[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Lille University\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":187},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,6,0,[8,41,73,107,135,162],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":26,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":29,"lastUpdatePostDateStruct":30,"startDateStruct":33,"completionDateStruct":35,"leadSponsor":37,"locationsCount":40},"100644422","exploration-of-processes-involved-in-dissociative-identity-disorder-did-100644422",false,"NCT07663890","EXPLOration of Processes Involved in Dissociative Identity Disorder (DID)","EXPLOration Des Processus à l'Origine du Trouble Dissociatif de l'Identité (TDI)(EXPLOTDI)","EXPLO-DID","Inclusion Criteria:\n\n* Individuals who report having Dissociative Identity Disorder (DID)\n* At least 18 years old\n* Currently receiving treatment from a therapist (psychologist or psychiatrist)\n\nExclusion Criteria:\n\n* Individuals under guardianship or court-ordered protection","ALL","18 Years",{"count":20,"type":21},60,"ESTIMATED","OBSERVATIONAL","Dissociative Identity Disorder (DID) is a psychological condition in which a person may feel as though they have multiple distinct personalities or identities. Today, this disorder is being discussed more and more, particularly among young people, partly due to its visibility on social media. However, researchers have observed that some individuals may mimic or exaggerate the symptoms, which makes it more difficult to understand the disorder.\n\nThe goal of this study is therefore to better understand:\n\n* in which situations these identity shifts occur\n* what people feel at that moment\n* and what happens next To do this, researchers will interview approximately 60 people, some with a diagnosed DID and others exhibiting simulated symptoms.\n\nParticipants will complete questionnaires and take part in an interview. The researchers will analyze:\n\n* the situations that trigger the changes\n* the associated thoughts and emotions\n* the behaviors\n* the consequences of these episodes\n\nThe ultimate goal is to better understand this disorder in order to:\n\n* improve care\n* and better distinguish between genuine cases and feigned ones",[25],"Dissociative Identity Disorder (DID)",[27],"Dissociative Identity Disorder","RECRUITING","2026-06-23",{"date":31,"type":32},"2026-06-26","ACTUAL",{"date":34,"type":32},"2026-06-04",{"date":36,"type":21},"2028-06-30",{"name":38,"class":39},"Lille University","OTHER",4,{"id":42,"slug":43,"hasResults":11,"nctId":44,"briefTitle":45,"officialTitle":46,"acronym":47,"eligibilityCriteria":48,"healthyVolunteers":11,"sex":17,"minAge":49,"maxAge":50,"enrollmentInfo":51,"targetDuration":4,"studyType":53,"phases":54,"briefSummary":56,"conditions":57,"keywords":59,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":64,"lastUpdatePostDateStruct":65,"startDateStruct":67,"completionDateStruct":69,"leadSponsor":71,"locationsCount":72},"100577834","effects-of-circadian-rhythm-on-glycemic-regulation-during-continuous-moderate-exercise-and-intense-intermittent-disease-in-adolescents-living-with-type-1-diabetes-100577834","NCT06803446","Effects of Circadian Rhythm on Glycemic Regulation During Continuous Moderate Exercise and Intense Intermittent Disease in Adolescents Living With Type 1 Diabetes","Effets du Rythme Circadien Sur la régulation glycémique Lors d'Exercices modérés Continus et Intermittents Intenses Chez Des Adolescents Vivant Avec le diabète de Type 1","CHRONODIAB1","Inclusion Criteria:\n\n* Children and adolescents aged 10 to 16;\n* Living with type 1 diabetes for at least 1 year with HbA1c less than or equal to 12%;\n* Socially insured ;\n* Having given their written consent to participate in the research, as well as that of their legal guardians;\n* Willing to comply with all research procedures and duration.\n\nExclusion Criteria:\n\n* Clinically significant microvascular complications: nephropathy (estimated glomerular filtration rate less than 40 ml\u002Fmin), neuropathy or severe proliferative retinopathy as assessed by the investigator;\n* Recent acute macrovascular event (\\\u003C 3 months), e.g. acute coronary syndrome or cardiac surgery;\n* Abnormal blood picture and\u002For anemia;\n* Current pregnancy;\n* Other serious medical condition likely to interfere with study participation or ability to complete exercise periods in the judgment of the investigator (e.g., orthopedic limitation);\n* Inability to receive informed information;\n* Inability to participate in the entire study;\n* Lack of social security coverage;\n* Refusal to sign the consent form.","10 Years","16 Years",{"count":52,"type":21},18,"INTERVENTIONAL",[55],"NA","Interventional research with minimal risks and constraints on the effects of circadian rhythm on glycemic regulation during intense moderate, continuous and intermittent exercise in adolescents living with type 1 diabetes",[58],"Type 1 Diabetes",[60,61,62,63],"adolescents","type 1 diabetes","glycemic regulation","circadian rhythm","2025-09-03",{"date":66,"type":32},"2025-09-04",{"date":68,"type":32},"2024-12-18",{"date":70,"type":21},"2026-12-19",{"name":38,"class":39},1,{"id":74,"slug":75,"hasResults":11,"nctId":76,"briefTitle":77,"officialTitle":78,"acronym":79,"eligibilityCriteria":80,"healthyVolunteers":81,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":82,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":84,"conditions":85,"keywords":91,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":98,"lastUpdatePostDateStruct":99,"startDateStruct":101,"completionDateStruct":103,"leadSponsor":105,"locationsCount":106},"100588658","assessment-of-cancer-related-post-traumatic-stress-in-patients-and-caregivers-in-the-year-following-diagnosis-and-identification-of-their-expectations-of-personalized-support---candystress-100588658","NCT06944262","Assessment of Cancer-related Post-traumatic Stress in Patients and Caregivers in the Year Following Diagnosis, and Identification of Their Expectations of Personalized Support - CANDYSTRESS","Évaluation de la détresse Post-traumatique Relative au Cancer Dans l'année Suivant le Diagnostic Chez Les Patients et Les Aidants et Identification de Leurs Attentes Envers un Accompagnement personnalisé","CANDYSTRESS","Inclusion Criteria:\n\nPart 1. Diagnosis of Ca-PTS\n\nPatient inclusion criteria:\n\n* Male or female, 18 years of age or older,\n* recently (\\\u003C4 months) diagnosed with breast, gynecological, testicular or digestive cancer at the time of the announcement visit (i.e., the announcement to the patient of the treatment plan after the initial multidisciplinary consultation meeting in the cancer center - in accordance with the Cancer Plan),\n* with cancer requiring oncological treatment,\n* starting oncology treatment at the Oscar Lambret Center,\n* with no Central Nervous System (CNS) metastases,\n* with a PRONOPALL score ≤3 (favorable prognosis group, Bourgeois et al., 2017) or expected survival greater than 6 months,\n* who have given signed consent to participate in the study and are covered by French social security,\n* able to identify a caregiver (i.e., a family member, friend or other person who has helped care for them since diagnosis).\n* equipped with a computer or tablet equipped with a webcam and an internet connection, for the online questionnaire - the webcam is only necessary if the participant wants the IGE to be present via video on the computer, if they prefer the video to be made over the phone, in which case they must also be equipped with a smartphone enabling video calls.\n\nInclusion criteria for caregivers:\n\n* Male or female, 18 years of age or older,\n* designated by the patient as their primary caregiver (i.e. \"a family member, friend or other person who has helped care for you since diagnosis\"),\n* have given their signed consent to participate in the study.\n* equipped with a computer or tablet equipped with a webcam and an internet connection, for the online questionnaire - the webcam is only necessary if the participant wishes the IGE to be present via video on the computer, if he\u002Fshe prefers the video to be made over the phone, in which case it is also necessary to be equipped with a smartphone enabling video calls.\n\nPart 2. Gathering expectations for personalized support and its components.\n\nIn addition, 3 types of focus groups will be set up remote :\n\nFocus groups with patients from local associations, as well as patient partners of the Oscar Lambret Center and patients from Part 1 if they are interested.\n\nInclusion criteria for patient focus groups:\n\n* Men or women of legal age who have or have had cancer,\n* Members of a local patient association or of the Oscar Lambret Center's \"patient partners\" committee,\n* Or have participated in part 1 (Ca-PTS screening, once the 3 steps have been completed),\n* Equipped with a computer or tablet with camera and internet connection,\n* Have given their consent to take part in the study.\n\nFocus group with caregivers from local associations as well as \"partner caregivers\" from the Oscar Lambret Center and caregivers from part 1 if they are interested.\n\nInclusion criteria for \"caregiver\" focus groups:\n\n* Men or women of full age who are, or have been, caregivers of a cancer patient,\n* members of a local caregivers' association,\n* or having participated in part 1 (Ca-PTS screening, once the 3 steps have been completed),\n* Equipped with a computer or tablet with camera and internet connection,\n* Having given their consent to take part in the study.\n\nFocus groups with hospital medical and paramedical staff as well as non-hospital caregivers involved in the medical in the medical and psychological follow-up of patients.\n\nInclusion criteria for caregiver focus groups:\n\n* Member of the medical and paramedical staff of the Oscar Lambret Center\n* Or non-hospital staff involved in the medical or psychological care of patients,\n* Professionals not involved in the present study,\n* Equipped with a computer or tablet with camera and internet connection\n* Having given their consent to participate in the study\n\nExclusion Criteria:\n\nPart 1. Diagnosis of Ca-PTS\n\nNon inclusion criteria for patients :\n\n* Patients with meningeal or cerebral metastases,\n* Patients with cancer recurrence,\n* Patients suffering from a psychiatric or neurological disorder likely to impair their ability to reason or judge (in particular psychotic disorder, autism spectrum disorder, intellectual disability),\n* Patients with a psychological or physical incapacity to answer questionnaires, certified by medical staff,\n* Patients subject to a custodial sentence, guardianship or protection of vulnerable adults,\n* Presence of CNS metastases (risk of cognitive impairment preventing completion of questionnaires).\n\nNon-inclusion criteria for caregivers:\n\n* Caregivers suffering from a psychiatric or neurological disorder likely to impair their ability to reason or exercise judgment judgment (in particular psychotic disorder, autism spectrum disorder intellectual disability), or for whom there is a suspicion (not there is a suspicion (no additional examination is prescribed to confirm this criterion, which remains self-declaratory).\n* Caregivers with a psychological or physical inability to answer questionnaires, or for whom there is a suspicion suspicion (no further tests are required to confirm this criterion which remains self-reported).\n* Caregivers subject to a custodial sentence, guardianship or protection guardianship or protection of vulnerable adults.\n\nPart 2. Collection of expectations for personalized support and its components.\n\nNon-inclusion criteria for patients and caregivers who participated in the screening part of the Ca-PTS :\n\n\\- Failure to complete all measurement times (T0, T1, T2)\n\nNon-inclusion criteria for focus groups (patients, caregivers): none",true,{"count":83,"type":21},350,"The impact of cancer on the lives of patients and their caregivers is undeniable. In addition to the potentially traumatic aspects (i.e., creating a very violent emotional shock) linked to the announcement of the disease and the various stages of the care pathway (effects of treatment, announcement of a cancer recurrence), even before the onset of the disease, patients and their caregivers may have been directly or indirectly confronted with traumatogenic events (e.g., childhood abuse, sudden death). They may therefore be more likely to develop a stress-related mental disorder in their lifetime. The question of the accumulation of traumatic events, the identification of groups of people at risk of developing symptoms of distress, and the management of these symptoms is therefore crucial. In addition, the mutual influence within the patient-caregiver dyad in terms of emotional adjustment, and its evolution throughout the cancer care pathway, are key elements to be considered in these issues.\n\nThe CandyStress project is based on a partnership with patients, their caregivers and carers to identify the needs of patient-caregiver dyads at risk of cancer-related post-traumatic stress disorder (Ca-PTS). Longitudinal screening for Ca-PTS in the year following cancer diagnosis will be carried out to identify the characteristics of at-risk dyads who could benefit from long-term support. The aim of this project is to identify the potential need for targeted support and the desired format of this support. This is a preliminary step in identifying needs and the context conducive to the implementation of personalized support, but in no way an evaluation of the effectiveness of an intervention.",[86,87,88,89,90],"Cancer","Healthcare Professionnals","Caregiver Distress","Caregiver","Caregiver Stress Syndrome",[92,93,94,95,96,97],"cancer","trauma","patients","caregivers","dyad","cancer-related post-traumatic stress disorder","2025-04-23",{"date":100,"type":32},"2025-04-25",{"date":102,"type":32},"2025-04-02",{"date":104,"type":21},"2028-02-02",{"name":38,"class":39},2,{"id":108,"slug":109,"hasResults":11,"nctId":110,"briefTitle":111,"officialTitle":112,"acronym":113,"eligibilityCriteria":114,"healthyVolunteers":11,"sex":17,"minAge":115,"maxAge":116,"enrollmentInfo":117,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":119,"conditions":120,"keywords":122,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":127,"lastUpdatePostDateStruct":128,"startDateStruct":130,"completionDateStruct":132,"leadSponsor":134,"locationsCount":72},"100587136","identification-of-specific-molecular-signatures-in-pediatric-adolescent-and-young-adult-rhabdomyosarcoma-through-spatial-proteome-analysis-using-mass-spectrometry-100587136","NCT06924463","Identification of Specific Molecular Signatures in Pediatric, Adolescent, and Young Adult Rhabdomyosarcoma Through Spatial Proteome Analysis Using Mass Spectrometry","Identification de Signatures moléculaires spécifiques Dans le Rhabdomyosarcome de l'Enfant, de l'Adolescent et du Jeune Adulte, Par Analyse Spatiale du protéome Par spectrométrie de Masse","AERO-RMS","Inclusion Criteria:\n\n* Age between 0 and 25 years at the time of initial diagnosis\n* Diagnosis of rhabdomyosarcoma confirmed histologically\n* Care at the Oscar Lambret Center between January 2005 and November 2024\n* No objection to the re-use of data and biological samples collected as part of care for research activities.\n\nExclusion Criteria:\n\n* Unavailability of biological sample in FFPE from biopsy and\u002For surgical specimen for diagnosis at Centre Oscar Lambret;\n* Patient under guardianship or trusteeship.","0 Years","25 Years",{"count":118,"type":21},20,"This non-interventional study aims to develop spatial proteomics for analyzing small FFPE tumor samples in rhabdomyosarcoma. It will identify molecular signatures linked to tumor regions, subtypes, survival, and treatment resistance, using pre-existing samples and data.",[121],"Rhabdomyosarcoma",[123,124,125,126],"rhabdomyosarcoma","molecular signatures","spatial proteome","targeted therapy","2025-04-04",{"date":129,"type":32},"2025-04-11",{"date":131,"type":32},"2025-03-13",{"date":133,"type":21},"2026-02-28",{"name":38,"class":39},{"id":136,"slug":137,"hasResults":11,"nctId":138,"briefTitle":139,"officialTitle":140,"acronym":141,"eligibilityCriteria":142,"healthyVolunteers":81,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":143,"targetDuration":4,"studyType":53,"phases":145,"briefSummary":146,"conditions":147,"keywords":149,"overallStatus":153,"whyStopped":4,"lastUpdateSubmitDate":154,"lastUpdatePostDateStruct":155,"startDateStruct":157,"completionDateStruct":159,"leadSponsor":161,"locationsCount":4},"100580085","fitness-and-well-being-of-caregivers-in-the-hauts-de-france-region-100580085","NCT06832709","Fitness and Well-being of Caregivers in the Hauts-de-France Region","Etat Des Lieux De La Santé Physique, Sociale Et Psychologique Des Aidants Dans Le Cadre Des Maladies Respiratoires Chroniques","PRHCARER","Inclusion Criteria:\n\n* Be of legal age;\n* Have a sick relative taking part in a RR program, either as an outpatient at the Clinique de la Mitterie or at home with FormAction Santé;\n* Have the cognitive ability to understand the instructions for carrying out the physical tests and the questions for answering the questionnaires;\n* Be able to read;\n* Have no disability preventing them from carrying out the physical tests;\n* Have given their written consent to take part in the research;\n* Be willing to comply with all the research procedures and duration.\n\nExclusion Criteria:\n\n* Refusal to sign consent;\n* Operation less than one month old;\n* Presence of psychological or psychiatric disorders;\n* Impossibility of receiving informed information;\n* Impossibility of participating in the entire study;\n* Contraindication to physical activity.",{"count":144,"type":21},54,[55],"The ageing of the population is accompanied by an increase in the frequency of chronic illnesses, leading to a rise in the number of caregivers. These caregivers do not have the time to look after their own health, and they are very often in a deteriorated mental state with no knowledge of their level of fitness. A deterioration in their fitness can be a source of the development of diseases induced by a sedentary lifestyle. On the other hand, patients with chronic respiratory disease can benefit from respiratory rehabilitation (RR), which includes outpatient or home-based physical activity. The literature has demonstrated an improvement in the mental state of caregivers following a RR carried out by their loved ones without taking an interest in their fitness. The aim of the study will be to establish 1. a representation of the level of fitness and mental state of caregivers; 2. to assess the presence\u002Fabsence of benefits on fitness and mental state of caregivers depending on the form of RR: home versus outpatient where the caregiver is not integrated in this last form.",[148],"Healthy",[95,150,151,152],"fitness","mental health","chronic respiratory disease","NOT_YET_RECRUITING","2025-02-25",{"date":156,"type":32},"2025-02-26",{"date":158,"type":21},"2025-03-15",{"date":160,"type":21},"2029-11-30",{"name":38,"class":39},{"id":163,"slug":164,"hasResults":11,"nctId":165,"briefTitle":166,"officialTitle":167,"acronym":168,"eligibilityCriteria":169,"healthyVolunteers":81,"sex":17,"minAge":18,"maxAge":170,"enrollmentInfo":171,"targetDuration":4,"studyType":53,"phases":173,"briefSummary":174,"conditions":175,"keywords":176,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":180,"lastUpdatePostDateStruct":181,"startDateStruct":182,"completionDateStruct":184,"leadSponsor":186,"locationsCount":72},"100572966","genetic-determinants-of-exercise-induced-muscle-damage-polygendomus-100572966","NCT06740136","Genetic Determinants of Exercise-Induced Muscle Damage (POLYGENDOMUS)","Genetic Determinants of Exercise-Induced Muscle Damage (POLYGENDOMUS) \u002F Déterminants Génétiques Des Dommages Musculaires Induits Par L'exercice (POLYGENDOMUS)","POLYGENDOMUS","Inclusion Criteria:\n\n* Male or female\n* Aged between 18 and 35\n* Weighing more than 50 kg\n* Member of a sports club affiliated to an Olympic federation\n* Socially insured\n* Willing to comply with all study procedures and duration of the study\n\nExclusion Criteria:\n\n* Medical history contraindicating sporting activities\n* Current medical treatment\n* Not a member of a sports club affiliated to an Olympic federation\n* Administrative reasons: impossibility of receiving informed information, impossibility of participating in the entire study, absence of social security coverage, refusal to sign consent form.","35 Years",{"count":172,"type":21},300,[55],"The objective of this study is to evaluate the association between the evolution of plasma CPK levels and genetic polymorphisms, both before the muscle-damaging exercise and at three post-exercise time points. The investigators aim to include 300 participants in this research.",[148],[177,178,179],"Muscle damage","Single nucleotide polymorphism","exercise","2024-12-13",{"date":68,"type":32},{"date":183,"type":32},"2023-03-13",{"date":185,"type":21},"2025-12-19",{"name":38,"class":39},""]