[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Liberating Technologies, Inc.\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":100},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,40,71],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":17,"targetDuration":4,"studyType":20,"phases":21,"briefSummary":23,"conditions":24,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":28,"lastUpdatePostDateStruct":29,"startDateStruct":32,"completionDateStruct":34,"leadSponsor":36,"locationsCount":39},"100598723","caesar-foot-take-home-validation-testing-100598723",false,"NCT07075198","Caesar Foot Take-Home Validation Testing","Inclusion Criteria:\n\n* Have transtibial limb absence of one or both limbs\n* Express interest in running, but do not currently have a running blade (as determined by self-report)\n* Are at least 18 years of age\n* Are at least six months post amputation\n* Are classified as K3 or K4 ambulator status as determined by a certified prosthetist\n* Have an AMP score of at least 37\n* Are capable of running safely as determined by a certified prosthetist's clinical judgement\n* Have a well-fitting socket as determined by a certified prosthetist\n* Have adequate clearance between distal end of the residual limb and ground for the Caesar foot\n* Meets the foot size and weight class of one of the available Caesar prototypes\n\nExclusion Criteria:\n\n* Present or sustained injuries to residual limb or contralateral leg affecting functional ability\n* Non-English speaking participants will be excluded from this study due to limited access to interpreter services. These services would be needed for several visits, including training to learn how to use the device safely, along with requested verbal feedback from the participant to evaluate the design and usability of the system.\n* Using a prosthetic foot that an individual is unfamiliar with for higher activity tasks may increase the risk of falling. Therefore, pregnant women should not participate in the study and will be screened by self-disclosure.\n\nIndividuals can be excluded at the discretion of the investigator for other unforeseen disqualifying criteria (such as specific cognitive issues, etc.).","ALL","18 Years",{"count":18,"type":19},18,"ESTIMATED","INTERVENTIONAL",[22],"NA","The rationale for this study is to conduct a take-home clinical trial to evaluate the impact of the bimodal Caesar foot in a real-world environment. Participants will take the device home and use it throughout their daily life for two months. A one-month baseline period, using their usual foot, will be completed both before and after the two-month period with the Caesar foot condition. Self-report surveys and performance-based measures will be collected in the clinic at the end of each condition. The intent of this study is to determine the Caesar foot's feasibility in a real-world environment. Data will be collected to understand impact to the user's daily life and physical activity through outcomes and participant feedback. The feedback obtained during this study will be essential to informing the design intended for commercialization.",[25,26],"Prosthesis User","Lower Limb Amputation Below Knee (Injury)","RECRUITING","2025-10-09",{"date":30,"type":31},"2025-10-14","ACTUAL",{"date":33,"type":19},"2025-10",{"date":35,"type":19},"2026-08",{"name":37,"class":38},"Liberating Technologies, Inc.","INDUSTRY",1,{"id":41,"slug":42,"hasResults":11,"nctId":43,"briefTitle":44,"officialTitle":45,"acronym":4,"eligibilityCriteria":46,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":47,"targetDuration":4,"studyType":20,"phases":49,"briefSummary":50,"conditions":51,"keywords":57,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":63,"lastUpdatePostDateStruct":64,"startDateStruct":66,"completionDateStruct":67,"leadSponsor":69,"locationsCount":70},"100593821","effects-of-myoelectric-channel-count-and-targeting-for-upper-limb-prosthetic-control-100593821","NCT07011420","Effects of Myoelectric Channel Count and Targeting for Upper Limb Prosthetic Control","Evaluation of Functional Performance of Persons With Limb Differences to Optimize Pattern Recognition Control of Powered Upper Limb Prosthesis","Inclusion Criteria:\n\n* Unilateral transradial level limb absence\n* Current or past user of myo-electric controlled prostheses\n* Six months or more post-amputation\n* Have adequate limb length such that a wrist rotation device can fit in the check socket\n* Well-fitting socket as determined by a Socket-Comfort Score of 6 or above\n* Capable of wearing and operating a prosthesis with a wrist rotator and multi-articulating hand\n* Capable of understanding and following multi-step instructions and completing the tasks as described\n* English speaking\n\nExclusion Criteria:\n\n* Significant new injury that would prevent use of a prosthesis: The ability to consistently wear a prosthesis and perform activities of daily living and specific performance tasks is necessary to evaluate the relative benefits of the interventions.\n* Cognitive impairment sufficient to adversely affect understanding of or compliance with study requirements, ability to communicate experiences, or ability to give informed consent: The ability to understand and comply with requirements of the study is essential for the study to generate useable, reliable data. The ability to obtain relevant user feedback through questionnaires and informal discussion adds significant value to this study.",{"count":48,"type":19},32,[22],"The goal of this clinical trial is to systematically evaluate whether or not two commonly held fundamental assumptions for pattern recognition control translates to functional performance when tested on individuals aged 18 years or older with upper limb absence at the transradial level while wearing a physical prosthesis.\n\nThe specific aims of this study are:\n\n1. To evaluate the effect of changing untargeted myoelectric channel count on the functional performance of transradial prosthesis users wearing a fully functional prosthesis via functional outcomes measures such as the Box and Blocks test.\n2. To evaluate the effect of changing myoelectric channel targeting of a fixed number of myoelectric channels on the functional performance of transradial prosthesis users wearing a fully functional prosthesis via functional outcomes measures such as the Box and Blocks test.\n\nResearchers will perform a randomized crossover study to compare system configurations with different number of sensor channels and with various strategies for sensor placement on the limb. Participants will be assigned to a random test sequence that includes the following four different EMG channel conditions:\n\nCondition A: 4 untargeted channels Condition B: 8 untargeted channels Condition C: Up to 16 untargeted channels Condition D: 8 targeted channels\n\nResearchers will evaluate the effects of changing myoelectric channel counts on the functional prosthesis performance of individuals with transradial limb loss via functional outcome measures.\n\nParticipants will:\n\n* Attend up to 5 in-lab sessions that are expected to last 4 hours.\n* Conduct site visits every 1-2 weeks to complete functional and self reported outcome measures with each condition.\n* Play virtual games with the Coapt Cuff for 15 minutes a day, 3 days a week in between visits.",[52,53,54,25,55,56],"Amputation","Amputation, Traumatic","Amputation, Congenital","Upper Limb Amputation Below Elbow (Injury)","Amputation; Traumatic, Arm: Forearm, Between Elbow and Wrist",[58,59,60,61,62],"amputee","upper limb amputee","transradial amputee","prosthetic arm","upper limb prosthesis user","2025-09-02",{"date":65,"type":31},"2025-09-03",{"date":33,"type":19},{"date":68,"type":19},"2026-06",{"name":37,"class":38},2,{"id":72,"slug":73,"hasResults":11,"nctId":74,"briefTitle":75,"officialTitle":76,"acronym":4,"eligibilityCriteria":77,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":78,"targetDuration":4,"studyType":20,"phases":80,"briefSummary":81,"conditions":82,"keywords":87,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":63,"lastUpdatePostDateStruct":94,"startDateStruct":95,"completionDateStruct":97,"leadSponsor":99,"locationsCount":39},"100531057","clinical-outcomes-with-non-powered-vs-powered-prosthetic-knees-by-k2-level-amputees-100531057","NCT06194838","Clinical Outcomes With Non-Powered vs. Powered Prosthetic Knees by K2-level Amputees","Clinical Outcomes Associated With At Home Use of Non-Powered vs. Powered Prosthetic Knees by K2-level Individuals With Transfemoral Amputations","Inclusion Criteria:\n\n* Are at least 18 years old\n* Transfemoral prosthesis user (limb absence between the knee and hip)\n* Current user of a mechanical knee\n* Regularly wears prosthesis at least 5 days per week\n* Have adequate clearance between distal end and ground for necessary knee and foot components\n* Current Medicare Functional Classification Level (K-Level) of 2 as determined by the healthcare team\n* Socket-Comfort Score: 6 or above to ensure adequate socket fit\n* Six months or more experience on a prosthesis\n* Body weight between 50kg and 116kg (110lbs - 256lbs)\n* Height between 1.2m and 1.95m (47.2in and 76.8in)\n* Has a phone to answer periodic study calls\n\nExclusion Criteria:\n\n* Present injuries to residual limb or contralateral leg affecting functional ability\n* Contralateral amputation proximal to MTP (metatarsophalangeal) joint\n* Socket issues\u002Fchanges in the last 6 weeks\n* Users with bone-anchored implants\n* Health or medical condition, diagnosis, or other cause that would prevent participant from effectively following study protocol, performing required outcome measures, and\u002For completing the study\n\nSubjects can be excluded at the discretion of the investigator for other unforeseen disqualifying criteria (such as specific cognitive issues, etc.).\n\nIf subjects experience a health or medical condition that leaves them immobile for more than 2 weeks, they may be given the option to restart the study condition upon recovery, as long as eligibility criteria is still met, and comparable baseline functionality is demonstrated with outcomes measures.\n\nUsing a knee that the subject is unfamiliar with may increase the risk of falling. Therefore, pregnant women should not participate in the study and will be screened by self-disclosure.",{"count":79,"type":19},26,[22],"The goal of this proposed project is to gather community-based data from the K2-level Transfemoral Amputee (TFA) population to aid in evidence-based prescription of powered prosthetic knees (i.e., choosing the right device to maximize the benefit for each patient). The investigators intend to use this trial data along with a concurrent study being conducted within the K3-K4 level population to guide the implementation of effective prescriptions towards those that can benefit most from a given device and limit prescription to those who would not see benefit in order to ensure the most judicious use of Department of Defense (DoD) and Veteran's Affairs healthcare dollars. The findings will also be shared with the research community to help drive the design of future devices by identifying what features and functions are most beneficial to which patient populations when the devices are used outside of the laboratory. In summary, more community-based data on how powered prosthetic knees compare with the current standard in TFA populations is needed to allow for improved clinical decision making and clinical outcomes.",[52,83,84,25,85,86],"Amputation; Traumatic, Leg, Lower","Limb; Absence, Congenital, Lower","Lower Limb Amputation Above Knee (Injury)","Amputation; Traumatic, Leg: Thigh, Between Hip and Knee",[58,88,89,90,91,92,93],"lower limb amputee","transfemoral amputee","prosthetic knee","power knee","mechanical knee","lower limb prosthesis user",{"date":65,"type":31},{"date":96,"type":31},"2023-09-12",{"date":98,"type":19},"2026-08-31",{"name":37,"class":38},""]