[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Linnaeus University\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":234},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,8,0,[8,41,83,117,144,171,194,214],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":17,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":29,"lastUpdatePostDateStruct":30,"startDateStruct":33,"completionDateStruct":35,"leadSponsor":37,"locationsCount":40},"100619929","exercise-as-medicine-a-non-pharmacological-approach-to-menopausal-symptoms-100619929",false,"NCT07351006","Exercise as Medicine: A Non-Pharmacological Approach to Menopausal Symptoms","Inclusion Criteria:\n\n* Biological female sex\n* Age 45-55 years\n* Experiencing menopausal symptoms, defined as irregular or altered menstruation plus at least one of the following:\n* Hot flashes or sweating\n* Sleep problems\n* Mood swings or depression\n* Dry mucous membranes\n* Recurrent urinary tract infections or overactive bladder\n* Joint pain\n* Decreased libido\n* Weight gain\n\nExclusion Criteria:\n\n* Have taken medication or natural remedies for menopausal symptoms in the past 2 months\n* Menopause due to illness or surgical intervention\n* Medical conditions that contraindicate participation in the exercise intervention\n* Engaged in physical activity for ≥150 minutes per week, including ≥ 75 minutes at high intensity","FEMALE","45 Years","55 Years",{"count":19,"type":20},45,"ESTIMATED","INTERVENTIONAL",[23],"NA","The aim of this clinical trial is to evaluate the effects of different forms of physical exercise in women experiencing menopausal symptoms. Specifically, the project investigates the effects of: (1) strength training on women's perceived menopausal symptoms; (2) dance-based exercise on women's perceived menopausal symptoms; and (3) adherence to structured, digital home-based exercise programs.\n\nThe following research questions will be addressed within the framework of the project:\n\nDoes regular strength training reduce women's perceived menopausal symptoms?\n\nTo what extent does strength training influence menopausal symptoms and sleep quality in women?\n\nWhat is the level of adherence to a digital, home-based strength training program among women with menopausal symptoms?\n\nDoes regular dance-based physical activity reduce women's perceived menopausal symptoms?\n\nTo what extent does dance-based physical activity influence menopausal symptoms and sleep quality in women?\n\nWhat is the level of adherence to a digital, home-based dance exercise program among women with menopausal symptoms?\n\nWhich exercise protocol-strength training or dance-based exercise-has the greatest effect on perceived menopausal symptoms?\n\nThe researchers will compare a digital, home-based strength training program with a digital, home-based dance exercise program, as well as with a control group, to determine which type of exercise has the greatest effect on menopausal symptoms and sleep quality.\n\nParticipants will:\n\nPerform either dance-based exercise or strength training for 8 weeks, three times per week, following a structured program of approximately 30 minutes per session, or participate as part of the control group.\n\nComplete validated questionnaires assessing menopausal health, including somatic, psychological, and sexual symptoms, as well as perceived quality of life and sleep quality, both before and after the intervention.\n\nMaintain a training diary to monitor adherence and progression, including increases in training intensity",[26,27],"Menopause Syndrome","Sleep Disturbance","RECRUITING","2026-01-09",{"date":31,"type":32},"2026-01-20","ACTUAL",{"date":34,"type":32},"2025-11-01",{"date":36,"type":20},"2026-12",{"name":38,"class":39},"Linnaeus University","OTHER",1,{"id":42,"slug":43,"hasResults":11,"nctId":44,"briefTitle":45,"officialTitle":46,"acronym":4,"eligibilityCriteria":47,"healthyVolunteers":11,"sex":48,"minAge":49,"maxAge":50,"enrollmentInfo":51,"targetDuration":4,"studyType":21,"phases":53,"briefSummary":54,"conditions":55,"keywords":60,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":78,"completionDateStruct":80,"leadSponsor":82,"locationsCount":40},"100470573","a-cluster-randomized-control-trial-of-pax-good-behavior-game-in-swedish-elementary-schools-100470573","NCT05407623","A Cluster-randomized Control Trial of PAX Good Behavior Game in Swedish Elementary Schools","PAX Good Behavior Game - A Cluster-randomized Controlled Evaluation and Qualitative Analysis of Effects on Work Environment, Learning, Mental Health and Health Economic Aspects of Implementing a Classroom-based Intervention","ON SCHOOL LEVEL:\n\nInclusion Criteria:\n\n* The school uses the general study plan (i.e. the school is not only working with students with special needs)\n* There is at least one teacher that is willing to participate, signs the study consent, and will be able to start the implementation in his\u002Fher class at the earliest in the second semester in the first grade or at the latest the first semester in the third grade.\n* The principal has signed an agreement to participate in the project, to allow some time for measurements to be administrated, aid in delivering information to the parents, and that the school are responsible for implementing the methods within their regular operation (given that supervision is provided by the research team)\n\nExclusion Criteria:\n\n* Another method that specifically aims to improve study and classroom environment is being implemented\n* Another method that is expected to be time and energy consuming for teachers is being implemented during the same period\n\nON TEACHER LEVEL:\n\nInclusion criteria:\n\n* The teacher mentors a class of 1st or 2nd graders following the general study plan (ready to implement the program no later than the first semester of the 3rd grade) and deems the class suitable for inclusion in the study\n* The teacher has signed the informed consent\n\nExclusion criteria:\n\n* The teacher has expressed plans to terminate their employment during the upcoming two years\n* A major change in the composition of the class is planned during the upcoming year.","ALL","6 Years","10 Years",{"count":52,"type":20},2184,[23],"Two important challenges that primary school in Sweden is confronted by are increasing levels of mental illness among children and adolescents and increasing rates of stress related symptoms and sick leave associated with mental illness in primary school teachers. Primary school is an important arena to address these issues.\n\nPAX is implemented as a part of the regular classroom activities and gives the teacher tools to promote behaviors that are constructive and learning oriented. The programme has been shown to improve student health and performance both short- and long-term. The teachers also receive tools to lessen stressors in their working environment. A Swedish uncontrolled pilot study showed increased well-being in children and reduced teacher stress as well as improved work related well-being at post-intervention.\n\nThe aim of this project is to study the effects of PAX on student well-being and teacher stress. In a cluster-randomized design, 84 teachers from 28 schools (clusters) will be randomized to either implement PAX, or to an active control group that receives the same amount of support but with different content. The PAX group will get a two-day education in PAX at the start of the term, followed by an implementation-term. The measurements include self-assessment, blind observer assessments, objectively measuring sound levels, data on sick leave and qualitative interviews.\n\nBaseline measurements are performed before implementation and primary end point is one year after. Costs and savings related to PAX will be measured and put in relation to the quality-adjusted life years of students and teachers. Long-term effects on student performance, health and participation in society will be evaluated in a follow-up project.",[56,57,58,59],"Well-being in Elementary School Children","Mental Health in Elementary School Children","Work-related Stress in Teachers","Academic Performance in Elementary School Children",[61,62,63,64,65,66,67,68,69,70,71,72,73,74],"Prevention","Pedagogy","Psychology","Leadership","Pedagogical leadership","Learning","Work-related stress","Mental health","Work environment","School-based research","Qualitative reserach","Quantitative research","Good classroom environment","Math skills","2025-04-08",{"date":77,"type":32},"2025-04-11",{"date":79,"type":32},"2021-04-21",{"date":81,"type":20},"2027-06-15",{"name":38,"class":39},{"id":84,"slug":85,"hasResults":11,"nctId":86,"briefTitle":87,"officialTitle":88,"acronym":89,"eligibilityCriteria":90,"healthyVolunteers":11,"sex":48,"minAge":91,"maxAge":4,"enrollmentInfo":92,"targetDuration":4,"studyType":21,"phases":94,"briefSummary":95,"conditions":96,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":110,"startDateStruct":111,"completionDateStruct":113,"leadSponsor":115,"locationsCount":116},"100431588","evaluation-of-primary-care-behavioral-health-pcbh-with-the-addition-of-self-help-cbt---a-randomized-multicenter-trial-100431588","NCT04900064","Evaluation of Primary Care Behavioral Health (PCBH) With the Addition of Self-help CBT - A Randomized Multicenter Trial","Evaluation of Primary Care Behavioral Health (PCBH) With the Addition of Self-help CBT - A Randomized Multicenter Trial for Superiority and Non-superiority Comparisons of Effects on Patients' Everyday Function, Symptoms, and Experiences","KAIROS","Inclusion Criteria:\n\n* All patients from age 18 who seek care at the PCC, who are deemed to be suitable for Behavioural Health interventions and booked to the mental health professionals at the PCC, according to screening methods and\u002For clinical assessments made by health care personnel at the PCC, will be included. This broad criteria reflects the naturalistic setting where decisions of clinicians, rather than highly standardized criteria, are the basis for inclusion.\n\nExclusion Criteria:\n\n* Does not speak Swedish well enough to fill out questionnaires or to receive self-help CBT in Swedish.\n* Is in need of emergency type care, like with suicidal ideation or behaviours, ongoing psychosis or mania.","18 Years",{"count":93,"type":20},1242,[23],"In this multicenter study, the investigators want to find out if an addition of an diagnostic assessment and possibility of treatment with guided self-help CBT can increase the treatment effects of PCBH on patient functioning and symptoms, compared to standard PCBH which uses contextual assessment and brief interventions. In addition to this, the study will investigate the overall effect of PCBH on both patient and organisation level outcomes.",[97,98,99,100,101,102,103,104,105,106,107,108,109],"Panic Disorder","Social Anxiety Disorder","Depression","Hypochondriasis","Insomnia","Generalized Anxiety Disorder","Burnout","Adjustment Disorders","Stress, Psychological","Obsessive-Compulsive Disorder","Life Stress","Life Style Induced Illness","Psychological Distress",{"date":77,"type":32},{"date":112,"type":32},"2021-06-14",{"date":114,"type":20},"2026-12-31",{"name":38,"class":39},4,{"id":118,"slug":119,"hasResults":11,"nctId":120,"briefTitle":121,"officialTitle":122,"acronym":123,"eligibilityCriteria":124,"healthyVolunteers":125,"sex":48,"minAge":126,"maxAge":4,"enrollmentInfo":127,"targetDuration":4,"studyType":21,"phases":129,"briefSummary":130,"conditions":131,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":136,"lastUpdatePostDateStruct":137,"startDateStruct":139,"completionDateStruct":141,"leadSponsor":143,"locationsCount":40},"100416301","a-randomized-controlled-evaluation-of-a-compassion-course-for-healthcare-professionals-100416301","NCT04700878","A Randomized Controlled Evaluation of a Compassion-course for Healthcare Professionals","A Randomized Controlled Evaluation of a Compassion-course With the Aim of Reducing Stress of Conscience and Work-related Stress and Increase Levels of Professional Quality of Life and Self-compassion in Healthcare Professionals","ICOP","Inclusion Criteria:\n\nThe inclusion criteria will be as follows: the participants work directly with patients full-time or part-time, score 45 points or higher on the primary outcome measure Stress of Conscience Questionnaire (SCQ), are proficient in Swedish, have the requisite time to attend a digital course, and accept the course's format.\n\nThe exclusion criteria include being partially or fully on sick leave due to stress.\n\nAll criteria are assessed on the basis of self-assessment forms of the participants, but in case of uncertainty, follow-up questions can be done by phone.",true,"20 Years",{"count":128,"type":20},548,[23],"The aim is to investigate whether an internet-based compassion course of five modules contributes to reducing stress of conscience and work-related stress, increase the experience of professional quality of life and self-compassion in healthcare professionals.",[132,133,134,135],"Psychological Stress","Compassion","Occupational Health","Cognitive Behavioral Therapy","2025-03-14",{"date":138,"type":32},"2025-03-19",{"date":140,"type":32},"2021-02-01",{"date":142,"type":20},"2027-12-31",{"name":38,"class":39},{"id":145,"slug":146,"hasResults":11,"nctId":147,"briefTitle":148,"officialTitle":148,"acronym":4,"eligibilityCriteria":149,"healthyVolunteers":11,"sex":48,"minAge":150,"maxAge":4,"enrollmentInfo":151,"targetDuration":4,"studyType":21,"phases":153,"briefSummary":154,"conditions":155,"keywords":158,"overallStatus":162,"whyStopped":4,"lastUpdateSubmitDate":163,"lastUpdatePostDateStruct":164,"startDateStruct":166,"completionDateStruct":168,"leadSponsor":170,"locationsCount":4},"100581507","do-emotions-and-pain-combined-affect-mechanical-pain-thresholds-and-other-pain-related-variables-in-individuals-with-chronic-pain-100581507","NCT06851208","Do Emotions and Pain Combined Affect Mechanical Pain Thresholds and Other Pain-related Variables in Individuals with Chronic Pain?","Inclusion Criteria:\n\n* Above 18 years of age\n* Fluent in Swedish\n* Persistent chronic pain with duration \\> 6 months\n\nExclusion criteria:\n\n\\- Known neurological disease","19 Years",{"count":152,"type":20},180,[23],"The purpose of this study is to investigate if different emotional states could influence mechanical pain thresholds and other pain - related variables such as pain tolerance, pain intensity and pain - related negative affect in individuals with chronic pain.",[156,157],"Pain Thresholds","Pain Intensity",[159,160,161],"Pressure pain thresholds","Pain","Emotions","NOT_YET_RECRUITING","2025-02-26",{"date":165,"type":32},"2025-02-28",{"date":167,"type":20},"2026-03-01",{"date":169,"type":20},"2026-06-30",{"name":38,"class":39},{"id":172,"slug":173,"hasResults":11,"nctId":174,"briefTitle":175,"officialTitle":176,"acronym":4,"eligibilityCriteria":177,"healthyVolunteers":11,"sex":48,"minAge":150,"maxAge":4,"enrollmentInfo":178,"targetDuration":4,"studyType":21,"phases":180,"briefSummary":181,"conditions":182,"keywords":184,"overallStatus":162,"whyStopped":4,"lastUpdateSubmitDate":187,"lastUpdatePostDateStruct":188,"startDateStruct":190,"completionDateStruct":192,"leadSponsor":193,"locationsCount":4},"100580353","do-emotions-affect-mechanical-pain-thresholds-in-individuals-with-chronic-pain-100580353","NCT06836193","Do Emotions Affect Mechanical Pain Thresholds in Individuals with Chronic Pain?","Do Emotions and Pain Combined Affect Mechanical Pain Thresholds and Other Pain-related Variables in Individuals with Chronic Pain","Inclusion criteria\n\n* Above 18 years of age\n* Fluent in Swedish\n* Persistent chronic pain with duration \\> 6 months Exclusion criteria\n* Known neurological disease",{"count":179,"type":20},152,[23],"The purpose of this study is to investigate if different emotional states could influence mechanical pain thresholds in individuals with chronic pain.",[183],"PRESSURE PAIN THRESHOLD",[185,160,186],"Pressure Pain Threshold","Emotion","2025-02-17",{"date":189,"type":32},"2025-02-20",{"date":191,"type":20},"2026-01-01",{"date":142,"type":20},{"name":38,"class":39},{"id":195,"slug":196,"hasResults":11,"nctId":197,"briefTitle":198,"officialTitle":198,"acronym":4,"eligibilityCriteria":199,"healthyVolunteers":11,"sex":48,"minAge":200,"maxAge":91,"enrollmentInfo":201,"targetDuration":4,"studyType":21,"phases":203,"briefSummary":204,"conditions":205,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":207,"lastUpdatePostDateStruct":208,"startDateStruct":210,"completionDateStruct":212,"leadSponsor":213,"locationsCount":40},"100483509","interpersonal-psychotherapy-for-adolescents-and-young-adults-100483509","NCT05575960","Interpersonal Psychotherapy for Adolescents and Young Adults","Inclusion Criteria:\n\n* Major depressive disorder according to the DSM-V\n* Age 15 to 17,5 years.\n* Good-enough knowledge in Swedish to be able to read instructions in questionnaires and who do not require an interpreter.\n\nExclusion Criteria:\n\n* Ongoing psychosis\n* Drug or alcohol addiction\n* Bipolar disorder\n* Suspected mental retardation\n* Acute suicidality or severe depression requiring hospitalization\n* Patients who have started antidepressant medication within the last six weeks will need to wait until medication effects have stabilized.","15 Years",{"count":202,"type":20},60,[23],"The purpose of the project is to study the effectiveness of Interpersonal Psychotherapy (IPT) for adolescents with depression. Specific aims are to analyze the effects, change mechanisms, predictors, and implementation of IPT for youth. In this four-year project we will include 60 patients with depression. Outcome will be studied using a quasi-experimental multiple-baseline design. Change mechanisms will be studied in the form of mentalizing, emotion regulation, social support, and working alliance session-by-session, and with post-treatment qualitative interviews about the participants' experiences of change. Predictors of effectiveness of IPT for adolescents will be explored by measuring severity of symptoms, anxiety symptoms, presence and severity of parent-child conflicts, quality of interpersonal relationships, experiences of bullying, and school functioning. The implementation process of IPT for youth will be studied through interviews with adolescents, parents, therapists, co-workers, and local managers.\n\nThe study is conducted within child and adolescent psychiatric services in Norrköping using a practice-oriented research strategy which emphasizes close collaboration with clinicians. The project is a collaboration between researchers at Linnaeus University and Linköping University, and clinicians at BUP Norrköping.",[206],"Major Depression","2024-05-17",{"date":209,"type":32},"2024-05-20",{"date":211,"type":32},"2022-10-03",{"date":81,"type":20},{"name":38,"class":39},{"id":215,"slug":216,"hasResults":11,"nctId":217,"briefTitle":218,"officialTitle":218,"acronym":4,"eligibilityCriteria":219,"healthyVolunteers":11,"sex":48,"minAge":4,"maxAge":4,"enrollmentInfo":220,"targetDuration":4,"studyType":21,"phases":222,"briefSummary":223,"conditions":224,"keywords":4,"overallStatus":162,"whyStopped":4,"lastUpdateSubmitDate":226,"lastUpdatePostDateStruct":227,"startDateStruct":229,"completionDateStruct":231,"leadSponsor":233,"locationsCount":40},"100540530","operation-acl-rehabilitation-after-anterior-cruciate-ligament-reconstruction-100540530","NCT06318039","Operation ACL: Rehabilitation After Anterior Cruciate Ligament Reconstruction","Inclusion Criteria:\n\n* Athletes or recreational athletes that have undergone ACLR\n\nExclusion Criteria:\n\n* Patients that have undergone ACLR that are nor athletes or recreational athletes",{"count":221,"type":20},100,[23],"Scientific Research Question\n\nOverall Purpose:\n\nRegarding rehabilitation after anterior cruciate ligament reconstruction (ACLR), there is a knowledge gap - a lack of evidence. Important questions such as how rehabilitation should be structured, what it should include, and how it should be evaluated are currently not clear. Therefore, the investigators plan to conduct a two-year follow-up randomized controlled trial (RCT) on post-ACLR rehabilitation.\n\nMoreover, detailed information on how\u002Funder what circumstances the ACL injury occurred is not satisfactorily described in the literature. Therefore, the investigators are planning a new survey that can identify, explain, and prevent the risk factors causing a person to suffer from an anterior cruciate ligament injury.\n\nSpecific Objectives:\n\nHow should guidelines for rehabilitation after ACLR be structured, what should they include, and how should they be evaluated to best restore knee function in the patient? Can a detailed and comprehensive survey identify, explain, and prevent the risk factors causing a person to suffer from an ACL injury?",[225],"Anterior Cruciate Ligament Reconstruction","2024-04-05",{"date":228,"type":32},"2024-04-08",{"date":230,"type":20},"2024-10-01",{"date":232,"type":20},"2027-10-01",{"name":38,"class":39},""]