[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Lishu Gao\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":45},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":29,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":4},"100623131","electroacupuncture-for-generalized-anxiety-disorder-clinical-efficacy-and-neuroimaging-mechanisms-100623131",false,"NCT07392645","Electroacupuncture for Generalized Anxiety Disorder: Clinical Efficacy and Neuroimaging Mechanisms","Clinical Efficacy of Electroacupuncture for Generalized Anxiety Disorder and Its Central Mechanism Based on Neuroimaging Changes","Inclusion Criteria:\n\n* Meet the DSM-5 diagnostic criteria for Generalized Anxiety Disorder (GAD).\n* No antidepressant or anti-anxiety medication in the past 2 weeks.\n* HAMA score ≥ 14.\n* Right-handed（for MRI).\n* Aged 18-60 years, with at least primary school education.\n* Signed informed consent.\n\nExclusion Criteria:\n\n* Complicated with severe cardiovascular, cerebrovascular, or organic diseases.\n* History of other psychiatric disorders (e.g., schizophrenia, bipolar disorder).\n* Contraindications for MRI (e.g., metal implants, claustrophobia).\n* Pregnancy or lactation.",true,"ALL","18 Years","60 Years",{"count":21,"type":22},123,"ESTIMATED","INTERVENTIONAL",[25],"NA","This study aims to evaluate the clinical efficacy and safety of electroacupuncture (EA) in treating Generalized Anxiety Disorder (GAD). Participants will be randomly assigned to an EA group, a sham EA group, or a waiting-list control group. All participants will continue their routine medication (Paroxetine). The primary goal is to observe the reduction in anxiety symptoms using the Hamilton Anxiety Scale (HAMA). Additionally, the study will use functional MRI (fMRI) and Magnetic Resonance Spectroscopy (MRS) to explore the brain mechanisms through which EA helps alleviate anxiety.",[28],"Generalized Anxiety Disorder",[30,28,31,32],"Electroacupuncture","fMRI","Clinical Efficacy","NOT_YET_RECRUITING","2026-02-05",{"date":36,"type":37},"2026-02-06","ACTUAL",{"date":39,"type":22},"2026-02-01",{"date":41,"type":22},"2027-12-31",{"name":43,"class":44},"Lishu Gao","OTHER",""]