[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Lindsay Maguire, MD\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":43},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":32,"startDateStruct":35,"completionDateStruct":37,"leadSponsor":39,"locationsCount":42},"100522693","phase-1-feasibility-and-safety-of-ketamine-for-suicidal-patients-in-the-emergency-department-100522693",false,"NCT06085937","Feasibility and Safety of Ketamine for Suicidal Patients in the Emergency Department","Feasibility and Safety of Single Dose Ketamine for Acutely Suicidal Patients in the Emergency Department","Inclusion Criteria:\n\n* Acutely Suicidality (\"yes\" answer to any of items 4 or 5 on C-SSRS \"Suicidal Ideation\" category)\n* Require inpatient stabilization for SI or actions based on clinical observation and interview\n* Are accepted for psychiatric stabilization at the University of Kansas Medical Center's Strawberry Hill campus\n* Have a Glasgow Coma Score (GCS) of 15\n* Age 18-65\n\nExclusion Criteria:\n\n* Current or past history of psychosis\n* Current or recent (past 4 weeks) symptoms of mania\u002Fhypomania as defined by Young Mania Rating Scale (YRMS) score of 12 or greater\n* History of ketamine use disorder\n* History of liver transplant\n* Pregnancy or breastfeeding\n* Imprisonment or inability to consent\n* Positive urine drug screen or serum alcohol level\n* Hypertension (SBP \\> 160 or DBP \\> 100 before administration of ketamine)\n* Hypotension (SBP \\\u003C 90)\n* Presence of acute medical condition requiring admission to medical service\n* Allergy, intolerance, or previous adverse reaction to ketamine\n* Patient has 8+ lifetime ketamine exposures\n* The treating physician determines that the patient is not a good candidate for the study (e.g. medical condition\u002Fprocedure, medication that would contradindicate ketamine treatment)","ALL","18 Years","65 Years",{"count":20,"type":21},50,"ESTIMATED","INTERVENTIONAL",[24],"PHASE1","There is currently no readily available pharmacologic intervention for suicidal ideation, a true psychiatric emergency, in the Emergency Department (ED). Investigators aim to trial low-dose, intravenous ketamine, a drug with well-established use in treatment-resistant depression, for patients who present to the ED with suicidal ideation.",[27,28,29],"Suicide","Suicidal Ideation","Depression","RECRUITING","2026-04-12",{"date":33,"type":34},"2026-04-15","ACTUAL",{"date":36,"type":34},"2024-05-01",{"date":38,"type":21},"2027-04",{"name":40,"class":41},"Lindsay Maguire, MD","OTHER",2,""]