[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Liyuan Hospital of Tongji Medical College, Huazhong University of Science and Technology\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":70},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,46],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":22,"studyType":23,"phases":4,"briefSummary":24,"conditions":25,"keywords":29,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":45},"100486901","durg-coated-balloon-angioplasty-in-infrapopliteal-lesions-100486901",false,"NCT05620095","Durg Coated Balloon Angioplasty in Infrapopliteal Lesions","Multicenter Registry for pAclitaxel- Coated Balloon angioplasTy in Infrapopliteal Arterial Lesions (the ACT Study)","Act","Inclusion Criteria:\n\n1. Rutherford grade 4-6.\n2. Patients who understand the purpose of this study, volunteer to participate in the experiment, sign informed consent and are willing to follow up.\n3. Single or sequential de novo or restenotic lesions (stenosis ≥ 70% diameter reduction or occlusion) in the infrapopliteal arteries \\>20 mm. Lesions should not extend beyond the ankle joint.\n4. Successful wire crossing of the lesion. After the pre-dilation of the ordinary balloon, the angiography showed that there was continuous blood flow.\n5. At least one of the infrapopliteal arteries received a drug-coated balloon.\n6. For patients with aortoiliac artery disease and femoral-popliteal artery disease, after intravascular reconstruction, blood flow can be recanalized, and there is no residual stenosis of more than 50%.\n7. In patients with lower extremity arterial thrombosis, after mechanical thrombectomy, percutaneous catheter thrombolysis, and thrombus removal, patients receiving blew the knee arterial drug balloon intervention.\n8. Patients who have received DCB intervention for both lower limbs can be enrolled in the group according to the intracavitary treatment time.\n9. Life expectancy\\> 24 months.\n\nExclusion Criteria:\n\n1. Blood flow was not successfully reestablished.\n2. Patients with stroke, cerebral hemorrhage, gastrointestinal hemorrhage or myocardial infarction within 3 months before enrollment.\n3. Patients who are known to be allergic to heparin, aspirin, other antiplatelet drugs, contrast agents, etc.\n4. Patients who have participated in clinical trials of drugs or other medical devices that interfere with this clinical trial within the past 3 months.\n5. Pregnant and lactating women.\n6. Patients with Berg's disease.\n7. Patients requiring major amputation based on preoperative evaluation of limb infection or severe ischemia","ALL","18 Years",{"count":20,"type":21},1000,"ESTIMATED","1 Year","OBSERVATIONAL","This study is a multicenter observational study designed to evaluate the the effectiveness and safety of drug-coated balloon (DCB) angioplasty for below the knee arterial lesions in patients critical with Limb Threatening Ischemia (CLTI).",[26,27,28],"Arteriosclerosis","Peripheral Artery Disease","Chronic Limb Threatening Ischemia",[30,31,32],"Drug-coated Balloon","Angioplasty","Below the knee","RECRUITING","2026-03-20",{"date":36,"type":37},"2026-03-25","ACTUAL",{"date":39,"type":37},"2020-12-01",{"date":41,"type":21},"2026-11-01",{"name":43,"class":44},"Liyuan Hospital of Tongji Medical College, Huazhong University of Science and Technology","OTHER",10,{"id":47,"slug":48,"hasResults":11,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":52,"eligibilityCriteria":53,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":54,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":56,"conditions":57,"keywords":59,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":61,"lastUpdatePostDateStruct":62,"startDateStruct":64,"completionDateStruct":66,"leadSponsor":68,"locationsCount":69},"100570946","angioplasty-with-shockwave-ivl-catheter-system-in-femoropopliteal-lesions-100570946","NCT06713850","Angioplasty With Shockwave IVL Catheter System in Femoropopliteal Lesions","Real-World Clinical Evaluation of the Shockwave Intravascular Lithotripsy (IVL) Catheter System for Treating Severe Calcified Lesions in Femoropopliteal Arteries","SHIELD","Inclusion Criteria:\n\n\\-\n\n1\\) Age ≥ 18 years (2) Rutherford Classification 2-5 3) Stenosis (\\>70% stenosis confirmed by digital subtraction angiography (DSA) imaging) or occlusion of the femoropopliteal artery, with one healthy patent outflow tract distal to the knee in continuity with a patent outflow tract below the ankle.\n\n(4) Patients who understand the purpose of the study, participate in the experiment voluntarily, sign the informed consent form and are willing to be followed up.\n\n5\\) The guidewire needs to pass through the lesion; 6) Life expectancy \\>24 months 7) Moderately severe calcified lesions confirmed by imaging data: 8) For patients who receive intervention in both lower extremities may be enrolled in order of time of intracavitary treatment 9) For combined aortoiliac artery lesions that have undergone endoluminal revascularization to achieve flow recanalization without more than 50% residual stenosis.\n\nExclusion Criteria:\n\n1. Patients with stroke, cerebral hemorrhage, gastrointestinal hemorrhage, or cardiac infarction within 3 months prior to enrollment (2) Patients with known allergy to heparin, aspirin, other antiplatelet drugs, contrast agents, etc.\n\n3\\) Patients who have been enrolled in medications that interfere with this clinical trial within the last 3 months or who have been treated intraoperatively with other special vascular bed preparation devices, such as plaque volume reduction devices, special balloons, and so on; 4) Pregnant and lactating women 5) Patients who are unable or unwilling to participate in this trial. 6) patients with Berger's disease 7) patients who have received arterial bypass diversion on the treated side",{"count":55,"type":21},130,"There is a lack of prospective observational studies of shockwave balloons in the treatment of moderate-to-severe calcification of the femoral popliteal artery at the international level. Therefore, in this study, we wish to set up a real-world study of shockwave balloon in the treatment of moderate-to-severe calcification to investigate the real-world efficacy of shockwave balloon in the treatment of moderate-to-severe calcified lesions.",[58,28],"Peripheral Artery Disease (PAD)",[27,28,60],"Severe calcification","2024-11-27",{"date":63,"type":37},"2024-12-03",{"date":65,"type":21},"2024-12-01",{"date":67,"type":21},"2028-11",{"name":43,"class":44},1,""]