CGM devices\n8. Willingness to participate in follow-up assessments\n\nExclusion Criteria:\n\n1. Unable to maintain continuous follow-up during the study period (e.g., due to special plans such as traveling)\n2. Planning to follow a special or restrictive diet (e.g., for weight loss) during the study period",true,"ALL","20 Years","39 Years",{"count":22,"type":23},50,"ESTIMATED","INTERVENTIONAL",[26],"NA","The goal of this trial is to investigate whether reduction in ultra-processed food intake through dietary counseling and education can improve postprandial glucose responses and glycemic variability compared with a usual diet in young, healthy Korean adults aged 20-30 years. The main questions it aims to answer are:\n\n\\- Does reducing ultra-processed food intake, while maintaining total energy intake and usual lifestyle behaviors, improve postprandial glucose and lower glycemic variability in healthy adults without diabetes?\n\nParticipants will:\n\n* Undergo the 10-day pre-intervention monitoring period, during which each participant will wear a continuous glucose monitoring (CGM) device and concurrently report their daily dietary intakes (all food and beverage consumption) and other lifestyle behaviors (sleep, smoking, physical activity)\n* After the 10-day pre-intervention monitoring period, participants will be randomized to either intervention or control group\n* Intervention group: Participants will visit the research site to receive dietitian-led one-on-one nutrition education and personalized dietary counseling targeting reduction of ultra-processed food intake. Personalized diet counseling will be provided by study dietitian based on participant's records of dietary intakes during the 10-day pre-intervention monitoring period.\n* Control group: Participants will receive dietitian-led nutrition education and personalized dietary counseling based on the national dietary guidelines.\n* After the intervention, participants will undergo the 10-day post-intervention monitoring period, during which participants will wear a new CGM device for an additional 10 days and continue daily reporting of dietary intakes (all food and beverage consumptions) and lifestyle behaviors (sleep, smoking, physical activity).",[29,30,31],"Postprandial Glucose","Glucose Levels","Hyperglycemias",[33,34,35,36,37,38,39,40,41,42,43,44,45,46,47,48],"ultra-processed food","continuous glucose monitoring","processed food","glucose","glycemic variability","glycemic control","hyperglycemia","glucose intolerance","Food Additives","flavoring agents","sweetening agents","non-nutritive sweeteners","nutritive sweeteners","high fructose corn syrup","food coloring agents","food preservatives","RECRUITING","2026-04-13",{"date":52,"type":53},"2026-04-17","ACTUAL",{"date":55,"type":53},"2025-10-11",{"date":57,"type":23},"2026-08-31",{"name":59,"class":60},"Korea University","OTHER",1,{"id":63,"slug":64,"hasResults":11,"nctId":65,"briefTitle":66,"officialTitle":67,"acronym":68,"eligibilityCriteria":69,"healthyVolunteers":17,"sex":18,"minAge":70,"maxAge":4,"enrollmentInfo":71,"targetDuration":4,"studyType":73,"phases":4,"briefSummary":74,"conditions":75,"keywords":80,"overallStatus":49,"whyStopped":4,"lastUpdateSubmitDate":90,"lastUpdatePostDateStruct":91,"startDateStruct":93,"completionDateStruct":95,"leadSponsor":97,"locationsCount":61},"100630262","global-collaborative-research-on-establishing-a-korean-cognitive-aging-cohort-100630262","NCT07485387","Global Collaborative Research on Establishing a Korean Cognitive Aging Cohort","Global Collaborative Research on Establishing a Korean Cognitive Aging Cohort That is Associated With the Einstein Aging Study","KoCoA cohort","Inclusion Criteria:\n\n* Adults aged 60 or older residing in the Republic of Korea\n* Samsung Galaxy smartphone users capable of using smartphone applications\n* Sufficient cognitive ability to understand and follow research instructions (MMSE score of 21 or above)\n* For individuals who do not meet the cognitive criteria, those who understand the study procedures and provide informed consent along with their legal guardian\n\nExclusion Criteria:\n\n* Diagnosis of dementia at baseline\n* Severe visual or hearing impairments that prevent participation in psychological assessments\n* Illiteracy that prevents participation in cognitive testing\n* Less than 80% compliance with the 2-day preliminary EMA protocol (one additional attempt allowed after re-training)\n* Current alcohol or substance abuse\n* Inability to ambulate or psychiatric conditions that prevent survey participation\n* Currently undergoing cancer treatment or received chemotherapy within the past 6 months","60 Years",{"count":72,"type":23},180,"OBSERVATIONAL","The goal of this observational study is to learn how daily emotional stress affects cognitive function and inflammation in community-dwelling older adults aged 60 and older in Seoul, Republic of Korea. The main questions it aims to answer are:\n\nDoes daily psychological stress measured in real-time affect short-term and long-term cognitive function in older adults? Do pro-inflammatory cytokines (such as CRP, IL-6, IL-10, and TNF-α) mediate the relationship between emotional stress and cognitive decline? How do social support and social isolation influence cognitive function and inflammatory biomarkers over time?\n\nParticipants will:\n\nComplete baseline surveys assessing depression, cognitive function, and personal characteristics Use a smartphone app to answer brief surveys about their emotions, cognitive performance, and social interactions 1-6 times daily for two weeks Wear a Galaxy Watch to track sleep quality, heart rate, and physical activity Provide blood samples for inflammatory biomarker analysis Return for follow-up assessments at 6 months and 1 year\n\nThis study is part of an international collaboration to establish a Korean cohort comparable to the U.S. Einstein Aging Study, with the aim of developing culturally tailored dementia prevention strategies.",[76,77,78,79],"Mild Cognitive Impairment (MCI)","Dementia Alzheimer Type","Chronic Pain","Depression - Major Depressive Disorder",[81,82,83,84,85,86,87,88,89],"mild cognitive impairment","dementia","chronic pain","depression","cognitive aging","longitudinal cohort","digital biomarkers","dementia biomarkers","behavioral phenotyping","2026-03-16",{"date":92,"type":53},"2026-03-20",{"date":94,"type":53},"2025-04-01",{"date":96,"type":23},"2037-12-31",{"name":59,"class":60},{"id":99,"slug":100,"hasResults":11,"nctId":101,"briefTitle":102,"officialTitle":103,"acronym":4,"eligibilityCriteria":104,"healthyVolunteers":11,"sex":18,"minAge":105,"maxAge":106,"enrollmentInfo":107,"targetDuration":4,"studyType":24,"phases":109,"briefSummary":110,"conditions":111,"keywords":4,"overallStatus":113,"whyStopped":4,"lastUpdateSubmitDate":114,"lastUpdatePostDateStruct":115,"startDateStruct":117,"completionDateStruct":119,"leadSponsor":121,"locationsCount":4},"100621879","executive-function-intervention-for-children-with-asd-combining-a-digital-app-and-parent-coaching-100621879","NCT07376356","Executive Function Intervention for Children With ASD Combining a Digital App and Parent Coaching","A Randomized Controlled Trial of Executive Function Intervention for Children With Autism Spectrum Disorder(ASD) Combining Digital Application and Parent Coaching","Inclusion Criteria:\n\n* Children in South Korea aged 5-8\n* Children with previous medical diagnosis of ASD or children categorized as \"Autism\" or \"Autism Spectrum\" after administering ADOS-2\n* Children with language abilities that meet the eligibility for ADOS-2 Module 2 or 3\n* Children with cognitive functioning assessed using the Wechsler Preschool and Primary Scale of Intelligence and a nonverbal IQ of 70 or above\n\nExclusion Criteria:\n\n* Children with significant intellectual disability\n* Children with significant language delay","5 Years","8 Years",{"count":108,"type":23},40,[26],"The purpose of this randomized controlled study is to develop and evaluate a digital cognitive control intervention that integrates a digital application-based child training program with an online parent coaching program for early school-aged children aged 5-8 with autism spectrum disorder (ASD) and their caregivers in South Korea. This intervention is designed to enhance clinical applicability, sustainability, and generalization to daily life of executive skills through active parental involvement. This study has three primary aims: (1) to examine the feasibility, acceptability, and implementation fidelity of the integrated child-parent digital intervention, (2) to investigate the effects of the intervention on children's cognitive control and executive function using behavioral assessments and neurophysiological measures (e.g., EEG), as well as on parents' use of cognitive control-supportive strategies in daily contexts, and (3) to assess whether intervention related changes generalize to real-world functioning, including children's adaptive behavior, academic readiness, and social functioning, as reported by parents, and whether these effects are maintained over time.",[112],"Autism Spectrum Disorder","NOT_YET_RECRUITING","2026-01-28",{"date":116,"type":53},"2026-01-30",{"date":118,"type":23},"2026-02",{"date":120,"type":23},"2027-08",{"name":59,"class":60},{"id":123,"slug":124,"hasResults":11,"nctId":125,"briefTitle":126,"officialTitle":127,"acronym":4,"eligibilityCriteria":128,"healthyVolunteers":11,"sex":18,"minAge":129,"maxAge":130,"enrollmentInfo":131,"targetDuration":4,"studyType":24,"phases":132,"briefSummary":133,"conditions":134,"keywords":4,"overallStatus":113,"whyStopped":4,"lastUpdateSubmitDate":135,"lastUpdatePostDateStruct":136,"startDateStruct":138,"completionDateStruct":140,"leadSponsor":142,"locationsCount":4},"100618193","diagnosis-disclosure-support-for-caregivers-of-children-with-autism-100618193","NCT07328438","Diagnosis Disclosure Support for Caregivers of Children With Autism","Diagnosis Disclosure Support Intervention Program for Caregivers of Children With ASD","Inclusion Criteria:\n\n* Caregivers of children aged 7-12 (Grades 2-6) attending mainstream schools in South Korea\n* Caregivers of children with previous medical diagnosis of ASD\n* Caregivers with no prior experience of participation in diagnosis disclosure support programs\n* Caregivers in agreement with the need for a ASD diagnosis disclosure support intervention program, with commitment to continuous and sincere participation\n\nExclusion Criteria:\n\n* Caregivers of children with significant intellectual disability\n* Caregivers of children with significant language delay","7 Years","12 Years",{"count":108,"type":23},[26],"The purpose of this randomized controlled pilot study is to develop and evaluate an online diagnosis disclosure support intervention for caregivers of 7- to 12-year-old children with autism spectrum disorder (ASD) in South Korea. This intervention is designed to support caregivers who are contemplating, preparing for, or carrying out disclosure of their child's ASD diagnosis to the child. This study has three primary aims: (1) to evaluate the acceptability and feasibility of the intervention; (2) to examine clinically meaningful effects of the intervention on caregivers' psychological well-being and psychosocial adjustment (e.g., emotion regulation, loneliness\u002Fsocial isolation, and adaptation to life transitions), parenting competence and attitudes (e.g., parenting self-efficacy, parenting role satisfaction, and parenting stress), and autism-related knowledge and social perceptions (e.g., autism knowledge and perceived autism-related stigma); and (3) to assess whether the effects of the intervention are maintained one month after program completion.",[112],"2026-01-18",{"date":137,"type":53},"2026-01-21",{"date":139,"type":23},"2026-01-05",{"date":141,"type":23},"2027-04-30",{"name":59,"class":60},{"id":144,"slug":145,"hasResults":11,"nctId":146,"briefTitle":147,"officialTitle":148,"acronym":149,"eligibilityCriteria":150,"healthyVolunteers":11,"sex":18,"minAge":151,"maxAge":4,"enrollmentInfo":152,"targetDuration":4,"studyType":73,"phases":4,"briefSummary":154,"conditions":155,"keywords":158,"overallStatus":113,"whyStopped":4,"lastUpdateSubmitDate":160,"lastUpdatePostDateStruct":161,"startDateStruct":163,"completionDateStruct":165,"leadSponsor":167,"locationsCount":5},"100580908","korean-health-screening-based-metabolic-dysfunction-associated-steatotic-liver-disease-registry-100580908","NCT06843421","Korean Health Screening-Based Metabolic Dysfunction-Associated Steatotic Liver Disease Registry","Korean Health Screening-Based Metabolic Dysfunction-Associated Steatotic Liver Disease Registry: A Retrospective Multicenter Cross-Sectional Study (K-MASLD Registry)","K-MASLD","Inclusion Criteria:\n\n* An individual who had an abdominal ultrasound performed\n\nExclusion Criteria:\n\n* An individual with high alcohol intake history or other liver disease","19 Years",{"count":153,"type":23},6000,"The goal of this observational study is to establish a multi-center registry to better understand Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) using health screening data from Korean hospitals. MASLD is a liver condition where excess fat builds up in the liver and is closely linked to metabolic health problems like high blood pressure, diabetes, and obesity.\n\nThe main questions this study aims to answer are:\n\n* What are the characteristics of people with MASLD?\n* How is MASLD related to other health conditions, especially heart and blood vessel diseases?\n* What factors might help identify MASLD early?\n\nResearchers will compare two groups of people:\n\n* People who have MASLD\n* People who don't have MASLD (control group)\n\nThis study will look at health screening records from 2020 to 2023 from six Korean hospitals. The research team will collect and analyze:\n\n* Basic health information (age, gender, weight, height, waist size)\n* Lifestyle habits (drinking, smoking, exercise, eating habits)\n* Medical conditions (high blood pressure, diabetes, high cholesterol)\n* Results from medical tests including:\n\nLiver ultrasound and Fibroscan results Heart CT scans Blood vessel ultrasound Blood test results Other health screening results\n\nParticipants in this study will not need to do anything new. The researchers will only look at information that was already collected during regular health screenings. All personal information will be protected and kept private.\n\nThis research could help doctors:\n\n* Better understand who is at risk for MASLD\n* Find MASLD earlier\n* Develop better ways to prevent and treat MASLD\n* Understand how MASLD is connected to other health problems\n\nThe study will take place over 3 years and includes adults age 19 and older who had health screenings at participating Korean hospitals. People who drink large amounts of alcohol or have other liver diseases will not be included in the study.\n\nBy learning more about MASLD through this registry study, researchers hope to improve healthcare for people with or at risk for this liver condition.",[156,157],"Metabolic Dysfunction-Associated Steatotic Liver Disease","Cardiovascular Diseases",[156,159],"Cardiovascular disease","2025-02-25",{"date":162,"type":53},"2025-02-27",{"date":164,"type":23},"2025-03-01",{"date":166,"type":23},"2025-12-01",{"name":59,"class":60},""]