[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"La Tour Hospital\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":152},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,5,0,[8,50,74,104,130],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":44,"leadSponsor":46,"locationsCount":49},"100410813","anatomic-tsa-vs-rtsa-for-glenohumeral-arthritis-100410813",false,"NCT04629391","Anatomic TSA vs RTSA for Glenohumeral Arthritis","Anatomic Versus Reverse Shoulder Arthroplasty for Primary Glenohumeral Osteoarthritis. A Randomized Prospective Study","Inclusion Criteria:\n\n* Primary glenohumeral arthritis,\n* Intact rotator cuff,\n* No important glenoid bone loss (cf exclusion criteria),\n* Patients between 65 and 85 years old\n* Informed Consent as documented by signature (Appendix Informed Consent Form).\n\nExclusion Criteria:\n\n* B2 glenoid with \\> 80% posterior humeral head subluxation or greater 25 degrees neoglenoid retroversion,\n* B3 and C type glenoids,\n* Full thickness rotator cuff tear,\n* Acute or malunited proximal humeral fracture,\n* Chronic locked dislocation\n* Rheumatoid arthritis,\n* Revision surgery or surgical antecedents,\n* Tumors,\n* Axillary nerve damage,\n* Non-functioning deltoid muscle,\n* Glenoid vault deficiency precluding baseplate fixation,\n* Infection and neuropathic joints,\n* Known or suspected non-compliance, drug or alcohol abuse,\n* Patients incapable of judgement or under tutelage,\n* Inability to follow the procedures of the study, e.g. due to language problems, psychological disorders, dementia, contraindication for CT scan etc. of the participant,\n* Enrolment of the investigator, his\u002Fher family members, employees and other dependent persons.","ALL","65 Years","85 Years",{"count":20,"type":21},296,"ESTIMATED","INTERVENTIONAL",[24],"NA","There are no published prospective studies that compared 2-year functional outcomes of RTSA and anatomic TSA for the treatment of primary glenohumeral osteoarthritis with intact rotator cuffs and no excessive glenoid retroversion. The primary goal of our prospective randomized study is to determine whether RTSA have at least as good results as anatomic TSA (non-inferiority), in patients with glenohumeral osteoarthritis, without rotator cuff tears nor significant glenoid retroversion.",[27],"Arthritis Shoulder",[29,30,31,32,33,34,35,36],"shoulder","primary osteoarthritis","Range of motion","clinical outcomes","radiographic outcomes","anatomic prosthesis","reverse prosthesis","Arthroplasty","RECRUITING","2026-05-19",{"date":40,"type":41},"2026-05-22","ACTUAL",{"date":43,"type":41},"2020-09-01",{"date":45,"type":21},"2027-05-01",{"name":47,"class":48},"La Tour Hospital","OTHER",1,{"id":51,"slug":52,"hasResults":11,"nctId":53,"briefTitle":54,"officialTitle":55,"acronym":4,"eligibilityCriteria":56,"healthyVolunteers":11,"sex":16,"minAge":57,"maxAge":4,"enrollmentInfo":58,"targetDuration":4,"studyType":22,"phases":60,"briefSummary":61,"conditions":62,"keywords":4,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":49},"100590174","virtual-reality-rehabilitation-for-shoulder-pathologies-100590174","NCT06963983","Virtual Reality Rehabilitation for Shoulder Pathologies","Personalized Rehabilitation System Using Gamification With Virtual Reality Technology: A Feasibility Study","Inclusion Criteria:\n\n* Adult patients able to understand the content of the patient information \u002F consent form and give consent to take part in the research project\n* Glenohumeral instability surgical treated with traumatic initial instability in a \\\u003C 20 years old athlete, recurrent instability with one or more of the following criteria: a failure of conservative treatment, locked dislocation, failed prior surgery, high risk for further recurrence (i.e. collision or competitive athletes), Critical glenoid bone-loss (\\>15-20%), bipolar bone-loss resulting in \"off-track\" lesion\n* Partial or complete rotator cuff repair with an indication to postoperative rehabilitation depending on surgeon recommendation\n* Idiopathic, primary, or secondary frozen shoulder\n\nExclusion Criteria:\n\n* Patients with a language barrier hindering questionnaires completion\n* Patients unlikely to attend clinical follow-up (e.g. when living abroad)\n* Legal incompetence\n* Enrolment of the investigators, his\u002Fher family members, employees and other dependent persons\n* Non-motivated patients\n* Active infection\n* Exclusion criteria related to glenohumeral instability: uncontrolled epilepsy, spontaneous unidirectional instability in a hyperlax patient, multidirectional instability, elher-Danlos syndrome\n* Exclusion criteria related to rotator cuff tears: Additional procedure(s) (muscle transfer, patch,…)\n* Exclusion criteria related to VR use: Patients with a predisposition to motion sickness, Patients suffering from epilepsy or having any serious mental illness (schyzophrenia, neurological problems, etc.), Patients with visual impairment , Patients will intellectual disability that prevent them to understand how to use the VR rehabilitation system, Patients with bilateral upper limb injuries, as one side is needed as healthy reference","18 Years",{"count":59,"type":21},15,[24],"Most rehabilitation protocols require patients to train the affected limbs with high regularity, following repetitive cycles of exercises, in order to recover mobility and strength. Nonetheless, the repetitive nature of these exercises can demotivate patients leading to less intense and committed training, if not ending with a lack of compliance toward the prescribed exercises, ultimately leading to a suboptimal recovery. For this reason, several research groups are investigating solutions to help patients in this process, using robotic support or protocols assisted by virtual reality (VR).\n\nMost of these studies have shown benefits, notably in the field of post-stroke rehabilitation, however numerous types of physical therapies have not been investigated yet. Therefore, the main goal of this study will be to explore if the combination of modern motion-tracking and VR can provide significant functional outcomes for the treatment of the most common upper limb pathologies. The investigators created a set of exergames designed to lead the patients through a gamified version of part of physiotherapy (PT). This modified therapy is expected to offer several benefits to the treatment with respect to a purely conventional therapy: (i) improved patient's motivation and commitment to the exercises; (ii) constant evaluation of the patient's performance, thanks to the use of motion tracking; (iii) session-by-session tuning of exercises difficulty; (iv) clear progress traceability; (v) real-time alerts in case of problematic or compensatory movements; (vi) measurement and evaluation of new metrics of movements quality that were not possible in conventional therapy setups.\n\nTo evaluate the feasibility of this project, the investigators would like to test the VR system on a short series of patients during four sessions.",[63,64,65],"Shoulder Instability","Frozen Shoulder","Rotator Cuff Tears","2025-04-30",{"date":68,"type":41},"2025-05-09",{"date":70,"type":41},"2024-10-28",{"date":72,"type":21},"2025-06-28",{"name":47,"class":48},{"id":75,"slug":76,"hasResults":11,"nctId":77,"briefTitle":78,"officialTitle":79,"acronym":4,"eligibilityCriteria":80,"healthyVolunteers":11,"sex":16,"minAge":81,"maxAge":82,"enrollmentInfo":83,"targetDuration":4,"studyType":22,"phases":85,"briefSummary":86,"conditions":87,"keywords":89,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":95,"lastUpdatePostDateStruct":96,"startDateStruct":98,"completionDateStruct":100,"leadSponsor":102,"locationsCount":103},"100489969","treatment-of-the-biceps-with-concomitant-supraspinatus-tears-100489969","NCT05660031","Treatment of the Biceps With Concomitant Supraspinatus Tears","Treatment of the Biceps With Concomitant Supraspinatus Tears: A Multicenter Pragmatic Three-Arm Parallel-Group Randomized Surgical Trial","Inclusion Criteria:\n\n* Patient voluntarily consents to participate in the study and has the mental and physical ability to participate in the study, fill out subjective questionnaires, return for follow-up visits, and comply with prescribed post-operative physical therapy.\n* Full thickness tear of the supraspinatus tendon\n* Intact subscapularis tendon\n* Primary rotator cuff repair\n* Age 50-80\n\nExclusion Criteria:\n\n* Previous full thickness biceps tear\n* Infection and neuropathic joints\n* Known or suspected non-compliance, drug or alcohol abuse\n* Patients incapable of judgement or under tutelage\n* Inability to follow the procedures of the study, e.g. due to language problems, psychological disorders, dementia, contraindication for MRI scan etc.\n* Enrolment of the investigator, his\u002Fher family members, employees and other dependent persons\n* Patient declines to participate in study","50 Years","80 Years",{"count":84,"type":21},180,[24],"The long head of the biceps (LHB) tendon is thought to be a common source of shoulder pain and dysfunction in patients with rotator cuff pathology. Tenotomy and tenodesis have been shown to produce favourable and comparable results in treating LHB lesions, but a controversy still exists regarding the treatment of choice. Some suggest that tenotomy should be reserved for older, low-demand patients, while tenodesis should be performed in younger patients and those who engage in heavy labor. Proponents of tenotomy suggest that this is a technically easy procedure that leads to easy rehabilitation and fast return to activity with a low complication and reoperation rate. However, those who support LHB tenodesis list good preservation of elbow flexion and supination strength, improvement of functional scores, elimination of pain, and avoidance of cosmetic deformity as benefits of the procedure. Alternatively, the LHB can be maintained in the joint without tenodesis or tenotomy. In fact, it has not been clearly shown that LHB tenodesis or tenotomy leads to improved outcomes compared to leaving the biceps tendon intact.",[88],"Supraspinatus Tear",[90,91,92,93,94],"Long head of the biceps","Supraspinatus tear","tenotomy","tenodesis","rotator cuff repair","2025-04-23",{"date":97,"type":41},"2025-04-25",{"date":99,"type":41},"2021-06-01",{"date":101,"type":21},"2026-06-01",{"name":47,"class":48},4,{"id":105,"slug":106,"hasResults":11,"nctId":107,"briefTitle":108,"officialTitle":108,"acronym":109,"eligibilityCriteria":110,"healthyVolunteers":111,"sex":16,"minAge":57,"maxAge":81,"enrollmentInfo":112,"targetDuration":114,"studyType":115,"phases":4,"briefSummary":116,"conditions":117,"keywords":4,"overallStatus":121,"whyStopped":4,"lastUpdateSubmitDate":122,"lastUpdatePostDateStruct":123,"startDateStruct":125,"completionDateStruct":127,"leadSponsor":129,"locationsCount":4},"100576266","activation-failure-of-knee-extensors-after-anterior-cruciate-ligament-rupture-depending-on-the-contraction-mode-100576266","NCT06783062","Activation Failure of Knee Extensors After Anterior Cruciate Ligament Rupture Depending on the Contraction Mode","QUADFAIL","Inclusion Criteria:\n\nA. ACL-injured groups (surgically or conservatively treated):\n\n1. Age between 18 and 50 years\n2. Free, informed consent signed by the participant and the investigator.\n3. Session 1: Delay of 2 to 6 weeks after injury, with a quiet knee (range of motion 110- 0°, minimal effusion, maximal contraction pain ≤ 2\u002F10)\n4. Session 2: Duration of 36 to 42 weeks after injury, with a quiet knee (range of motion 110-0°, minimal effusion, maximal contraction pain ≤ 2\u002F10)\n5. Independent person (Unprotected: under guardianship, curatorship or other legal protection, deprived of liberty by judicial or administrative decision)\n\nB. ControlGroup:\n\n1. Age between 18 and 50 years\n2. Free, informed consent signed by the participant and the investigator.\n3. Sport practitioners: at least once per week practicing activities like collective sports, racket sports, combat sports, skiing, or on-loading activities with changing of directions.\n4. Independent person (Unprotected: under guardianship, curatorship or other legal protection, deprived of liberty by judicial or administrative decision)\n\nExclusion Criteria:\n\n* 1\\. Subjects fitted with an implanted electronic device such as a cardiac pacemaker 2. Professional athlete 3. Pregnant women 4. Subject with systemic pathology or treatment affecting the musculoskeletal system 5. Subject with a history of neurological pathology or traumatic pathology, or pathology that required orthopedic treatment and\u002For surgery of the knee, hip and\u002For lumbar spine 6. Contraindication to isokinetic testing: incapacitating pain, evolving pathological process, non- healed fracture, unbalanced cardiovascular pathology (angina pectoris, arterial hypertension) 7. Contralateral knee injury 8. Subject inability to follow procedures or insufficient knowledge of project language 9. Data acquisition issue or injury during testing",true,{"count":113,"type":21},60,"9 Months","OBSERVATIONAL","The primary objective of the study is to evaluate the impact of ACL injury and ACL reconstruction on voluntary activation during maximal voluntary contraction (measured by neurophysiological parameters) according to the contraction mode.\n\nThe goal is to provide elements of knowledge to clinicians about the mechanisms of the activation failure depending on contraction mode, but also the resulting adapted clinical recommendations for conducting rehabilitation, and particularly for the use of different contraction modes.\n\nThe main hypothesis is that activation failure is not equal according to the contraction mode during maximal voluntary contractions and neurophysiological parameters will be decreased in comparison with non-injured subjects.\n\nSecondary objectives are:\n\n* To analyze the evolution of neurophysiological parameters between sessions interspaced by several months according to the contraction mode.\n* To observe this time evolution depending on the treatment strategy chosen: rehabilitation or surgery plus rehabilitation.",[118,119,120],"ACL - Anterior Cruciate Ligament Rupture","Activation Failure","Contraction Mode","NOT_YET_RECRUITING","2025-01-14",{"date":124,"type":41},"2025-01-20",{"date":126,"type":21},"2025-02",{"date":128,"type":21},"2027-12",{"name":47,"class":48},{"id":131,"slug":132,"hasResults":11,"nctId":133,"briefTitle":134,"officialTitle":135,"acronym":4,"eligibilityCriteria":136,"healthyVolunteers":11,"sex":16,"minAge":137,"maxAge":82,"enrollmentInfo":138,"targetDuration":4,"studyType":22,"phases":140,"briefSummary":141,"conditions":142,"keywords":4,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":143,"lastUpdatePostDateStruct":144,"startDateStruct":146,"completionDateStruct":148,"leadSponsor":150,"locationsCount":151},"100501330","rsa-vs-rcr-for-massive-rcts-100501330","NCT05807854","RSA Vs RCR for Massive RCTs","Treatment of Degenerative Massive Rotator Cuff Tears: a Multicenter, Randomized Comparative Surgical Trial","Inclusion Criteria:\n\n* 1 Patient voluntarily consents to participate\n* 2 Patient with a massive and reparable non traumatic rotator cuff tears after failure of conservative treatment\n* 3 Patients with the following pre-operative images: Three standardized X-rays series and Magnetic Resonance Imaging (MRI) or arthro Magnetic Resonance Imaging without sign of traumatic lesions\n\nExclusion Criteria:\n\n* 1 Patient has known intentions, obligations, or co-morbidity that would inhibit them from participating in the study\n* 2 Revision rotator cuff repair\n* 3 Patient consent withdrawal\n* 4 Glenohumeral arthritis defined as stage \\> 3 Hamada classification\n* 5 Infection and neuropathic joints\n* 6 Known or suspected non-compliance, drug or alcohol abuse\n* 7 Patients incapable of judgement or under tutelage\n* 8 Inability to follow the procedures of the study\n* 9 Enrolment of the investigator, his\u002Fher family members, employees and other dependent persons","60 Years",{"count":139,"type":21},160,[24],"Different treatment options are available for massive or irreparable rotator cuff tears. An arthroscopic or an open repair approach is possible in the majority of cases and functional outcomes are improved, particularly when a complete arthroscopic repair can be achieved. However, the healing rate of massive rotator cuff tears after repair may remain low and failure of healing is associated with progression of arthritis. An alternative to arthroscopic or open repair is reverse shoulder arthroplasty which decreases pain and improves function, active shoulder elevation and quality of life. The primary goal of this prospective multicentric randomized study is to determine if there is a difference of functional outcomes between rotator cuff repair (RCR) repair and reverse shoulder arthroplasty (RSA).",[65],"2024-10-23",{"date":145,"type":41},"2024-10-26",{"date":147,"type":41},"2023-03-01",{"date":149,"type":21},"2027-03-01",{"name":47,"class":48},2,""]