[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Lifecord Otd\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":39},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":28,"lastUpdatePostDateStruct":29,"startDateStruct":32,"completionDateStruct":34,"leadSponsor":36,"locationsCount":4},"100644491","anchord-mitral-chordal-repair-system---fih-100644491",false,"NCT07671820","Anchord Mitral Chordal Repair System - FIH","Anchord Mitral Chordal Repair System for Patients With Degenerative Mitral Regurgitation","Inclusion Criteria:\n\n* Severe symptomatic degenerative mitral regurgitation (grade 3+)\n* High surgical risk for open-heart mitral valve repair or replacement\n* Suitable anatomy for transcatheter chordal repair as determined by the treating physician\n* Ability to undergo required echocardiographic and fluoroscopic imaging\n* Ability to provide informed consent\n\nExclusion Criteria:\n\n* Active endocarditis or systemic infection\n* Severe left ventricular dysfunction (LVEF \\\u003C30%)\n* Significant non-mitral valvular disease requiring intervention\n* Severe mitral annular calcification (MAC)\n* Presence of intracardiac or femoral venous thrombus or thrombus in the inferior vena cava\n* Cerebrovascular events (TIA, CVA) or thromboembolic events within the previous 6 months.\n* Renal insufficiency\n* Inability to undergo required imaging or access\n* Inability to tolerate standard anticoagulation or antithrombotic regimen\n* Rheumatic mitral valve disease\n* Co-morbid condition limiting life expectancy or study completion\n* Pregnancy\n* Participation in another clinical trial\n* Previous device treatment for MR.","ALL","18 Years",{"count":19,"type":20},5,"ESTIMATED","INTERVENTIONAL",[23],"NA","The goal of this clinical trial is to generate initial human clinical experience and evaluate procedural feasibility, device deployment, and early safety under controlled First-In-Human conditions for the Anchord Mitral Chordal Repair System in patients with degenerative mitral regurgitation. The main question\\[s\\] it aims to answer are to assess the safety of procedure, the reduction in mitral regurgitation severity and changes in hemodynamic and symptomatic status.\n\nParticipants will be implanted with the Anchord device.",[26],"Mitral Regurgitation","NOT_YET_RECRUITING","2026-06-23",{"date":30,"type":31},"2026-06-26","ACTUAL",{"date":33,"type":20},"2026-07",{"date":35,"type":20},"2028-12",{"name":37,"class":38},"Lifecord Otd","INDUSTRY",""]