[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Lund University\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":709},{"pageToken":4,"total":5,"offset":6,"count":7,"results":8},null,27,0,25,[9,47,69,99,130,166,201,228,254,278,304,337,361,387,413,441,464,493,515,541,573,599,639,663,684],{"id":10,"slug":11,"hasResults":12,"nctId":13,"briefTitle":14,"officialTitle":15,"acronym":16,"eligibilityCriteria":17,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":20,"enrollmentInfo":21,"targetDuration":4,"studyType":24,"phases":25,"briefSummary":27,"conditions":28,"keywords":31,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100567625","intensive-dietary-and-activity-counselling-idac-100567625",false,"NCT06670625","Intensive Dietary and Activity Counselling (IDAC)","Intensive Dietary and Activity Counselling","IDAC","Inclusion Criteria:\n\n* The age of the infant at time of enrolment should be 3.0 months (13 - 17 weeks).\n* An increased genetic risk (7-10%) to develop beta-cell autoantibodies by the age of 6 years.\n\nGenetic inclusion criteria: Children without a T1D-FDR having HLA DR3\u002FDR4-DQ8, DR4-DQ8\u002FDR4-DQ8 or DR4-DQ8\u002FDR4-DQ7 rs6901541 C\u002FT genotype and:\n\n* for males having a genetic risk score greater than or equal to 18.2 but excluding those who are eligible for AVANT1A.\n* for females having a genetic risk score greater than or equal to 14.5 but excluding those who are eligible for AVANT1A.\n\nChildren with a T1D-FDR, all DR3\u002F3, DR4-DQ8\u002FDR4-DQ7 and DR4-DQ8\u002Fx where x is none of the following protective alleles: DRB1\\*1501, DQB1\\*0503, DRB1\\*1303 will be included regardless of genetic risk score.\n\n\\- Written informed consent signed by the custodial parent(s).\n\nExclusion Criteria:\n\n* Any medical condition, concomitant disease or treatment that may interfere with the assessments or may jeopardize the participant's safe participation in the study, as judged by the investigators.\n* Preterm delivery \\\u003C 36 weeks of gestation.\n* Any condition that could be associated with poor compliance.\n* Diagnosis of diabetes prior to recruitment or randomization.\n* Current use of any investigational drug.","ALL","3 Months","4 Months",{"count":22,"type":23},1244,"ESTIMATED","INTERVENTIONAL",[26],"NA","The aim of this intervention study is to investigate if a intensive dietary and physical activity counselling during the first two years of life in children with increased (genetically) risk for Type 1 Diabetes (T1D) can promote a healthy beta-cell environment, in order to reduce increased weight gain and development of islet autoimmunity (beta-cell autoantibodies).\n\nThe main hypotheses are:\n\n* Early lifestyle influences the susceptibility to islet autoimmunity (IA) by increasing beta-cell vulnerability. Introducing a \"healthy beta-cell lifestyle\" from infancy will reduce beta-cell vulnerability and the likelihood of IA.\n* Will promotion of a healthy beta-cell environment during early childhood in children with increased genetic risk of T1D reduce beta-cell stress, increased weight gain and development of islet autoantibodies?\n\nThe primary objective is to determine whether an Intensive Diet and Activity Counseling (IDAC) from age 3 months to age 2 years improves beta-cell health in children with increased risk for islet autoimmunity.\n\nSecondary objectives are to determine whether IDAC is associated with infant and early childhood growth and body composition and to determine whether IDAC reduces the cumulative incidence of islet autoantibodies or type 1 diabetes in childhood.\n\nParticipants will be randomized (ratio 1:1) to control group and intervention group. Breastfeeding status at time of randomization will be taken into account.\n\nParticipants will be enrolled by the age of four months and visit the research clinic ever third months up until the age of 24 months, and then yearly up until the age of 6 years.\n\n* Anthropometric measurements and blood draw will be taken at each visit.\n* Questionnaires focusing on breastfeeding and early infant feeding habits will be used at each visit.\n* 24hrs recalls will be done at the age of 6, 9, 12, 18 and 24 months of age.\n* Physical activity will be estimated using questionnaires (3, 6, 9 months) and accelerometer data (12, 18 and 24 months).\n* Stool samples will be collected at 6, 12 and 18 months of age",[29,30],"Type 1 Diabetes","Autoimmune Diabetes",[32,33],"islet autoimmunity","children","RECRUITING","2026-04-07",{"date":37,"type":38},"2026-04-13","ACTUAL",{"date":40,"type":38},"2025-03-15",{"date":42,"type":23},"2031-12-31",{"name":44,"class":45},"Lund University","OTHER",1,{"id":48,"slug":49,"hasResults":12,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":4,"eligibilityCriteria":53,"healthyVolunteers":12,"sex":18,"minAge":54,"maxAge":4,"enrollmentInfo":55,"targetDuration":4,"studyType":24,"phases":57,"briefSummary":58,"conditions":59,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":61,"lastUpdatePostDateStruct":62,"startDateStruct":64,"completionDateStruct":66,"leadSponsor":68,"locationsCount":46},"100596147","evaluation-viral-rna-and-virus-infectivity-in-exhaled-air-before-and-after-use-of-one-dose-with-coldzyme-mouth-spray-100596147","NCT07041671","Evaluation Viral RNA and Virus Infectivity in Exhaled Air Before and After Use of One Dose With ColdZyme Mouth Spray","Evaluation of Number of Particles Containing Viral RNA and Their Virus Infectivity in Exhaled Air From Participants With Upper Respiratory Tract Infection Symptoms, Before and After Use of One Dose With ColdZyme Mouth Spray","Inclusion criteria for subject selection:\n\n* Male and female subjects above age 18 (inclusive).\n* Presence of self-reported sudden onset of at least one of the following symptoms of upper respiratory tract infection case definitions for ILI and ARI (as defined by ECDC (EU 2008, 2012, 2022): Cough, sore throat, shortness of breath, non-allergic rhinitis, fever or feverishness, malaise, headache, myalgia.\n* Otherwise of general good health, according to Investigator's judgement.\n* Willing and able to give written informed consent for participation in the investigation.\n\nExclusion criteria for subject selection.\n\n* Known allergy or hypersensitivity to the components of ColdZyme.\n* Current use of immunosuppressive therapy within the last 4 weeks prior to Visit 1 and during the investigation.\n* Diagnosed chronic respiratory disease that could potentially impact the investigation results, according to Investigator's judgement.\n* Self-reported unhealed wounds\u002Fmucosal lesions in the mouth and\u002For throat.\n* Participation in another clinical study or investigation within 30 days prior to Visit 1.\n* Active smokers\n* The Investigator considers the subject unlikely to comply with investigational procedures, restrictions and requirements.","18 Years",{"count":56,"type":23},200,[26],"Many respiratory diseases spread through aerosols. ColdZyme is a mouth spray that protects against upper respiratory tract viruses causing common cold and flu-like symptoms. ColdZyme forms a protective moisturizing barrier on the mucous membrane of the oral cavity and throat. The objective of this study is assessing if ColdZyme could also contribute to decreased airborne transmission by decreasing the amount of (infectious) virus that is exhaled by an infected subject.",[60],"URTI - Viral Upper Respiratory Tract Infection","2026-03-31",{"date":63,"type":38},"2026-04-06",{"date":65,"type":38},"2025-06-30",{"date":67,"type":23},"2028-12",{"name":44,"class":45},{"id":70,"slug":71,"hasResults":12,"nctId":72,"briefTitle":73,"officialTitle":74,"acronym":75,"eligibilityCriteria":76,"healthyVolunteers":12,"sex":18,"minAge":54,"maxAge":77,"enrollmentInfo":78,"targetDuration":4,"studyType":24,"phases":80,"briefSummary":81,"conditions":82,"keywords":86,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":91,"lastUpdatePostDateStruct":92,"startDateStruct":94,"completionDateStruct":96,"leadSponsor":98,"locationsCount":46},"100504846","education-and-exercise-for-patients-with-longstanding-hip-and-groin-pain-100504846","NCT05853640","Education and Exercise for Patients With Longstanding Hip and Groin Pain","Patients With Longstanding HIP and Groin Pain Referred to Orthopedic Care: Effectiveness of Education and exerciSe ThERapy (HIPSTER)","HIPSTER","Inclusion Criteria:\n\n* Men and women aged 18-55 years\n* Referred to the Dept of Orthopedics due to hip and\u002For groin pain\n* Activity-related unilateral or bilateral groin pain \\>3 months\n* Pain reproduced with the FADIR test.\n\nExclusion Criteria:\n\n* Groin pain originating from any diagnosis with other treatment pathways, i.e., i) Acute traumatic hip injuries (such as hip dislocation, hip fractures); ii) Verified moderate or severe OA (Tönnis grade \\>1); iii) Palpable hernia; iv) Low-back pain with a positive straight leg raise test and\u002For hip and groin pain provoked primarily by repeated motions of the lumbar spine; v) Sacroiliac joint pain with thigh thrust test.\n* Co-morbidities potentially interfering with treatment, i.e., i) Co-morbidities overriding the hip and groin-related symptoms and dysfunction (such as other acute lower limb injuries, rheumatoid arthritis etc), ii) Co-morbidities prohibiting physical activity and training (heart disease etc), iii) Current psycho-social disorders requiring treatment.\n* Other: i) History of drug abuse within the last year; ii) Not understanding the language of interest (Scandinavian languages, or English).","55 Years",{"count":79,"type":23},122,[26],"Longstanding hip and groin pain (LHGP) is a common and debilitating problem in young to middle aged individuals. These patients often get referred to orthopedic departments. Consensus statements on the management of these patients commonly recommend a physical therapist-led intervention as the first line intervention. However, the optimal content and delivery of this intervention is currently unknown. In this study we will compare the effectiveness of usual care (unstructured physical therapist-led intervention) to a semi-structured, progressive individualized physical therapist-led intervention on hip-related quality of life in people with longstanding hip and groin pain referred to an orthopedic department.",[83,84,85],"Hip Pain Chronic","Femoro Acetabular Impingement","Groin Injury",[87,88,89,90],"Hip-related pain","Longstanding hip and groin pain","Exercise therapy","Rehabilitation","2026-03-26",{"date":93,"type":38},"2026-04-02",{"date":95,"type":38},"2023-07-24",{"date":97,"type":23},"2030-12",{"name":44,"class":45},{"id":100,"slug":101,"hasResults":12,"nctId":102,"briefTitle":103,"officialTitle":104,"acronym":4,"eligibilityCriteria":105,"healthyVolunteers":12,"sex":18,"minAge":106,"maxAge":107,"enrollmentInfo":108,"targetDuration":4,"studyType":24,"phases":110,"briefSummary":111,"conditions":112,"keywords":116,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":121,"lastUpdatePostDateStruct":122,"startDateStruct":124,"completionDateStruct":126,"leadSponsor":128,"locationsCount":129},"100625691","digital-peer-support-based-anti-hiv-stigma-intervention-among-adolescents-living-with-hiv-in-ethiopia-100625691","NCT07425925","Digital Peer-support-based Anti-HIV Stigma Intervention Among Adolescents Living With HIV in Ethiopia","Feasibility and Effectiveness of Digital Peer-support-based Anti-HIV Stigma Intervention in Improving Clinical Outcomes Among Adolescents Living With HIV in Ethiopia","Inclusion Criteria:\n\n* Adolescents who have been disclosed of their HIV status\n* adolescents and young people between the age of 15 and 22 years old\n* receiving antiretroviral medications; and\n* completed at least first cycle primary school education (i.e. grade 4).\n\nExclusion Criteria:\n\n* Participants with known diagnosed mental health condition\n* Participants with hearing loss or loss of vision","14 Years","22 Years",{"count":109,"type":23},282,[26],"Advances in HIV care and treatment turned a once deadly disease into a chronic condition where people living with HIV, including perinatally HIV acquired children, can now lead a healthy life and live longer with their highly effective antiretroviral therapy. Despite the advancements and successes in HIV care and treatment, HIV-related stigma remained a challenge to people living with HIV and for the provision of the available successful treatment and support. Stigma and discrimination related to HIV infection inhibit health-seeking behaviour, clinical outcomes, physical and psychosocial wellbeing and is a major obstacle for timely diagnosis.\n\nPeer support programs to people living with HIV appeared to have improved self-confidence of members and consequently reduced self-stigma and improved their coping ability against external stigma. However, these services are limited in terms of geography owing to lack of adequate financing to cover operational costs for adolescents coming from rural areas and space and facility limitation to accommodate large groups.\n\nThe eHealth services have potential to provide some of the services offered in the in-person sessions of the peer support group. Despite this important potential of eHealth services, they are underutilized and are not often used to target HIV-related stigma in adolescents living with HIV. The present study will investigate whether the digital peer-support anti-HIV stigma reduces internalized and anticipated stigma among adolescents living with HIV (ALHIV) in South Ethiopia. Further, we will explore the health-related outcomes including adolescent's psychological wellbeing, retention in care and sustained viral load suppression.",[113,114,115],"HIV-related Stigma","Psychological Wellbeing","Retention in Care",[117,118,119,120],"digital peer-support","HIV-related stigma","adolescents living with HIV","south Ethiopia","2026-02-19",{"date":123,"type":38},"2026-02-23",{"date":125,"type":38},"2025-11-13",{"date":127,"type":23},"2026-05-01",{"name":44,"class":45},5,{"id":131,"slug":132,"hasResults":12,"nctId":133,"briefTitle":134,"officialTitle":135,"acronym":4,"eligibilityCriteria":136,"healthyVolunteers":12,"sex":18,"minAge":137,"maxAge":138,"enrollmentInfo":139,"targetDuration":4,"studyType":24,"phases":141,"briefSummary":142,"conditions":143,"keywords":151,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":121,"lastUpdatePostDateStruct":159,"startDateStruct":161,"completionDateStruct":163,"leadSponsor":165,"locationsCount":46},"100566921","internet-delivered-cognitive-behavioral-intervention-for-youths-with-anxiety-disorders-100566921","NCT06661460","Internet-Delivered Cognitive Behavioral Intervention for Youths With Anxiety Disorders","Development and Preliminary Evaluation of a New Internet-Delivered Cognitive Behavioral Intervention for Youths With Anxiety Disorders","Inclusion Criteria:\n\n1\\) 8 to \\\u003C18 years of age.\n\n* Confirmed by the child\u002Fcaregiver and subsequently by the medical record system. 2) A principal DSM-5-TR anxiety disorder of specific phobia, separation anxiety disorder, social anxiety disorder, generalized anxiety disorder, panic disorder or agoraphobia.\n* Confirmed by the Diagnostic Interview for Anxiety, Mood, and OCD and related Neuropsychiatric Disorders - Child and Adolescent Version (DIAMOND-KID).\n\n  3\\) Child and caregiver able to read, write and communicate in Swedish.\n* Confirmed by the child\u002Fcaregiver. 4) An available caregiver who can support the child in treatment.\n* Confirmed by the caregiver. 5) Access to a smartphone, tablet, or laptop\u002Fdesktop device, and the internet.\n* Confirmed by the child\u002Fcaregiver.\n\nExclusion Criteria:\n\n1\\) Principal DSM-5-TR anxiety disorder of specific phobia concerning the domain of blood-injection-injury (due to the ICBT program not including relevant information on applied-tension techniques to avoid fainting during exposure exercises).\n\n* Confirmed by a blood-injection-injury phobia being classified as the principal anxiety disorder as assessed by the DIAMOND-KID.\n\n  2\\) Established or suspected intellectual disability.\n* Confirmed by the caregiver (through previous diagnosis) and\u002For by attending a special needs school for learning difficulties.\n\n  3\\) Another mental disorder in more immediate need of management than an anxiety disorder (e.g., schizophrenia spectrum and other psychotic disorders, bipolar disorder, anorexia nervosa, substance use disorders).\n* According to the DIAMOND-KID and\u002For other available sources. 4) Social\u002Ffamilial\u002Feducational difficulties in more immediate need of management than an anxiety disorder.\n* Confirmed by the assessor through information from the child\u002Fcaregiver and\u002For other available sources.\n\n  5\\) Immediate risk to self or others that require urgent attention, such as acute suicidality.\n* Confirmed by the assessor through information from the child\u002Fcaregiver and other available sources.\n\n  6\\) Previous CBT for an anxiety disorder, defined as five or more sessions with a certified CBT therapist within the 12 months prior to assessment.\n* Confirmed by the child\u002Fcaregiver or the medical record system. 7) Ongoing psychological treatment for an anxiety disorder.\n* Confirmed by the child\u002Fcaregiver or the medical record system. 8) Initiation or adjustment of any psychotropic medication for anxiety (i.e., selective serotonin reuptake inhibitors, tricyclic antidepressants, serotonin-norepinephrine reuptake inhibitor or antipsychotics) within 8 weeks prior to assessment.\n* Confirmed by the child\u002Fcaregiver or the medical record system. 9) Participation in user involvement sessions in the present study.\n* Confirmed by the researcher.","8 Years","17 Years",{"count":140,"type":23},48,[26],"The goal of this study is to develop a new internet-delivered cognitive behavioral therapy (ICBT) intervention for youths with anxiety disorders based on the best current knowledge about effective cognitive behavioral therapy for the target group, refine the intervention in collaboration with patient and public representatives, and conduct a preliminary evaluation of the treatment effects in an open clinical trial.\n\nThe primary objective of the study is:\n\n1\\. To evaluate the preliminary efficacy of a newly developed ICBT intervention for children and adolescents with anxiety disorders in reducing anxiety severity, as measured by the Pediatric Anxiety Rating Scale (PARS).\n\nSecondary objectives of the study are:\n\n1. To examine the preliminary efficacy (PARS) of the ICBT intervention at 3 months post-treatment.\n2. To examine how youths with anxiety disorders, their caregivers, therapists, and healthcare leadership experience the ICBT intervention.\n3. To examine factors (e.g., age, type of anxiety disorder, presence of depressive symptoms, experiences of ICBT) that predict treatment outcome.\n4. To examine how the ICBT intervention can be improved (e.g., treatment content and technical delivery) for future use.\n\nParticipants will:\n\n* Undergo ICBT treatment for anxiety disorders during 12 weeks\n* Complete questionnaires at multiple time points throughout the study\n* Participate in follow-ups post-treatment and 3 months post-treatment\n* A selection of participants will also be invited to focus group interviews with the aim to generate ideas on how the intervention may be improved for future use",[144,145,146,147,148,149,150],"ANXIETY DISORDERS (or Anxiety and Phobic Neuroses)","Specific Phobia","Social Anxiety Disorder","Separation Anxiety Disorder","Generalized Anxiety Disorder","Panic Disorder","Agoraphobia",[152,153,154,155,156,157,158],"Anxiety disorders","Children","Adolescents","Cognitive Behavioral Therapy","Remote delivery","Internet","Internet-delivered cognitive behavioral therapy",{"date":160,"type":38},"2026-02-20",{"date":162,"type":38},"2025-12-12",{"date":164,"type":23},"2027-06-01",{"name":44,"class":45},{"id":167,"slug":168,"hasResults":12,"nctId":169,"briefTitle":170,"officialTitle":171,"acronym":172,"eligibilityCriteria":173,"healthyVolunteers":174,"sex":18,"minAge":175,"maxAge":4,"enrollmentInfo":176,"targetDuration":4,"studyType":24,"phases":178,"briefSummary":179,"conditions":180,"keywords":186,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":192,"lastUpdatePostDateStruct":193,"startDateStruct":195,"completionDateStruct":197,"leadSponsor":199,"locationsCount":200},"100568905","light-in-healthcare-environment-ljus-i-sjukhusmilj-100568905","NCT06687304","Light in Healthcare Environment (Ljus i sjukhusmiljö)","Benefits of Light in the Radiographic Environment","LIS","Inclusion Criteria:\n\nRadiographer\n\nExclusion Criteria:\n\n\\-",true,"21 Years",{"count":177,"type":23},18,[26],"The goal of this clinical trial is to learn if light can enhance the feeling of well-being and sleep quality in Radiographers. It will also find out if there is an optimal recipe for light. The main questions it aims to answer are:\n\n* Will alertness, energy levels, and sleep quality increase in radiographers when the lighting is differed?\n* What light recipe is the most beneficial for the personnel? Researchers will compare no enhanced light environment to different enhanced light environment to see if the enhanced light is beneficial for radiographers.\n\nParticipants will:\n\n* Will work in an enhanced light environment or a non-enhanced light environment\n* Answer surveys\n* Take saliva sample",[181,182,183,184,185],"Sleep Quality","Well-being","Melatonin","Cortisol","Energy Levels",[187,188,189,190,191],"Light","Radiography","Light environment","Circadian rhythm","Personnel at radiology departments","2025-11-24",{"date":194,"type":38},"2025-12-02",{"date":196,"type":38},"2024-11-15",{"date":198,"type":23},"2027-03-31",{"name":44,"class":45},3,{"id":202,"slug":203,"hasResults":12,"nctId":204,"briefTitle":205,"officialTitle":206,"acronym":207,"eligibilityCriteria":208,"healthyVolunteers":12,"sex":18,"minAge":54,"maxAge":4,"enrollmentInfo":209,"targetDuration":4,"studyType":24,"phases":211,"briefSummary":212,"conditions":213,"keywords":218,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":220,"lastUpdatePostDateStruct":221,"startDateStruct":223,"completionDateStruct":225,"leadSponsor":227,"locationsCount":46},"100609483","manual-lymph-drainage-for-external-lymphedema-100609483","NCT07215169","Manual Lymph Drainage for External Lymphedema","The Effect of Manual Lymph Drainage for Cancer Treatment-related External Lymphedema in the Head and Neck - a Pilot and Feasibility Study of a Randomized Controlled Trial","MLD-HN","Inclusion Criteria:\n\n* • a previous diagnosis of oropharyngeal cancer (all histological types are accepted)\n\n  * curative treatment with (chemo)radiotherapy to at least 68Gy at the primary site completed no more than 1 year before the study inclusion\n  * age \\>18 years\n  * ability to give written and informed consent.\n\nExclusion Criteria:\n\n* • pregnancy\n\n  * surgery or Botox injections in the tissue of the head and neck area\n  * Locoregional deep infection i.e., suspected abscess at the scheduled time points for measurements.\n  * prior daily treatment with Self MLD\n  * other treatment of head and neck lymphedema, for example compression\n  * psychiatric disorders\n  * substance abuse problems",{"count":210,"type":23},40,[26],"This study will evaluate the feasibility of a randomized controlled trial. The future randomized controlled trial will compare two groups following different intensities of manual lymphatic drainage for external head- and neck lymphedema among persons treated with radiotherapy for head- and neck cancer.",[214,215,216,217],"Lymphedema of Face","Neoplasms","Radiotherapy Side Effect","Lymphedema Due to Radiation",[219],"Head and neck lymphedema management","2025-10-02",{"date":222,"type":38},"2025-10-10",{"date":224,"type":38},"2025-10-01",{"date":226,"type":23},"2027-06",{"name":44,"class":45},{"id":229,"slug":230,"hasResults":12,"nctId":231,"briefTitle":232,"officialTitle":233,"acronym":4,"eligibilityCriteria":234,"healthyVolunteers":12,"sex":18,"minAge":54,"maxAge":4,"enrollmentInfo":235,"targetDuration":4,"studyType":24,"phases":237,"briefSummary":238,"conditions":239,"keywords":243,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":247,"lastUpdatePostDateStruct":248,"startDateStruct":250,"completionDateStruct":252,"leadSponsor":253,"locationsCount":46},"100603791","self-monitoring-and-remote-monitoring-of-chronic-pain-in-primary-care---using-a-digital-tool-to-improve-quality-of-life-100603791","NCT07141108","Self-monitoring and Remote Monitoring of Chronic Pain in Primary Care - Using a Digital Tool to Improve Quality of Life","Egenmonitorering Och Distansmonitorering av långvarig smärta i primärvården, användandet av Ett Digitalt Verktyg för Att ökad livskvalité","Inclusion Criteria:\n\nHas pain that affects daily life and has lasted for more than 3 months\n\nIs over 18 years old\n\nUnderstands Swedish or English\n\nIs motivated and willing to use a digital tool for self-monitoring of activity level and symptoms\n\nHas no planned surgeries during the study period\n\nHas knowledge of and access to using a smartphone or tablet\n\nExclusion Criteria:\n\nSevere or acute mental illness, severe anxiety, or depression\n\nOngoing history of substance use disorder\n\nSerious illness under active treatment\n\nPain related to malignancy\n\nCurrently involved in legal proceedings or ongoing litigation related to low back or neck pain\n\n\\-",{"count":236,"type":23},30,[26],"Chronic pain impacts individuals, their families, and society significantly, yet specialist care resources are limited, with most patients managed in primary care. There is a need for tools that support self-management and improve resource allocation. This feasibility study evaluates the implementation of Paindrainer®, a CE-marked Class I digital tool, in primary care. Paindrainer® combines patient self-monitoring via an app with a healthcare provider portal (CARE) for remote monitoring. Using advanced neural networks, it offers personalized feedback to help patients plan and monitor daily activities and their impact on pain. The study aims to assess whether integrating this tool can enhance chronic pain management and patient quality of life.",[240,241,242],"Persistent Pain","Pain Management","Remote Monitoring",[244,245,246],"chronic pain","pain management","persistent pain","2025-08-18",{"date":249,"type":38},"2025-08-26",{"date":251,"type":38},"2025-05-14",{"date":61,"type":23},{"name":44,"class":45},{"id":255,"slug":256,"hasResults":12,"nctId":257,"briefTitle":258,"officialTitle":258,"acronym":4,"eligibilityCriteria":259,"healthyVolunteers":12,"sex":18,"minAge":54,"maxAge":4,"enrollmentInfo":260,"targetDuration":262,"studyType":263,"phases":4,"briefSummary":264,"conditions":265,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":270,"lastUpdatePostDateStruct":271,"startDateStruct":273,"completionDateStruct":275,"leadSponsor":277,"locationsCount":46},"100548708","effects-of-psychiatric-admissions-on-self-harm-and-suicide-in-people-with-borderline-personality-disorder-100548708","NCT06424509","Effects of Psychiatric Admissions on Self-harm and Suicide in People With Borderline Personality Disorder","Inclusion Criteria:\n\n* Psychiatric clinic in Sweden authorized to administer compulsory care for adults. Each clinic per specific calendar year will represent one participant, identified by the clinic's name and the respective year (e.g., Umeå2010, Linköping2013, Malmö2022).\n\nExclusion Criteria:\n\n* No authorization to administer compulsory care for adults",{"count":261,"type":23},390,"1 Year","OBSERVATIONAL","The current study aims to evaluate the impact of long (\\>5 days) and\u002For compulsory psychiatric inpatient care on subsequent healthcare utilization for self-harm and suicide in people with borderline personality disorder, a condition characterized by frequent self-harm.\n\nThe basis for this study is the diversity of clinical practices across Swedish regions. By categorizing clinics based on their practices with respect to long and\u002For compulsory psychiatric inpatient care, it is possible to explore the impact of these practices on subsequent somatic and psychiatric healthcare, including emergency care due to self-harm as well as on completed suicides.\n\nAll psychiatric clinics across Sweden authorized to administer compulsory care for adults, totalling 78 clinics will be included. Each clinic per specific calendar year will represent one participant, identified by the clinic's name and the respective year (e.g., Umeå2010, Linköping2013, Malmö2022).\n\nData collection will involve the utilization of the national registers to capture outcome measures and account for confounding factors. The participants will be ranked based on a composite variable, which includes the average number of days spent in inpatient compulsory care and other psychiatric inpatient care exceeding 5 days, among individuals diagnosed with BPD. The top quartile of participants will be compared with the bottom quartile.",[266,267,268,269],"Borderline Personality Disorder","Self-harm","Non-suicidal Self-injury","Suicide","2025-08-06",{"date":272,"type":38},"2025-08-12",{"date":274,"type":38},"2010-01-01",{"date":276,"type":23},"2027-01-01",{"name":44,"class":45},{"id":279,"slug":280,"hasResults":12,"nctId":281,"briefTitle":282,"officialTitle":282,"acronym":4,"eligibilityCriteria":283,"healthyVolunteers":174,"sex":18,"minAge":54,"maxAge":284,"enrollmentInfo":285,"targetDuration":4,"studyType":24,"phases":287,"briefSummary":288,"conditions":289,"keywords":291,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":297,"lastUpdatePostDateStruct":298,"startDateStruct":300,"completionDateStruct":302,"leadSponsor":303,"locationsCount":46},"100596548","analysis-of-the-gut-microbiota-composition-after-consumption-of-probiotic-bacteria-100596548","NCT07046897","Analysis of the Gut Microbiota Composition After Consumption of Probiotic Bacteria","Inclusion Criteria:\n\n• You must be 18-65 years of age.\n\nExclusion Criteria:\n\n* Participants must not be diagnosed with gastrointestinal diseases, autoimmune diseases or have diseases or medications that cause immune deficiency such as MS, type 1 diabetes, cancer or HIV.\n* Participants must not have taken antibiotics in the month before or during the study.\n* Participants must not consume other probiotic products or fermented foods during the study.","65 Years",{"count":286,"type":23},60,[26],"The goal of this intervention study is to evaluate the beneficial effect of the probiotic bacterium Bacillus coagulans in healthy volunteers. The main question it aims to answer is if the probiotic strains are modifying the microbiota composition in a beneficial way, evaluated in faecal- and saliva samples.\n\nPrimary hypothesis: The probiotic bacteria will modify the microbiota composition in faecal- and saliva samples.\n\nParticipants will consume the freeze-dried probiotic bacteria for 14 days. Before and after consumption, the participants will collect samples.",[290],"Microbiota Analysis in Healthy Subjects",[292,293,294,295,296],"Probiotics","Microbiota composition","Saliva","Faeces","Healthy individuals","2025-06-23",{"date":299,"type":38},"2025-07-02",{"date":301,"type":38},"2024-11-12",{"date":65,"type":23},{"name":44,"class":45},{"id":305,"slug":306,"hasResults":12,"nctId":307,"briefTitle":308,"officialTitle":309,"acronym":310,"eligibilityCriteria":311,"healthyVolunteers":174,"sex":18,"minAge":312,"maxAge":313,"enrollmentInfo":314,"targetDuration":4,"studyType":24,"phases":316,"briefSummary":317,"conditions":318,"keywords":321,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":329,"lastUpdatePostDateStruct":330,"startDateStruct":332,"completionDateStruct":334,"leadSponsor":336,"locationsCount":46},"100594918","exercise-training-among-children-with-cerebral-palsy-to-increase-health-and-well-being---a-feasibility-study-100594918","NCT07025694","Exercise Training Among Children With Cerebral Palsy to Increase Health and Well-being - A Feasibility Study","Feasibility Testing of a Homebased Exercise Intervention in Children With Cerebral Palsy Who Are Ambulant - The HOME-EX Study","HOME-EX","Inclusion Criteria:\n\n* children with CP-A defined as GMFCS-E\\&R I-II\n* children who are TD and not participating in any regular and planned leisure time physical exercise will be included in the study.\n\nExclusion Criteria:\n\n* Ambulant children with CP walking with a walking aid (GMFCS-E\\&R III);\n* ambulant children who are TD with other neurological diagnoses, metabolic diagnoses, orthopaedic disabilities, asthma, heart diseases, cognitive impairment, or indigestion of regular medication.","10 Years","16 Years",{"count":315,"type":23},20,[26],"The use of eHealth in children with cerebral palsy (CP) holds promise to increase participation in exercise. eHealth, has shown to increase accessibility to appropriate healthcare professionals as well as reduces time- and energy consuming transportation to\u002Ffrom physical appointments\\[5\\]. In children with CP reduced transportation to and from appointments, increased access to appropriate healthcare s professionals have shown to increase exercise.\n\nHowever, the knowledge on how eHealth can support children with CP to participate in exercise is scarce and to the best of our knowledge there are no studies studying eHealth to increase exercise in children with CP. If HOME-EX research project is successful, we will unravel knowledge that will facilitate implementation of prescription of targeted, personalized exercise regimes to children with CP to enhance health and wellbeing and furthermore set a healthy lifestyle.\n\nPURPOSE AND AIMS\n\nThe overall goal of the HOME-EX project is to develop, feasibility test, pilot the efficacy and map the conditions for future implement an eHealth application to support participation in exercise at home in children with CP who are ambulant (CP-A). The specific aims are:\n\nAim 1: From a pre-exciting eHealth-solution develop an application for Android-based tablet supporting exercise in the home of the children with CP-A in co-creation with children, family caregivers, professional caregivers, sports professionals and researchers.\n\nAim 2: Develop exercise sessions, as online supervised session and pre-video recorded sessions in co-creation with children, family caregivers, professional caregivers, sports professionals and researchers, to be delivered by the eHealth-solution.\n\nAim 3: To study the feasibility of the delivery of the exercise sessions from the eHealth-solution.\n\nPROJECT DESCRIPTION Cerebral palsy (CP) is the most common physical disability in childhood, approximately 1.6\u002F1000 children have CP with affected muscle tone, movement and motor skills, often accompanied by pain, epilepsy and intellectual, communicational and behavioural impairment.\n\nThe degree of motor impairment in CP is extremely variable and classified with the 5-level Gross Motor Function Classification System Expanded \\& Revised (GMFCS-E\\&R). Children with CP-A (GMFCS-E\\&R level I-II) can either walk and\u002F stand independently.\n\nProject management Since children are non-autonomous, the common point of departure for our research is the family; lifestyle changes as well as interventions must be implemented through the family. Feasibility testing aims to analyse clinical, procedural, and methodological uncertainties of the exercise testing and the exercise training interventions designed in co-creation with stakeholders. If no major changes are made to the study design and\u002For the intervention these children will be included into the piloting phase.\n\nRecruitment In total, 20 children - 10 children with CP-A and 10 who are TD as healthy controls - aged between 10 to 16 years old will be recruited. The children in the two groups will be matched for age, BMI, and physical activity level.\n\nStudy 1: Addressing aim 1-2 - Development of an exercise-application Methodology: Workshops to further develop the eHealth app: Four separate workshops will then be conducted to discuss the functions and the setup of communication of the initial prototype, as well as how to deliver the exercise sessions and what they preferably may contain. Workshop 1 will consist of 4-6 children children with CP-A and TD. Workshop 2 will consist of family caregivers. Workshop 3 of professional caregivers as physiotherapists and workshop 4 of sport professionals as personal trainers. The workshops will employ a participatory approach, enabling active contributions from participants and be facilitated by researchers from the research group. After the workshops, the eHealth app will be updated by a technician based on the feedback received.\n\nStudy 2: Addressing aim 3 - Feasibility testing of an exercise-application Methodology: Four children in each group, in total eight children, will take part in the feasibility analysis. During the first three weeks will the children be supervised at schedule timepoints through an eHealth solution and during the last three weeks the children follows pre-recorded exercise sessions at a suitable time for the family.\n\nAfter the first 6 weeks of exercise training procedural, clinical and methodological uncreates will be analysed. Feedback from the participants and their family-caregivers, will be collected through semi-structured interviews to evaluate the feasibility of the exercise training intervention. Depending on the findings during the feasibility testing, the exercise training intervention may change.\n\nDATA ANALYS AND STATISTIC A mixed method approach will be used to meet the aims of the project and collect both quantitative and qualitative data.",[319,320],"Children With Cerebral Palsy Who Are Ambulant","Cerebral Palsy GMFCS-ER I-II",[153,322,323,324,325,326,327,328],"Cerebral Palsy","Exercise","Feasibility","MICT","HIIT","eHealth","Home based exercise","2025-06-15",{"date":331,"type":38},"2025-06-17",{"date":333,"type":38},"2025-05-01",{"date":335,"type":23},"2027-12-31",{"name":44,"class":45},{"id":338,"slug":339,"hasResults":12,"nctId":340,"briefTitle":341,"officialTitle":341,"acronym":342,"eligibilityCriteria":343,"healthyVolunteers":12,"sex":18,"minAge":54,"maxAge":4,"enrollmentInfo":344,"targetDuration":4,"studyType":24,"phases":345,"briefSummary":346,"conditions":347,"keywords":349,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":353,"lastUpdatePostDateStruct":354,"startDateStruct":356,"completionDateStruct":358,"leadSponsor":360,"locationsCount":46},"100481829","the-effect-of-physical-activity-on-postural-orthostatic-tachycardia-syndrome-100481829","NCT05554107","The Effect of Physical Activity on Postural Orthostatic Tachycardia Syndrome","POTS","Inclusion Criteria:\n\n* Patients diagnosed with POTS who have given written informed consent for participation in the study.\n\nExclusion Criteria:\n\n* Patients with myalgic encephalomyelitis are excluded from the study.",{"count":56,"type":23},[26],"Postural orthostatic tachycardia syndrome (POTS) is a disorder of unknown origin characterized by orthostatic intolerance and increased heart rate (HR) of ≥ 30 beats\u002Fminute during orthostasis in the absence of orthostatic hypotension. In addition to the orthostatic intolerance and tachycardia, patients with POTS experience several debilitating symptoms including light-headedness, nausea, blurred vision, fatigue, mental confusion (\"brain-fog\"), chest pain and gastrointestinal problems. Several potential underlying mechanisms have been suggested for POTS including autonomic denervation, hypovolemia, hyperadrenergic stimulation and autoantibodies against adrenergic receptors. However, none of these proposed mechanisms has yet led to an effective treatment. Physical activity is recommended as a complimentary treatment in POTS in international guidelines. However, less is known regarding how physical activity could successfully be implemented in clinical practice in patients with POTS. Thus, in the current study, we aim to assess the effect of a 16-week specialized physical activity program in POTS.",[348],"POTS - Postural Orthostatic Tachycardia Syndrome",[323,342,350,351,352],"Training programme","Treatment","Orthostatic intolerance","2025-05-26",{"date":355,"type":38},"2025-05-30",{"date":357,"type":38},"2022-11-02",{"date":359,"type":23},"2028-10",{"name":44,"class":45},{"id":362,"slug":363,"hasResults":12,"nctId":364,"briefTitle":365,"officialTitle":365,"acronym":4,"eligibilityCriteria":366,"healthyVolunteers":12,"sex":18,"minAge":367,"maxAge":368,"enrollmentInfo":369,"targetDuration":4,"studyType":263,"phases":4,"briefSummary":371,"conditions":372,"keywords":375,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":379,"lastUpdatePostDateStruct":380,"startDateStruct":382,"completionDateStruct":384,"leadSponsor":386,"locationsCount":46},"100540855","promoting-childrens-participation-in-conventional-x-ray-examinations-100540855","NCT06322264","Promoting Children's Participation in Conventional X-ray Examinations","Inclusion Criteria:\n\n* Children ages 4-12 yrs who undergo standard x-ray examinations\n* parents to the child\n* assigned radiographers\n\nExclusion Criteria:\n\n* Children and parents who have cognitive and\u002For language difficulties","4 Years","12 Years",{"count":370,"type":23},220,"The goal of this explorative observational study is to map the procedure and child centered approach in the examination for children that undergo conventional X-ray examinations. The main questions aim to answer:\n\n* How many images need to be retaken during conventional X-ray examinations?\n* What is the reason why the pictures need to be redone?\n* What is the time required for the various examinations?\n* What experience of the procedure of the examination is there among those involved?\n* Can the physical impact be observed through variation in heart rate in children that undergo conventional X-ray examinations?\n\nParticipants will answer questionnaires about the children's participation in the procedure and the variation in heart rate will be measured on the children who undergo the examinations.",[373,374],"Heart Rate Determination","Patient Participation",[376,377,378],"Children's participation","Conventional x-ray procedure","Variation in heart rate","2025-04-15",{"date":381,"type":38},"2025-04-18",{"date":383,"type":38},"2024-11-05",{"date":385,"type":23},"2026-12-10",{"name":44,"class":45},{"id":388,"slug":389,"hasResults":12,"nctId":390,"briefTitle":391,"officialTitle":392,"acronym":4,"eligibilityCriteria":393,"healthyVolunteers":12,"sex":18,"minAge":54,"maxAge":4,"enrollmentInfo":394,"targetDuration":4,"studyType":24,"phases":395,"briefSummary":396,"conditions":397,"keywords":399,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":405,"lastUpdatePostDateStruct":406,"startDateStruct":408,"completionDateStruct":410,"leadSponsor":412,"locationsCount":46},"100573721","an-n-of-1-trial-of-an-internet-delivered-cbt-program-based-on-the-psychological-flexibility-model-of-chronic-pain-for-cancer-related-difficulties-100573721","NCT06749964","An N-of-1 Trial of an Internet-delivered CBT Program Based on the Psychological Flexibility Model of Chronic Pain for Cancer-related Difficulties","Cancer-related Pain and Associated Difficulties: Using Ecological Momentary Assessment and N-of-1 Trial Methods to Adapt and Pilot Test an Internet-delivered CBT Program Based on the Psychological Flexibility Model of Chronic Pain","Inclusion Criteria:\n\n* Current or previous former cancer diagnosis;\n* Recurring cancer-related pain;\n* Aged 18 years or older;\n* Living in Sweden;\n* Fluent in Swedish;\n* Possession of a smartphone where they can download the application necessary for the daily diary recordings;\n* Access to a device with internet access to receive the intervention;\n* Not receiving another psychological treatment.\n\nExclusion Criteria:\n\n\\- Not meeting any of the above inclusion criteria.",{"count":236,"type":23},[26],"Chronic pain is a commonly occurring complication of cancer and can have negatively impact day-to-day functioning and well-being. The recommended treatment for all forms of chronic pain is cognitive behavioral therapy (CBT). However, access to this treatment in primary and specialist care is limited, including access to specialist pain clinics that do not routinely accept people with cancer-related pain. In addition, we know from clinical trials of pain-focused CBT that the symptom presentation of patients can vary greatly and may require interventions that are more tailored to their specific needs.\n\nThe primary objective of the research is to test the feasibility, acceptability and preliminary efficacy of an internet-delivered, therapist-assisted, intervention for chronic pain with adults suffering from chronic cancer-related pain. The intervention is a form of CBT called Acceptance Commitment Therapy (ACT) and is based on the psychological flexibility model of pain. Psychological flexibility refers to an overall pattern of persistent behaviors characterized by a present-moment focus, acceptance rather than avoidance of distressing symptoms, and engagement with one's core values and goals. The intervention aims to improve overall functioning and well-being by helping participants to develop persistent patterns of behavior that align with with their core values and goals (e.g., personal, family, social, health, occupational) despite the presence of pain and other distressing symptoms.\n\nTo achieve this aim, an existing pain-focused, internet-delivered, psychological flexibility based intervention was modified specifically for cancer-related pain with input from cancer patients and survivors. The 8-session, online intervention involves a mixture of written, audio, and videotaped materials, and instructions for experiential exercises, all of which are designed to reduce unhelpful coping behaviors and to increase psychological flexibility. Participants receive written support (and ask questions) from a therapist via the online platform where the intervention is hosted. Where necessary, participants may also access a limited number of face-to-face meetings (online) with their therapist. During the treatment phase, information from daily diary recordings (via smartphone) are used to provide individualized support to participants in the form of text messages from a therapist via the online platform. Where necessary, a limited number of face-to-face sessions (online) with a therapist are scheduled.",[398],"Chronic Cancer-related Pain",[400,401,402,403,404],"chronic cancer-related pain","psychological flexibility","internet delivered cognitive behavioral therapy","n-of-1 design","mediation","2025-03-31",{"date":407,"type":38},"2025-04-03",{"date":409,"type":38},"2025-03-05",{"date":411,"type":23},"2026-06-01",{"name":44,"class":45},{"id":414,"slug":415,"hasResults":12,"nctId":416,"briefTitle":417,"officialTitle":418,"acronym":4,"eligibilityCriteria":419,"healthyVolunteers":174,"sex":420,"minAge":313,"maxAge":4,"enrollmentInfo":421,"targetDuration":4,"studyType":24,"phases":423,"briefSummary":424,"conditions":425,"keywords":427,"overallStatus":432,"whyStopped":4,"lastUpdateSubmitDate":433,"lastUpdatePostDateStruct":434,"startDateStruct":436,"completionDateStruct":438,"leadSponsor":440,"locationsCount":46},"100575645","effect-of-neck-training-on-outcomes-related-to-sport-related-concussion-100575645","NCT06774976","Effect of Neck Training on Outcomes Related to Sport-Related Concussion","Efficacy and Acceptability of an Evidence-Based Neck Resistance Training Program on Head Acceleration and Isometric Neck Strength in Female Soccer Players: A Pilot Quasi-Experimental Trial","Inclusion Criteria:\n\n* Teams that are located in Skåne county\n* Teams that are trained by professional trainers who are financially compensated for their work\n* Teams that are not engaged in any targeted neck-strengthening exercises during the trial period beyond those prescribed within the trial\n* Players that are 16 years of age or older\n* Players that regularly attend all senior-level team activities, including training and match sessions\n* Players that free of any injuries to their upper or lower limbs, torso, neck, or head at the time of enrolment\n* Players with no history of undiagnosed neck pain within the previous three months.","FEMALE",{"count":422,"type":23},50,[26],"Sport-related concussion (SRC) is a significant concern in soccer. This pilot quasi-experimental trial aims to investigate the efficacy and acceptability of an evidence-based neck resistance exercise program in female soccer athletes for SRC prevention. The 8-week intervention includes dynamic and static neck exercises designed to reduce linear and rotational head accelerations, improve neck muscle strength, and minimise SRC risk. The study will evaluate program outcomes through laboratory testing, questionnaires, and user feedback. Findings from this pilot study will inform the design and implementation of a full-scale study, aiming to advance preventive strategies in SRC and address the underrepresentation of female athletes in research.",[426],"Sport-related Concussion",[428,429,430,431],"Sport-related concussion","Neck muscles","Primary prevention","Resistance training","NOT_YET_RECRUITING","2025-03-14",{"date":435,"type":38},"2025-03-17",{"date":437,"type":23},"2025-09",{"date":439,"type":23},"2026-12",{"name":44,"class":45},{"id":442,"slug":443,"hasResults":12,"nctId":444,"briefTitle":445,"officialTitle":446,"acronym":4,"eligibilityCriteria":447,"healthyVolunteers":12,"sex":420,"minAge":54,"maxAge":4,"enrollmentInfo":448,"targetDuration":4,"studyType":263,"phases":4,"briefSummary":450,"conditions":451,"keywords":455,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":433,"lastUpdatePostDateStruct":459,"startDateStruct":460,"completionDateStruct":462,"leadSponsor":463,"locationsCount":46},"100543215","effects-of-tuberculosis-infection-on-development-and-function-of-the-placenta-100543215","NCT06352970","Effects of Tuberculosis Infection on Development and Function of the Placenta","Effects of Tuberculosis Infection on Placental Development and Function","Inclusion Criteria:\n\n* Women admitted for delivery to study sites\n* Written informed consent\n* Age 18 years or greater\n\nExclusion Criteria:\n\n* Chronic comorbidities (other than TB, HIV or pregnancy-related disorder)\n* Twin pregnancy",{"count":449,"type":23},500,"The goal of this observational study is to understand how tuberculosis (TB) infection impacts the function and development of the placenta, and whether TB infection can contribute to pregnancy-related disorders through effects on the placenta.\n\nThe main questions it aims to answer are:\n\n* Does TB infection affect the structure of the placenta?\n* Does TB infection affect the function of the placenta?\n\nPregnant women attending delivery clinics in Addis Abeba, Ethiopia, will be enrolled and classified for TB infection using a blood-based test. We will compare the following outcomes between women with TB infection and women without TB infection:\n\n* Pathological lesions of the placenta\n* Gene and protein expression patterns linked to pregnancy-related disorders\n* Infant outcome at birth and at 6 weeks after birth",[452,453,454],"Pregnancy Related","Tuberculosis Infection","Placenta Diseases",[456,457,458],"placenta","tuberculosis","pregnancy complication",{"date":435,"type":38},{"date":461,"type":38},"2024-10-01",{"date":335,"type":23},{"name":44,"class":45},{"id":465,"slug":466,"hasResults":12,"nctId":467,"briefTitle":468,"officialTitle":469,"acronym":4,"eligibilityCriteria":470,"healthyVolunteers":174,"sex":18,"minAge":471,"maxAge":4,"enrollmentInfo":472,"targetDuration":4,"studyType":24,"phases":473,"briefSummary":474,"conditions":475,"keywords":477,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":484,"lastUpdatePostDateStruct":485,"startDateStruct":487,"completionDateStruct":489,"leadSponsor":491,"locationsCount":492},"100578112","a-municipality-implemented-behavioural-intervention-to-improve-quality-of-life-among-older-adults-100578112","NCT06807060","A Municipality Implemented Behavioural Intervention to Improve Quality of Life Among Older Adults","A Municipality Implemented Behavioural Intervention to Improve Quality of Life Among Older Adults: Protocol for a Mixed-Methods Pilot Case Study","Inclusion Criteria:\n\n* aged 70 and over, ambulatory and sighted,\n* Swedish speaking,\n* living independently in one-person households in ordinary apartments and\n* receiving no or limited home care services.\n\nExclusion Criteria:\n\nStudy participants will be excluded if they have any condition that makes it difficult to participate.","70 Years",{"count":210,"type":23},[26],"Ageing is associated with circadian rhythm sleep disorders, poor sleep at night, less physical activity and more time spent indoors, affecting the wellbeing of older adults. Their sleep and mood could benefit from daytime outdoor physical activity, exposure to daylight, better indoor lighting and sleep routines. However, maintaining or increasing one's physical activity can be challenging depending on individual behavioural conditions, e.g., having the physical and cognitive capacity (capability), finding the activity enjoyable and relevant to one's needs (motivation), and having a supportive social and physical environment (opportunity), such as a walk-friendly environment. To address these challenges, a complex behavioural intervention was developed. The intervention is delivered as a web-based course ('Light, activity and sleep in my daily life', LAS) that targets light-related behaviour, outdoor walking and sleep behaviour among community-dwelling older adults. This protocol describes a pilot case study aiming to evaluate the usability and usefulness of the LAS intervention, the intervention outcomes and whether changes to routines are sustained.\n\nEligible intervention participants (target N=40) are Swedish-speaking adults (≥ 70 years), living in one-person households in apartments in four municipalities. Participants complete questionnaires assessing intervention outcome measures (e.g., quality of life), are interviewed about their daily routines, and wear an accelerometer which tracks activity and rest at the baseline. Participants then enrol in a 9-week course, including self-studies at home and four physical meetings at the senior citizen meeting point. Baseline measures are repeated after the course, at 3, 6 and 10 months after baseline. In addition, participants evaluate the intervention's usability and usefulness after the course at 3 months and are interviewed at 6 months after baseline about perceived enablers and inhibitors to daytime outdoor walking.\n\nResults will inform a subsequent larger case study focused on optimising the LAS intervention's content and delivery procedures to enable an intervention better integrated into municipal health promotion services\u002Fstrategies. An anticipated long-term outcome is continued active ageing and independence.",[476],"Quality of Life",[478,479,480,481,482,476,483],"Complex intervention","Behavioural change","Environmental proactivity","Older adults","Usability","Daytime outdoor walking","2025-01-31",{"date":486,"type":38},"2025-02-04",{"date":488,"type":38},"2024-05-15",{"date":490,"type":23},"2026-10-16",{"name":44,"class":45},4,{"id":494,"slug":495,"hasResults":12,"nctId":496,"briefTitle":497,"officialTitle":498,"acronym":499,"eligibilityCriteria":500,"healthyVolunteers":12,"sex":18,"minAge":54,"maxAge":4,"enrollmentInfo":501,"targetDuration":4,"studyType":263,"phases":4,"briefSummary":503,"conditions":504,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":507,"lastUpdatePostDateStruct":508,"startDateStruct":510,"completionDateStruct":512,"leadSponsor":514,"locationsCount":46},"100502410","carotid-plaque-imaging-project-cpip-100502410","NCT05821894","Carotid Plaque Imaging Project (CPIP)","Carotid Plaque Imaging Project (Identification of Vulnerable Atherosclerotic Plaques With Imaging and Biological Markers)","CPIP","Inclusion Criteria:\n\n* Patients older than 18 years old, male or female that are eligible for carotid endarterectomy due to atherosclerosis and that can provide informed consent.\n\nExclusion Criteria:\n\n* Patients younger than 18 years old that cannot provide informed consent; pregnant.",{"count":502,"type":23},3500,"The rupture or erosion of an atherosclerotic plaque with thrombosis or embolization often underlie heart attacks and strokes. The early identification of patients with atherosclerotic plaques prone to rupture or erosions, vulnerable plaques (VP), and their treatment before the occurrence of events is, therefore, one of the greatest cardiovascular challenges today. Possible approaches for early detection of VP include imaging techniques allowing visualization of plaque structure, circulating biomarkers and better understanding of the pathophysiologic mechanisms of the disease. In the carotid plaque imaging project the investigators study human atherosclerotic plaques (that are removed by endarterectomy) to disclose their underlying structure and mechanisms, finding possible novel therapeutic targets or markers for VP. The investigators also study plaque structure with imaging methods and try to develop new ways to detect VP using circulating or imaging markers.",[505,506],"Atherosclerosis","Atherosclerotic Plaque","2024-10-09",{"date":509,"type":38},"2024-10-15",{"date":511,"type":38},"2005-10-26",{"date":513,"type":23},"2029-12",{"name":44,"class":45},{"id":516,"slug":517,"hasResults":12,"nctId":518,"briefTitle":519,"officialTitle":519,"acronym":4,"eligibilityCriteria":520,"healthyVolunteers":12,"sex":18,"minAge":54,"maxAge":471,"enrollmentInfo":521,"targetDuration":4,"studyType":24,"phases":523,"briefSummary":525,"conditions":526,"keywords":530,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":533,"lastUpdatePostDateStruct":534,"startDateStruct":536,"completionDateStruct":538,"leadSponsor":540,"locationsCount":46},"100295884","phase-3-treatment-of-gravesophthalmopathy-with-simvastatin-go-s-100295884","NCT03131726","Treatment of Graves´ophthalmopathy with Simvastatin (GO-S)","Inclusion Criteria:\n\n1. Age 18-70 years\n2. Active mild to moderate with at least one sign of mild GO (NO SPECS class 2a and b) with reference to Colour Atlas at EUGOGO website (www.eugogo.eu). Exophthalmos up to 24 mm with a disease duration of \\\u003C18 months (as recorded by the patient)\n3. Graves´ disease with clinical and laboratory euthyroidism after stopping treatment with anti thyroid drugs (ATD), or 2 months treatment with ATD, or euthyroid 6 months after treatment with radioiodine, or euthyroid after total thyroidectomy. Clinical and laboratory euthyroidism is defined as normal fT4, fT3 and TSH below the upper limit of the local reference interval and no clinical symptoms or signs of hyperthyroidism. L-thyroxine is used to achieve euthyroidism during the study period.\n\nExclusion Criteria:\n\n1. Pregnancy or breast-feeding\n2. Previous treatment of Graves´ ophthalmopathy\n3. Severe Graves ophthalmopathy requiring corticosteroid treatment, retrobulbar irradiation, orbital decompression surgery\n4. Current or previous treatment with simvastatin or other statins (within 3 months)\n5. Allergy (skin rash or systemic reactions) to statins\n6. Congestive heart failure\n7. Renal insufficiency (glomerular filtration rate \\\u003C60 ml\u002Fmin)\n8. ASAT or ALAT \\> 2.5 times the upper limit of the local laboratory\n9. Alcoholism as judged by local criteria\n10. Coagulopathy including treatment with warfarin or new oral anti-coagulation drugs\n11. Previous or current gastric ulcer\n12. Inflammatory bowel disease diabetic retinopathy or nephropathy\n13. Trauma within 10 days",{"count":522,"type":23},80,[524],"PHASE3","In an investigator initiated multicenter trial (Malmö, Odense, Århus) the investigators aim at evaluating activity of Graves´ophthalmopathy (GO) and progress to severe GO in patients with mild to moderate Graves´ ophthalmopathy treated with simvastatin or no treatment.",[527,528,529],"Graves Ophthalmopathy","Thyroid Associated Ophthalmopathy","Thyroid Associated Orbitopathy",[531,532],"simvastatin","diclofenac","2024-09-23",{"date":535,"type":38},"2024-09-25",{"date":537,"type":38},"2018-01-26",{"date":539,"type":23},"2028-03-30",{"name":44,"class":45},{"id":542,"slug":543,"hasResults":12,"nctId":544,"briefTitle":545,"officialTitle":546,"acronym":4,"eligibilityCriteria":547,"healthyVolunteers":12,"sex":420,"minAge":313,"maxAge":548,"enrollmentInfo":549,"targetDuration":551,"studyType":263,"phases":4,"briefSummary":552,"conditions":553,"keywords":559,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":565,"lastUpdatePostDateStruct":566,"startDateStruct":568,"completionDateStruct":570,"leadSponsor":572,"locationsCount":46},"100543111","epidemiology-of-injuries-in-the-professional-womens-swedish-national-icehockey-league-permitted-to-body-checking-100543111","NCT06351618","Epidemiology of Injuries in the Professional Women's Swedish National IceHockey League Permitted to Body-Checking","Swedish Female Ice Hockey Injury Study","Inclusion Criteria:\n\n* minimum 16 years of age, registered player in the highest Swedish professional ice hockey league for women, SDHL\n\nExclusion Criteria:\n\n* age under 16 years.","110 Years",{"count":550,"type":23},225,"5 Years","This research project can contribute to a deeper understanding of injury patterns among professional female ice-hockey players allowed to body check. An understanding of common injury types and mechanisms aids the clinician in diagnosis and management. This information can guide preventative strategies in the areas of education, coaching, rule enforcement, rule modifications, equipment improvement, and sportsmanship. Today, ice hockey is a sport associated with many severe injuries that not only causes suffering and lower quality of life for the athlete, but also costs society a lot of money. Reducing the number and severity of sport-related injuries is therefore of importance. Knowledge of the injury epidemiology of women's hockey could also contribute to better preventive training programs and other injury preventive actions in the sport. Currently, only a minority of all sports medicine research is made on female study participants (26). This research project has the possibility to gain more knowledge about the female athlete, not only applicable for elite hockey-players, but also for female athletes in different disciplines and in youth teams. Knowledge of factors associated with injury could also contribute to better injury preventive actions and highlight subgroups in extra need of future preventive interventions.",[554,555,556,557,558],"Sport Injury","Ice-Skates Accident","Sports Accident","Female Athlete Triad","Female",[560,561,562,563,564],"women's health","Ice hockey","Elite sport","Injuries","Bodychecking","2024-04-02",{"date":567,"type":38},"2024-04-08",{"date":569,"type":38},"2023-12-01",{"date":571,"type":23},"2028-01-01",{"name":44,"class":45},{"id":574,"slug":575,"hasResults":12,"nctId":576,"briefTitle":577,"officialTitle":578,"acronym":4,"eligibilityCriteria":579,"healthyVolunteers":12,"sex":18,"minAge":54,"maxAge":580,"enrollmentInfo":581,"targetDuration":4,"studyType":263,"phases":4,"briefSummary":583,"conditions":584,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":591,"lastUpdatePostDateStruct":592,"startDateStruct":594,"completionDateStruct":596,"leadSponsor":598,"locationsCount":492},"100493518","early-neuroprognostication-after-ohca-100493518","NCT05706194","Early Neuroprognostication After OHCA","Early Neurological Prognostication of Outcome After Out-of-hospital Cardiac arrest-a STEPCARE Prospective Substudy","Inclusion Criteria:\n\nAdult cardiac arrest patients with an out-of-hospital cardiac arrest of non-traumatic cause treated at hospitals recruiting patients to the STEPCARE neuroprognostication substudy. Other inclusion criteria include:\n\n* a minimum of 20 minutes without chest compressions\n* Unconsciousness defined as not being able to obey verbal commands (FOUR-score motor response of \\\u003C4) or being intubated and sedated because of agitation after sustained ROSC\n* Eligible for intensive care without restrictions or limitations\n* Inclusion within 4 hours of ROSC\n\nExclusion Criteria:\n\n* On ECMO prior to randomisation\n* Pregnancy\n* Suspected or confirmed intracranial hemorrhage\n* Previously randomised in the STEPCARE trial\n* Patients with limitations in level-of-care due to for example generalized malignancy","100 Years",{"count":582,"type":23},1000,"This is a prospective observational substudy of the STEPCARE trial ClinicalTrials.gov Identifier: NCT05564754) with the aim to examine whether prognostication of neurological outcome after cardiac arrest can be performed earlier than the 72 h time-point recommended by guidelines today.",[585,586,587,588,589,590],"Cardiac Arrest","Neurological Outcome","EEG","CT","Brain Injuries","Biomarkers","2024-03-20",{"date":593,"type":38},"2024-03-21",{"date":595,"type":38},"2023-10-01",{"date":597,"type":23},"2029-07-31",{"name":44,"class":45},{"id":600,"slug":601,"hasResults":12,"nctId":602,"briefTitle":603,"officialTitle":604,"acronym":605,"eligibilityCriteria":606,"healthyVolunteers":12,"sex":18,"minAge":4,"maxAge":4,"enrollmentInfo":607,"targetDuration":4,"studyType":263,"phases":4,"briefSummary":609,"conditions":610,"keywords":612,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":630,"lastUpdatePostDateStruct":631,"startDateStruct":633,"completionDateStruct":635,"leadSponsor":637,"locationsCount":638},"100232625","sweden-cancerome-analysis-network---breast--genomic-profiling-of-breast-cancer-100232625","NCT02306096","Sweden Cancerome Analysis Network - Breast : Genomic Profiling of Breast Cancer","SCAN-B: The Sweden Cancerome Analysis Network - Breast Initiative","SCAN-B","Inclusion Criteria:\n\n* suspicion or confirmed diagnosis of primary breast cancer\n* signed informed consent\n\nExclusion Criteria:\n\n* lack of signed informed consent",{"count":608,"type":23},20000,"This study evaluates the genomic profiles of breast cancer in a prospective and population-based manner. In the first phase, breast tumors are analyzed by whole transcriptome RNA-sequencing. Gene expression profiles, mutational profiles, and transcript isoform-level data will be analyzed in the context of patient information, clinicopathological variables, and outcome, with the purpose to develop new molecular diagnostic assays for breast cancer. Additional genome-scale RNA, DNA, and protein analyses will be performed in the future.",[611],"Breast Neoplasms",[613,614,615,616,617,618,619,620,621,622,623,624,625,626,627,628,629],"prognostic and predictive biomarkers","RNA-sequencing","pathological complete response","minimal residual disease","molecular subtype","gene expression profiling","mutation screening","BRCA","translational research","genomics","transcriptomics","proteomics","metabolomics","liquid biopsy","circulating tumor cells","circulating tumor DNA","RNA-seq","2024-02-07",{"date":632,"type":38},"2024-02-09",{"date":634,"type":4},"2010-08",{"date":636,"type":23},"2031-08",{"name":44,"class":45},9,{"id":640,"slug":641,"hasResults":12,"nctId":642,"briefTitle":643,"officialTitle":644,"acronym":4,"eligibilityCriteria":645,"healthyVolunteers":174,"sex":18,"minAge":646,"maxAge":54,"enrollmentInfo":647,"targetDuration":4,"studyType":24,"phases":649,"briefSummary":650,"conditions":651,"keywords":653,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":655,"lastUpdatePostDateStruct":656,"startDateStruct":658,"completionDateStruct":660,"leadSponsor":662,"locationsCount":46},"100318432","acoustic-and-vestibular-noise-as-possible-non-pharmacological-treatment-of-adhd-in-school-children-100318432","NCT03425669","Acoustic and Vestibular Noise as Possible Non-pharmacological Treatment of ADHD in School Children","Acoustic and Vestibular Noise as Possible Non-pharmacological Treatments of ADHD in School Children","Inclusion Criteria: Children and adolescents with a diagnosis of ADHD and control children without at diagnosis.\n\n\\-\n\nExclusion Criteria: Intellectual disability, psychosis, severe depression or anxiety\n\n\\-","9 Years",{"count":648,"type":23},70,[26],"Noise benefit in ADHD Auditory noise benefit: The original findings from our research group, that auditory noise enhances cognitive performance in inattentive children without diagnosis as well as children with an ADHD diagnosis, have been replicated several times (Baijot et al., 2016; Söderlund et al., 2016; Söderlund \\& Nilsson Jobs, 2016; Söderlund et al., 2007). In a new study, the benefit of noise was shown to be in parity with or even larger than the benefit of pharmacological ADHD treatment on two cognitive tasks, episodic word recall and visuo-spatial working memory task. In the study a group of children diagnosed with ADHD were tested on and off medication, at separate occasions, in noisy vs. silent environments while performing the tasks (Söderlund, Björk et al., 2016).\n\nParticipants and recruitment: Participants with an ADHD diagnosis using medication will be recruited from Child and Adolescent Psychiatry in Lund and Malmö. Typically developing children (TDC) and inattentive children without diagnosis will be recruited from schools in collaboration with the municipality.\n\nExperimental design: All participants will perform a double-blind placebo cross over control study. ADHD participants will perform the entire test battery at three occasions with 2-3 weeks intermission in between tests. One occasion with placebo medication and sham SVS stimulation; one occasion with active SVS stimulation; and one occasion with active medication. TD children will only be tested twice while they will not be given any medication or placebo and just perform under SVS vs. sham conditions.\n\nTest battery: 1) Episodic memory will be tested trough Auditory Verbal Learning Test (AVLT) (e.g. Dige et al., 2008). 2) Visuo-spatial working memory will be tested through the Spanboard task (Westerberg et al., 2004). 3) Motor-neurological investigation. 4) A finger tapping task. 5) Evaluation of an iPhone auditory noise application in a normal school setting. Our research group has developed an iPhone application (www.smartnoise.se) that is available at App-store right now. The study will last for about 5 months and participants will be 50 voluntary secondary school pupils that have documented attention difficulties as judged by their teachers. The application will be evaluated both by pupils, teachers and parents.",[652],"ADHD",[654],"Acoustic and vestibular noise stimulation","2023-10-10",{"date":657,"type":38},"2023-10-11",{"date":659,"type":38},"2019-05-01",{"date":661,"type":23},"2027-05-31",{"name":44,"class":45},{"id":664,"slug":665,"hasResults":12,"nctId":666,"briefTitle":667,"officialTitle":668,"acronym":669,"eligibilityCriteria":670,"healthyVolunteers":12,"sex":18,"minAge":54,"maxAge":4,"enrollmentInfo":671,"targetDuration":4,"studyType":263,"phases":4,"briefSummary":673,"conditions":674,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":676,"lastUpdatePostDateStruct":677,"startDateStruct":679,"completionDateStruct":681,"leadSponsor":683,"locationsCount":46},"100492026","agreement-and-reliability-of-transient-elastography-100492026","NCT05686785","Agreement and Reliability of Transient Elastography","Agreement and Reliability of Transient Elastography in Patients With Chronic Viral Hepatitis - a Cross-sectional Test-retest Study","HEPSCAN","Inclusion Criteria:\n\n* Patients at the departments of infectious diseases in Malmö, Lund and Helsingborg with chronic viral hepatitis.\n* Adult patients\n* Signed informed consent to participate in the study.\n\nExclusion Criteria:\n\n* suspected or confirmed pregnancy.\n* patients unable to speak Swedish\n* inability to sign informed consent.",{"count":672,"type":23},300,"The aim of this study is to assess agreement, smallest detectable change, and reliability of repeated measurements of liver stiffness of transient elastography in patients with chronic viral hepatitis, and to explore factors associated with disagreement.",[675],"Chronic Viral Hepatitis","2023-10-02",{"date":678,"type":38},"2023-10-04",{"date":680,"type":38},"2023-06-01",{"date":682,"type":23},"2026-12-01",{"name":44,"class":45},{"id":685,"slug":686,"hasResults":12,"nctId":687,"briefTitle":688,"officialTitle":689,"acronym":690,"eligibilityCriteria":691,"healthyVolunteers":12,"sex":18,"minAge":54,"maxAge":692,"enrollmentInfo":693,"targetDuration":4,"studyType":24,"phases":695,"briefSummary":696,"conditions":697,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":701,"lastUpdatePostDateStruct":702,"startDateStruct":704,"completionDateStruct":706,"leadSponsor":708,"locationsCount":129},"100456500","phase-3-pivmecillinam-with-amoxicillinclavulanic-acid-for-step-down-oral-therapy-in-esbl-utis-100456500","NCT05224401","Pivmecillinam With Amoxicillin\u002FClavulanic Acid for Step Down Oral Therapy in ESBL UTIs","Pivmecillinam With Amoxicillin\u002FClavulanic Acid for Step Down Oral Therapy in Febrile UTIs Caused by ESBL-producing Enterobacterales (PACUTI)","PACUTI","Inclusion Criteria:\n\n1. Age ≥ 18 years\n2. Fever (≥ 38.3 C) or shaking chills at least once at home or in hospital\n3. Clinical suspicion of UTI including at least one of the following symptoms:\n\n   1. Dysuria, urinary urgency, difficulty urinating, new or worsened urinary incontinence, macroscopic haematuria or increased urinary frequency\n   2. Low abdominal pain or flank pain with percussion or palpation tenderness over kidneys and\u002For bladder.\n4. Urine (≥ 103 CFU\u002FmL) and\u002For blood culture positive for EPE\\* with susceptibility to pivmecillinam†.\n5. In-patient who has received 1-5 days of EPE-active‡ intravenous antibiotics\n6. Discontinuing parenteral treatment and starting treatment with oral antibiotics is considered safe according to the treating physician.\n\n   * EPE refers to ESBL-producing Enterobacterales. This includes Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis, Klebsiella oxytoca, and Citrobacter koseri.\n\n     * Susceptibility for pivmecillinam in the study is based on zone diameter breakpoints for pyelonephritis (≥ 20 mm) which was received by personal communication with professor Christian Giske, the chairman of the European Committee of Antimicrobial Susceptibility Testing (EUCAST) (26).\n\n       * EPE-active intravenous antibiotics refers to EUCAST susceptibility testing and will most often be piperacillin-tazobactam, meropenem or imipenem-cilastatin in the Swedish setting, and less often aminoglycosides or newer beta-lactamase-inhibitor-containing beta-lactam antibiotics (27). Participants who have only received one dose of EPE-active intravenous antibiotics are also eligible and are considered within the \"1-5 days\" of antibiotics.\n\nPatients may only be recruited and randomised once in this trial.\n\nExclusion criteria (any of the following)\n\n1. Known or suspected pregnancy.\n2. Known or suspected life-threatening allergy towards beta-lactam antibiotics.\n3. Clinical isolate of EPE is resistant to ciprofloxacin, TMX and ertapenem.\n4. Severe renal insufficiency with estimated glomerular filtration rate (eGFR) \\\u003C10mL\u002Fmin or requiring any form of dialysis.\n5. Severe decompensated liver failure (i.e., child Pugh class B or C).\n6. Genetic metabolic diseases associated with severe carnitine deficiency.\n7. Megaloblastic haematopoiesis.\n8. Co-treatment with valproate or valproic acid (due to interaction with pivmecillinam and ertapenem respectively)\n9. Other reason to which patient is unfit to be included in the study according to treating physician, e.g., cognitive impairment preventing informed consent and follow-up, inability to speak and\u002For read Swedish, missing national personal identification number or missing telephone number preventing follow-up or planned duration of antibiotics \\> 10 days due to complicating factors.","130 Years",{"count":694,"type":23},330,[524],"To evaluate if the combination of pivmecillinam and clavulanic acid (PAC) is non-inferior to ciprofloxacin, trimethoprim-sulfamethoxazole or ertapenem as step down oral therapy in patients with febrile UTI caused by extended spectrum beta-lactamase (ESBL) producing Enterobacterales (EPE).",[698,699,700],"Urinary Tract Infections","Bacteremia","Antibiotic Resistant Infection","2023-08-25",{"date":703,"type":38},"2023-08-28",{"date":705,"type":38},"2023-05-29",{"date":707,"type":23},"2027-09-01",{"name":44,"class":45},""]