[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Louis Bherer\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":50},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":30,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":39,"lastUpdatePostDateStruct":40,"startDateStruct":43,"completionDateStruct":45,"leadSponsor":47,"locationsCount":5},"100436347","a-combined-multidomain-intervention-to-prevent-cognitive-decline-associated-with-cardiovascular-risk-factors-100436347",false,"NCT04962061","A Combined Multidomain Intervention to Prevent Cognitive Decline Associated With Cardiovascular Risk Factors.","Impacts of Aerobic, Resistance and Cognitive Training Interventions on Neurocognitive Functions in Older Adults With Cardiovascular Risk Factors.","ACTIONcR","Inclusion Criteria:\n\n* Adult aged 60 and older,\n* Normal or corrected vision and normal hearing for their age range,\n* No cognitive impairment (Mini-Mental State Examination - MMSE ≥ 25),\n* Inactive (\\\u003C 150 min of physical activity per week).\n\nExclusion Criteria:\n\n* MMSE ≤ 24 or diagnosis of dementia,\n* Uncontrolled psychological \u002F psychiatric condition within the past 6 months,\n* Neurological disease,\n* Severe exercise intolerance,\n* Respiratory disease (e.g., asthma, COPD),\n* Excessive alcohol consumption (\\> 15 drinks\u002Fweek),\n* Documented cerebral, peripheral or coronary atherosclerotic disease,\n* Chronic systolic or diastolic heart failure,\n* Symptomatic aortic stenosis,\n* Atrial fibrillation,\n* Automatic implantable defibrillator or permanent pacemaker,\n* Malignant exertional arrhythmias,\n* Non-cardiopulmonary limitation to exercise (e.g., arthritis).",true,"ALL","60 Years",{"count":21,"type":22},159,"ESTIMATED","INTERVENTIONAL",[25],"NA","The ACTIONcardioRisk trial is designed to investigate the effect of aerobic and progressive resistance training exercises combined with cognitive training, on neurocognitive functioning of sedentary older adults with and without cardiovascular risk factors.",[28,29],"Aging","Cardiovascular Risk Factor",[28,31,32,33,34,35,36,37],"Cardiovascular Risk factor","Cognition","Combined Intervention","Cognitive Training","Physical Exercise","Brain Functions","Biomarkers","RECRUITING","2025-02-04",{"date":41,"type":42},"2025-02-06","ACTUAL",{"date":44,"type":42},"2021-09-01",{"date":46,"type":22},"2025-12-31",{"name":48,"class":49},"Louis Bherer","OTHER",""]