[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Lidian Chen\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":74},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,43],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":22,"conditions":23,"keywords":25,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":4},"100637450","validation-of-population-characteristics-and-dosage-prescriptions-for-cognitive-function-intervention-benefits-of-different-doses-of-tai-chi-in-elderly-patients-with-mild-cognitive-impairment-a-real-world-cross-sectional-study-100637450",false,"NCT07608510","Validation of Population Characteristics and Dosage Prescriptions for Cognitive Function Intervention Benefits of Different Doses of Tai Chi in Elderly Patients With Mild Cognitive Impairment: A Real-World Cross-Sectional Study","Real-World External Validation Study on Beneficiary Population Characteristics and Individualized Dose Prescription for Cognitive Improvement of Tai Chi Intervention in Elderly Patients With Mild Cognitive Impairment","Inclusion Criteria:\n\n* 1\\. Presence of mild cognitive impairment, not demented; 2. Age ≥ 60 years old; 3.Regular practice of standardized 24-form simplified Tai Chi for at least 6 months (consistent with the form used in the parent randomized controlled trials \\[RCTs\\]) ; 4.Informed consent and voluntary participation.\n\nExclusion Criteria:\n\n1. Geriatric Depression Scale score ≥ 9 points\n2. Cognitive impairment caused by other reasons, taking drugs, poisoning, etc;\n3. Suffer from severe musculoskeletal system diseases and other contraindications to exercise and are not suitable for Tai Chi training, such as those who suffer from stroke, Parkinson's disease, and have a history of lower limb arthritis, hip and knee joint replacement, etc;\n4. Patients with severe heart, liver, kidney failure, malignant tumors, and other major diseases;\n5. Individuals with visual\u002Fauditory impairments, writing\u002Freading impairments, illiteracy, etc. that affect training and evaluation;\n6. Individuals with uncontrolled hypertension (systolic blood pressure greater than 160mmHg or diastolic blood pressure greater than 100mmHg after medication);\n7. Participating in other experiments that influence this study. -","ALL","60 Years",{"count":19,"type":20},150,"ESTIMATED","OBSERVATIONAL","This is a companion real-world external validation study of two pre-registered parent randomized controlled trials (RCTs, protocol IDs: FujianUTCM-1 and FujianUTCM-2). We aim to validate the generalizability and clinical applicability of a pre-developed machine learning prediction model (for Tai Chi intervention cognitive benefit population characteristics and individualized dose prescription) in a real-world community-dwelling population.",[24],"Mild Cognitive Impairment (MCI)",[26,27,28,29,30],"mild cognitive impairment","taiji","machine learning","External Validation","Real-World Study","NOT_YET_RECRUITING","2026-05-24",{"date":34,"type":35},"2026-05-27","ACTUAL",{"date":37,"type":20},"2026-05-15",{"date":39,"type":20},"2027-03-31",{"name":41,"class":42},"Lidian Chen","OTHER",{"id":44,"slug":45,"hasResults":11,"nctId":46,"briefTitle":47,"officialTitle":48,"acronym":4,"eligibilityCriteria":49,"healthyVolunteers":11,"sex":16,"minAge":50,"maxAge":51,"enrollmentInfo":52,"targetDuration":4,"studyType":54,"phases":55,"briefSummary":57,"conditions":58,"keywords":60,"overallStatus":64,"whyStopped":4,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":73},"100583459","motor-cognitive-interactive-upper-limb-robot-rehabilitation-for-post-stroke-motor-dysfunction-100583459","NCT06876597","Motor-Cognitive Interactive Upper Limb Robot Rehabilitation for Post-Stroke Motor Dysfunction","Motor-Cognitive Interactive Upper Limb Rehabilitation Robot Intervention for Post-Stroke Motor Dysfunction: A Multicenter Randomized Controlled Study","Inclusion Criteria:\n\n1. Diagnosis of stroke confirmed by CT or MRI.\n2. Age between 40 and 80 years, with no gender restrictions.\n3. First-ever stroke with unilateral limb paralysis.\n4. Onset of stroke between 2 weeks and 6 months prior, with an FMA-UE score of 8-44.\n5. Willingness to participate and provide written informed consent.\n\nExclusion Criteria:\n\n1. History of neuromuscular diseases, malignant tumors, or other severe uncontrolled conditions, including cardiac, renal, or hepatic diseases.\n2. Seated balance score \\\u003C 2, or inability to maintain a sitting position for more than 60 minutes.\n3. Modified Ashworth Scale score \\> 2.\n4. Visual Analog Scale (VAS) score \\> 3 for hemiplegic shoulder pain.\n5. Boston Diagnostic Aphasia Examination score \\\u003C 3.\n6. Severe visual impairment preventing participation in upper limb robot-assisted rehabilitation training.\n7. Hamilton Depression Scale score \\>17, indicating moderate to severe depressive symptoms.\n8. Participation in other clinical trials that may interfere with the results of this study.","40 Years","80 Years",{"count":53,"type":20},1047,"INTERVENTIONAL",[56],"NA","This study aims to investigate the effects of motor-cognitive interactive robot-assisted training on improving upper limb motor dysfunction after stroke. By observing different combinations of motor and cognitive components in the training, the study will clarify the relationship between the proportion of motor and cognitive elements and the recovery of upper limb motor function. The goal is to optimize the training protocol for upper limb rehabilitation robots and enhance their therapeutic outcomes.\n\nParticipants will be randomly assigned to one of three groups: motor-cognitive interactive robot-assisted training, motor-focused robot-assisted training, or conventional rehabilitation training. Training sessions will last 60 minutes, occur 5 times per week, and continue for 4 weeks. Researchers will measure changes in upper limb function and monitor for any adverse events during the training.",[59],"Stroke",[61,62,63],"upeer","motor-cognitive interaction","robot","RECRUITING","2025-04-22",{"date":67,"type":35},"2025-04-24",{"date":69,"type":35},"2025-04-08",{"date":71,"type":20},"2026-12-31",{"name":41,"class":42},1,""]